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N. Schultz · SciRah

Researcher profile · Semantic Scholar

N. Schultz

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N. Schultz — researcher profile on SciRah

h-index: 31
Works: 63
Citations: 11K

Most-cited papers

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
Helen E. Bryant, N. Schultz, H. Thomas, Kayan M. Parker +6 more
2005Nature4,765 citations Open access
Semantic Scholar
Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
E. Petermann, M. L. Orta, N. Issaeva, N. Schultz +1 more
2010Molecules and Cells852 citations Open access
Semantic Scholar
PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination
Helen E. Bryant, E. Petermann, N. Schultz, A. Jemth +6 more
2009EMBO Journal633 citations Open access
Semantic Scholar
Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity
E. Berglund, J. Maaskola, N. Schultz, S. Friedrich +14 more
2018Nature Communications504 citations Open access
Semantic Scholar
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
H. Gad, T. Koolmeister, A. Jemth, Saeed Eshtad +53 more
2014Nature491 citations
Semantic Scholar
Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks
N. Saleh-Gohari, Helen E. Bryant, N. Schultz, Kayan M. Parker +2 more
2005Molecular and Cellular Biology345 citations Open access
Semantic Scholar
Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination.
N. Schultz, E. Lopez, N. Saleh-Gohari, T. Helleday
2003Nucleic Acids Research323 citations Open access
Semantic Scholar
Spatially resolved clonal copy number alterations in benign and malignant tissue
A. Erickson, Meng-Xiao He, E. Berglund, M. Marklund +27 more
2022Nature284 citations Open access
Semantic Scholar
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer
M. Asim, F. Tarish, H. Zecchini, K. Sanjiv +26 more
2017Nature Communications271 citations Open access
Semantic Scholar
Different Roles for Nonhomologous End Joining and Homologous Recombination following Replication Arrest in Mammalian Cells
Cecilia Lundin, K. Erixon, C. Arnaudeau, N. Schultz +3 more
2002Molecular and Cellular Biology264 citations Open access
Semantic Scholar
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
Helen E. Bryant, N. Schultz, H. Thomas, Kayan M. Parker +6 more
2007Nature250 citations
Semantic Scholar
Molecular and Cellular Pathobiology Cancer Research Poly ( ADP-Ribose ) Polymerase Is Hyperactivated in Homologous Recombination – Defective Cells
Ponnari Gottipati, B. Vischioni, N. Schultz, J. Solomons +6 more
2010224 citations
Semantic Scholar
Poly(ADP-ribose) Polymerase (PARP-1) in Homologous Recombination and as a Target for Cancer Therapy
T. Helleday, Helen E. Bryant, N. Schultz
2005Cell Cycle195 citations Open access
Semantic Scholar
Kinetics and dose-response of residual 53BP1/γ-H2AX foci: Co-localization, relationship with DSB repair and clonogenic survival
E. Marková, N. Schultz, I. Belyaev
2007International Journal of Radiation Biology193 citations
Semantic Scholar
RAD51 is involved in repair of damage associated with DNA replication in mammalian cells.
Cecilia Lundin, N. Schultz, C. Arnaudeau, A. Mohindra +2 more
2003Journal of Molecular Biology125 citations
Semantic Scholar
Genome-wide spatial expression profiling in formalin-fixed tissues
Eva Gracia Villacampa, L. Larsson, R. Mirzazadeh, L. Kvastad +13 more
2021Cell Genomics118 citations Open access
Semantic Scholar
Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro.
P. Mellroth, J. Karlsson, J. Håkansson, N. Schultz +2 more
2005Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
Ali Z. Al-Minawi, Yin-Fai Lee, Daniel Håkansson, F. Johansson +8 more
2009Nucleic Acids Research104 citations Open access
Semantic Scholar
Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities
K. Sanjiv, A. Hagenkort, J. M. Calderón-Montaño, T. Koolmeister +11 more
2015Cell Reports91 citations Open access
Semantic Scholar
Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.
P. Groth, Simon Ausländer, M. Majumder, N. Schultz +3 more
2010Journal of Molecular Biology90 citations
Semantic Scholar
Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities
K. Sanjiv, A. Hagenkort, J. M. Calderón-Montaño, T. Koolmeister +11 more
2016Cell Reports82 citations Open access
Semantic Scholar
Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair
F. Tarish, N. Schultz, A. Tanoglidi, H. Hamberg +5 more
2015Science Translational Medicine82 citations
Semantic Scholar
The detection and evaluation of aneugenic chemicals.
J. Parry, E. Parry, R. Boumer, A. Doherty +38 more
1996Mutation research80 citations
Semantic Scholar
Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples
R. Mirzazadeh, Žaneta Andrusivová, L. Larsson, P. T. Newton +14 more
2022bioRxiv66 citations Open access
Semantic Scholar
Castration Therapy Results in Decreased Ku70 Levels in Prostate Cancer
Firas L. T. Al-Ubaidi, N. Schultz, O. Loseva, L. Egevad +2 more
2013Clinical Cancer Research66 citations Open access
Semantic Scholar
Identification of glycine N‐acyltransferase‐like 2 (GLYATL2) as a transferase that produces N‐acyl glycines in humans
