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Melinda M. Mulvihill · SciRah

Researcher profile · Semantic Scholar

Melinda M. Mulvihill

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Melinda M. Mulvihill — researcher profile on SciRah

h-index: 19
Works: 35
Citations: 1,943

Most-cited papers

Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity
D. I. Benjamin, A. Cozzo, Xiaodan Ji, L. Roberts +4 more
2013Proceedings of the National Academy of Sciences of the United States of America232 citations Open access
Semantic Scholar
Therapeutic Potential of Monoacylglycerol Lipase Inhibitors
Melinda M. Mulvihill, D. Nomura
2012Life Science186 citations Open access
Semantic Scholar
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity
Thomas H. Pillow, Pragya Adhikari, R. Blake, Jinhua Chen +28 more
2019ChemMedChem179 citations
Semantic Scholar
Cancer Cells Incorporate and Remodel Exogenous Palmitate into Structural and Oncogenic Signaling Lipids
Sharon M. Louie, L. Roberts, Melinda M. Mulvihill, K. Luo +1 more
2013Biochimica et Biophysica Acta149 citations Open access
Semantic Scholar
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy.
P. Dragovich, Thomas H. Pillow, R. Blake, J. Sadowsky +33 more
2021Journal of Medicinal Chemistry139 citations
Semantic Scholar
Monoacylglycerol Lipase Controls Endocannabinoid and Eicosanoid Signaling and Hepatic Injury in Mice
Zong-Xian Cao, Melinda M. Mulvihill, P. Mukhopadhyay, Huan Xu +7 more
2013Gastroenterology139 citations Open access
Semantic Scholar
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties.
P. Dragovich, Thomas H. Pillow, R. Blake, J. Sadowsky +33 more
2021Journal of Medicinal Chemistry119 citations
Semantic Scholar
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.
Tatiana Goncharov, Stefanie Hedayati, Melinda M. Mulvihill, A. Izrael-Tomasevic +11 more
2018Molecules and Cells112 citations Open access
Semantic Scholar
Organophosphorus Flame Retardants Inhibit Specific Liver Carboxylesterases and Cause Serum Hypertriglyceridemia
Patrick J. Morris, Daniel A. Medina-Cleghorn, A. Heslin, Sarah M. King +4 more
2014ACS Chemical Biology99 citations Open access
Semantic Scholar
Ski regulates Hippo and TAZ signaling to suppress breast cancer progression
J. Rashidian, E. le Scolan, Xiaodan Ji, Qingwei Zhu +3 more
2015Science Signaling67 citations Open access
Semantic Scholar
Metabolic Profiling Reveals PAFAH1B3 as a Critical Driver of Breast Cancer Pathogenicity
Melinda M. Mulvihill, D. I. Benjamin, Xiaodan Ji, E. le Scolan +7 more
2014Chemistry and Biology57 citations Open access
Semantic Scholar
Inositol Phosphate Recycling Regulates Glycolytic and Lipid Metabolism That Drives Cancer Aggressiveness
D. I. Benjamin, Sharon M. Louie, Melinda M. Mulvihill, Rebecca A. Kohnz +9 more
2014ACS Chemical Biology51 citations Open access
Semantic Scholar
Quantitative Determination of Protein-Ligand Affinity by Size Exclusion Chromatography Directly Coupled to High-Resolution Native Mass Spectrometry.
Chengfeng Ren, A. Bailey, Erica C. Vanderporten, A. Oh +6 more
2018Analytical Chemistry48 citations
Semantic Scholar
A selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival
J. Chang, A. Zuhl, A. Speers, S. Niessen +15 more
2015ACS Chemical Biology46 citations Open access
Semantic Scholar
Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer
Rebecca A. Kohnz, Melinda M. Mulvihill, J. Chang, Ku-Lung Hsu +5 more
2015ACS Chemical Biology39 citations Open access
Semantic Scholar
High-Throughput Kinetic Characterization of Irreversible Covalent Inhibitors of KRASG12C by Intact Protein MS and Targeted MRM.
K. Li, J. Quinn, Matthew J. Saabye, Jesus F. Salcido Guerrero +9 more
2022Analytical Chemistry36 citations
Semantic Scholar
Native Mass Spectrometry for the Study of PROTAC GNE‐987‐Containing Ternary Complexes
