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A. Protter · SciRah

Researcher profile · Semantic Scholar

A. Protter

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A. Protter — researcher profile on SciRah

h-index: 43
Works: 113
Citations: 6,988

Most-cited papers

Activation of p38 mitogen‐activated protein kinase in spinal microglia is a critical link in inflammation‐induced spinal pain processing
Camilla I. Svensson, M. Marsala, A. Westerlund, N. Calcutt +7 more
2003Journal of Neurochemistry400 citations Open access
Semantic Scholar
Altered patterns of gene expression in response to myocardial infarction.
L. Stanton, L. Garrard, D. Damm, B. Garrick +6 more
2000Circulation Research381 citations
Semantic Scholar
Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide
D. Cochrane, S. Bernales, Britta M. Jacobsen, D. Cittelly +16 more
2014Breast Cancer Research374 citations Open access
Semantic Scholar
B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-&bgr; in Primary Human Cardiac Fibroblasts: Fibrosis, Myofibroblast Conversion, Proliferation, and Inflammation
A. Kapoun, Fa-Quan Liang, G. O'young, D. Damm +6 more
2004Circulation Research300 citations Open access
Semantic Scholar
Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia
Zhi-He Li, Ying Zhang, Jing Y. Ma, A. Kapoun +10 more
2007HYPERTENSION264 citations
Semantic Scholar
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor.
P. Bonniaud, P. Margetts, M. Kolb, J. Schroeder +8 more
2005American Journal of Respiratory and Critical Care Medicine264 citations
Semantic Scholar
Detection of Endogenous B-Type Natriuretic Peptide at Very Low Concentrations in Patients With Heart Failure
E. Niederkofler, U. Kiernan, J. O'Rear, S. Menon +4 more
2008Circulation: Heart Failure176 citations Open access
Semantic Scholar
The precursor to B-type natriuretic peptide is an O-linked glycoprotein.
U. Schellenberger, J. O'Rear, Andrew W. Guzzetta, R. A. Jue +2 more
2006Archives of Biochemistry and Biophysics170 citations
Semantic Scholar
Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase In vivo
Rongrong Ge, Vaishali Rajeev, Partha S. Ray, E. Lattime +9 more
2006Clinical Cancer Research156 citations
Semantic Scholar
Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE2 release and thermal hyperalgesia
C. Svensson, X. Hua, A. Protter, H. Powell +1 more
2003NeuroReport143 citations
Semantic Scholar
Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.
A. Zaiman, M. Podowski, S. Medicherla, Kimberley Gordy +11 more
2008American Journal of Respiratory and Critical Care Medicine126 citations Open access
Semantic Scholar
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer’s mouse model
John W. Steele, M. L. Lachenmayer, S. Ju, Aryeh Stock +26 more
2012Molecular Psychiatry114 citations Open access
Semantic Scholar
Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration‐resistant prostate cancer
J. Guerrero, Iván E. Alfaro, Francisco Gómez, A. Protter +1 more
2013The Prostate111 citations Open access
Semantic Scholar
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.
Thomas-Toan Tran, M. Uhl, Jing Y. Ma, L. Janssen +18 more
2007Neuro-Oncology102 citations Open access
Semantic Scholar
Inhibition of p38 MAP kinase activity enhances axonal regeneration.
Robert R. Myers, Yasufumi Sekiguchi, S. Kikuchi, B. Scott +3 more
2003Experimental Neurology93 citations
Semantic Scholar
p38α-Selective Mitogen-Activated Protein Kinase Inhibitor SD-282 Reduces Inflammation in a Subchronic Model of Tobacco Smoke-Induced Airway Inflammation
S. Medicherla, M. Fitzgerald, Dianne Spicer, P. Woodman +6 more
2008Journal of Pharmacology and Experimental Therapeutics91 citations
Semantic Scholar
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain
John W. Steele, S. Ju, M. L. Lachenmayer, Jessica Liken +19 more
2012Molecular Psychiatry82 citations Open access
Semantic Scholar
Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression.
