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R. Mroue · SciRah

Researcher profile · Semantic Scholar

R. Mroue

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R. Mroue — researcher profile on SciRah

h-index: 11
Works: 26
Citations: 1,387

Most-cited papers

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors
A. Daemen, David A. Peterson, Nisebita Sahu, R. McCord +18 more
2015Proceedings of the National Academy of Sciences of the United States of America352 citations Open access
Semantic Scholar
Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia
J. Alcaraz, Ren Xu, H. Mori, C. M. Nelson +6 more
2008EMBO Journal206 citations Open access
Semantic Scholar
Coherent angular motion in the establishment of multicellular architecture of glandular tissues
Kandice Tanner, H. Mori, R. Mroue, A. Bruni-Cardoso +1 more
2012Proceedings of the National Academy of Sciences of the United States of America197 citations Open access
Semantic Scholar
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
Thijs J. Hagenbeek, J. Zbieg, M. Hafner, R. Mroue +38 more
2023Nature Cancer189 citations Open access
Semantic Scholar
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence In Cancer
M. R. Burgess, E. Hwang, R. Mroue, C. Bielski +18 more
2017Cell163 citations Open access
Semantic Scholar
Three-Dimensional Cultures of Mouse Mammary Epithelial Cells
R. Mroue, M. Bissell
2013Methods in molecular biology98 citations Open access
Semantic Scholar
Heterocellular interaction enhances recruitment of alpha and beta-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependant differentiation of mammary epithelial cells.
R. Talhouk, R. Mroue, Mayssa H. Mokalled, Lina Abi-Mosleh +5 more
2008Experimental Cell Research61 citations
Semantic Scholar
Connexins and the gap in context.
R. Mroue, M. El-Sabban, R. Talhouk
2011Integrative Biology35 citations
Semantic Scholar
Asymmetric Expression of Connexins between luminal epithelial- and myoepithelial- cells is Essential for Contractile Function of the Mammary Gland
R. Mroue, J. L. Inman, J. D. Mott, I. Budunova +1 more
2014Developmental Biology32 citations Open access
Semantic Scholar
Correction: Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1+/- Mice
R. Mroue, Brian W. Huang, S. Braunstein, Ari J. Firestone +1 more
2015PLoS Genetics17 citations Open access
Semantic Scholar
Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors
C. Davies, A. Oh, R. Mroue, M. Steffek +23 more
2022Nature Biotechnology16 citations Open access
Semantic Scholar
Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C
Nicholas F. Endres, S. Do, R. Mroue, Jack A. Terrett +48 more
2026Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues
Taylur P. Ma, A. Izrael-Tomasevic, R. Mroue, Hanna G. Budayeva +6 more
2023Journal of Proteome Research7 citations Open access
Semantic Scholar
Discovery and Optimization of a Potent, Efficacious, and Brain-Penetrant Inhibitor of KRAS G12C.
Matthew L. Landry, Sushant Malhotra, Maureen H. Beresini, Connie Chan +29 more
2026Journal of Medicinal Chemistry5 citations
Semantic Scholar
Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma
Andrew Goetz, Frances Shanahan, Logan Brooks, Eva Lin +9 more
2024Cancers3 citations Open access
Semantic Scholar
Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1+/- Mice
R. Mroue, Brian W. Huang, S. Braunstein, Ari J. Firestone +1 more
2015PLoS Genetics3 citations Open access
Semantic Scholar
CLAMPs allow single cell tracking of KRASG12C inhibition and endow druggability to KRAS mutants
M. Evangelista, C. Davies, A. Oh, R. Mroue +16 more
20211 citations Open access
Semantic Scholar
Molecular mechanism of HUWE1-HAPSTR1-USP7-mediated ubiquitin chain amplification on nuclear proteins.
S. Yatskevich, Jugal Mohapatra, R. Mroue, Lilian Phu +9 more
2026Molecules and Cells0 citations
Semantic Scholar
Computational modeling of drug response identifies mutant-specific constraints for dosing panRAF and MEK inhibitors in melanoma
Andrew Goetz, Frances Shanahan, Logan Brooks, Eva Lin +9 more
2024bioRxiv0 citations Open access
Semantic Scholar
Abstract 68: Tumor operational signaling pathways in an Nf1 mutant mouse model system
S. Braunstein, R. Mroue, Brian W. Huang, Sourav Bandyopadhyay +1 more
20140 citations
Semantic Scholar
Operational Signaling Pathways in Radiation-Induced Tumors
S. Braunstein, R. Mroue, Brian W. Huang, Sourav Bandyopadhyay +1 more
20130 citations Open access
Semantic Scholar
Asymmetric Expression/ Distribution of Connexins is Essential for Contractile Function in the Mammary Gland
R. Mroue
20110 citations
Semantic Scholar
Cell Communication and Signaling
Hashem A. Dbouk, R. Mroue, M. El-Sabban, R. Talhouk +3 more
20090 citations
Semantic Scholar
Connexins: a myriad of functions extending beyond assembly of gap junction channels
Hashem A. Dbouk, R. Mroue, M. El-Sabban, R. Talhouk
2009Cell Communication and Signaling0 citations Open access
Semantic Scholar
Role of PI3 Kinase Signaling Pathways in Polarity Development of Human Mammary Epithelial Cells Grown in Three-Dimensional Extracellular Matrix
R. Mroue
20060 citations
Semantic Scholar
A translational QSP model to characterize the preclinical pharmacodynamics of combining a KRAS G12C inhibitor with a SHP2 inhibitor
Dan Lu, R. Sheehan, Nicole M. Sodir, R. Mroue +17 more
Proceedings of the American Conference of Pharmacometrics 20240 citations Open access
Semantic Scholar

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