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Rahul K. Das · SciRah

Researcher profile · Semantic Scholar

Rahul K. Das

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Rahul K. Das — researcher profile on SciRah

h-index: 33
Works: 79
Citations: 5,878

Most-cited papers

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
Rahul K. Das, R. Pappu
2013Proceedings of the National Academy of Sciences of the United States of America969 citations Open access
Semantic Scholar
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
N. Jura, Nicholas F. Endres, K. Engel, S. Deindl +5 more
2009Cell628 citations Open access
Semantic Scholar
Architecture and membrane interactions of the EGF receptor
A. Arkhipov, Y. Shan, Rahul K. Das, Nicholas F. Endres +4 more
2013Cell521 citations Open access
Semantic Scholar
Conformational Coupling Across the Plasma Membrane in Activation of the EGF receptor
Nicholas F. Endres, Rahul K. Das, Adam W. Smith, A. Arkhipov +8 more
2013Cell520 citations Open access
Semantic Scholar
CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins
A. Holehouse, Rahul K. Das, J. N. Ahad, Mary O. G. Richardson +1 more
2017Biophysical Journal469 citations Open access
Semantic Scholar
Relating sequence encoded information to form and function of intrinsically disordered proteins
Rahul K. Das, Kiersten M. Ruff, R. Pappu
2015Current Opinion in Structural Biology399 citations Open access
Semantic Scholar
A high-throughput mutational scan of an intrinsically disordered acidic transcriptional activation domain
M. Staller, A. Holehouse, Devjanee Swain-Lenz, Rahul K. Das +2 more
2018Cell Systems163 citations Open access
Semantic Scholar
cAMP activation of PKA defines an ancient signaling mechanism
Rahul K. Das, V. Esposito, M. Abu-Abed, G. Anand +2 more
2007Proceedings of the National Academy of Sciences of the United States of America131 citations Open access
Semantic Scholar
Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor
Kathryn P. Sherry, Rahul K. Das, R. Pappu, D. Barrick
2017Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting.
R. Pathania, S. Zlitni, C. Barker, Rahul K. Das +6 more
2009Nature Chemical Biology118 citations Open access
Semantic Scholar
Cryptic sequence features within the disordered protein p27Kip1 regulate cell cycle signaling
Rahul K. Das, Yong-Qi Huang, Aaron H. Phillips, R. Kriwacki +1 more
2016Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
Understanding the molecular basis for the inhibition of the Alzheimer's Abeta-peptide oligomerization by human serum albumin using saturation transfer difference and off-resonance relaxation NMR spectroscopy.
Julijana Milojevic, V. Esposito, Rahul K. Das, G. Melacini
2007Journal of the American Chemical Society113 citations
Semantic Scholar
Regulation of the catalytic activity of the EGF receptor
Nicholas F. Endres, K. Engel, Rahul K. Das, E. Kovács +1 more
2011Current Opinion in Structural Biology100 citations Open access
Semantic Scholar
Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor
E. Kovács, Rahul K. Das, Qi Wang, Timothy S. Collier +9 more
2015Molecular and Cellular Biology88 citations Open access
Semantic Scholar
The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.
Rajeevan Selvaratnam, B. VanSchouwen, F. Fogolari, M. Mazhab-Jafari +2 more
2012Biophysical Journal85 citations Open access
Semantic Scholar
Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins
R. Beveridge, Lukasz G. Migas, Rahul K. Das, R. Pappu +2 more
2018Journal of the American Chemical Society84 citations Open access
Semantic Scholar
A quantitative measure for protein conformational heterogeneity.
Nicholas Lyle, Rahul K. Das, R. Pappu
2013Journal of Chemical Physics83 citations Open access
Semantic Scholar
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1
J. Iwig, Y. Vercoulen, Rahul K. Das, Tiago F. Barros +6 more
2013eLife78 citations Open access
Semantic Scholar
Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains*
Rahul K. Das, S. Chowdhury, M. Mazhab-Jafari, Soumita SilDas +2 more
2009Journal of Biological Chemistry71 citations Open access
Semantic Scholar
The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR
Rajeevan Selvaratnam, M. Mazhab-Jafari, Rahul K. Das, G. Melacini
2012PLoS ONE68 citations Open access
Semantic Scholar
Coupling between motor proteins determines dynamic behaviors of motor protein assemblies.
J. Driver, A. R. Rogers, D. K. Jamison, Rahul K. Das +2 more
2010Physical Chemistry, Chemical Physics - PCCP67 citations
Semantic Scholar
N-terminal segments modulate the α-helical propensities of the intrinsically disordered basic regions of bZIP proteins.
Rahul K. Das, Scott L. Crick, R. Pappu
2012Journal of Molecular Biology60 citations
Semantic Scholar
Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP*
Rahul K. Das, M. Mazhab-Jafari, S. Chowdhury, Soumita SilDas +2 more
2008Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations*
E. T. McNicholl, Rahul K. Das, Soumita SilDas, Susan S. Taylor +1 more
2010Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Fuzzy regions in an intrinsically disordered protein impair protein–protein interactions
Antoine Gruet, Marion Dosnon, D. Blocquel, J. Brunel +7 more
2016The FEBS Journal43 citations Open access
Semantic Scholar
