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M. Hoffmann · SciRah

Researcher profile · Semantic Scholar

M. Hoffmann

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M. Hoffmann — researcher profile on SciRah

h-index: 32
Works: 107
Citations: 2,819

Most-cited papers

Downregulation of several fibulin genes in prostate cancer
Agnes Wlazlinski, R. Engers, M. Hoffmann, C. Hader +3 more
2007The Prostate115 citations
Semantic Scholar
Human Embryonic Stem Cells Fail to Activate CHK1 and Commit to Apoptosis in Response to DNA Replication Stress
Joëlle A. Desmarais, M. Hoffmann, G. Bingham, Mary E. Gagou +2 more
2012Stem Cells88 citations
Semantic Scholar
Epigenetic mechanisms in the biology of prostate cancer.
W. Schulz, M. Hoffmann
2009Seminars in Cancer Biology81 citations
Semantic Scholar
The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells
Judith Heubach, Juliana Monsior, R. Deenen, G. Niegisch +4 more
2015Molecular Cancer79 citations Open access
Semantic Scholar
Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine
M. Isono, M. Hoffmann, Maria Pinkerneil, A. Sato +4 more
2017Journal of experimental & clinical cancer research : CR73 citations Open access
Semantic Scholar
Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
W. Schulz, A. Alexa, V. Jung, C. Hader +10 more
2007Molecular Cancer64 citations Open access
Semantic Scholar
Combined inhibition of BET proteins and class I HDACs synergistically induces apoptosis in urothelial carcinoma cell lines
A. Hölscher, W. Schulz, Maria Pinkerneil, G. Niegisch +1 more
2018Clinical Epigenetics63 citations Open access
Semantic Scholar
Effects of novel HDAC inhibitors on urothelial carcinoma cells
Aline Kaletsch, Maria Pinkerneil, M. Hoffmann, A. A. Jaguva Vasudevan +10 more
2018Clinical Epigenetics59 citations Open access
Semantic Scholar
Urothelial Carcinoma
W. Schulz, M. Hoffmann
2018Methods in Molecular Biology59 citations Open access
Semantic Scholar
Inhibition of Class I Histone Deacetylases 1 and 2 Promotes Urothelial Carcinoma Cell Death by Various Mechanisms
Maria Pinkerneil, M. Hoffmann, R. Deenen, K. Köhrer +3 more
2016Molecular Cancer Therapeutics56 citations Open access
Semantic Scholar
Expression profile of the polycomb group protein enhancer of Zeste homologue 2 and its prognostic relevance in renal cell carcinoma.
S. Hinz, S. Weikert, A. Magheli, M. Hoffmann +3 more
2009Journal of Urology54 citations
Semantic Scholar
Evaluation of the Therapeutic Potential of the Novel Isotype Specific HDAC Inhibitor 4SC-202 in Urothelial Carcinoma Cell Lines
Maria Pinkerneil, M. Hoffmann, H. Kohlhof, W. Schulz +1 more
2016Targeted oncology52 citations Open access
Semantic Scholar
Characterization of the Olfactory Receptor OR10H1 in Human Urinary Bladder Cancer
Lea Weber, W. Schulz, S. Philippou, Josephine Eckardt +6 more
2018Frontiers in Physiology51 citations Open access
Semantic Scholar
Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma
J. Droop, T. Szarvas, W. Schulz, C. Niedworok +3 more
2017PLoS ONE47 citations Open access
Semantic Scholar
Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer.
M. Hornstein, M. Hoffmann, A. Alexa, Masanori Yamanaka +4 more
2008Cancer Genomics & Proteomics47 citations
Semantic Scholar
Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex.
David Schlütermann, M. Skowron, N. Berleth, P. Böhler +8 more
2017Urologic oncology46 citations Open access
Semantic Scholar
The New Immortalized Uroepithelial Cell Line HBLAK Contains Defined Genetic Aberrations Typical of Early Stage Urothelial Tumors
