Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Steven J. Brown · SciRah

Researcher profile · Semantic Scholar

Steven J. Brown

Share profile

Steven J. Brown — researcher profile on SciRah

h-index: 36
Works: 280
Citations: 5,480

Most-cited papers

Crohn's disease management after intestinal resection: a randomised trial.
P. De Cruz, M. Kamm, A. Hamilton, K. Ritchie +24 more
2015The Lancet562 citations
Semantic Scholar
Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection.
Mette Julsgaard, L. A. Christensen, P. Gibson, R. Gearry +19 more
2016Gastroenterology309 citations Open access
Semantic Scholar
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation
L. Plate, Christina B. Cooley, John J. Chen, Ryan J. Paxman +14 more
2016eLife216 citations Open access
Semantic Scholar
A global map of lipid-binding proteins and their ligandability in cells
M. Niphakis, Kenneth M. Lum, A. Cognetta, Bruno E. Correia +7 more
2015Cell215 citations Open access
Semantic Scholar
Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation
J. Johnson, Mahalakshmi Ramadass, Jing He, Steven J. Brown +6 more
2016Journal of Biological Chemistry97 citations Open access
Semantic Scholar
Chemical proteomic profiling of human methyltransferases
Benjamin D. Horning, R. Suciu, Darian A Ghadiri, O. Ulanovskaya +6 more
2016Journal of the American Chemical Society76 citations Open access
Semantic Scholar
Stabilization of amyloidogenic immunoglobulin light chains by small molecules
G. Morgan, Nicholas L. Yan, D. E. Mortenson, E. Rennella +12 more
2019Proceedings of the National Academy of Sciences of the United States of America69 citations Open access
Semantic Scholar
Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo
Daisuke Ogasawara, Taka Aki-Ichu, Vincent F. Vartabedian, J. Benthuysen +9 more
2018Nature Chemical Biology65 citations Open access
Semantic Scholar
Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction
M. Sanna, K. Vincent, Emanuela Repetto, N. Nguyen +11 more
2016Molecular Pharmacology52 citations Open access
Semantic Scholar
Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)
M. Guerrero, M. Urbano, Eun-Kyong Kim, A. Gamo +10 more
2019Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
A selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival
J. Chang, A. Zuhl, A. Speers, S. Niessen +15 more
2015ACS Chemical Biology46 citations Open access
Semantic Scholar
Infliximab, adalimumab and vedolizumab concentrations across pregnancy and vedolizumab concentrations in infants following intrauterine exposure
E. Flanagan, P. Gibson, E. Wright, G. Moore +17 more
2020Alimentary Pharmacology and Therapeutics45 citations
Semantic Scholar
Identification of Potent Inhibitors of the Trypanosoma brucei Methionyl-tRNA Synthetase via High Throughput Orthogonal Screening
Laura Pedró-Rosa, Frederick S. Buckner, Ranae M. Ranade, C. Eberhart +12 more
2014Journal of biomolecular screening38 citations Open access
Semantic Scholar
Effect of intestinal resection on quality of life in Crohn's disease.
E. Wright, M. Kamm, P. De Cruz, A. Hamilton +25 more
2015Journal of Crohn's & Colitis35 citations
Semantic Scholar
Maternal thiopurine metabolism during pregnancy in inflammatory bowel disease and clearance of thiopurine metabolites and outcomes in exposed neonates
E. Flanagan, E. Wright, W. Hardikar, M. Sparrow +11 more
2021Alimentary Pharmacology and Therapeutics34 citations Open access
Semantic Scholar
Anti-TNF Therapy in Pregnant Women With Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes.
Mette Julsgaard, C. Hvas, R. Gearry, P. Gibson +26 more
2019Inflammatory Bowel Diseases32 citations
Semantic Scholar
Serologic antibodies in relation to outcome in postoperative Crohn's disease
A. Hamilton, M. Kamm, P. De Cruz, E. Wright +20 more
2017Journal of Gastroenterology and Hepatology32 citations Open access
Semantic Scholar
Design, Synthesis, and In Vitro and In Vivo Evaluation of an 18F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P1) PET Tracer
