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M. Meuth · SciRah

Researcher profile · Semantic Scholar

M. Meuth

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M. Meuth — researcher profile on SciRah

h-index: 49
Works: 157
Citations: 13K

Most-cited papers

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
Helen E. Bryant, N. Schultz, H. Thomas, Kayan M. Parker +6 more
2005Nature4,765 citations Open access
Semantic Scholar
Mutator phenotypes in human colorectal carcinoma cell lines.
N. Bhattacharyya, A. Skandalis, A. Ganesh, J. Groden +1 more
1994Proceedings of the National Academy of Sciences of the United States of America436 citations Open access
Semantic Scholar
Distinct microRNA alterations characterize high and low grade bladder cancer
J. Catto, S. Miah, H. Owen, Helen E. Bryant +11 more
2009Cancer Research329 citations Open access
Semantic Scholar
Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma.
J. Catto, A. Azzouzi, Ishtiaq Rehman, K. Feeley +7 more
2005Journal of Clinical Oncology311 citations Open access
Semantic Scholar
Different Roles for Nonhomologous End Joining and Homologous Recombination following Replication Arrest in Mammalian Cells
Cecilia Lundin, K. Erixon, C. Arnaudeau, N. Schultz +3 more
2002Molecular and Cellular Biology264 citations Open access
Semantic Scholar
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
Helen E. Bryant, N. Schultz, H. Thomas, Kayan M. Parker +6 more
2007Nature250 citations
Semantic Scholar
Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress.
R. Rodríguez, M. Meuth
2005Molecular Biology of the Cell186 citations Open access
Semantic Scholar
Promoter Hypermethylation Identifies Progression Risk in Bladder Cancer
D. Yates, Ishtiaq Rehman, M. Abbod, M. Meuth +4 more
2007Clinical Cancer Research178 citations Open access
Semantic Scholar
Association of a common variant of the CASP8 gene with reduced risk of breast cancer.
G. Macpherson, C. Healey, M. Teare, S. Balasubramanian +6 more
2004Journal of the National Cancer Institute165 citations Open access
Semantic Scholar
Molecular Detection of Localized Prostate Cancer Using Quantitative Methylation-Specific PCR on Urinary Cells Obtained Following Prostate Massage
M. Rouprêt, V. Hupertan, D. Yates, J. Catto +11 more
2007Clinical Cancer Research155 citations Open access
Semantic Scholar
Distinct patterns of microsatellite instability are seen in tumours of the urinary tract
J. Catto, A. Azzouzi, Najla Amira, Ishtiaq Rehman +7 more
2003Oncogene143 citations Open access
Semantic Scholar
Enhanced H2AX Phosphorylation, DNA Replication Fork Arrest, and Cell Death in the Absence of Chk1
M. Gagou, Pedro Zuazua-Villar, M. Meuth
2010Molecular Biology of the Cell142 citations Open access
Semantic Scholar
A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer.
S. Rafii, Paul O'Regan, G. Xinarianos, Iman A. F. Azmy +5 more
2002Human Molecular Genetics140 citations
Semantic Scholar
FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours.
J. V. van Oers, E. Zwarthoff, Ishtiaq Rehman, A. Azzouzi +4 more
2009European Urology135 citations
Semantic Scholar
ATR and Chk1 Suppress a Caspase-3–Dependent Apoptotic Response Following DNA Replication Stress
K. Myers, M. Gagou, Pedro Zuazua-Villar, R. Rodríguez +1 more
2009PLoS Genetics134 citations Open access
Semantic Scholar
Proteomic analysis of voided urine after prostatic massage from patients with prostate cancer: a pilot study.
Ishtiaq Rehman, A. Azzouzi, J. Catto, S. Allen +4 more
2004Urology113 citations
Semantic Scholar
The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
Ali Z. Al-Minawi, Yin-Fai Lee, Daniel Håkansson, F. Johansson +8 more
2009Nucleic Acids Research104 citations Open access
Semantic Scholar
Methylational urinalysis: a prospective study of bladder cancer patients and age stratified benign controls
