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A. Zirlik · SciRah

Researcher profile · Semantic Scholar

A. Zirlik

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A. Zirlik — researcher profile on SciRah

h-index: 38
Works: 196
Citations: 5,035

Most-cited papers

Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100–Reactive CD4+ T-Regulatory Cells
D. Wolf, T. Gerhardt, H. Winkels, N. Michel +29 more
2020Circulation141 citations Open access
Semantic Scholar
Mitochondrial Mechanisms in Diabetic Cardiomyopathy
J. Gollmer, A. Zirlik, H. Bugger
2020Diabetes & Metabolism Journal114 citations Open access
Semantic Scholar
CD40L and Its Receptors in Atherothrombosis—An Update
N. Michel, A. Zirlik, D. Wolf
2017Frontiers in Cardiovascular Medicine111 citations Open access
Semantic Scholar
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense
D. Wolf, N. Anto-Michel, H. Blankenbach, Ansgar Wiedemann +28 more
2018Nature Communications98 citations Open access
Semantic Scholar
P2X7 Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice
P. Stachon, A. Heidenreich, J. Merz, I. Hilgendorf +12 more
2017Circulation92 citations Open access
Semantic Scholar
Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
J. Pennig, P. Scherrer, M. Gissler, N. Anto-Michel +11 more
2019Scientific Reports70 citations Open access
Semantic Scholar
Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice
P. Stachon, Serjosha Geis, A. Peikert, A. Heidenreich +17 more
2016Arteriosclerosis, Thrombosis and Vascular Biology69 citations Open access
Semantic Scholar
Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor
Debapriya Basu, Yunying Hu, L. Huggins, A. Mullick +10 more
2018Circulation Research58 citations Open access
Semantic Scholar
Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
C. Koentges, M. C. Cimolai, K. Pfeil, D. Wolf +10 more
2019Journal of Molecular and Cellular Cardiology57 citations
Semantic Scholar
Pathogenic Role of Air Pollution Particulate Matter in Cardiometabolic Disease: Evidence from Mice and Humans
T. Marchini, A. Zirlik, D. Wolf
2020Antioxidants and Redox Signaling55 citations Open access
Semantic Scholar
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering
C. Härdtner, J. Kornemann, K. Krebs, C. Ehlert +25 more
2020Basic Research in Cardiology52 citations Open access
Semantic Scholar
Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome
J. Merz, P. Albrecht, S. von Garlen, I. Ahmed +15 more
2018Basic Research in Cardiology46 citations
Semantic Scholar
Gene Expression Analysis to Identify Mechanisms Underlying Heart Failure Susceptibility in Mice and Humans
C. Koentges, Mark E. Pepin, Carolyn Müsse, K. Pfeil +10 more
2017Basic Research in Cardiology44 citations Open access
Semantic Scholar
Real-time magnetic resonance imaging – guided coronary intervention in a porcine model
T. Heidt, S. Reiss, A. Krafft, A. Özen +15 more
2019Scientific Reports35 citations Open access
Semantic Scholar
Sex-Specific Differences in Outcome of Transcatheter or Surgical Aortic Valve Replacement.
K. Kaier, C. von zur Mühlen, A. Zirlik, C. Schmoor +7 more
2018Canadian Journal of Cardiology33 citations
Semantic Scholar
Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile
J. Merz, A. Nettesheim, S. von Garlen, P. Albrecht +17 more
2021Purinergic Signalling Purinergic Signalling31 citations Open access
Semantic Scholar
Cellular Heterogeneity of the Heart
N. Anto Michel, Senka (Ljubojevic) Holzer, H. Bugger, A. Zirlik
2022Frontiers in Cardiovascular Medicine27 citations Open access
Semantic Scholar
Risk factors and outcome of postoperative delirium after transcatheter aortic valve replacement
P. Stachon, K. Kaier, A. Zirlik, J. Reinöhl +6 more