Adam J Rosenberg, Hui Liu, Hongjun Jin, Xu-Yi Yue +3 more
2016Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
The Scripps Molecular Screening Center and Translation Research Institute
Pierre Baillargeon, V. Fernandez-Vega, BanuPriya Sridharan, Steven J. Brown +5 more
2019SLAS discovery : advancing life sciences R & D27 citations Open access
Semantic Scholar
Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)
Alexander Adibekian, Brent R. Martin, J. Chang, Ku-Lung Hsu +10 more
201427 citations
Semantic Scholar
Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn’s Disease
E. Wright, M. Kamm, P. De Cruz, A. Hamilton +21 more
2018Journal of Crohn's & Colitis24 citations Open access
Semantic Scholar
Magnetic resonance enterography for predicting the clinical course of Crohn's disease strictures
J. Schulberg, E. Wright, Bronte A. Holt, T. Sutherland +9 more
2019Journal of Gastroenterology and Hepatology23 citations Open access
Semantic Scholar
Thiopurine metabolite testing in inflammatory bowel disease
Rimma Goldberg, G. Moore, G. Cunningham, J. Schulberg +6 more
2016Journal of Gastroenterology and Hepatology20 citations
Semantic Scholar
Small‐Molecule Procaspase Activators Identified Using Fluorescence Polarization
C. Vickers, Gonzalo E. González-Páez, Jeffrey C. Umotoy, Charmagne Cayanan-Garrett +2 more
2013ChemBioChem18 citations
Semantic Scholar
A Single Educational Intervention Improves Pregnancy-Related Knowledge and Emotional Health Among Women With IBD Who Are Pregnant or Wish to Conceive.
E. Flanagan, E. Wright, M. Sparrow, G. Moore +13 more
2021Inflammatory Bowel Diseases17 citations
Semantic Scholar
Cost-effectiveness of Crohn's disease post-operative care.
E. Wright, M. Kamm, Peter Dr Cruz, A. Hamilton +6 more
2016World Journal of Gastroenterology12 citations Open access
Semantic Scholar
Long‐term outcomes of perianal fistulizing Crohn's disease in the biologic era
Tanya Lee, M. Kamm, S. Bell, M. Lust +11 more
2020JGH Open9 citations Open access
Semantic Scholar
Optimization and characterization of an opioid kappa receptor (OPRK1) antagonist
M. Guerrero, Mariagela Urbano, Steven J. Brown, Charmagne S. Cayanan +5 more
20148 citations
Semantic Scholar
Optimization and characterization of a triazole urea inhibitor for alpha/beta hydrolase domain-containing protein 11 (ABHD11): anti-probe for LYPLA1/LYPLA2 dual inhibitor ML211
Alexander Adibekian, Ku-Lung Hsu, A. Speers, Steven J. Brown +6 more
20138 citations
Semantic Scholar
Probe Development Efforts to Identify Novel Inhibitors of ABHD10
Andrea M. Zuhl, J. Mohr, A. Speers, D. Bachovchin +9 more
20136 citations
Semantic Scholar
Optimization and characterization of a triazole urea inhibitor for diacylglycerol lipase beta (DAGL-β)
Ku-Lung Hsu, K. Tsuboi, A. Speers, Steven J. Brown +6 more
20136 citations
Semantic Scholar
312 The First Validated Post-Operative Endoscopic Crohns Disease Index: The POCER Index. Identification of Key Endoscopic Prognostic Factors
P. De Cruz, M. Kamm, A. Hamilton, K. Ritchie +22 more
20165 citations
Semantic Scholar
An in Vivo Active Carbamate-based Dual Inhibitor of Lysophospholipase 1 (LYPLA1) and Lysophospholipase 2 (LYPLA2)
Jonathan J. Hulce, C. Joslyn, A. Speers, Steven J. Brown +6 more
20144 citations
Semantic Scholar
Su1318 Intestinal Resection in Crohn's Disease Is Associated With Significant and Durable Improvement in Health Related Quality of Life Although to a Lesser Extent in Women and Smokers. Results From the POCER Study
E. Wright, P. De Cruz, M. Kamm, A. Hamilton +27 more
20144 citations Open access
Semantic Scholar
Fluorometric High-Throughput Screening Assay for Secreted Phospholipases A2 Using Phospholipid Vesicles
Heather Ewing, V. Fernandez-Vega, T. Spicer, P. Chase +8 more
2016Journal of biomolecular screening3 citations Open access
Semantic Scholar
Bitopic S1P 3 Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P 3 Regulation of Mouse Cardiac Conduction
