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V. Walker · SciRah

Researcher profile · Semantic Scholar

V. Walker

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V. Walker — researcher profile on SciRah

h-index: 23
Works: 62
Citations: 2,805

Most-cited papers

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
Jie Zheng, V. Haberland, Denis A. Baird, V. Walker +30 more
2019bioRxiv679 citations Open access
Semantic Scholar
Mendelian randomization for studying the effects of perturbing drug targets
D. Gill, Marios K. Georgakis, V. Walker, A. Schmidt +14 more
2021Wellcome Open Research226 citations Open access
Semantic Scholar
Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales
R. Knight, V. Walker, S. Ip, Jonathan A. Cooper +25 more
2022Circulation211 citations Open access
Semantic Scholar
Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities
V. Walker, G. Davey Smith, N. Davies, Richard M. Martin
2017bioRxiv184 citations Open access
Semantic Scholar
Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource
A. Wood, R. Denholm, S. Hollings, Jennifer Cooper +136 more
2021British medical journal175 citations Open access
Semantic Scholar
Cardiometabolic Traits, Sepsis, and Severe COVID-19
Mark J. Ponsford, A. Gkatzionis, V. Walker, A. J. Grant +17 more
2020Circulation104 citations Open access
Semantic Scholar
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease
Jie Zheng, Yue-Miao Zhang, H. Rasheed, V. Walker +39 more
2020medRxiv95 citations Open access
Semantic Scholar
Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes
V. Walker, N. Davies, G. Hemani, Jie Zheng +4 more
2019Wellcome Open Research94 citations Open access
Semantic Scholar
Repurposing antihypertensive drugs for the prevention of Alzheimer’s disease: a Mendelian randomization study
V. Walker, Pat Kehoe, Richard M. Martin, N. Davies
2018bioRxiv86 citations Open access
Semantic Scholar
Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimer’s disease risk in the general population: a Mendelian randomisation study
Jie Zheng, Min Xu, V. Walker, Jinqiu Yuan +12 more
2022Diabetologia83 citations Open access
Semantic Scholar
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
Jie Zheng, V. Haberland, Denis A. Baird, V. Walker +30 more
2020Nature Genetics82 citations Open access
Semantic Scholar
Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England
W. Whiteley, S. Ip, Jonathan A. Cooper, T. Bolton +11 more
2022PLoS Medicine75 citations Open access
Semantic Scholar
COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records
J. Thygesen, Christopher Tomlinson, S. Hollings, M. Mizani +287 more
2022The Lancet Digital Health68 citations Open access
Semantic Scholar
Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression
Ruth E. Mitchell, A. Hartley, V. Walker, A. Gkatzionis +6 more
2022medRxiv66 citations Open access
Semantic Scholar
Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease
M. Levin, V. Zuber, V. Walker, D. Klarin +13 more
2021medRxiv54 citations Open access
Semantic Scholar
Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose: OpenSAFELY cohort study using linked electronic health records
E. Horne, W. Hulme, R. Keogh, T. Palmer +25 more
2022British medical journal53 citations Open access
Semantic Scholar
Phenotypic causal inference using genome-wide association study data: Mendelian randomization and beyond
V. Walker, Jie Zheng, T. Gaunt, G. D. Smith
2022Annual Review of Biomedical Data Science46 citations Open access
Semantic Scholar
How to estimate heritability: a guide for genetic epidemiologists
Ciarrah Barry, V. Walker, R. Cheesman, G. Davey Smith +2 more
2022International Journal of Epidemiology46 citations Open access
Semantic Scholar
Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: A multivariable Mendelian randomization study
Joshua A. Bell, T. Richardson, Qin Wang, E. Sanderson +9 more
2022The Lancet Regional Health - Europe35 citations Open access
Semantic Scholar
Comparative effectiveness of BNT162b2 versus mRNA-1273 covid-19 vaccine boosting in England: matched cohort study in OpenSAFELY-TPP
W. Hulme, E. Horne, E. Parker, R. Keogh +13 more
2023British medical journal33 citations Open access
Semantic Scholar
Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization study
Jie Zheng, Min Xu, Qian Yang, Chun-Yan Hu +18 more
2023EBioMedicine32 citations Open access
Semantic Scholar
Comparison with randomized controlled trials as a strategy for evaluating instruments in Mendelian randomization.
D. Gill, V. Walker, Richard M. Martin, N. Davies +1 more
2019International Journal of Epidemiology27 citations Open access
Semantic Scholar
Reading and conducting instrumental variable studies: guide, glossary, and checklist
V. Walker, E. Sanderson, M. Levin, Scott M Damraurer +2 more
2024British medical journal24 citations Open access
Semantic Scholar
Harmonising electronic health records for reproducible research: challenges, solutions and recommendations from a UK-wide COVID-19 research collaboration
H. Abbasizanjani, F. Torabi, S. Bedston, T. Bolton +16 more
2023BMC Medical Informatics and Decision Making23 citations Open access
Semantic Scholar
Comparison of Antihypertensive Drug Classes for Dementia Prevention
V. Walker, N. Davies, Richard M. Martin, Pat Kehoe
2019bioRxiv23 citations Open access
Semantic Scholar
Association between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease
M. Levin, D. Klarin, V. Walker, D. Gill +15 more
