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E. Řezníčková · SciRah

Researcher profile · Semantic Scholar

E. Řezníčková

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E. Řezníčková — researcher profile on SciRah

h-index: 14
Works: 59
Citations: 627

Most-cited papers

How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
R. Jorda, Denisa Hendrychová, Jiří Voller, E. Řezníčková +2 more
2018Journal of Medicinal Chemistry80 citations Open access
Semantic Scholar
A novel series of highly potent 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitors.
T. Gúcky, R. Jorda, Marek Zatloukal, V. Bazgier +5 more
2013Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl- N6-(4-morpholin-4-ylmethyl-phenyl)- 9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations.
T. Gúcky, E. Řezníčková, Tereza Radošová Muchová, R. Jorda +8 more
2018Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases.
Marek Zatloukal, R. Jorda, T. Gúcky, E. Řezníčková +6 more
2013European journal of medicinal chemistry36 citations Open access
Semantic Scholar
Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC).
E. Řezníčková, S. Krajcovicova, M. Peřina, M. Kovalová +2 more
2022European journal of medicinal chemistry29 citations Open access
Semantic Scholar
Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines.
A. Imramovský, R. Jorda, K. Pauk, E. Řezníčková +3 more
2013European journal of medicinal chemistry27 citations Open access
Semantic Scholar
Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance
Christine Haider, M. Grubinger, E. Řezníčková, T. Weiss +9 more
2013Molecular Cancer Therapeutics25 citations Open access
Semantic Scholar
Synthesis and anti-mitotic activity of 2,4- or 2,6-disubstituted- and 2,4,6-trisubstituted-2H-pyrazolo[4,3-c]pyridines.
Vaida Milišiūnaitė, Eglė Arbačiauskienė, E. Řezníčková, R. Jorda +5 more
2018European journal of medicinal chemistry22 citations
Semantic Scholar
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
Neetu Dayal, E. Řezníčková, Delmis E. Hernandez, M. Peřina +11 more
2021Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Synthesis of novel galeterone derivatives and evaluation of their in vitro activity against prostate cancer cell lines.
R. Jorda, E. Řezníčková, Urszula Kiełczewska, Jadwiga Maj +6 more
2019European journal of medicinal chemistry18 citations Open access
Semantic Scholar
Biological Evaluation of Dipyrromethanes in Cancer Cell Lines: Antiproliferative and Pro‐apoptotic Properties
R. Jorda, Susana M. M. Lopes, E. Řezníčková, V. Kryštof +1 more
2017ChemMedChem18 citations Open access
Semantic Scholar
Selective inhibition reveals cyclin-dependent kinase 2 as another kinase that phosphorylates the androgen receptor at serine 81.
R. Jorda, Zuzana Bucková, E. Řezníčková, J. Bouchal +1 more
2018Biochimica et biophysica acta. Molecular cell research17 citations Open access
Semantic Scholar
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7
M. Kovalová, L. Havlicek, S. Djukic, J. Škerlová +6 more
2023bioRxiv15 citations Open access
Semantic Scholar
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping
Petra Břehová, E. Řezníčková, Kryštof Škach, R. Jorda +15 more
2023Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2H-pyrazolo[4,3-c]pyridines
Beatričė Razmienė, E. Řezníčková, Vaida Dambrauskienė, Radek Ostruszka +5 more
2021Molecules15 citations Open access
Semantic Scholar
Tetrahydropyrazolo[1,5-a]pyridine-fused steroids and their in vitro biological evaluation in prostate cancer.
R. Jorda, Susana M. M. Lopes, E. Řezníčková, H. Ajani +3 more
2019European journal of medicinal chemistry15 citations
Semantic Scholar
Synthesis and anticancer activity of some 1,5-diaryl-3-(3,4,5-trihydroxyphenyl)-1H-pyrazolo[4,3-e][1,2,4]triazines
T. Gúcky, E. Řezníčková, P. Džubák, M. Hajdůch +1 more
201014 citations
Semantic Scholar
