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L. Scampavia · SciRah

Researcher profile · Semantic Scholar

L. Scampavia

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L. Scampavia — researcher profile on SciRah

h-index: 28
Works: 117
Citations: 2,670

Most-cited papers

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation
L. Plate, Christina B. Cooley, John J. Chen, Ryan J. Paxman +14 more
2016eLife216 citations Open access
Semantic Scholar
LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis.
A. Reed, Taka-Aki Ichu, Natalia Milosevich, B. Melillo +5 more
2022ACS Chemical Biology157 citations
Semantic Scholar
Pharmacologic IRE1/XBP1s Activation Confers Targeted ER Proteostasis Reprogramming
Julia M. Grandjean, Aparajita Madhavan, Lauren Cech, Bryan O. Seguinot +9 more
2020Nature Chemical Biology150 citations Open access
Semantic Scholar
Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate
Franck Madoux, D. Dreymuller, Jean-Phillipe Pettiloud, Radleigh G. Santos +8 more
2016Scientific Reports148 citations Open access
Semantic Scholar
Advanced Development of Primary Pancreatic Organoid Tumor Models for High Throughput Phenotypic Drug Screening
Shurong Hou, Hervé Triac, BanuPriya Sridharan, L. Scampavia +6 more
2018SLAS discovery : advancing life sciences R & D146 citations Open access
Semantic Scholar
Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication
Suzie Thenin-Houssier, Ian Mitchelle S. de Vera, Laura Pedró-Rosa, A. Brady +15 more
2016Antimicrobial Agents and Chemotherapy88 citations Open access
Semantic Scholar
SYNGAP1 Controls the Maturation of Dendrites, Synaptic Function, and Network Activity in Developing Human Neurons
N. Llamosas, Vineet Arora, Ridhima Vij, Murat Kilinc +11 more
2020Journal of Neuroscience64 citations Open access
Semantic Scholar
A 1536-Well 3D Viability Assay to Assess the Cytotoxic Effect of Drugs on Spheroids
Franck Madoux, Allison J. Tanner, Michelle Vessels, Lynsey Willetts +3 more
2017SLAS discovery : advancing life sciences R & D60 citations Open access
Semantic Scholar
Micro sequential injection: automated insulin derivatization and separation using a lab-on-valve capillary electrophoresis system.
Chao-Hsiang Wu, L. Scampavia, J. Ruzicka
2003In Analysis48 citations
Semantic Scholar
Automating a Magnetic 3D Spheroid Model Technology for High-Throughput Screening
Pierre Baillargeon, Justin Shumate, Shurong Hou, V. Fernandez-Vega +5 more
2019SLAS technology47 citations Open access
Semantic Scholar
A selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival
J. Chang, A. Zuhl, A. Speers, S. Niessen +15 more
2015ACS Chemical Biology46 citations Open access
Semantic Scholar
High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2
Emery Smith, Meredith E. Davis-Gardner, Rubén D. Garcia-Ordoñez, Tu-Trinh H. Nguyen +8 more
2020SLAS discovery : advancing life sciences R & D42 citations Open access
Semantic Scholar
Comparison of Miniaturized Time-Resolved Fluorescence Resonance Energy Transfer and Enzyme-Coupled Luciferase High-Throughput Screening Assays to Discover Inhibitors of Rho-Kinase II (ROCK-II)
T. Schröter, D. Minond, Amiee M. Weiser, C. Dao +12 more
2008Journal of biomolecular screening41 citations Open access
Semantic Scholar
Automated affinity capture-release of biotin-containing conjugates using a lab-on-valve apparatus coupled to UV/visible and electrospray ionization mass spectrometry.
Yuko Ogata, L. Scampavia, J. Ruzicka, C. R. Scott +2 more
2002Analytical Chemistry40 citations
Semantic Scholar
First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis
Prakash B. Palde, Ashima Bhaskar, Laura E. Pedró Rosa, Franck Madoux +6 more
2015ACS Chemical Biology38 citations Open access
Semantic Scholar