2018Clinical Research in Cardiology27 citations
Semantic Scholar
Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice
J. Leipner, T. Dederichs, A. von Ehr, S. Rauterberg +14 more
2021Molecular Metabolism26 citations Open access
Semantic Scholar
Transcatheter Aortic Valve Replacement: The New Standard in Patients With Previous Coronary Bypass Grafting?
J. Reinöhl, K. Kaier, H. Reinecke, L. Frankenstein +5 more
2016JACC: Cardiovascular Interventions25 citations Open access
Semantic Scholar
Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice
M. Gissler, P. Scherrer, N. Anto-Michel, J. Pennig +18 more
2021Thrombosis and Haemostasis23 citations Open access
Semantic Scholar
Risk‐Adjusted Comparison of In‐Hospital Outcomes of Transcatheter and Surgical Aortic Valve Replacement
P. Stachon, K. Kaier, A. Zirlik, W. Bothe +4 more
2019Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease23 citations Open access
Semantic Scholar
Learning Curves Among All Patients Undergoing Transcatheter Aortic Valve Implantation in Germany: A Retrospective Observational Study.
K. Kaier, H. Reinecke, C. Schmoor, L. Frankenstein +6 more
2017International Journal of Cardiology23 citations
Semantic Scholar
Nationwide outcomes of aortic valve replacement for pure aortic regurgitation in Germany 2008–2015
P. Stachon, K. Kaier, T. Heidt, W. Bothe +4 more
2020Catheterization and cardiovascular interventions21 citations
Semantic Scholar
Inflammatory Pathways Regulated by Tumor-Necrosis Receptor Associated Factor 1 Protect from Metabolic Consequences in Diet-Induced Obesity
Nathaly Anto Michel, C. Colberg, Konrad Buscher, Björn Sommer +20 more
2018Circulation Research21 citations Open access
Semantic Scholar
Impact of pulmonary hypertension on in-hospital outcome after surgical or transcatheter aortic valve replacement.
Anja Gutmann, K. Kaier, H. Reinecke, L. Frankenstein +7 more
2017EuroIntervention21 citations
Semantic Scholar
Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS
L. Heger, M. Hortmann, M. Albrecht, C. Colberg +7 more
2019PLoS ONE17 citations Open access
Semantic Scholar
Outcomes of transcatheter aortic valve implantations in high-volume or low-volume centres in Germany
V. Oettinger, K. Kaier, T. Heidt, Markus Hortmann +6 more
2020Heart14 citations
Semantic Scholar
Coronary magnetic resonance imaging after routine implantation of bioresorbable vascular scaffolds allows non-invasive evaluation of vascular patency
C. von zur Mühlen, S. Reiss, A. Krafft, L. Besch +15 more
2018PLoS ONE14 citations Open access
Semantic Scholar
P2X4 deficiency reduces atherosclerosis and plaque inflammation in mice
A. Peikert, S. König, D. Suchanek, K. Rofa +19 more
2022Scientific Reports13 citations Open access
Semantic Scholar
Estimating the additional costs per life saved due to transcatheter aortic valve replacement: a secondary data analysis of electronic health records in Germany
K. Kaier, C. von zur Mühlen, A. Zirlik, W. Bothe +4 more
2019European Journal of Health Economics12 citations
Semantic Scholar
The impact of post-procedural complications on reimbursement, length of stay and mechanical ventilation among patients undergoing transcatheter aortic valve implantation in Germany
K. Kaier, H. Reinecke, H. Naci, L. Frankenstein +6 more
2018European Journal of Health Economics11 citations Open access
Semantic Scholar
Towards a cardiac allocation score: a retrospective calculation for 73 patients from a German transplant center
S. Claes, M. Berchtold-Herz, Qian Zhou, G. Trummer +5 more
2017Journal of Cardiothoracic Surgery11 citations Open access
Semantic Scholar
Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice
M. Gissler, N. Anto-Michel, J. Pennig, P. Scherrer +28 more
