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Rajeevan Selvaratnam · SciRah

Researcher profile · Semantic Scholar

Rajeevan Selvaratnam

University of Toronto

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Rajeevan Selvaratnam — researcher profile on SciRah

ORCID iD 0000-0003-4457-616XHomepage

h-index: 18
Works: 37
Citations: 1,146

Most-cited papers

Mapping allostery through the covariance analysis of NMR chemical shifts
Rajeevan Selvaratnam, S. Chowdhury, B. VanSchouwen, G. Melacini
2011Proceedings of the National Academy of Sciences of the United States of America216 citations Open access
Semantic Scholar
Signaling through dynamic linkers as revealed by PKA
M. Akimoto, Rajeevan Selvaratnam, E. T. McNicholl, Geeta Verma +2 more
2013Proceedings of the National Academy of Sciences of the United States of America100 citations Open access
Semantic Scholar
The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.
Rajeevan Selvaratnam, B. VanSchouwen, F. Fogolari, M. Mazhab-Jafari +2 more
2012Biophysical Journal85 citations Open access
Semantic Scholar
A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP*
M. Akimoto, Zai-Yong Zhang, Stephen Boulton, Rajeevan Selvaratnam +5 more
2014Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains*
Rahul K. Das, S. Chowdhury, M. Mazhab-Jafari, Soumita SilDas +2 more
2009Journal of Biological Chemistry71 citations Open access
Semantic Scholar
The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR
Rajeevan Selvaratnam, M. Mazhab-Jafari, Rahul K. Das, G. Melacini
2012PLoS ONE68 citations Open access
Semantic Scholar
Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I
G. Huang, J. J. Kim, A. Reger, R. Lorenz +11 more
2013Structure63 citations Open access
Semantic Scholar
A Tool Set to Map Allosteric Networks through the NMR Chemical Shift Covariance Analysis
Stephen Boulton, M. Akimoto, Rajeevan Selvaratnam, Amir Bashiri +1 more
2014Scientific Reports59 citations Open access
Semantic Scholar
Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP*
Rahul K. Das, M. Mazhab-Jafari, S. Chowdhury, Soumita SilDas +2 more
2008Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)*♦
B. VanSchouwen, Rajeevan Selvaratnam, Rajanish Giri, R. Lorenz +3 more
2015Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Serum Free Light Chain Analysis
Rajeevan Selvaratnam, Jing Cao, A. Karger
201635 citations
Semantic Scholar
Noradrenergic modulation of hypoglossal motoneuron excitability: developmental and putative state-dependent mechanisms.
G. Funk, J. Zwicker, Rajeevan Selvaratnam, D. M. Robinson
2011Archives Italiennes de Biologie35 citations
Semantic Scholar
Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist.
Stephen Boulton, Rajeevan Selvaratnam, J. Blondeau, F. Lezoualc'h +1 more
2018Journal of the American Chemical Society33 citations
Semantic Scholar
Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)*
B. VanSchouwen, Rajeevan Selvaratnam, F. Fogolari, G. Melacini
2011Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators
Stephen Boulton, Rajeevan Selvaratnam, Rashik Ahmed, Katherine Van +2 more
2019Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
Implementation of the NMR CHEmical Shift Covariance Analysis (CHESCA): A Chemical Biologist's Approach to Allostery.
Stephen Boulton, Rajeevan Selvaratnam, Rashik Ahmed, G. Melacini
2018Methods in molecular biology21 citations
Semantic Scholar
A Novel Non-canonical Forkhead-associated (FHA) Domain-binding Interface Mediates the Interaction between Rad53 and Dbf4 Proteins*
L. Matthews, Rajeevan Selvaratnam, Darryl R. Jones, M. Akimoto +4 more
2013Journal of Biological Chemistry20 citations Open access
Semantic Scholar
cAMP-dependent allostery and dynamics in Epac: an NMR view.
Rajeevan Selvaratnam, M. Akimoto, B. VanSchouwen, G. Melacini
2012Biochemical Society Transactions20 citations
Semantic Scholar
Allosteric linkers in cAMP signalling
M. Akimoto, Kody Moleschi, Stephen Boulton, B. VanSchouwen +3 more
