Raghuvaran Shanmugam

Most-cited papers

1. Dynamic landscape and regulation of RNA editing in mammals

   M. Tan, Qin Li, Raghuvaran Shanmugam, R. Piskol +25 more

   2017Nature583 citations Open access

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2. Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences

   Raghuvaran Shanmugam, J. Fierer, Steffen Kaiser, M. Helm +2 more

   2015Cell Discovery82 citations Open access

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3. Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells

   Yuan-Ming Wang, K. I. Liu, Norfala-Aliah Binte Sutrisnoh, H. Srinivasan +17 more

   2018Genome Biology80 citations Open access

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4. A human expression system based on HEK293 for the stable production of recombinant erythropoietin

   C. L. Chin, Justin B. Goh, H. Srinivasan, K. I. Liu +9 more

   2019Scientific Reports50 citations Open access

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5. Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties.

   Winfried Elhardt, Raghuvaran Shanmugam, T. Jurkowski, A. Jeltsch

   2015Biochimie47 citations

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6. The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu

   Raghuvaran Shanmugam, Muktak A. Aklujkar, Matthias Schäfer, R. Reinhardt +9 more

   2014Nucleic Acids Research34 citations Open access

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7. SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates

   Raghuvaran Shanmugam, Fan Zhang, H. Srinivasan, J. L. Charles Richard +7 more

   2018Nucleic Acids Research28 citations Open access

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8. Mapping the tRNA binding site on the surface of human DNMT2 methyltransferase.

   T. Jurkowski, Raghuvaran Shanmugam, M. Helm, A. Jeltsch

   2012Biochemistry27 citations

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9. Genome-wide screens identify specific drivers of mutant hTERT promoters

   Raghuvaran Shanmugam, M. Ozturk, Joo-Leng Low, S. C. Akıncılar +5 more

   2022Proceedings of the National Academy of Sciences of the United States of America18 citations Open access

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10. Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers

    Raghuvaran Shanmugam, Prativa Majee, Wei Shi, M. Ozturk +25 more

    2024Cancer Discovery13 citations Open access

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11. Multiomics and multi-region spatial transcriptome analysis reveal cellular networks and pathways associated with HCC recurrence

    V. P. Seshachalam, I. N. Sari, Kane Toh, Prativa Majee +34 more

    2026JHEP Reports1 citations Open access

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12. Multi-region spatial transcriptome analysis reveals cellular networks and pathways associated with hepatocellular carcinoma recurrence

    Aziz Aiderus, P. Seshachalam, Khaireen Idzham, Matias J. Caldez +23 more

    2023bioRxiv0 citations Open access

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13. Biochemical characterisation of tRNA-Asp methyltransferase Dnmt2 and its physiological significance

    Raghuvaran Shanmugam

    20140 citations

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