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Stephen Boulton · SciRah

Researcher profile · Semantic Scholar

Stephen Boulton

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Stephen Boulton — researcher profile on SciRah

h-index: 19
Works: 43
Citations: 985

Most-cited papers

Biochemical and Pharmacological Characterizations of ESI-09 Based EPAC Inhibitors: Defining the ESI-09 “Therapeutic Window”
Ying-Min Zhu, Haijun Chen, Stephen Boulton, F. Mei +4 more
2015Scientific Reports101 citations Open access
Semantic Scholar
Extracellular Vesicles and Viruses: Two Intertwined Entities
Coline Moulin, M. Crupi, C. Ilkow, J. Bell +1 more
2023International Journal of Molecular Sciences77 citations Open access
Semantic Scholar
Advances in NMR Methods To Map Allosteric Sites: From Models to Translation.
Stephen Boulton, G. Melacini
2016Chemical Reviews76 citations
Semantic Scholar
A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP*
M. Akimoto, Zai-Yong Zhang, Stephen Boulton, Rajeevan Selvaratnam +5 more
2014Journal of Biological Chemistry74 citations Open access
Semantic Scholar
A Tool Set to Map Allosteric Networks through the NMR Chemical Shift Covariance Analysis
Stephen Boulton, M. Akimoto, Rajeevan Selvaratnam, Amir Bashiri +1 more
2014Scientific Reports59 citations Open access
Semantic Scholar
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies
T. Azad, Reza Rezaei, R. Singaravelu, A. Pelin +22 more
2023Nature Communications47 citations Open access
Semantic Scholar
Atomic resolution map of the soluble amyloid beta assembly toxic surfaces
Rashik Ahmed, M. Akcan, A. Khondker, M. Rheinstädter +8 more
2019Chemical Science39 citations Open access
Semantic Scholar
Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist.
Stephen Boulton, Rajeevan Selvaratnam, J. Blondeau, F. Lezoualc'h +1 more
2018Journal of the American Chemical Society33 citations
Semantic Scholar
Characterization of Critical Determinants of ACE2–SARS CoV-2 RBD Interaction
Emily E. F. Brown, Reza Rezaei, T. Jamieson, Jaahnavi Dave +19 more
2021International Journal of Molecular Sciences28 citations Open access
Semantic Scholar
SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition
T. Azad, R. Singaravelu, E. E. Fekete, Zaid Taha +6 more
2021Biosensors & bioelectronics28 citations Open access
Semantic Scholar
Engineering vaccinia virus as an immunotherapeutic battleship to overcome tumor heterogeneity
A. Pelin, Stephen Boulton, Levi A. Tamming, J. Bell +1 more
2020Expert Opinion on Biological Therapy28 citations
Semantic Scholar
Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer
M. Crupi, Zaid Taha, T. J. Janssen, J. Petryk +25 more
2022Frontiers in Immunology27 citations Open access
Semantic Scholar
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators
Stephen Boulton, Rajeevan Selvaratnam, Rashik Ahmed, Katherine Van +2 more
2019Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection
Stephen Boulton, Joanna Poutou, N. Martin, T. Azad +27 more
2021Molecular Therapy26 citations Open access
Semantic Scholar
Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization
T. Azad, R. Singaravelu, M. Crupi, T. Jamieson +16 more
2020Membranes26 citations Open access
Semantic Scholar
Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis
T. Azad, Reza Rezaei, Abera Surendran, R. Singaravelu +4 more
2020Cancers25 citations Open access
Semantic Scholar
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry
T. Azad, R. Singaravelu, Zaid Taha, T. Jamieson +20 more
2021Molecular Therapy22 citations Open access
Semantic Scholar
Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective
Alveena Ahmed, Stephen Boulton, Hong-Zhao Shao, M. Akimoto +3 more
2019Cells22 citations Open access
Semantic Scholar
Implementation of the NMR CHEmical Shift Covariance Analysis (CHESCA): A Chemical Biologist's Approach to Allostery.
Stephen Boulton, Rajeevan Selvaratnam, Rashik Ahmed, G. Melacini
2018Methods in molecular biology21 citations
Semantic Scholar
‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7
A. W. Almawi, L. Matthews, Larasati, P. Myrox +7 more
2016Scientific Reports19 citations Open access
Semantic Scholar
Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia
Stephen Boulton, M. Akimoto, Sam Akbarizadeh, G. Melacini
2017Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Allosteric linkers in cAMP signalling