D. Yates, Ishtiaq Rehman, M. Meuth, S. Cross +2 more
2006Oncogene98 citations Open access
Semantic Scholar
Molecular analysis of mutations in mutator colorectal carcinoma cell lines.
Nitai P. Bhattacharyya, Anil Ganesh, G. Phear, Burt Richards +2 more
1995Human Molecular Genetics95 citations Open access
Semantic Scholar
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
Burt Richards, Hong Zhang, G. Phear, M. Meuth
1997Science92 citations
Semantic Scholar
ATM is required for the cellular response to thymidine induced replication fork stress.
E. Bolderson, Jennifer Scorah, T. Helleday, C. Smythe +1 more
2004Human Molecular Genetics91 citations
Semantic Scholar
Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability
J. Catto, G. Xinarianos, J. Burton, M. Meuth +1 more
2003International Journal of Cancer90 citations Open access
Semantic Scholar
Human Embryonic Stem Cells Fail to Activate CHK1 and Commit to Apoptosis in Response to DNA Replication Stress
Joëlle A. Desmarais, M. Hoffmann, G. Bingham, Mary E. Gagou +2 more
2012Stem Cells88 citations
Semantic Scholar
Promoter hypermethylation in circulating blood cells identifies prostate cancer progression
M. Rouprêt, V. Hupertan, J. Catto, D. Yates +6 more
2008International Journal of Cancer86 citations Open access
Semantic Scholar
Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines.
A. Mohindra, L. Hays, E. Phillips, B. Preston +2 more
2002Human Molecular Genetics80 citations
Semantic Scholar
Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma
D. Dhawan, F. Hamdy, Ishtiaq Rehman, J. Patterson +5 more
2006Journal of Pathology74 citations
Semantic Scholar
HDAC inhibitor confers radiosensitivity to prostate stem-like cells
F. Frame, D. Pellacani, A. Collins, M. Simms +5 more
2013British Journal of Cancer69 citations Open access
Semantic Scholar
Microsatellite instability as indicator of MSH2 gene mutation in patients with upper urinary tract transitional cell carcinoma
M. Rouprêt, James W. F. Catto, F. Coulet, A. Azzouzi +9 more
2004Journal of Medical Genetics69 citations Open access
Semantic Scholar
A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.
Q. Wen, Jennifer Scorah, G. Phear, G. Rodgers +2 more
2008Molecular Biology of the Cell68 citations Open access
Semantic Scholar
Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks
T. George, Q. Wen, Richard Griffiths, A. Ganesh +2 more
2009Nucleic Acids Research65 citations Open access
Semantic Scholar
Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance.
J. Catto, A. Hartmann, R. Stoehr, E. Bolderson +4 more
2006Journal of Urology63 citations
Semantic Scholar
A comparison of the performance of microsatellite and methylation urine analysis for predicting the recurrence of urothelial cell carcinoma, and definition of a set of markers by Bayesian network analysis
M. Rouprêt, V. Hupertan, D. Yates, E. Compérat +9 more
2008BJU International58 citations
Semantic Scholar
EMBRYONIC STEM CELLS / INDUCED PLURIPOTENT STEM CELLS Deficient DNA Damage Response and Cell Cycle Checkpoints Lead to Accumulation of Point Mutations in Human Embryonic Stem Cells
Nevila Hyka-Nouspikel, Joëlle A. Desmarais, P. Gokhale, Mark Jones +3 more
201249 citations
Semantic Scholar
Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3.
John M. Hinz, T. Helleday, M. Meuth
2003Carcinogenesis46 citations
Semantic Scholar
Microsatellite instability and the PTEN1 gene mutation in a subset of early onset gliomas carrying germline mutation or promoter methylation of the hMLH1 gene
M. Kanamori, H. Kon, T. Nobukuni, Sachio Nomura +7 more
2000Oncogene46 citations Open access
Semantic Scholar
Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress
M. Gagou, A. Ganesh, G. Phear, Darren Robinson +3 more
2014OncoTarget44 citations Open access
Semantic Scholar
Suppression of apoptosis by PIF1 helicase in human tumor cells.