Dominik P. Waluk, N. Schultz, M. Hunt
2010The FASEB Journal63 citations
Semantic Scholar
p53 protects from replication-associated DNA double-strand breaks in mammalian cells
A. Kumari, N. Schultz, T. Helleday
2004Oncogene60 citations
Semantic Scholar
CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
Cecilia E. Ström, O. Mortusewicz, D. Finch, Jason L. Parsons +6 more
2011DNA Repair41 citations
Semantic Scholar
Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer susceptibility.
A. Lindh, S. Rafii, N. Schultz, A. Cox +1 more
2006Human Molecular Genetics39 citations Open access
Semantic Scholar
Genotoxicity of alcohol is linked to DNA replication-associated damage and homologous recombination repair.
Natalia Kotova, D. Vare, N. Schultz, Dobroslawa Gradecka Meesters +4 more
2013Carcinogenesis37 citations
Semantic Scholar
RAD51C (RAD51L2) is involved in maintaining centrosome number in mitosis
A. Lindh, N. Schultz, N. Saleh-Gohari, T. Helleday
2007Cytogenetic and Genome Research33 citations
Semantic Scholar
Castration therapy of prostate cancer results in downregulation of HIF-1α levels.
Firas L. T. Al-Ubaidi, N. Schultz, L. Egevad, T. Granfors +1 more
2012International Journal of Radiation Oncology, Biology, Physics28 citations
Semantic Scholar
CHK1 activity is required for continuous replication fork elongation but not stabilization of post-replicative gaps after UV irradiation
Ingegerd Elvers, A. Hagenkort, F. Johansson, T. Djureinovic +5 more
2012Nucleic Acids Research24 citations Open access
Semantic Scholar
Abstract 105: MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells
K. Sanjiv, H. Gad, S. G. Rudd, O. Mortusewicz +23 more
2019Tumor Biology20 citations Open access
Semantic Scholar
Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clones
M. Marklund, N. Schultz, S. Friedrich, E. Berglund +9 more
2022Nature Communications16 citations Open access
Semantic Scholar
High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue
Ning Zhang, L. Harbers, Michele Simonetti, Constantin Diekmann +24 more
2021bioRxiv14 citations Open access
Semantic Scholar
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
N. Nicolay, R. Carter, S. Hatch, N. Schultz +4 more
2012Carcinogenesis12 citations Open access
Semantic Scholar
Transcription Inhibition by DRB Potentiates Recombinational Repair of UV Lesions in Mammalian Cells
I. Stoimenov, N. Schultz, Ponnari Gottipati, T. Helleday
2011PLoS ONE11 citations Open access
Semantic Scholar
Abstract PR016: The spatial landscape of clonal somatic mutations in benign and malignant tissue
A. Erickson, E. Berglund, Meng-Xiao He, M. Marklund +25 more
2022Cancer Research10 citations
Semantic Scholar
Correction: Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
H. Gad, T. Koolmeister, A. Jemth, Saeed Eshtad +52 more
2017Nature8 citations Open access
Semantic Scholar
CHK 1 activity is required for continuous replication fork elongation but not stabilization of post-replicative gaps after UV irradiation
Ingegerd Elvers, A. Hagenkort, F. Johansson, T. Djureinovic +5 more
20127 citations
Semantic Scholar
Transcription inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) causes DNA damage and triggers homologous recombination repair in mammalian cells.
I. Stoimenov, Ponnari Gottipati, N. Schultz, T. Helleday
2011Mutation research4 citations
Semantic Scholar
The potential radiosensitization target PFKFB3 is related to response to radiotherapy in SweBCG91RT: a randomized clinical trial with long-term follow-up
Moa Egelberg, Tommaso de Marchi, N. Schultz, Lena Tran +5 more
2025BMC Cancer2 citations Open access
Semantic Scholar
Human glycine N-acyltransferase-like 1 is involved in the production of glycine conjugated fatty acids
Dominik P. Waluk, N. Schultz, M. Hunt
20092 citations
Semantic Scholar
P047 Castration promotes radiosensitivity by direct regulation of DNA repair in prostate cancer
Firas L. T. Al-Ubaidi, N. Schultz, H. Hamberg, T. Granfors +1 more
20141 citations
Semantic Scholar
Abstract A051: The spatial landscape of clonal somatic copy number alterations in benign and malignant prostate epithelia
A. Erickson, Meng-Xiao He, E. Berglund, M. Marklund +27 more
2023Cancer Research0 citations
Semantic Scholar
MP45-14 THE SPATIAL LANDSCAPE OF CLONAL SOMATIC MUTATIONS IN BENIGN AND MALIGNANT PROSTATE EPITHELIA
A. Erickson, E. Berglund, Meng-Xiao He, M. Marklund +25 more
2022Journal of Urology0 citations
Semantic Scholar
Abstract 2171: The spatial landscape of clonal somatic mutations in benign and malignant tissue
Andrew Erickson, E. Berglund, Meng-Xiao He, M. Marklund +25 more
2022Cancer Research0 citations
Semantic Scholar
Editor's Note: Castration Therapy Results in Decreased Ku70 Levels in Prostate Cancer
Firas L. T. Al-Ubaidi, N. Schultz, O. Loseva, L. Egevad +2 more
2021Clinical Cancer Research0 citations Open access
Semantic Scholar
A Transcriptome Atlas of a Cross Section of a Multifocal Prostate Cancer
E. Berglund, N. Schultz, M. Marklund, Ludvig Bergensthråhle +8 more
20200 citations
Semantic Scholar

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