Identification of Potent Inhibitors of the Trypanosoma brucei Methionyl-tRNA Synthetase via High Throughput Orthogonal Screening
Laura Pedró-Rosa, Frederick S. Buckner, Ranae M. Ranade, C. Eberhart +12 more
2014Journal of biomolecular screening38 citations Open access
Semantic Scholar
Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells
S. Moghadasi, M. Esler, Yuka Otsuka, Jordan T. Becker +13 more
2022mBio37 citations Open access
Semantic Scholar
Bead injection ELISA for the determination of antibodies implicated in type 1 diabetes mellitus.
Andrea D Carroll, L. Scampavia, D. Luo, Å. Lernmark +1 more
2003In Analysis33 citations
Semantic Scholar
Identification of potent small molecule inhibitors of SARS-CoV-2 entry
S. Mediouni, H. Mou, Y. Otsuka, J. Jablonski +20 more
2021bioRxiv31 citations Open access
Semantic Scholar
A Cytotoxic Three-Dimensional-Spheroid, High-Throughput Assay using Patient Derived Glioma Stem Cells
V. Quereda, Shurong Hou, Franck Madoux, L. Scampavia +2 more
2018SLAS discovery : advancing life sciences R & D30 citations Open access
Semantic Scholar
Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
Lei-Ming Wang, Chiang-Min Cheng, J. Qin, Mafei Xu +13 more
2020Science Advances29 citations Open access
Semantic Scholar
Dynamic changes during the treatment of pancreatic cancer
R. Wolff, A. Wang-Gillam, H. Alvarez, H. Tiriac +26 more
2018OncoTarget29 citations Open access
Semantic Scholar
Lead Identification using 3D Models of Pancreatic Cancer
V. Fernandez-Vega, Shurong Hou, D. Plenker, H. Tiriac +7 more
2022SLAS discovery : advancing life sciences R & D28 citations Open access
Semantic Scholar
Label dilution method: a novel tool for bioligand interaction studies using bead injection in the lab-on-valve format.
Andrea D Carroll, L. Scampavia, J. Ruzicka
2002In Analysis28 citations
Semantic Scholar
The Scripps Molecular Screening Center and Translation Research Institute
Pierre Baillargeon, V. Fernandez-Vega, BanuPriya Sridharan, Steven J. Brown +5 more
2019SLAS discovery : advancing life sciences R & D27 citations Open access
Semantic Scholar
A Novel 3-dimensional High Throughput Screening Approach Identifies Inducers of a Mutant KRAS Selective Lethal Phenotype
Smitha Kota, Shurong Hou, W. Guerrant, Franck Madoux +7 more
2018Oncogene27 citations Open access
Semantic Scholar
Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4)
Emery Smith, P. Chase, C. Niswender, T. J. Utley +11 more
2015Journal of biomolecular screening25 citations Open access
Semantic Scholar
Assay strategies for identification of therapeutic leads that target protein trafficking
P. Conn, Timothy P. Spicer, L. Scampavia, J. Janovick
2015TIPS - Trends in Pharmacological Sciences25 citations Open access
Semantic Scholar
A Time-Resolved Fluorescence–Resonance Energy Transfer Assay for Identifying Inhibitors of Hepatitis C Virus Core Dimerization
Smitha Kota, L. Scampavia, T. Spicer, Aaron B. Beeler +5 more
2010Assay and drug development technologies25 citations Open access
Semantic Scholar
Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel
E. Chulkov, Emery Smith, Claudia M. Rohr, Nawal A Yahya +4 more
2021PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system.
H. Erxleben, M. K. Manion, D. Hockenbery, L. Scampavia +1 more
2004In Analysis23 citations
Semantic Scholar
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu +25 more
2023Cell Research21 citations Open access
Semantic Scholar
A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons
BanuPriya Sridharan, Christopher Hubbs, N. Llamosas, Murat Kilinc +6 more
2019Scientific Reports20 citations Open access
Semantic Scholar
Elemene sensitizes pancreatic cancer cells to bortezomib by enhancing proteasome inhibition via molecular patch mechanism
Shurong Hou, Zhenzhen Li, Xiao-Ling Chen, Wen Wang +6 more