M. Hoffmann, E. Koutsogiannouli, M. Skowron, Maria Pinkerneil +5 more
2016Bladder Cancer44 citations Open access
Semantic Scholar
Limited efficacy of specific HDAC6 inhibition in urothelial cancer cells
L. Rosik, G. Niegisch, U. Fischer, M. Jung +2 more
2014Cancer Biology & Therapy41 citations Open access
Semantic Scholar
Expression of the polycomb group protein EZH2 and its relation to outcome in patients with urothelial carcinoma of the bladder
S. Hinz, C. Kempkensteffen, F. Christoph, M. Hoffmann +5 more
2008Journal of Cancer Research and Clinical Oncology39 citations Open access
Semantic Scholar
Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1
Chen-Yin Wang, A. Hamacher, Patrick Petzsch, K. Köhrer +4 more
2020Cancers38 citations Open access
Semantic Scholar
Multifaceted Mechanisms of Cisplatin Resistance in Long-Term Treated Urothelial Carcinoma Cell Lines
M. Skowron, Margarita Melnikova, J. V. van Roermund, A. Romano +5 more
2018International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma
N. Klümper, D. Ralser, Romina Zarbl, K. Schlack +18 more
2021Journal for ImmunoTherapy of Cancer36 citations Open access
Semantic Scholar
Canonical Notch signalling is inactive in urothelial carcinoma
A. Greife, S. Jankowiak, Jochen Steinbring, P. Nikpour +3 more
2014BMC Cancer35 citations Open access
Semantic Scholar
Altered expression of LINC-ROR in cancer cell lines and tissues
Majdaddin Rezaei, M. Emadi-Baygi, M. Hoffmann, W. Schulz +1 more
2016Tumor Biology34 citations
Semantic Scholar
The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells*
S. Nakhaei-Rad, H. Nakhaeizadeh, S. Götze, C. Kordes +8 more
2016Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Oxidative stress and LINE-1 reactivation in bladder cancer are epigenetically linked through active chromatin formation.
P. Whongsiri, Chaowat Pimratana, Udomsak Wijitsettakul, A. Sanpavat +5 more
2019Free Radical Biology & Medicine32 citations
Semantic Scholar
Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment
M. Lehmann, M. Hoffmann, Annemarie Koch, Scott M. Ulrich +2 more
2014Journal of experimental & clinical cancer research : CR31 citations Open access
Semantic Scholar
Epigenetic Priming of Bladder Cancer Cells With Decitabine Increases Cytotoxicity of Human EGFR and CD44v6 CAR Engineered T-Cells
C. Grunewald, C. Haist, C. König, Patrick Petzsch +8 more
2021Frontiers in Immunology30 citations Open access
Semantic Scholar
LINE-1 ORF1 Protein Is Up-regulated by Reactive Oxygen Species and Associated with Bladder Urothelial Carcinoma Progression.
P. Whongsiri, Chaowat Pimratana, Udomsak Wijitsettakul, D. Jindatip +5 more
2018Cancer Genomics & Proteomics29 citations Open access
Semantic Scholar
Transcription Factor Networks in Embryonic Stem Cells and Testicular Cancer and the Definition of Epigenetics
W. Schulz, M. Hoffmann
2007Epigenetics29 citations Open access
Semantic Scholar
Alterations of Chromatin Regulators in the Pathogenesis of Urinary Bladder Urothelial Carcinoma
M. Hoffmann, W. Schulz
2021Cancers28 citations Open access
Semantic Scholar
Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines
M. Skowron, G. Niegisch, G. Fritz, Tanja Arent +5 more
2015Journal of experimental & clinical cancer research : CR28 citations Open access
Semantic Scholar
Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma
M. Sassenberg, J. Droop, W. Schulz, D. Dietrich +5 more
2019BMC Cancer27 citations Open access
Semantic Scholar
Applying the chicken embryo chorioallantoic membrane assay to study treatment approaches in urothelial carcinoma.
M. Skowron, A. Sathe, A. Romano, M. Hoffmann +5 more