2014Biochemical Society Transactions16 citations Open access
Semantic Scholar
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR.
Stephen Boulton, M. Akimoto, B. VanSchouwen, Kody Moleschi +3 more
2014Biochemical Society Transactions16 citations
Semantic Scholar
Ultrasonic and densimetric characterization of the association of cyclic AMP with the cAMP-binding domain of the exchange protein EPAC1.
Ikbae Son, Rajeevan Selvaratnam, D. Dubins, G. Melacini +1 more
2013Journal of Physical Chemistry B14 citations
Semantic Scholar
Defining Appropriate Utilization of AST Testing.
Z. Mohammed-Ali, D. Brinc, V. Kulasingam, Rajeevan Selvaratnam
2020Clinical Biochemistry13 citations
Semantic Scholar
Analytical performance evaluation of thyroid-stimulating hormone receptor antibody (TRAb) immunoassays.
V. Higgins, K. Patel, V. Kulasingam, D. Beriault +2 more
2020Clinical Biochemistry10 citations
Semantic Scholar
Pediatric reference intervals for endocrine markers in healthy children and adolescents on the Liaison XL (DiaSorin) immunoassay system.
J. J. Miller, M. Bohn, V. Higgins, M. Nichols +5 more
2023Clinical Biochemistry7 citations
Semantic Scholar
The Importance of Verifying Reference Intervals for Calculated Results.
Rajeevan Selvaratnam, A. Karger
2017The Journal of Applied Laboratory Medicine5 citations Open access
Semantic Scholar
Identification of Core Allosteric Sites through Temperature- and Nucleus-Invariant Chemical Shift Covariance.
Hebatallah B. Mohamed, Ubaidullah Baryar, Amir Bashiri, Rajeevan Selvaratnam +2 more
2022Biophysical Journal4 citations Open access
Semantic Scholar
Optimizing Measurement and Interpretation of the G6PD/Hb Ratio.
V. Higgins, P. Cheng, Rajeevan Selvaratnam, D. Brinc
2021The Journal of Applied Laboratory Medicine2 citations Open access
Semantic Scholar
Structures of human PKG reveal cGMP-selectived activation mechanisms
G. Huang, J. J. Kim, A. Reger, R. Lorenz +11 more
2013BMC Pharmacology and Toxicology2 citations Open access
Semantic Scholar
PROBING ALLOSTERY IN THE EXCHANGE PROTEIN DIRECTLY ACTIVATED BY cAMP (EPAC) USING NMR SPECTROSCOPY
Rajeevan Selvaratnam
20131 citations
Semantic Scholar
Response to 'ROC can be used to determine the optimal threshold of ALT for reflex to AST testing'.
Z. Mohammed-Ali, Rajeevan Selvaratnam
2020Clinical Biochemistry0 citations
Semantic Scholar
71 A Comparison of Urinary Cell Cycle Markers of Acute Kidney Injury ([IGFBP7]*[TIMP2]) and the Product of Classic Urinary Markers [Albumin]*[Creatinine]
Rajeevan Selvaratnam, Beth Stodardt, A. Milligan
20180 citations Open access
Semantic Scholar
Mechanism of Cyclic AMP Partial Agonism in Protein Kinase G (PKG)
B. VanSchouwen, Rajeevan Selvaratnam, Rajanish Giri, R. Lorenz +3 more
20160 citations Open access
Semantic Scholar
A Tool Set to Map Dynamic Allosteric Networks through the NMR Chemical Shift Covariance Analysis (CHESCA)
Stephen Boulton, M. Akimoto, Rajeevan Selvaratnam, Amir Bashiri +1 more
20150 citations Open access
Semantic Scholar
Finding Order in Disorder: Probing Transient Functional States in the Amyloidogenic Alzheimer's Aβ Peptide Using the NMR Chemical Shift Covariance Analysis (CHESCA)
Moustafa Algamal, Julijana Milojevic, Naeimeh Jafari, Shenmin Zhang +2 more
20140 citations Open access
Semantic Scholar
Nucleotide-Gated ( HCN ) Channel Opening Hyperpolarization-Activated Cyclic A Mechanism for the Auto-Inhibition of Signal Transduction :
O. Lange, Giuseppe Melacini VanSchouwen, Melanie Gloyd, E. Accili +3 more
20140 citations
Semantic Scholar
Apo Structure of human HCN4 CNBD solved by NMR
M. Akimoto, Z. Zhang, Stephen Boulton, Rajeevan Selvaratnam +5 more
20140 citations
Semantic Scholar
Structures of human PKG reveal cGMP-selectived activation mechanisms
G. Huang, J. J. Kim, A. Reger, R. Lorenz +11 more
2013BMC Pharmacology and Toxicology0 citations Open access
Semantic Scholar

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