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R. Piskol · SciRah

Researcher profile · Semantic Scholar

R. Piskol

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R. Piskol — researcher profile on SciRah

h-index: 24
Works: 64
Citations: 5,103

Most-cited papers

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
Brian J. Liddicoat, R. Piskol, A. Chalk, G. Ramaswami +5 more
2015Science869 citations Open access
Semantic Scholar
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
F. de Sousa e Melo, A. Kurtova, J. Harnoss, Noelyn M. Kljavin +9 more
2017Nature715 citations
Semantic Scholar
Dynamic landscape and regulation of RNA editing in mammals
M. Tan, Qin Li, Raghuvaran Shanmugam, R. Piskol +25 more
2017Nature583 citations Open access
Semantic Scholar
Accurate identification of human Alu and non-Alu RNA editing sites
G. Ramaswami, Wei Lin, R. Piskol, M. Tan +2 more
2012Nature Methods362 citations Open access
Semantic Scholar
Reliable identification of genomic variants from RNA-seq data.
R. Piskol, G. Ramaswami, J. B. Li
2013American Journal of Human Genetics357 citations Open access
Semantic Scholar
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Yi Zhou, M. Fei, Gu Zhang, Wei-Ching Liang +24 more
2020Immunity354 citations Open access
Semantic Scholar
Comment on “Widespread RNA and DNA Sequence Differences in the Human Transcriptome”
Wei Lin, R. Piskol, M. Tan, J. B. Li
2012Science214 citations
Semantic Scholar
Explorer Identifying RNA editing sites using RNA sequencing data alone
G. Ramaswami, Rui Zhang, R. Piskol, L. Keegan +3 more
2017188 citations
Semantic Scholar
Identifying RNA editing sites using RNA sequencing data alone
G. Ramaswami, Rui Zhang, R. Piskol, L. Keegan +3 more
2013Nature Methods166 citations Open access
Semantic Scholar
CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity
Ji Li, R. Piskol, R. Ybarra, Y. Chen +8 more
2019Science Translational Medicine147 citations Open access
Semantic Scholar
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
T. Fernando, R. Piskol, Russell Bainer, E. Sokol +9 more
2020Nature Communications134 citations Open access
Semantic Scholar
A cell identity switch allows residual BCC to survive Hedgehog pathway inhibition
B. Biehs, G. J. Dijkgraaf, R. Piskol, B. Alicke +4 more
2018Nature123 citations
Semantic Scholar
ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma
Ivana Yen, Frances Shanahan, Jeeyun Lee, Yong S. Hong +35 more
2021Nature112 citations Open access
Semantic Scholar
A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells
Aaron H. Nile, F. de Sousa e Melo, S. Mukund, R. Piskol +14 more
2018Nature Chemical Biology76 citations
Semantic Scholar
Lack of evidence for existence of noncanonical RNA editing
R. Piskol, Zhi-Yu Peng, Jun Wang, J. B. Li
2013Nature Biotechnology72 citations
Semantic Scholar
Stem cell plasticity enables hair regeneration following Lgr5+ cell loss
J. Hoeck, B. Biehs, A. Kurtova, Noelyn M. Kljavin +6 more
2017Nature Cell Biology71 citations
Semantic Scholar
Allelic Expression of Deleterious Protein-Coding Variants across Human Tissues
Kimberly R. Kukurba, Rui Zhang, Xin Li, Kevin S. Smith +8 more
2014PLoS Genetics66 citations Open access
Semantic Scholar
Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis
Brian J. Liddicoat, Jochen C. Hartner, R. Piskol, G. Ramaswami +11 more
2016Experimental Hematology62 citations Open access
Semantic Scholar
A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer
R. Piskol, L. Huw, Ismail Sergin, Christiaan Kljin +14 more
2019Clinical Cancer Research48 citations Open access
Semantic Scholar
Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells.
Putianqi Wang, Noelyn M. Kljavin, Thi Thu Thao Nguyen, E. Storm +6 more
2023Cell Stem Cell44 citations Open access
Semantic Scholar
Identifying transcriptional programs underlying cancer drug response with TraCe-seq
Matthew T. Chang, Frances Shanahan, Thi Thu Thao Nguyen, S. Staben +11 more
2021Nature Biotechnology41 citations
Semantic Scholar
CRAF dimerization with ARAF regulates KRAS-driven tumor growth.
Avinashnarayan Venkatanarayan, Jason Liang, Ivana Yen, Frances Shanahan +19 more
2022Cell Reports38 citations Open access
Semantic Scholar
Machine learning and chemico-genomics approach defines and predicts cross-talk of Hippo and MAPK pathways.
Trang Pham, Thijs J. Hagenbeek, Ho-June Lee, Jason Li +14 more
2020Cancer Discovery25 citations
Semantic Scholar
An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer
Sunil Bhakta, Lisa M. Crocker, Yvonne M. Chen, Meredith Hazen +19 more
2017Molecular Cancer Therapeutics25 citations Open access
Semantic Scholar
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity
Aurélie Hérault, Judy Mak, Josefa Dela Cruz-Chuh, Michael Dillon +25 more
2024Cancer Immunology and Immunotherapy24 citations
Semantic Scholar
Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/β-catenin signaling
S. Hansen, Ying-Nan Zhang, Sunhee Hwang, A. Nabhan +10 more
