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P. Řezáčová · SciRah

Researcher profile · Semantic Scholar

P. Řezáčová

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P. Řezáčová — researcher profile on SciRah

h-index: 30
Works: 294
Citations: 3,278

Most-cited papers

Metallacarborane sulfamides: unconventional, specific, and highly selective inhibitors of carbonic anhydrase IX.
B. Grüner, J. Brynda, Viswanath Das, V. Šícha +17 more
2019Journal of Medicinal Chemistry61 citations
Semantic Scholar
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
Jana Dvořanová, M. Kugler, J. Holub, V. Šícha +16 more
2020European journal of medicinal chemistry36 citations
Semantic Scholar
N-Glycosylation can selectively block or foster different receptor–ligand binding modes
Joni Vuorio, J. Škerlová, M. Fábry, V. Veverka +3 more
2021Scientific Reports35 citations Open access
Semantic Scholar
The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin
J. Kotál, N. Stergiou, M. Buša, A. Chlastáková +10 more
2019Cellular and Molecular Life Sciences35 citations Open access
Semantic Scholar
3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.
R. Jorda, L. Havlicek, M. Peřina, Veronika Vojáčková +9 more
2022Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds
M. Kugler, Jan Nekvinda, J. Holub, Suzan El Anwar +10 more
2021ChemBioChem28 citations
Semantic Scholar
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
Robin Kryštůfek, P. Šácha, J. Štarková, J. Brynda +12 more
2021Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.
R. Jorda, L. Havlicek, A. Šturc, D. Tušková +13 more
2019Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.
Václav Zima, C. B. Albiñana, K. Rojíková, J. Pokorná +8 more
2019Bioorganic & Medicinal Chemistry23 citations Open access
Semantic Scholar
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
Z. Vavřina, Pavla Perlíková, Nemanja Milisavljevič, F. Chevrier +12 more
2022Journal of Medicinal Chemistry21 citations Open access
Semantic Scholar
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity
A. Jílková, M. Horn, J. Fanfrlík, J. Küppers +9 more
2020ACS Infectious Diseases19 citations Open access
Semantic Scholar
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
Neetu Dayal, E. Řezníčková, Delmis E. Hernandez, M. Peřina +11 more
2021Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Inhibitor–Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms
K. Pospíšilová, Tomáš Knedlík, P. Šácha, L. Kostka +11 more
2019ACS Omega18 citations Open access
Semantic Scholar
Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
B. Grüner, M. Kugler, Suzan El Anwar, J. Holub +8 more
2020ChemPlusChem16 citations
Semantic Scholar
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7
M. Kovalová, L. Havlicek, S. Djukic, J. Škerlová +6 more
2023bioRxiv15 citations Open access
Semantic Scholar
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors
A. Jílková, P. Rubešová, J. Fanfrlík, Pavla Fajtová +10 more
2020ACS Infectious Diseases15 citations Open access
Semantic Scholar
Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy.
P. Srb, M. Svoboda, L. Benda, M. Lepšík +8 more
2019Physical Chemistry, Chemical Physics - PCCP15 citations
Semantic Scholar
Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion
J. Kotál, M. Buša, V. Urbanová, P. Řezáčová +5 more
2021International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.
J. Jansa, R. Jorda, J. Škerlová, P. Pachl +7 more
2021European journal of medicinal chemistry11 citations Open access
Semantic Scholar
Crystal structure of rutinosidase from Aspergillus niger
P. Pachl, P. Řezáčová, J. Kapešová
202011 citations
Semantic Scholar
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX
M. Kugler, J. Holub, J. Brynda, K. Pospíšilová +7 more
2020Journal of Enzyme Inhibition and Medicinal Chemistry11 citations Open access
Semantic Scholar
X-ray structure of human aldo–keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis
Maja Marinović, Sofija S. Bekić, M. Kugler, J. Brynda +5 more
2022RSC Medicinal Chemistry10 citations Open access
Semantic Scholar
Identification of Novel Carbonic Anhydrase IX Inhibitors Using High-Throughput Screening of Pooled Compound Libraries by DNA-Linked Inhibitor Antibody Assay (DIANA)
J. Tykvart, V. Navrátil, M. Kugler, P. Šácha +12 more
2020SLAS discovery : advancing life sciences R & D10 citations Open access
Semantic Scholar
Rutinosidase from Aspergillus niger: Crystal structure and insight into the enzymatic activity.
P. Pachl, J. Kapešová, J. Brynda, L. Biedermannová +5 more
2020The FEBS Journal10 citations
Semantic Scholar
Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
J. Hejdánek, K. Radilová, P. Pachl, J. Hodek +5 more
2020Antiviral Research8 citations Open access
Semantic Scholar
Crystal structure of the cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5.
K. Tratsiak, T. Prudnikova, I. Drienovská, J. Damborský +6 more
2019Acta Crystallographica Section F Structural Biology Communications8 citations Open access
Semantic Scholar
An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily
M. Buša, Zuzana Matoušková, Pavla Bartošová-Sojková, P. Pachl +6 more
2023Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family.