A. Kapoun, N. Gaspar, Ying Wang, Debby Damm +15 more
2006Molecular Pharmacology82 citations
Semantic Scholar
Cognition-Enhancing Properties of Dimebon in a Rat Novel Object Recognition Task Are Unlikely to Be Associated with Acetylcholinesterase Inhibition or N-Methyl-d-aspartate Receptor Antagonism
M. Giorgetti, J. Gibbons, S. Bernales, Iván E. Alfaro +6 more
2010Journal of Pharmacology and Experimental Therapeutics81 citations
Semantic Scholar
Combination Therapy with a Second-Generation Androgen Receptor Antagonist and a Metastasis Vaccine Improves Survival in a Spontaneous Prostate Cancer Model
Andressa Ardiani, B. Farsaci, C. Rogers, A. Protter +4 more
2013Clinical Cancer Research79 citations Open access
Semantic Scholar
Antinociceptive action of a p38&agr; MAPK inhibitor, SD‐282, in a diabetic neuropathy model
S. Sweitzer, S. Medicherla, R. Almirez, S. Dugar +4 more
200475 citations
Semantic Scholar
A p38α Selective Mitogen-Activated Protein Kinase Inhibitor Prevents Periodontal Bone Loss
K. Kirkwood, Fei Li, Jill E. Rogers, Jodie Otremba +8 more
2007Journal of Pharmacology and Experimental Therapeutics74 citations
Semantic Scholar
A Selective p38α Mitogen-Activated Protein Kinase Inhibitor Reverses Cartilage and Bone Destruction in Mice with Collagen-Induced Arthritis
S. Medicherla, Jing Y. Ma, R. Mangadu, Ye-Bin Jiang +11 more
2006Journal of Pharmacology and Experimental Therapeutics74 citations
Semantic Scholar
Inhibition of p38α MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-XL, Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo
T. Navas, A. Nguyen, T. Hideshima, M. Reddy +17 more
2006Leukemia70 citations Open access
Semantic Scholar
Selective inhibition of p38alpha MAPK improves cardiac function and reduces myocardial apoptosis in rat model of myocardial injury.
Zhi-He Li, Jing Y. Ma, I. Kerr, S. Chakravarty +3 more
2006American Journal of Physiology. Heart and Circulatory Physiology68 citations
Semantic Scholar
Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction.
L. Ellmers, N. Scott, S. Medicherla, A. Pilbrow +5 more
2008Endocrinology67 citations
Semantic Scholar
Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
A. Nguyen, E. Stebbins, M. Henson, G. O'young +15 more
2006Experimental Cell Research67 citations
Semantic Scholar
Effect of Transforming Growth Factor-β Receptor I Kinase Inhibitor 2,4-Disubstituted Pteridine (SD-208) in Chronic Allergic Airway Inflammation and Remodeling
S. Leung, A. Niimi, A. Noble, T. Oates +4 more
2006Journal of Pharmacology and Experimental Therapeutics66 citations
Semantic Scholar
Coronary vasodilator effects of BNP: mechanisms of action in coronary conductance and resistance arteries.
C. Zellner, A. Protter, E. Ko, Madhusudhan R. Pothireddy +5 more
1999American Journal of Physiology. Heart and Circulatory Physiology66 citations
Semantic Scholar
Restricted delivery of talazoparib across the blood-brain barrier limits the sensitizing effects of poly (ADP-ribose) polymerase inhibition on temozolomide therapy in glioblastoma
S. Kizilbash, Shiv K. Gupta, Kenneth J. Chang, R. Kawashima +12 more
2017Molecular Cancer Therapeutics65 citations Open access
Semantic Scholar
Differential expression of cardiac ANP and BNP in a rabbit model of progressive left ventricular dysfunction.
Andreas Luchner, F. Muders, O. Dietl, E. Friedrich +4 more
2001Cardiovascular Research62 citations
Semantic Scholar
Efficacy and specificity of bFGF increased collateral flow in experimental peripheral arterial insufficiency.
H.-T. Yang, Y. Feng, L. A. Allen, A. Protter +1 more
2000American Journal of Physiology. Heart and Circulatory Physiology61 citations
Semantic Scholar
Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness.
P. Nath, S. Leung, A. S. Williams, A. Noble +6 more
2006European Journal of Pharmacology56 citations
Semantic Scholar
Peripheral and central p38 MAPK mediates capsaicin‐induced hyperalgesia
S. Sweitzer, M. Peters, J.-Y. Ma, I. Kerr +6 more
2004Pain54 citations