CIDER: Classification of Intrinsically Disordered Ensemble Regions
A. Holehouse, J. N. Ahad, Rahul K. Das, R. Pappu
201542 citations Open access
Semantic Scholar
Drosophila Tribbles Antagonizes Insulin Signaling-Mediated Growth and Metabolism via Interactions with Akt Kinase
Rahul K. Das, Zachary L. Sebo, Laramie Pence, L. Dobens
2014PLoS ONE40 citations Open access
Semantic Scholar
Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA.
C. Barker, Sarah E. Allison, S. Zlitni, Nicki Nguyen +4 more
2013Bioorganic & Medicinal Chemistry Letters39 citations Open access
Semantic Scholar
A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain*
Rahul K. Das, G. Melacini
2007Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states.
M. Mazhab-Jafari, Rahul K. Das, Steven A Fotheringham, Soumita SilDas +2 more
2007Journal of the American Chemical Society39 citations
Semantic Scholar
Definition of an electrostatic relay switch critical for the cAMP‐dependent activation of protein kinase A as revealed by the D170A mutant of RIα
M. Abu-Abed, Rahul K. Das, Li-Jun Wang, G. Melacini
2007Proteins: Structure, Function, and Bioinformatics36 citations
Semantic Scholar
Conservation of gene and tissue networks regulating insulin signalling in flies and vertebrates.
Rahul K. Das, L. Dobens
2015Biochemical Society Transactions33 citations
Semantic Scholar
The kinase domain of Drosophila Tribbles is required for turnover of fly C/EBP during cell migration.
Venessa Masoner, Rahul K. Das, Laramie Pence, Gaurav Anand +4 more
2013Developmental Biology33 citations Open access
Semantic Scholar
Mapping allostery through equilibrium perturbation NMR spectroscopy.
Rahul K. Das, M. Abu-Abed, G. Melacini
2006Journal of the American Chemical Society32 citations
Semantic Scholar
Antidiabetic role of a novel protein from garlic via NO in expression of Glut-4/insulin in liver of alloxan induced diabetic mice.
Suman Bhattacharya, U. Maji, G. Khan, Rahul K. Das +3 more
2019Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie29 citations Open access
Semantic Scholar
A novel protein tyrosine phosphatase like phytase from Lactobacillus fermentum NKN51: Cloning, characterization and application in mineral release for food technology applications.
Rekha Sharma, Piyush Kumar, V. Kaushal, Rahul K. Das +1 more
2018Bioresource Technology29 citations
Semantic Scholar
Facilitated search of proteins on DNA: correlations are important.
Rahul K. Das, A. Kolomeisky
2010Physical Chemistry, Chemical Physics - PCCP28 citations
Semantic Scholar
Unmasking Functional Motifs Within Disordered Regions of Proteins
Rahul K. Das, Albert H. Mao, R. Pappu
2012Science Signaling25 citations
Semantic Scholar
Elucidating the regulation of glucose tolerance in a β-glucosidase from Halothermothrix orenii by active site pocket engineering and computational analysis.
S. Sinha, Shibashis Das, Sukanya Konar, P. Ghorai +2 more
2020International Journal of Biological Macromolecules24 citations Open access
Semantic Scholar
Molecular basis of VEGFR1 autoinhibition at the plasma membrane
M. Chakraborty, Diptatanu Das, Purav Mondal, Pragya Kaul +3 more
2023bioRxiv22 citations Open access
Semantic Scholar
Disruption of the Microtubule Network and Inhibition of VEGFR2 Phosphorylation by Cytotoxic N,O-Coordinated Pt(II) and Ru(II) Complexes of Trimethoxy Aniline-Based Schiff Bases.
S. Acharya, M. Maji, M. Chakraborty, Indira Bhattacharya +3 more
2021Inorganic Chemistry19 citations
Semantic Scholar
Advances in isolation, characterization, modification, and application of Chenopodium starch: A comprehensive review.
Ankan Kheto, Rahul K. Das, Saptashish Deb, Yograj Bist +3 more
2022International Journal of Biological Macromolecules18 citations
Semantic Scholar
An allosteric hot spot in the tandem-SH2 domain of ZAP-70 regulates T-cell signaling
K. Gangopadhyay, Bharat Manna, Swarnendu Roy, S. Kumari +4 more
2019bioRxiv15 citations Open access
Semantic Scholar
How is functional specificity achieved through disordered regions of proteins?
Rahul K. Das, A. Mittal, R. Pappu
2013Bioessays15 citations
Semantic Scholar
A Drosophila model of insulin resistance associated with the human TRIB3 Q/R polymorphism
Zachary Fischer, Rahul K. Das, Anna Shipman, Jin-Yuan Fan +3 more
2017Disease Models & Mechanisms13 citations Open access
Semantic Scholar
Mapping polypeptide self-recognition through (1)H off-resonance relaxation.
V. Esposito, Rahul K. Das, G. Melacini
2005Journal of the American Chemical Society13 citations
Semantic Scholar
Dynamic properties of molecular motors in the divided-pathway model.
Rahul K. Das, A. Kolomeisky
2009Physical Chemistry, Chemical Physics - PCCP12 citations
Semantic Scholar
Spatial fluctuations affect the dynamics of motor proteins.
Rahul K. Das, A. Kolomeisky
2008Journal of Physical Chemistry B11 citations
Semantic Scholar
NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit
V. Esposito, T. Sjoberg, Rahul K. Das, Simon H. J. Brown +2 more
2006Journal of Biomolecular NMR9 citations
Semantic Scholar
Interaction between motor domains can explain the complex dynamics of heterodimeric kinesins.
Rahul K. Das, A. Kolomeisky
2007Physical review. E, Statistical, nonlinear, and soft matter physics8 citations Open access
Semantic Scholar

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