2021Arteriosclerosis, Thrombosis and Vascular Biology22 citations Open access
Semantic Scholar
Using Mendelian randomisation to identify opportunities for type 2 diabetes prevention by repurposing medications used for lipid management
Nikhil K. Khankari, Jacob M. Keaton, V. Walker, K. M. Lee +8 more
2022EBioMedicine19 citations Open access
Semantic Scholar
Genetically Predicted Blood Pressure and Risk of Atrial Fibrillation
M. Hyman, M. Levin, D. Gill, V. Walker +4 more
2021HYPERTENSION19 citations Open access
Semantic Scholar
Power calculator for instrumental variable analysis in pharmacoepidemiology
V. Walker, N. Davies, F. Windmeijer, S. Burgess +1 more
2016bioRxiv16 citations Open access
Semantic Scholar
Can commonly prescribed drugs be repurposed for the prevention or treatment of Alzheimer's and other neurodegenerative diseases? Protocol for an observational cohort study in the UK Clinical Practice Research Datalink
V. Walker, N. Davies, Tim Jones, Pat Kehoe +1 more
2016BMJ Open15 citations Open access
Semantic Scholar
Cardiometabolic traits, sepsis and severe covid-19 with respiratory failure: a Mendelian randomization investigation
P. Mark, A. Gkatzionis, V. Walker, A. Grant +17 more
2020medRxiv12 citations Open access
Semantic Scholar
Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes
V. Walker, Marijana Vujković, A. Carter, N. Davies +6 more
2022Diabetologia10 citations Open access
Semantic Scholar
What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England? A trend analysis in the Clinical Practice Research Datalink
V. Walker, N. Davies, Pat Kehoe, Richard M. Martin
2018Alzheimer's Research & Therapy10 citations Open access
Semantic Scholar
Association of COVID-19 with arterial and venous vascular diseases: a population-wide cohort study of 48 million adults in England and Wales
R. Knight, V. Walker, S. Ip, Jonathan A. Cooper +23 more
2021medRxiv9 citations Open access
Semantic Scholar
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors
G. Shakt, Noah L. Tsao, M. Levin, V. Walker +6 more
2024Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease8 citations Open access
Semantic Scholar
The consequences of adjustment, correction and selection in genome-wide association studies used for two-sample Mendelian randomization
V. Walker, S. Harrison, A. Carter, D. Gill +2 more
2020medRxiv8 citations Open access
Semantic Scholar
Dominant role of abdominal adiposity in circulating lipoprotein, lipid, and metabolite levels in UK Biobank: Mendelian randomization study
Joshua A. Bell, T. Richardson, Qin Wang, E. Sanderson +9 more
2021medRxiv7 citations Open access
Semantic Scholar
Mendelian randomization applied to pharmaceutical use: the case of metformin and lung cancer
J. Yarmolinsky, C. Bull, V. Walker, A. Nounu +1 more
2020International Journal of Epidemiology7 citations Open access
Semantic Scholar
Little genomic support for Cyclophilin A-matrix metalloproteinase-9 pathway as a therapeutic target for cognitive impairment in APOE4 carriers
E. Anderson, Dylan M. Williams, V. Walker, N. Davies
2021Scientific Reports6 citations Open access
Semantic Scholar
Genetic effect modification of cis-acting C-reactive protein variants in cardiometabolic disease status
Jie Zheng, Haotian Tang, M. Lyon, N. Davies +7 more
2021bioRxiv3 citations Open access
Semantic Scholar
Letter regarding, “Association between the use of aspirin and risk of lung cancer: results from pooled cohorts and Mendelian randomization analyses”
A. Nounu, V. Walker, R. Richmond
2021Journal of Cancer Research and Clinical Oncology3 citations Open access
Semantic Scholar
Diabetes following SARS-CoV-2 infection: Incidence, persistence, and implications of COVID-19 vaccination. A cohort study of fifteen million people.
K. Taylor, S. Eastwood, V. Walker, G. Cézard +26 more
2023medRxiv2 citations Open access
Semantic Scholar
Mendelian randomization for studying the effects of perturbing drug targets [ version 2 ; peer review : 2 approved ]
D. Gill, Marios K. Georgakis, V. Walker, A. F. Schmidt +14 more
20212 citations
Semantic Scholar
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease
Jie Zheng, Yue-Miao Zhang, H. Rasheed, V. Walker +39 more
20212 citations
Semantic Scholar
Can treatments for hypertension be repurposed for the treatment of dementia?
V. Walker, N. Davies, Pat Kehoe, R. Martin
2018Revue d'épidémiologie et de santé publique2 citations
Semantic Scholar
CPRD codes: neurodegenerative diseases and commonly prescribed drugs
V. Walker, Richard M Martin, Pat Kehoe, N. Davies
20172 citations
Semantic Scholar
Abstract 361: Bidirectional Mendelian Randomization Investigating The Causal Relationship Between Major Depressive Disorder And Peripheral Artery Disease
G. Shakt, Noah L. Tsao, M. Levin, V. Walker +6 more
2022Arteriosclerosis, Thrombosis and Vascular Biology1 citations
Semantic Scholar
Pharmacoepidemiology in pregnancy: analysis protocol for an observational cohort study in the UK Clinical Practice Research Datalink
Ciarrah Barry, C. Burden, N. Davies, V. Walker
2022Wellcome Open Research1 citations Open access
Semantic Scholar
Mendelian randomization for studying the effects of perturbing drug targets [version 1; peer review: awaiting peer review]
D. Gill, Marios K. Georgakis, V. Walker, A. F. Schmidt +13 more
20211 citations
Semantic Scholar
How to estimate heritability, a guide for epidemiologists
Ciarrah Barry, V. Walker, R. Cheesman, G. Smith +2 more
20211 citations
Semantic Scholar

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