2022Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
MAP4K4 negatively regulates CD8 T cell–mediated antitumor and antiviral immunity
E. Esen, Ismail Sergin, Rajiv Jesudason, Patricia Himmels +10 more
2020Science immunology22 citations
Semantic Scholar
Analyzing the evolution of RNA secondary structures in vertebrate introns using Kimura's model of compensatory fitness interactions.
R. Piskol, W. Stephan
2008Molecular biology and evolution22 citations Open access
Semantic Scholar
The small RNA expression profile of the developing murine urinary and reproductive systems
Ana Laura Gutierrez Aguilar, R. Piskol, M. Beitzinger, Jiayun Zhu +5 more
2010FEBS Letters18 citations Open access
Semantic Scholar
Modulation of fibronectin extracellular matrix enhances anti-tumor efficacy of immune checkpoint blockade
Kabir A. Khan, Maresa Caunt Mitzner, W. Cruz-Muñoz, Grant Li +11 more
2025Cell Reports Medicine15 citations Open access
Semantic Scholar
Novel Anti-LY6G6D/CD3 T-Cell–Dependent Bispecific Antibody for the Treatment of Colorectal Cancer
Pei-Yin Wang, L. Sun, Robyn Clark, Maria Hristopoulos +21 more
2022Molecular Cancer Therapeutics11 citations Open access
Semantic Scholar
Selective constraints in conserved folded RNAs of drosophilid and hominid genomes.
R. Piskol, W. Stephan
2011Molecular biology and evolution11 citations
Semantic Scholar
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma
G. Hegde, C. C. de la Cruz, J. Giltnane, Lisa M. Crocker +10 more
2019eLife9 citations Open access
Semantic Scholar
T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction
Patricia Himmels, Thi Thu Thao Nguyen, Maresa Caunt Mitzner, Alfonso Arrazate +13 more
2023EMBO Reports8 citations Open access
Semantic Scholar
The Role of the Effective Population Size in Compensatory Evolution
R. Piskol, W. Stephan
2011Genome Biology and Evolution8 citations Open access
Semantic Scholar
Notch signaling in thyrocytes is essential for adult thyroid function and mammalian homeostasis
Lluc Mosteiro, Thi Thu Thao Nguyen, Simona Hankeová, Daniel Álvarez-Sierra +10 more
2023Nature Metabolism7 citations
Semantic Scholar
Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema
Nicholas J. Agard, Gu Zhang, J. Ridgeway, D. Dicara +29 more
2022Translational Vision Science & Technology7 citations Open access
Semantic Scholar
Constitutive protein degradation induces acute cell death via proteolysis products
Si-Han Chen, Sumit Prakash, E. Helgason, Caroline L. Gilchrist +11 more
2023bioRxiv6 citations Open access
Semantic Scholar
A model of compensatory molecular evolution involving multiple sites in RNA molecules.
J. Kusumi, M. Ichinose, M. Takefu, R. Piskol +2 more
2016Journal of Theoretical Biology6 citations
Semantic Scholar
A high-MAPK, low-WNT cell state drives metastatic dissemination in colorectal cancer
Melanie Heinlein, G. Li, Noelyn M. Kljavin, Amanda R. Moore +10 more
2026Nature Cancer5 citations
Semantic Scholar
Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis
A. Kurtova, Melanie Heinlein, S. Haas, Lars Velten +17 more
2022Blood Advances5 citations Open access
Semantic Scholar
XenMine: A genomic interaction tool for the Xenopus community.
C. Reid, K. Karra, Jessica K. Chang, R. Piskol +4 more
2017Developmental Biology5 citations Open access
Semantic Scholar
Colon Cancer Heterogeneity: Welcome to the RiboZone.
R. Piskol, F. de Sousa e Melo
2020Cell Stem Cell3 citations Open access
Semantic Scholar
Tumor-targeted bispecific antibodies effectively inhibit oncogenic pathways while minimizing toxicity
Yvonne T. Kschonsak, Wei-Ching Liang, J. Chan, D. Kan +23 more
2026Science Advances2 citations Open access
Semantic Scholar
A-To-I RNA Editing By ADAR1 Is Essential For Hematopoiesis
R. Piskol, A. Chalk, Miyoko Higuchi, P. Seeburg +3 more
20132 citations
Semantic Scholar
Abstract PR002: T cell engager therapy affects the spatial distribution and phenotype of T cells in the tumor microenvironment
Billy Tomaszewski, M. Curtis, Conrad Foo, Gu Zhang +11 more
2025Cancer immunology research1 citations
Semantic Scholar
Author response: NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma
G. Hegde, C. C. de la Cruz, J. Giltnane, Lisa M. Crocker +10 more
20191 citations Open access
Semantic Scholar
Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells
Aaron H. Nile, F. de Sousa e Melo, S. Mukund, R. Piskol +14 more
2018Nature Chemical Biology1 citations Open access
Semantic Scholar
RNA editing is the primary in vivo function of ADAR1 and is essential for hematopoiesis
Brian J. Liddicoat, R. Piskol, J. B. Li, A. Chalk +4 more
20141 citations Open access
Semantic Scholar
E3 Ubiquitin Ligase Mind Bomb 1 is a Novel Negative Regulator of Tumor-Suppressive BMP Signaling
Charisa L Cottonham, Gloria E. Hernandez, Tommy K. Cheung, Christopher M. Rose +4 more
2026Cancer Research Communications0 citations Open access
Semantic Scholar

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