2023Signal Transduction and Targeted Therapy18 citations Open access
Semantic Scholar
Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and β
Franck Madoux, Claudia Tredup, T. Spicer, L. Scampavia +5 more
2014Biopolymers18 citations Open access
Semantic Scholar
Automated Method, Based on Micro-Sequential Injection, for the Study of Enzyme Kinetics and Inhibition
Yan Chen, Andrea D Carroll, L. Scampavia, J. Ruzicka
2006Analytical Sciences18 citations Open access
Semantic Scholar
An unbiased high‐throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer
C. Pan, Yuka Otsuka, BanuPriya Sridharan, Melissa Woo +11 more
2019bioRxiv17 citations Open access
Semantic Scholar
Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders
T. Spicer, Christopher Hubbs, Thomas Vaissiere, Deanna R Collia +14 more
2017Molecular Neuropsychiatry17 citations Open access
Semantic Scholar
Identification of Potential Pharmacoperones Capable of Rescuing the Functionality of Misfolded Vasopressin 2 Receptor Involved in Nephrogenic Diabetes Insipidus
Emery Smith, J. Janovick, Thomas D. Bannister, Justin Shumate +3 more
2016Journal of biomolecular screening17 citations Open access
Semantic Scholar
IoT for Real-Time Measurement of High-Throughput Liquid Dispensing in Laboratory Environments
Justin Shumate, Pierre Baillargeon, T. Spicer, L. Scampavia
2018SLAS technology16 citations Open access
Semantic Scholar
Drug Library Screening for the Identification of Ionophores That Correct the Mistrafficking Disorder Associated with Oxalosis Kidney Disease
Shurong Hou, Franck Madoux, L. Scampavia, J. Janovick +2 more
2017SLAS discovery : advancing life sciences R & D16 citations Open access
Semantic Scholar
Automated affinity chromatography measurements of compound mixtures using a lab-on-valve apparatus coupled to electrospray ionization mass spectrometry.
Yuko Ogata, L. Scampavia, T. L. Carter, E. Fan +1 more
2004Analytical Biochemistry16 citations
Semantic Scholar
An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors
E. Jambrina, R. Cerne, Emery Smith, L. Scampavia +10 more
2016Journal of biomolecular screening14 citations Open access
Semantic Scholar
A Phenotypic High Throughput Screening Assay for the Identification of Pharmacoperones for the Gonadotropin Releasing Hormone Receptor
P. Conn, Emery Smith, T. Spicer, P. Chase +2 more
2014Assay and drug development technologies14 citations Open access
Semantic Scholar
Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High Throughput Screening
T. Spicer, V. Fernandez-Vega, P. Chase, L. Scampavia +13 more
2014Journal of biomolecular screening14 citations Open access
Semantic Scholar
Pharmacoperone rescue of vasopressin 2 receptor mutants reveals unexpected constitutive activity and coupling bias
J. Janovick, Timothy P. Spicer, Thomas D. Bannister, L. Scampavia +1 more
2017PLoS ONE13 citations Open access
Semantic Scholar
In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma
Robin Rajan, V. Fernandez-Vega, J. Sperry, J. Nakashima +11 more
2023Cancers12 citations Open access
Semantic Scholar
Protocol for 3D Screening of Lung Cancer Spheroids using Natural Products
V. F. Vega, Dong Yang, L. O. Jordán, Fei Ye +9 more
2023SLAS discovery : advancing life sciences R & D12 citations Open access
Semantic Scholar
Screening for Modulators of Autism Spectrum Disorder Using Induced Human Neurons.
S. Rao, A. Kostić, Pierre Baillargeon, V. Fernandez-Vega +6 more
2022SLAS discovery : advancing life sciences R & D12 citations Open access
Semantic Scholar
Receptor Antagonism/Agonism Can Be Uncoupled from Pharmacoperone Activity
J. Janovick, Timothy P. Spicer, Emery Smith, Thomas D. Bannister +3 more
2016Molecular and Cellular Endocrinology12 citations Open access
Semantic Scholar

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