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D. Swerdlow · SciRah

Researcher profile · Semantic Scholar

D. Swerdlow

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D. Swerdlow — researcher profile on SciRah

h-index: 24
Works: 64
Citations: 6,243

Most-cited papers

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
D. Swerdlow, M. Holmes, K. Kuchenbaecker, J. Engmann +112 more
2012The Lancet1,035 citations Open access
Semantic Scholar
Mendelian randomization of blood lipids for coronary heart disease
M. Holmes, F. Asselbergs, T. Palmer, F. Drenos +64 more
2014European Heart Journal745 citations Open access
Semantic Scholar
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
D. Swerdlow, D. Preiss, K. Kuchenbaecker, M. Holmes +129 more
2015The Lancet672 citations Open access
Semantic Scholar
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
Michael V. Holmes, C. Dale, L. Zuccolo, R. Silverwood +151 more
2014British medical journal640 citations Open access
Semantic Scholar
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies
D. Swerdlow, K. Kuchenbaecker, Sonia H. Shah, R. Sofat +8 more
2016International Journal of Epidemiology354 citations Open access
Semantic Scholar
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
A. Schmidt, D. Swerdlow, M. Holmes, R. Patel +129 more
2017The Lancet Diabetes and Endocrinology344 citations Open access
Semantic Scholar
Lipid Fractions and Contrasting Risks of Coronary Artery Disease and Diabetes
Jon White, D. Swerdlow, D. Preiss, Z. Fairhurst-Hunter +6 more
2016JAMA cardiology272 citations Open access
Semantic Scholar
Single Ascending Dose Study of a Short Interfering RNA Targeting Lipoprotein(a) Production in Individuals With Elevated Plasma Lipoprotein(a) Levels.
S. Nissen, K. Wolski, C. Balog, D. Swerdlow +12 more
2022Journal of the American Medical Association (JAMA)271 citations Open access
Semantic Scholar
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
F. Asselbergs, Yi-Ran Guo, E. V. van Iperen, S. Sivapalaratnam +166 more
2012American Journal of Human Genetics258 citations Open access
Semantic Scholar
Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.
M. Holmes, L. Lange, T. Palmer, M. Lanktree +30 more
2014American Journal of Human Genetics231 citations Open access
Semantic Scholar
Mendelian randomization for studying the effects of perturbing drug targets
D. Gill, Marios K. Georgakis, V. Walker, A. Schmidt +14 more
2021Wellcome Open Research226 citations Open access
Semantic Scholar
Interleukin-6 receptor pathways in abdominal aortic aneurysm
S. Harrison, Andrew J. P. Smith, Gregory T. Jones, D. Swerdlow +23 more
2012European Heart Journal196 citations Open access
Semantic Scholar
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis
Jon White, R. Sofat, G. Hemani, T. Shah +47 more
2016The Lancet Diabetes and Endocrinology129 citations Open access
Semantic Scholar
Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm
S. Harrison, M. Holmes, S. Burgess, F. Asselbergs +19 more
2017JAMA cardiology126 citations Open access
Semantic Scholar
Secretory Phospholipase A2-IIA and Cardiovascular Disease
M. Holmes, T. Simon, H. Exeter, L. Folkersen +109 more
2013Journal of the American College of Cardiology105 citations Open access
Semantic Scholar
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
Sonia H. Shah, Albert Henry, C. Roselli, Hong-Huang Lin +142 more
2020Nature Communications74 citations Open access
Semantic Scholar
Gene-Centric Analysis Identifies Variants Associated With Interleukin-6 Levels and Shared Pathways With Other Inflammation Markers
T. Shah, D. Zabaneh, Tom R. Gaunt, D. Swerdlow +11 more
2013Circulation: Cardiovascular Genetics56 citations
Semantic Scholar
Pre-clinical assessment of SLN360, a novel siRNA targeting LPA, developed to address elevated lipoprotein (a) in cardiovascular disease.
David A. Rider, M. Eisermann, K. Löffler, M. Aleku +7 more
2022Atherosclerosis53 citations Open access
Semantic Scholar
Treatment and prevention of lipoprotein(a)-mediated cardiovascular disease: the emerging potential of RNA interference therapeutics
D. Swerdlow, David A. Rider, A. Yavari, Marie Wikström Lindholm +2 more
2021Cardiovascular Research51 citations Open access
Semantic Scholar
Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association With Glycemic Traits
C. Herder, Marja-Liisa Nuotio, Sonia H. Shah, S. Blankenberg +33 more
2014Diabetes51 citations Open access
Semantic Scholar
Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis: Mendelian Randomization Analysis
Sonia H. Shah, J. Casas, F. Drenos, J. Whittaker +19 more
2013Circulation: Cardiovascular Genetics48 citations
Semantic Scholar
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
A. Schmidt, M. Holmes, D. Preiss, D. Swerdlow +163 more
2018bioRxiv39 citations Open access
Semantic Scholar
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
Sonia H. Shah, J. Casas, Tom R. Gaunt, J. Cooper +16 more
2013European Heart Journal38 citations Open access
Semantic Scholar
Characteristics of exhaled particle production in healthy volunteers: possible implications for infectious disease transmission
F. Wurie, O. le Polain de Waroux, Matthew Brande, W. de Haan +5 more
2013F1000Research31 citations Open access
Semantic Scholar
Mendelian Randomization and Type 2 Diabetes
D. Swerdlow
2016Cardiovascular Drugs and Therapy24 citations Open access