2021Arteriosclerosis, Thrombosis and Vascular Biology10 citations Open access
Semantic Scholar
A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques.
A. Maier, Patricia Plaza-Heck, Fabian Meixner, F. Guenther +13 more
2017Atherosclerosis9 citations
Semantic Scholar
Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1
Mark E. Pepin, C. Koentges, K. Pfeil, J. Gollmer +12 more
2019Frontiers in Endocrinology8 citations Open access
Semantic Scholar
Circulating Autoantibodies Recognizing Immunodominant Epitopes From Human Apolipoprotein B Associate With Cardiometabolic Risk Factors, but Not With Atherosclerotic Disease
T. Marchini, S. Malchow, L. Cáceres, Abed Al Hadi El Rabih +17 more
2022Frontiers in Cardiovascular Medicine7 citations Open access
Semantic Scholar
Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis
F. Günther, T. Heidt, M. Kramer, E. Khanicheh +11 more
2017Scientific Reports7 citations Open access
Semantic Scholar
Severe eosinophilic myocarditis associated with modafinil in a patient with normal peripheral eosinophil count
M. Bäuml, J. Udi, K. Klingel, C. Bode +4 more
2019Clinical Research in Cardiology6 citations
Semantic Scholar
Publisher Correction: Real-time magnetic resonance imaging – guided coronary intervention in a porcine model
T. Heidt, S. Reiss, A. Krafft, A. Özen +15 more
2019Scientific Reports6 citations Open access
Semantic Scholar
Endothelial CD40L serves as a pro-atherogenic adhesion receptor in the inflamed vasculature.
P. Scherrer, T. Marchini, Xiao-Wei Li, Abed Al Hadi El Rabih +22 more
2025Atherosclerosis5 citations Open access
Semantic Scholar
Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling
Nikole J. Byrne, C. Koentges, E. Khan, K. Pfeil +23 more
2025Journal of Molecular and Cellular Cardiology Plus5 citations Open access
Semantic Scholar
Predictors of survival in patients with acute coronary syndrome undergoing percutaneous coronary intervention of unprotected left main coronary artery stenosis
D. Staudacher, C. Schmitt, A. Zirlik, M. Zehender +5 more
2019Catheterization and cardiovascular interventions5 citations Open access
Semantic Scholar
Coronary artery bypass grafting versus stent implantation in patients with chronic coronary syndrome and left main disease: insights from a register throughout Germany
P. Stachon, K. Kaier, Philip Hehn, A. Peikert +8 more
2021Clinical Research in Cardiology4 citations Open access
Semantic Scholar
Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation
F. Willecke, Benjamin Rupprecht, M. Gissler, K. Pfeiffer +7 more
2019Journal of Vascular Research4 citations
Semantic Scholar
CD 40 L induces inflammation and adipogenesis in adipose cells – a potential link between metabolic and cardiovascular disease
A. Missiou, D. Wolf, I. Platzer, Sandra M. Ernst +11 more
20184 citations
Semantic Scholar
Platelets, Haemostasis and Inflammation
A. Zirlik, C. Bode, M. Gawaz
2017Cardiac and Vascular Biology4 citations
Semantic Scholar
Abstract 031: A Ligand-specific Blockade of the Integrin Mac-1 Selectively Targets Pathologic Vascular Inflammation While Maintaining Protective Host-defense
D. Wolf, N. Michel, Konrad Buscher, K. Ley +4 more
20182 citations
Semantic Scholar
Cardiomyocyte‐Specific Deletion of Sirtuin 5 Accelerates the Development of Heart Failure Upon Dysregulating Purine Metabolism
Nikole J. Byrne, C. Koentges, K. Pfeil, J. Lueg +23 more
2025Acta Physiologica1 citations Open access
Semantic Scholar
Macrophage-specific IRF5 deficiency stabilizes atherosclerotic plaques in ApoE−/− mice
I. Hilgendorf, C. Haerdtner, J. Leipner, B. Dufner +5 more
20201 citations
Semantic Scholar

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