Louise M. Sternicki, J. Nonomiya, Miao-Miao Liu, Melinda M. Mulvihill +1 more
2021ChemMedChem35 citations Open access
Semantic Scholar
Multidimensional Profiling Platforms Reveal Metabolic Dysregulation caused by Organophosphorus Pesticides
Daniel A. Medina-Cleghorn, A. Heslin, Patrick J. Morris, Melinda M. Mulvihill +1 more
2013ACS Chemical Biology28 citations Open access
Semantic Scholar
Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)
I. Devries, Rachel J. Hampton-Smith, Melinda M. Mulvihill, V. Alverdi +2 more
2010FEBS Letters25 citations Open access
Semantic Scholar
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein.
W. den Besten, K. Verma, Sayumi Yamazoe, N. Blaquiere +12 more
2021Journal of the American Chemical Society19 citations
Semantic Scholar
Membrane-induced peptide structural changes monitored by infrared and circular dichroism spectroscopy.
Daniel J Laird, Melinda M. Mulvihill, Jennifer A. Whiles Lillig
2009Biophysical Chemistry19 citations
Semantic Scholar
A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
M. Steffek, E. Helgason, N. Popovych, L. Rougé +22 more
2022Biochemistry18 citations Open access
Semantic Scholar
Determination of Affinity and Residence Time of Potent Drug-Target Complexes by Label-free Biosensing.
J. Quinn, Keith E Pitts, M. Steffek, Melinda M. Mulvihill
2018Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Small-Molecule Lead-Finding Trends across the Roche and Genentech Research Organizations.
P. Dragovich, W. Haap, Melinda M. Mulvihill, Jean-Marc Plancher +1 more
2022Journal of Medicinal Chemistry16 citations
Semantic Scholar
Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors
C. Davies, A. Oh, R. Mroue, M. Steffek +23 more
2022Nature Biotechnology16 citations Open access
Semantic Scholar
Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability.
Hao Wu, Jeremy Murray, Noriko Ishisoko, Alexandra Frommlet +8 more
2024Journal of Medicinal Chemistry11 citations Open access
Semantic Scholar
Metabolomic strategies to map functions of metabolic pathways.
Melinda M. Mulvihill, D. Nomura
2014American Journal of Physiology. Endocrinology and Metabolism11 citations Open access
Semantic Scholar
Front Cover: Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity (ChemMedChem 1/2020)
Thomas H. Pillow, Pragya Adhikari, R. Blake, Jinhua Chen +28 more
2020ChemMedChem9 citations
Semantic Scholar
Covalent Library Screening by Targeted Mass Spectrometry for Rapid Binding Site Identification.
J. Nonomiya, K. Li, Brett M. Babin, Melinda M. Mulvihill
2023Analytical Chemistry8 citations
Semantic Scholar
Protein Interactions between Fe65, the LDL receptor-related protein and the amyloid precursor protein
Melinda M. Mulvihill, M. Guttman, E. Komives
2011Biochemistry8 citations Open access
Semantic Scholar
Unlocking latent kinetic information from label-free binding
J. Quinn, M. Steffek, John M. Bruning, Alexandra Frommlet +1 more
2019Scientific Reports4 citations Open access
Semantic Scholar
Combining Fundamental Kinetics and Standard Alkylation Assays to Prioritize Lead-Like KRAS G12C Inhibitors
Alexandra Frommlet, Lan K Nguyen, Matt Saabye, Nicholas F Endres +2 more
2024ACS Omega3 citations Open access
Semantic Scholar
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases
Anna Shemorry, W. den Besten, Melinda M. Mulvihill, Curt J. Essenburg +18 more
2024bioRxiv1 citations
Semantic Scholar
Correction to “Combining Fundamental Kinetics and Standard Alkylation Assays to Prioritize Lead-like KRAS G12C Inhibitors”
Alexandra Frommlet, Lan K Nguyen, Matt Saabye, Nicholas F Endres +2 more
2025ACS Omega0 citations Open access
Semantic Scholar
Post-translational modifications in intrinsically disordered regions and their contribution to protein- protein interactions
Melinda M. Mulvihill
20110 citations
Semantic Scholar

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