Characterization of a Pyrazolo[4,3‐d]pyrimidine Inhibitor of Cyclin‐Dependent Kinases 2 and 5 and Aurora A With Pro‐Apoptotic and Anti‐Angiogenic Activity In Vitro
E. Řezníčková, Sabine B. Weitensteiner, L. Havlicek, R. Jorda +6 more
2015Chemical Biology and Drug Design12 citations Open access
Semantic Scholar
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.
J. Jansa, R. Jorda, J. Škerlová, P. Pachl +7 more
2021European journal of medicinal chemistry11 citations Open access
Semantic Scholar
Exploitation of new structurally diverse d-glucuronamide-containing N-glycosyl compounds: synthesis and anticancer potential.
Nuno M. Xavier, Alexandre Porcheron, Daniel C. Batista, R. Jorda +3 more
2017Organic and biomolecular chemistry11 citations Open access
Semantic Scholar
2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro.
E. Řezníčková, A. Popa, T. Gúcky, Marek Zatloukal +9 more
2015Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Synthesis of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines and their photodynamic properties in the human skin melanoma cell line G361.
Beatričė Razmienė, Veronika Vojáčková, E. Řezníčková, L. Malina +8 more
2021Bioorganic chemistry (Print)10 citations
Semantic Scholar
Application of Pd-Catalyzed Cross-Coupling Reactions in the Synthesis of 5,5-Dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles that Inhibit ALK5 Kinase.
L. Tenora, J. Galeta, E. Řezníčková, V. Kryštof +1 more
2016Journal of Organic Chemistry10 citations Open access
Semantic Scholar
Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma
Kristina Breitenecker, Viola Hedrich, Franziska Pupp, Doris Chen +7 more
2023Frontiers in Oncology9 citations Open access
Semantic Scholar
Activity of 2,6,9-trisubstituted purines as potent PDGFRα kinase inhibitors with antileukaemic activity.
E. Řezníčková, T. Gúcky, V. Kováčová, H. Ajani +2 more
2019European journal of medicinal chemistry9 citations Open access
Semantic Scholar
Trisubstituted purine inhibitors of PDGFRα and their antileukemic activity in the human eosinophilic cell line EOL-1.
Veronika Malínková, E. Řezníčková, R. Jorda, T. Gúcky +1 more
2017Bioorganic & Medicinal Chemistry9 citations Open access
Semantic Scholar
First-in-Class Dual PDGFR/Carbonic Anhydrase IX/XII Inhibitors: 6,7-Dimethoxyquinoline-Sulfonamides as Promising Antileukemic Agents
Eslam Roshdy, E. Řezníčková, Mostafa M. Elbadawi, I. Celik +9 more
2026Journal of Medicinal Chemistry8 citations Open access
Semantic Scholar
Synthesis and antiproteasomal activity of novel O-benzyl salicylamide-based inhibitors built from leucine and phenylalanine.
R. Jorda, J. Dušek, E. Řezníčková, K. Pauk +3 more
2017European journal of medicinal chemistry8 citations Open access
Semantic Scholar
Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors.
Mahfam Moradi, Alireza Mousavi, E. Řezníčková, Fariba Peytam +9 more
2024European journal of medicinal chemistry7 citations Open access
Semantic Scholar
Design and synthesis of novel 1,2,4-triazolo[4,3-b]pyridazine derivatives with anti-cancer activity
A. Ganai, T. K. Pathan, S. Mohite, Veronika Vojáčková +9 more
2023Journal of Molecular Structure7 citations
Semantic Scholar
ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles.
E. Řezníčková, L. Tenora, P. Pospisilova, J. Galeta +5 more
2017European journal of medicinal chemistry7 citations Open access
Semantic Scholar
Synthesis and photodynamic activity of new 5‐[(E)‐2‐(3‐alkoxy‐1‐phenyl‐1H‐pyrazol‐4‐yl)ethenyl]‐2‐phenyl‐3H‐indoles
Gabrielė Varvuolytė, E. Řezníčková, Aurimas Bieliauskas, N. Kleizienė +5 more
2024Archiv der Pharmazie6 citations Open access
Semantic Scholar
Anticancer effect of zanubrutinib in HER2-positive breast cancer cell lines
H. Dostálová, R. Jorda, E. Řezníčková, V. Kryštof
2023bioRxiv6 citations Open access
Semantic Scholar
Synthesis and photo-induced anticancer activity of new 2-phenylethenyl-1H-benzo[e]indole dyes.
Gabrielė Varvuolytė, E. Řezníčková, Sonata Krikštolė, Rasa Tamulienė +10 more