M. Sanna, K. Vincent, Emanuela Repetto, N. Nguyen +12 more
20153 citations
Semantic Scholar
Optimization and characterization of a triazole urea inhibitor for platelet-activating factor acetylhydrolase type 2 (PAFAH2)
Alexander Adibekian, Ku-Lung Hsu, A. Speers, Elizabeth S. Monillas +8 more
20133 citations
Semantic Scholar
Munc13-4–STX7 inhibitors impair endosomal TLR activation and systemic inflammation
Jennifer L. Johnson, Elsa Meneses-Salas, A. Shukla, Binchu V. Shaji +12 more
2026Nature Chemical Biology2 citations Open access
Semantic Scholar
597 Serological Antibodies for the Prediction of Post-Operative Recurrent Crohn's Disease Results From the POCER Study
A. Hamilton, M. Kamm, Fabiyola Selvaraj, F. Princen +28 more
20152 citations
Semantic Scholar
Optimization and characterization of an antagonist for vasopressin 1a (V1a) receptor
G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more
20142 citations
Semantic Scholar
998 Faecal Calprotectin Is Superior to Faecal Lactoferrin and S100A12 As a Surrogate Marker for Post-Operative Crohn's Disease Endoscopic Recurrence. Prospective Longitudinal Endoscopic Validation. Results From the POCER Study
E. Wright, P. De Cruz, M. Kamm, A. Hamilton +28 more
20142 citations
Semantic Scholar
Optimization and characterization of a carbamate inhibitor for plasma platelet-activating factor acetylhydrolase (pPAFAH)
Joseph M G Nagano, Ku-Lung Hsu, A. Speers, Steven J. Brown +7 more
20141 citations
Semantic Scholar
Author response: Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation
L. Plate, Christina B. Cooley, John J. Chen, Ryan J. Paxman +14 more
20160 citations Open access
Semantic Scholar
Sa1269 Adjunctive Allopurinol in Azathioprine/6-Mercaptopurine Non-Responders Optimises 6-Thioguanine Nucleotide Production and Improves Clinical Outcomes in Inflammatory Bowel Disease: The Prospective, Multicentre, Double Blind, Dose-Ranging AAA Study
A. Friedman, Steven J. Brown, P. Bampton, M. Barclay +7 more
20150 citations Open access
Semantic Scholar
Tu1289 Preventing Crohn's Disease Recurrence After Resection With Adalimumab: Role of Drug and Anti-Drug Antibody Levels
E. Wright, M. Kamm, Fabiyola Selvaraj, F. Princen +28 more
20150 citations Open access
Semantic Scholar
Sa1143 Need for Recurrent Resection and Complex Phenotype Are Associated With a Specific Antibody Signature in Crohn's Disease Patients Undergoing Resection; Smoking Is Not Associated With Prevalent Antibodies; Prognostic and Mechanistic Implications
A. Hamilton, M. Kamm, Fabiyola Selvaraj, F. Princen +28 more
20150 citations
Semantic Scholar
Figure 3, LC-MS of ML389
G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more
20140 citations
Semantic Scholar
Table S1, Activity of cherry-picked HTS hits against pPAFAH as assessed by gel-based competitive ABPP (AID 588474)
Joseph M G Nagano, Ku-Lung Hsu, A. Speers, Steven J. Brown +7 more
20140 citations
Semantic Scholar
Figure 1, LC/MS analysis of ML350
M. Guerrero, Mariagela Urbano, Steven J. Brown, Charmagne S. Cayanan +5 more
20140 citations
Semantic Scholar
Table S3, Serine Hydrolase (SH) Abbreviations and Names
Joseph M G Nagano, Ku-Lung Hsu, A. Speers, Steven J. Brown +7 more
20140 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

H. Rosen×27
Invite
H. Rosen — researcher profile on SciRah
S. Bell×19
Invite
S. Bell — researcher profile on SciRah
M. Kamm×18
Invite
M. Kamm — researcher profile on SciRah
W. Connell×18
Invite
W. Connell — researcher profile on SciRah

×16

Invite

P. Hodder — researcher profile on SciRah

Invite

P. Gibson — researcher profile on SciRah

Invite

B. Cravatt — researcher profile on SciRah

Invite

T. Spicer — researcher profile on SciRah

Invite

E. Wright — researcher profile on SciRah

Invite

P. De Cruz — researcher profile on SciRah

Invite

J. Andrews — researcher profile on SciRah

Invite

M. Sparrow — researcher profile on SciRah