M. Gagou, A. Ganesh, Ruth Thompson, G. Phear +2 more
2011Cancer Research41 citations Open access
Semantic Scholar
Apoptosis induced by replication inhibitors in Chk1-depleted cells is dependent upon the helicase cofactor Cdc45
R. Rodríguez, M. Gagou, M. Meuth
2008Cell Death and Differentiation41 citations
Semantic Scholar
Thymidine Selectively Enhances Growth Suppressive Effects of Camptothecin/Irinotecan in MSI+ Cells and Tumors Containing a Mutation of MRE11
R. Rodríguez, L. Hansen, G. Phear, Jennifer Scorah +4 more
2008Clinical Cancer Research41 citations
Semantic Scholar
DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B
Pedro Zuazua-Villar, R. Rodríguez, Mary E. Gagou, P. Eyers +1 more
2014Cell Death and Disease38 citations Open access
Semantic Scholar
Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress
Joëlle A. Desmarais, C. Unger, I. Damjanov, M. Meuth +1 more
2016Stem cell research & therapeutics36 citations Open access
Semantic Scholar
Chk1 suppressed cell death
M. Meuth
2010Cell Division35 citations Open access
Semantic Scholar
Treatment with the Chk1 inhibitor Gö6976 enhances cisplatin cytotoxicity in SCLC cells.
Ruth Thompson, M. Meuth, P. Woll, Yong M. Zhu +1 more
2011International Journal of Oncology30 citations Open access
Semantic Scholar
DNA sequence analysis of gamma radiation—induced deletions and insertions at the APRT locus of hamster cells
C. Miles, G. Sargent, G. Phear, M. Meuth
2006Molecular Carcinogenesis29 citations
Semantic Scholar
Resistance to cytosine arabinoside in acute leukemia: the significance of mutations in CTP synthetase.
J. Whelan, T. Smith, G. Phear, A. Rohatiner +2 more
1994Leukemia28 citations
Semantic Scholar
Genetic instability and transitional cell carcinoma of the bladder
J. Catto, M. Meuth, F. Hamdy
2004BJU International27 citations
Semantic Scholar
Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells
Pedro Zuazua-Villar, A. Ganesh, G. Phear, M. Gagou +1 more
2015Nucleic Acids Research23 citations Open access
Semantic Scholar
A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks.
A. Mohindra, E. Bolderson, J. Stone, M. Wells +2 more
2003Human Molecular Genetics20 citations Open access
Semantic Scholar
MSH3 deficiency is not sufficient for a mutator phenotype in Chinese hamster ovary cells.
John M. Hinz, M. Meuth
1999Carcinogenesis19 citations
Semantic Scholar
A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility.
S. Rafii, A. Lindblom, M. Reed, M. Meuth +1 more
2003Human Molecular Genetics17 citations
Semantic Scholar

Frequent co-authors

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J. Catto×14
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J. Catto — researcher profile on SciRah
F. Hamdy×14
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F. Hamdy — researcher profile on SciRah
Ishtiaq Rehman×11
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Ishtiaq Rehman — researcher profile on SciRah
T. Helleday×9
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T. Helleday — researcher profile on SciRah

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G. Phear — researcher profile on SciRah

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S. Cross — researcher profile on SciRah

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M. Gagou — researcher profile on SciRah

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A. Ganesh — researcher profile on SciRah

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A. Azzouzi — researcher profile on SciRah

R. Rodríguez×5

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R. Rodríguez — researcher profile on SciRah

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D. Yates — researcher profile on SciRah

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A. Cox — researcher profile on SciRah