M. Akimoto, Kody Moleschi, Stephen Boulton, B. VanSchouwen +3 more
2014Biochemical Society Transactions16 citations Open access
Semantic Scholar
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR.
Stephen Boulton, M. Akimoto, B. VanSchouwen, Kody Moleschi +3 more
2014Biochemical Society Transactions16 citations
Semantic Scholar
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX
J. Whelan, R. Singaravelu, Fuan Wang, A. Pelin +23 more
2023Frontiers in Immunology14 citations Open access
Semantic Scholar
Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations
Naeimeh Jafari, J. D. Del Rio, M. Akimoto, J. Byun +10 more
2021Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist.
Hong-Zhao Shao, H. Mohamed, Stephen Boulton, Jin-Feng Huang +9 more
2020Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division
A. W. Almawi, Laurence Langlois-Lemay, Stephen Boulton, J. Rodríguez González +3 more
2020Scientific Reports12 citations Open access
Semantic Scholar
CHESPA/CHESCA-SPARKY: automated NMR data analysis plugins for SPARKY to map protein allostery
Hong-Zhao Shao, Stephen Boulton, C. Olivieri, Hebatallah B. Mohamed +6 more
2020Bioinform.12 citations Open access
Semantic Scholar
A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection
Stephen Boulton, Joanna Poutou, Rida Gill, Nouf Alluqmani +17 more
2023Molecular Therapy: Methods & Clinical Development9 citations Open access
Semantic Scholar
Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding.
Stephen Boulton, Katherine Van, B. VanSchouwen, Jerry Augustine +2 more
2020Biophysical Journal9 citations Open access
Semantic Scholar
Direct binding and internalization of diverse extracellular nucleic acid species through the collagenous domain of class A scavenger receptors
Kaushal Baid, Srinivas Nellimarla, Angela Huynh, Stephen Boulton +4 more
2018Immunology and Cell Biology9 citations
Semantic Scholar
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development
Stephen Boulton, M. Crupi, Siddharth Singh, Madalina E. Carter-Timofte +18 more
2023Journal of Biological Chemistry8 citations Open access
Semantic Scholar
A Highly Dynamic Loop of the Pseudomonas aeruginosa PA14 Type IV Pilin Is Essential for Pilus Assembly.
Y. Nguyen, Stephen Boulton, E. Tyler McNicholl, M. Akimoto +4 more
2018ACS Infectious Diseases6 citations
Semantic Scholar
Lipid binding protein response to a bile acid library: a combined NMR and statistical approach
S. Tomaselli, K. Pagano, Stephen Boulton, Serena Zanzoni +3 more
2015The FEBS Journal6 citations
Semantic Scholar
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen
Zaid Taha, R. Arulanandam, Glib Maznyi, Elena Godbout +29 more
2022Molecular Therapy5 citations Open access
Semantic Scholar
Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G.
B. VanSchouwen, Stephen Boulton, G. Melacini
2021Journal of Molecular Biology5 citations
Semantic Scholar
Nanoluciferase complementation-based biosensor reveals the importance of N- linked glycosylation of SARS-CoV-2 Spike for viral entry
T. Azad, R. Singaravelu, Zaid Taha, Stephen Boulton +15 more
20205 citations Open access
Semantic Scholar
Resonance assignments of asymmetric tetrameric platelet factor 4 (PF4)
Qiu-Lin Ma, Jin-Feng Huang, Stephen Boulton, Ellen Mak +10 more
2025Biomolecular NMR Assignments2 citations
Semantic Scholar
Non-Classical Protein Kinase a Activation by Aggregation of the PKA R-Subunits as a Mechanism of Inherited Carney Complex Mutations
Naeimeh Jafari, J. D. Del Rio, M. Akimoto, Olivia Byun +9 more
20210 citations Open access
Semantic Scholar
Characterization of Critical Determinants of ACE2-RBD Interaction
Emily E. F. Brown, Reza Rezaei, T. Jamieson, Jaahnavi Dave +19 more
2021bioRxiv0 citations Open access
Semantic Scholar
A tribute to Alexander Davidson Bain: An NMR pioneer and mentor at McMaster University
Christopher Kumar Anand, B. Berno, Stephen Boulton, M. Brook +5 more
20160 citations Open access
Semantic Scholar
A Tool Set to Map Dynamic Allosteric Networks through the NMR Chemical Shift Covariance Analysis (CHESCA)
Stephen Boulton, M. Akimoto, Rajeevan Selvaratnam, Amir Bashiri +1 more
20150 citations Open access
Semantic Scholar
Apo Structure of human HCN4 CNBD solved by NMR
M. Akimoto, Z. Zhang, Stephen Boulton, Rajeevan Selvaratnam +5 more
20140 citations
Semantic Scholar

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