Semantic Scholar
Antitumor Activity of TGF-β, Inhibitor is Dependent on the Microenvironment
S. Medicherla, Ling-Yun Li, Jing Y. Ma, A. Kapoun +8 more
200748 citations
Semantic Scholar
A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis.
S. Medicherla, Jing Y. Ma, R. Mangadu, Ye-Bin Jiang +11 more
2006Journal of Pharmacology and Experimental Therapeutics45 citations
Semantic Scholar
p38 Inhibition attenuates the pro-inflammatory response to C-reactive protein by human peripheral blood mononuclear cells.
M. Lim, Hui Wang, A. Kapoun, Maile O'connell +8 more
2004Journal of Molecular and Cellular Cardiology44 citations
Semantic Scholar
Inhibition of p38α Mitogen-Activated Protein Kinase Prevents the Development of Osteolytic Bone Disease, Reduces Tumor Burden, and Increases Survival in Murine Models of Multiple Myeloma
K. Vanderkerken, S. Medicherla, L. Coulton, H. de Raeve +7 more
200741 citations Open access
Semantic Scholar
p38 MAPK inhibition reduces diabetes-induced impairment of wound healing
S. Medicherla, S. Wadsworth, B. Cullen, D. Silcock +8 more
2009Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy40 citations Open access
Semantic Scholar
p38α Mitogen-Activated Protein Kinase Inhibition Improves Cardiac Function and Reduces Myocardial Damage in Isoproterenol-Induced Acute Myocardial Injury in Rats
Zhi-He Li, T. Tran, Jing Y. Ma, G. O'young +5 more
2004Journal of Cardiovascular Pharmacology40 citations Open access
Semantic Scholar
Novel p38α Mitogen‐Activated Protein Kinase Inhibitor Shows Analgesic Efficacy in Acute Postsurgical Dental Pain
Sandra E. Tong, S. Daniels, P. Black, Stephen Chang +2 more
2012Journal of clinical pharmacology38 citations
Semantic Scholar
Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo.
T. Navas, A. Nguyen, T. Hideshima, M. Reddy +17 more
2006Leukemia35 citations
Semantic Scholar
B-Type natriuretic peptide inhibited angiotensin II-stimulated cholesterol biosynthesis, cholesterol transfer, and steroidogenesis in primary human adrenocortical cells.
Fa-Quan Liang, A. Kapoun, Andrew D. Lam, Debby Damm +3 more
2007Endocrinology34 citations Open access
Semantic Scholar
Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment.
S. Medicherla, Ling-Yun Li, Jing Y. Ma, A. Kapoun +8 more
2007Anticancer Research34 citations
Semantic Scholar
Role of p38 mitogen activated protein kinase in a model of osteosarcoma-induced pain.
C. Svensson, S. Medicherla, S. Malkmus, Ye-Bin Jiang +10 more
2008Pharmacology, Biochemistry and Behavior28 citations
Semantic Scholar
p38alpha-selective MAP kinase inhibitor reduces tumor growth in mouse xenograft models of multiple myeloma.
S. Medicherla, M. Reddy, Jing Ying, T. Navas +6 more
2008Anticancer Research27 citations
Semantic Scholar
Clinical Implications of Defective B‐Type Natriuretic Peptide
S. Menon, R. Mills, U. Schellenberger, Syed Saqhir +1 more
2009Clinical Cardiology23 citations Open access
Semantic Scholar
B-type natriuretic peptide for the treatment of congestive heart failure.
G. Schreiner, A. Protter
2002Current opinion in pharmacology (Print)22 citations
Semantic Scholar
Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.
R. Rai, Monali Banerjee, Darren H. Wong, E. McCullagh +19 more
2016Bioorganic & Medicinal Chemistry Letters17 citations
Semantic Scholar
Topical alpha-selective p38 MAP kinase inhibition reduces acute skin inflammation in guinea pig
S. Medicherla, Jing Y. Ma, M. Reddy, I. Esikova +4 more
2010Journal of Inflammation Research17 citations Open access
Semantic Scholar

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S. Chakravarty×18
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L. Higgins×18
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A. Kapoun×17
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S. Dugar — researcher profile on SciRah

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Jing Y. Ma — researcher profile on SciRah

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