M. Šoltysová, I. Sieglová, M. Fábry, J. Brynda +2 more
2021Acta Crystallographica Section D: Structural Biology7 citations
Semantic Scholar
Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
B. Grüner, M. Kugler, Suzan El Anwar, J. Holub +8 more
2020ChemPlusChem7 citations Open access
Semantic Scholar
ABNOH-Linked Nucleotides and DNA for Bioconjugation and Cross-linking with Tryptophan-Containing Peptides and Proteins.
Ambra Spampinato, D. Leone, R. Pohl, Ján Tarábek +6 more
2024Chemistry6 citations
Semantic Scholar
Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Carboranes; the Influence of Stereochemistry on Inhibitory Activity Against Cancer-associated Carbonic Anhydrase IX Isoenzyme.
Jan Nekvinda, M. Kugler, J. Holub, Suzan El Anwar +5 more
2020Chemistry6 citations
Semantic Scholar
Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family
M. Marek, R. Chaloupkova, T. Prudnikova, Yukari Sato +4 more
2020Computational and Structural Biotechnology Journal6 citations Open access
Semantic Scholar
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
J. Skácel, S. Djukic, O. Baszczyňski, Filip Kalčic +18 more
2023Journal of Medicinal Chemistry5 citations Open access
Semantic Scholar
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.
J. Fanfrlík, J. Brynda, M. Kugler, M. Lepšík +6 more
2023Physical Chemistry, Chemical Physics - PCCP5 citations Open access
Semantic Scholar
Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function
M. Šoltysová, J. Škerlová, P. Pachl, K. Škubník +8 more
2024Nucleic Acids Research4 citations Open access
Semantic Scholar
Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study.
M. Kugler, Martin Hadzima, R. Dzijak, Robert Rampmaier +6 more
2023RSC Medicinal Chemistry4 citations Open access
Semantic Scholar
Structural insights into tick-borne encephalitis virus neutralization and animal protection by a therapeutic antibody
I. Baykov, G. Chojnowski, P. Pachl, A. Matveev +5 more
2021bioRxiv4 citations Open access
Semantic Scholar
A novel structurally characterized haloacid dehalogenase superfamily phosphatase from Thermococcus thioreducens with diverse substrate specificity.
P. Havlíčková, V. Brinsa, J. Brynda, P. Pachl +8 more
2019Acta Crystallographica Section D: Structural Biology4 citations
Semantic Scholar
Affinity and Selectivity of Protein–Ligand Recognition: A Minor Chemical Modification Changes Carbonic Anhydrase Binding Profile
A. Zakšauskas, Vaida Paketurytė-Latvė, Alberta Jankūnaitė, E. Čapkauskaitė +13 more
2025Journal of Medicinal Chemistry3 citations Open access
Semantic Scholar
The structural basis of aldo-keto reductase 1C3 inhibition by 17α-picolyl and 17(E)-picolinylidene androstane derivatives
Jovana J Plavša-Puž, Jiří Brynda, Jovana J. Ajduković, Sofija S. Bekić +4 more
2025Journal of Enzyme Inhibition and Medicinal Chemistry2 citations Open access
Semantic Scholar
Molecular insight into 5′ RNA capping with NpnNs by bacterial RNA polymerase
Valentina M Serianni, J. Škerlová, A. Dubánková, Anton Škríba +7 more
2026Nature Chemical Biology1 citations Open access
Semantic Scholar
Using environment-sensitive tetramethylated thiophene-BODIPY fluorophores in DNA probes for studying effector-induced conformational changes of protein–DNA complexes
M. Šoltysová, Pedro Güixens-Gallardo, I. Sieglová, Anna Soldanova +6 more
2025RSC Chemical Biology1 citations
Semantic Scholar
CDK2-based CDK7 mimic as a tool for structural analysis: Biochemical validation and crystal structure with SY5609.
J. Škerlová, V. Krejčiříková, M. Peřina, Veronika Vojáčková +4 more
2024International Journal of Biological Macromolecules1 citations Open access
Semantic Scholar
Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon.
J. Škerlová, J. Brynda, J. Šobotník, Marek Zakopcanik +4 more
2024Structure1 citations Open access
Semantic Scholar
Evolutionary upgrade of stefins for secretion in parasites
M. Buša, Zuzana Matoušková, P. Řezáčová, Pavla Sojková-Bartošová +3 more
2021Acta Crystallographica Section A: Foundations and Advances1 citations Open access
Semantic Scholar
Steroidal A/B-ring fusion as a strategy for isoform-selective inhibition of human carbonic anhydrases
Jiří Brynda, Anita Kiss, K. Pospíšilová, Vojtěch Kapras +4 more
2026RSC Advances0 citations
Semantic Scholar
Selective inhibition of carbonic anhydrase IX for cancer diagnosis and therapy
Linh H. Ngo, Jiří Brynda, K. Pospíšilová, P. Řezáčová
2026Acta Crystallographica Section A: Foundations and Advances0 citations
Semantic Scholar
Structure and function of bacterial transcription regulators of the SorC family
M. Šoltysová, P. Řezáčová
2024Transcription0 citations Open access
Semantic Scholar
Practical courses on advanced methods in macromolecular crystallization: 20 years of history and future perspectives
P. Havlíčková, J. Gavira, J. Mesters, A. Koutská +6 more
2024Journal of Applied Crystallography0 citations Open access
Semantic Scholar
Protein crystallization and structure determination at room temperature in the CrystalChip
P. Pachl, L. Coudray, R. Vincent, Léa Nilles +6 more
2024FEBS Open Bio0 citations Open access
Semantic Scholar

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