2024European journal of medicinal chemistry5 citations Open access
Semantic Scholar
Strategies for the treatment of acute myeloid leukemia with FLT3 mutations: a patent review
L. Górecki, E. Řezníčková, V. Kryštof, Martina Řezáčová +2 more
2024Expert Opinion on Therapeutic Patents5 citations
Semantic Scholar
Development of fluorescent dual-FRET probe for simultaneous detection of caspase-8 and caspase-9 activities and their relative quantification.
Martin Porubský, E. Řezníčková, Soňa Křupková, V. Kryštof +1 more
2022Bioorganic chemistry (Print)5 citations
Semantic Scholar
Synthesis and antiproliferative evaluation of novel azido nucleosides and their phosphoramidate derivatives
Nuno M. Xavier, R. Gonçalves-Pereira, R. Jorda, E. Řezníčková +2 more
20175 citations Open access
Semantic Scholar
Anticancer dinuclear Ir(III) complex activates Nrf2 and interferes with NAD(H) in cancer cells.
E. Řezníčková, Ondřej Bárta, D. Milde, V. Kryštof +1 more
2024Journal of Inorganic Biochemistry4 citations
Semantic Scholar
Synthesis and biological activity evaluation of novel 3,5,7-trisubstituted pyrazolo[1,5-a]pyrimidines.
Kristýna Vlková, Růžena Padrtová, T. Gúcky, M. Peřina +2 more
2022Bioorganic & Medicinal Chemistry Letters4 citations
Semantic Scholar
Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors.
Kristýna Vlková, T. Gúcky, M. Peřina, E. Řezníčková +1 more
2022Bioorganic & Medicinal Chemistry Letters4 citations Open access
Semantic Scholar
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors
Monika Tomanová, Karolína Kozlanská, R. Jorda, Lukáš Jedinák +7 more
2022bioRxiv4 citations Open access
Semantic Scholar
Pseudopeptides with aldehyde or vinylsulfone warheads: Synthesis and antiproteasomal activity.
R. Jorda, Veronika Molitorová, Eliška Pilařová, Veronika Vojáčková +5 more
2021Bioorganic chemistry (Print)4 citations
Semantic Scholar
3H-pyrazolo[4,3-f]quinoline hinge binder, a tunable scaffold for development of novel kinase inhibitors against FLT3-driven leukemia
Neetu Dayal, E. Řezníčková, Delmis E. Hernandez, M. Peřina +9 more
2025European journal of medicinal chemistry3 citations Open access
Semantic Scholar
Synthesis and Antiproliferative Activities of Novel O-Benzyl Salicylamide Derivatives
J. Dušek, A. Imramovský, K. Pauk, R. Jorda +2 more
20173 citations Open access
Semantic Scholar
Synthesis and antimitotic activity of 2-phenyl-6-pyridinyl-2H-pyrazolo[4,3-c]pyridines
Vaida Aleksienė, E. Řezníčková, Aurimas Bieliauskas, Veronika Vojáčková +7 more
2026RSC Advances0 citations Open access
Semantic Scholar
Attack of NADH and ascorbate toward metal-activated ligand of organoiridium(III) compound.
P. Štarha, E. Řezníčková, Slavomíra Šterbinská, Alessandro Marrone +8 more
2026Journal of Inorganic Biochemistry0 citations Open access
Semantic Scholar
Anti-leukemic efficacy of a novel inhibitor for KMT2A-r/FLT3-driven AML via multi-kinase targeting and synergy with menin inhibition
Nikola Niederlova, P. Koralkova, Pavla Chaloupková, L. Janotka +11 more
2025Blood0 citations
Semantic Scholar
Targeting of SFK and G6PD Contributes to Anti-Leukemic Activity of Novel FLT3 Trisubstituted Purine Inhibitors: Effective Therapeutic Approach for AML with FLT3 Mutations
P. Koralkova, Nikola Niederlova, Iveta Hradilová, J. Gursky +8 more
2022Blood0 citations Open access
Semantic Scholar
New 2H-pyrazolo[4,3-c]pyridines: Synthesis, optical properties and elucidation of anti-cancer activity
Beatričė Razmienė, E. Řezníčková, Vaida Dambrauskienė, Eglė Arbačiauskienė +4 more
20200 citations Open access
Semantic Scholar
THU-478-CXCL5 induced by transforming growth factor-beta and Axl signalling causes neutrophil extracellular trap formation in hepatocellular carcinoma
Elisa Holstein, E. Řezníčková, Teresita Flores, H. Heidemarie +4 more
2019Journal of Hepatology0 citations
Semantic Scholar

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