Semantic Scholar
The genetics of coronary heart disease.
D. Swerdlow, M. Holmes, S. Harrison, S. Humphries
2012British Medical Bulletin23 citations
Semantic Scholar
The genomics of heart failure: design and rationale of the HERMES consortium
R. Lumbers, Sonia H. Shah, Hong-Huang Lin, T. Czuba +170 more
2021ESC Heart Failure21 citations Open access
Semantic Scholar
Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk
V. Tragante, F. Asselbergs, D. Swerdlow, T. Palmer +4 more
2016Human Genetics20 citations Open access
Semantic Scholar
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
A. Schmidt, D. Swerdlow, M. Holmes, R. Patel +2 more
201620 citations
Semantic Scholar
A dysglycaemic effect of statins in diabetes: relevance to clinical practice?
D. Swerdlow, N. Sattar
2014Diabetologia19 citations Open access
Semantic Scholar
Genetic Risk Factors and Mendelian Randomization in Cardiovascular Disease
D. Swerdlow, A. Hingorani, S. Humphries
2015Current Cardiology Reports13 citations
Semantic Scholar
Pharmacotherapy for children with elevated levels of lipoprotein(a): future directions
L. D. de Boer, A. Wiegman, D. Swerdlow, J. Kastelein +1 more
2022Expert Opinion on Pharmacotherapy9 citations Open access
Semantic Scholar
Genetics of CHD in 2016: Common and rare genetic variants and risk of CHD
D. Swerdlow, S. Humphries
2017Nature Reviews Cardiology9 citations
Semantic Scholar
Genetic insights into statin-associated diabetes risk
D. Swerdlow, D. Preiss
2016Current Opinion in Lipidology9 citations Open access
Semantic Scholar
Blood Lipids and Type 2 Diabetes Risk: Can Genetics Help Untangle the Web?
D. Swerdlow, N. Sattar
2015Diabetes9 citations
Semantic Scholar
Secretory Phospholipase A2-IIA and Cardiovascular Disease A Mendelian Randomization Study
M. Holmes, T. Simon, H. Exeter, L. Folkersen +109 more
20208 citations
Semantic Scholar
Detecting, predicting and modifying cardiovascular risk: new and developing strategies
T. Shah, D. Swerdlow
2010Expert Review of Cardiovascular Therapy7 citations
Semantic Scholar
Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure
Sonia H. Shah, Albert Henry, C. Roselli, Hong-Huang Lin +142 more
2019bioRxiv6 citations Open access
Semantic Scholar
Abstract 10469: Time Averaged Lipoprotein(a) Reduction With Sln360, a Novel Sirna Targeting Lp(a,) in Healthy Adults With Elevated Lp(a)
C. Rambaran, R. Wilson, D. Swerdlow, G. Campion +2 more
2022Circulation3 citations
Semantic Scholar
Complex disease genetics: present and future translational applications
M. Holmes, Sonia H. Shah, A. Angelakopoulou, T. Khan +4 more
2009Genome Medicine3 citations Open access
Semantic Scholar
Mendelian randomization for studying the effects of perturbing drug targets [ version 2 ; peer review : 2 approved ]
D. Gill, Marios K. Georgakis, V. Walker, A. F. Schmidt +14 more
20212 citations
Semantic Scholar
Abstract 14720: Pre-clinical Safety Assessment of SLN360, a Novel Short Interfering Ribonucleic Acid Targeting LPA
David A. Rider, D. Swerdlow, M. Eisermann, K. Loeffler +5 more
2020Circulation2 citations
Semantic Scholar
Mendelian randomization for studying the effects of perturbing drug targets [version 1; peer review: awaiting peer review]
D. Gill, Marios K. Georgakis, V. Walker, A. F. Schmidt +13 more
20211 citations
Semantic Scholar
Lipid Fractions and Contrasting Risks of Coronary Artery Disease and Diabetes: A Mendelian Randomization Study
Jon White, D. Swerdlow, D. Preiss, Fairhurst-Hunter +6 more
20161 citations
Semantic Scholar
Exhaled particle production data
F. Wurie, O. le Polain de Waroux, Matthew Brande, W. de Haan +5 more
20131 citations
Semantic Scholar
A report on the Genetics of Complex Diseases meeting of the British Atherosclerosis Society, Cambridge, UK, 17-18 September 2009.
M. Holmes, Sonia H. Shah, A. Angelakopoulou, T. Khan +4 more
2010Atherosclerosis1 citations
Semantic Scholar
Novel human neutralizing monoclonal antibodies against Pregnancy-Associated Plasma Protein A for the treatment of Autosomal Dominant Polycystic Kidney Disease.
Er-Ding Hu, M. Gardener, Xiao-Fang Wang, Gui-Zhen Luo +17 more
2026Kidney International0 citations Open access
Semantic Scholar
Association and risk prediction of 19 complex diseases with polygenic scores and socioeconomic status
F. Hagenbeek, Anne Richmond, Max Tamlander, K. Detrois +430 more
2026Communications Medicine0 citations Open access
Semantic Scholar
Novel Neutralizing Monoclonal Antibody (mAb) Against Pregnancy-Associated Plasma Protein A (PAPPA) for the Treatment of ADPKD
Erding Hu, M. Gardener, Guizhen Luo, Charles J. Kotzer +6 more
2025Journal of the American Society of Nephrology0 citations
Semantic Scholar
Edinburgh Research Explorer Plasma urate concentration and risk of coronary heart disease
Jon White, R. Sofat, G. Hemani, T. Shah +36 more
20180 citations
Semantic Scholar

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M. Holmes×26
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A. Hingorani×25
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M. Kumari×15
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F. Asselbergs×15
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J. Casas — researcher profile on SciRah

Sonia H. Shah×14

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M. Kivimaki×12

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N. Sattar — researcher profile on SciRah