2017Urologic oncology27 citations
Semantic Scholar
A new and reliable culture system for superficial low-grade urothelial carcinoma of the bladder
H. Seifert, A. Meyer, M. Cronauer, J. Hatina +5 more
2007World journal of urology27 citations Open access
Semantic Scholar
HDACs and HDAC Inhibitors in Urothelial Carcinoma - Perspectives for an Antineoplastic Treatment.
Maria Pinkerneil, M. Hoffmann, W. Schulz, G. Niegisch
2017Current Medicinal Chemistry26 citations
Semantic Scholar
Contingencies of UTX/KDM6A Action in Urothelial Carcinoma
A. Lang, M. Yılmaz, C. Hader, Sammy Murday +9 more
2019Cancers25 citations Open access
Semantic Scholar
Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells
E. Koutsogiannouli, Nicholas Wagner, C. Hader, Maria Pinkerneil +2 more
2017International Journal of Molecular Sciences25 citations Open access
Semantic Scholar
Truncated Isoforms of lncRNA ANRIL Are Overexpressed in Bladder Cancer, But Do Not Contribute to Repression of INK4 Tumor Suppressors
M. Hoffmann, J. Dehn, J. Droop, G. Niegisch +3 more
2015Non-Coding RNA24 citations Open access
Semantic Scholar
Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells
M. Hoffmann, Sarah Meneceur, K. Hommel, W. Schulz +1 more
2021Genes21 citations Open access
Semantic Scholar
Prodigiosin Sensitizes Sensitive and Resistant Urothelial Carcinoma Cells to Cisplatin Treatment
Lena Berning, David Schlütermann, Annabelle Friedrich, N. Berleth +10 more
2021Molecules21 citations Open access
Semantic Scholar
Engineering a single-chain variable fragment of cetuximab for CAR T-cell therapy against head and neck squamous cell carcinomas.
C. Haist, Z. Poschinski, A. Bister, M. Hoffmann +6 more
2022Oral Oncology20 citations
Semantic Scholar
Distinct mechanisms contribute to acquired cisplatin resistance of urothelial carcinoma cells
A. Höhn, Katharina Krüger, M. Skowron, S. Bormann +5 more
2016OncoTarget20 citations Open access
Semantic Scholar
Evaluation of HER2 expression in urothelial carcinoma cells as a biomarker for circulating tumor cells
A. Nini, M. Hoffmann, R. Lampignano, Robert Große Siemer +8 more
2020Cytometry. Part B, Clinical cytometry18 citations Open access
Semantic Scholar
HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition
A. A. Jaguva Vasudevan, M. Hoffmann, M. L. Beck, G. Poschmann +6 more
2019International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase‐ and proteasome‐mediated Mcl‐1 degradation
Tamara Hornstein, S. Lehmann, Denise Philipp, S. Detmer +7 more
2016Journal of Leukocyte Biology16 citations Open access
Semantic Scholar
Establishment and Evaluation of Dual HDAC/BET Inhibitors as Therapeutic Options for Germ Cell Tumors and Other Urological Malignancies
A. Burmeister, A. Stephan, L. A. Alves Avelar, Melanie R. Müller +13 more
2022Molecular Cancer Therapeutics14 citations Open access
Semantic Scholar
Long lasting response to anti-PD-1 therapy of recurrent conjunctival squamous cell carcinoma - a case report and systematic review of the literature
M. Hoffmann, J. Schardt, C. Ionescu, Ute E. K. Wolf-Schnurrbusch +4 more
202114 citations Open access
Semantic Scholar
Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1
Lars Erichsen, H. Seifert, W. Schulz, M. Hoffmann +10 more
2020Scientific Reports14 citations Open access
Semantic Scholar
Many Different LINE-1 Retroelements Are Activated in Bladder Cancer
P. Whongsiri, W. Goering, Tobias Lautwein, C. Hader +4 more
2020International Journal of Molecular Sciences14 citations Open access
Semantic Scholar

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