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H. Bugger · SciRah

Researcher profile · Semantic Scholar

H. Bugger

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H. Bugger — researcher profile on SciRah

h-index: 39
Works: 133
Citations: 7,681

Most-cited papers

Molecular mechanisms of diabetic cardiomyopathy
H. Bugger, E. Abel
2014Diabetologia876 citations Open access
Semantic Scholar
Mitochondrial ROS in myocardial ischemia reperfusion and remodeling.
H. Bugger, K. Pfeil
2020Biochimica et Biophysica Acta - Molecular Basis of Disease438 citations Open access
Semantic Scholar
CONTRIBUTION OF IMPAIRED MYOCARDIAL INSULIN SIGNALING TO MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS IN THE HEART
S. Boudina, H. Bugger, S. Sena, Brian T. O'Neill +16 more
2009Circulation300 citations Open access
Semantic Scholar
Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induces Post-Translational Modifications of AKAP121, DRP1 and OPA1 That Promote Mitochondrial Fission
K. Tsushima, H. Bugger, A. Wende, Jamie E. Soto +19 more
2017Circulation Research286 citations Open access
Semantic Scholar
Mitochondria in the diabetic heart.
H. Bugger, E. Abel
2010Cardiovascular Research273 citations Open access
Semantic Scholar
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology
C. Maack, M. Lehrke, J. Backs, F. Heinzel +31 more
2018European Heart Journal215 citations Open access
Semantic Scholar
Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure.
H. Bugger, M. Schwarzer, Dong Chen, A. Schrepper +7 more
2010Cardiovascular Research210 citations Open access
Semantic Scholar
SIRT3 deficiency impairs mitochondrial and contractile function in the heart
C. Koentges, K. Pfeil, T. Schnick, Sebastian Wiese +11 more
2015Basic Research in Cardiology182 citations
Semantic Scholar
Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
C. N. Koyani, I. Plastira, H. Sourij, S. Hallström +6 more
2020Pharmacological Research177 citations
Semantic Scholar
Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?
Maximilian E. Hölscher, C. Bode, H. Bugger
2016International Journal of Molecular Sciences162 citations Open access
Semantic Scholar
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Nikole J. Byrne, N. Rajasekaran, E. Abel, H. Bugger
2021Free Radical Biology & Medicine155 citations Open access
Semantic Scholar
Platelet serotonin aggravates myocardial ischemia/reperfusion injury via neutrophil degranulation
Maximilian Mauler, N. Herr, C. Schoenichen, T. Witsch +20 more
2019Circulation145 citations Open access
Semantic Scholar
Mitochondrial Mechanisms in Septic Cardiomyopathy
M. C. Cimolai, S. Alvarez, C. Bode, H. Bugger
2015International Journal of Molecular Sciences145 citations Open access
Semantic Scholar
PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy
C. Riehle, A. Wende, Vlad G. Zaha, K. Pires +12 more
2011Circulation Research132 citations Open access
Semantic Scholar
Impact of COVID-19 on Cardiovascular Disease
I. Vosko, A. Zirlik, H. Bugger
2023Viruses122 citations Open access
Semantic Scholar
Mitochondrial Mechanisms in Diabetic Cardiomyopathy
J. Gollmer, A. Zirlik, H. Bugger
2020Diabetes & Metabolism Journal114 citations Open access
Semantic Scholar
Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth
Yi Zhu, Karla M. P. Pires, K. Whitehead, Curtis D. Olsen +8 more
2013PLoS ONE113 citations Open access
Semantic Scholar
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
C. Riehle, A. Wende, S. Sena, K. Pires +15 more
2013Journal of Clinical Investigation112 citations Open access
Semantic Scholar
Latent Pulmonary Vascular Disease May Alter the Response to Therapeutic Atrial Shunt Device in Heart Failure
B. Borlaug, John E. A. Blair, M. Bergmann, H. Bugger +32 more
2022Circulation99 citations Open access
Semantic Scholar
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction
M. Wallner, D. Eaton, R. Berretta, L. Liesinger +20 more
2020Science Translational Medicine95 citations Open access
Semantic Scholar
Enhanced Cardiac Akt/Protein Kinase B Signaling Contributes to Pathological Cardiac Hypertrophy in Part by Impairing Mitochondrial Function via Transcriptional Repression of Mitochondrion-Targeted Nuclear Genes
A. Wende, Brian T. O'Neill, H. Bugger, C. Riehle +17 more
2014Molecular and Cellular Biology93 citations Open access
Semantic Scholar
Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice
Crystal L. Sloan, Joseph Tuinei, Katherine Nemetz, Jonathan E. Frandsen +6 more
2011Diabetes89 citations Open access
Semantic Scholar
Discontinuation versus continuation of renin-angiotensin-system inhibitors in COVID-19 (ACEI-COVID): a prospective, parallel group, randomised, controlled, open-label trial
A. Bauer, M. Schreinlechner, N. Sappler, T. Dolejsi +110 more
2021The Lancet Respiratory Medicine78 citations Open access
Semantic Scholar
UNCOUPLING PROTEIN DOWNREGULATION IN DOXORUBICIN INDUCED HEART FAILURE IMPROVES MITOCHONDRIAL COUPLING BUT INCREASES REACTIVE OXYGEN SPECIES GENERATION
H. Bugger, C. Guzman, C. Zechner, M. Palmeri +2 more
2010Cancer Chemotherapy and Pharmacology72 citations Open access
Semantic Scholar
Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells
Siming Liu, T. Okada, A. Assmann, Jamie E. Soto +5 more
2009PLoS ONE63 citations Open access
Semantic Scholar
Genetic Loss of Insulin Receptors Worsens Cardiac Efficiency in Diabetes
H. Bugger, C. Riehle, Bharat P. Jaishy, A. Wende +12 more
2012Journal of Molecular and Cellular Cardiology61 citations Open access
Semantic Scholar
SIRT3 in Cardiac Physiology and Disease
C. Koentges, C. Bode, H. Bugger
2016Frontiers in Cardiovascular Medicine59 citations Open access
Semantic Scholar
Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
C. Koentges, M. C. Cimolai, K. Pfeil, D. Wolf +10 more
2019Journal of Molecular and Cellular Cardiology57 citations
Semantic Scholar
Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome
J. Merz, P. Albrecht, S. von Garlen, I. Ahmed +15 more
2018Basic Research in Cardiology46 citations
Semantic Scholar
Mitochondrial sirtuins in the heart
H. Bugger, C. N. Witt, C. Bode
2016Heart Failure Reviews46 citations
Semantic Scholar
Gene Expression Analysis to Identify Mechanisms Underlying Heart Failure Susceptibility in Mice and Humans
C. Koentges, Mark E. Pepin, Carolyn Müsse, K. Pfeil +10 more
2017Basic Research in Cardiology44 citations Open access
Semantic Scholar
Preserved recovery of cardiac function following ischemia-reperfusion in mice lacking SIRT3.
C. Koentges, K. Pfeil, M. Meyer-Steenbuck, A. Lother +5 more
2016Canadian Journal of Physiology and Pharmacology44 citations
Semantic Scholar
Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility
K. Odening, I. Bódi, G. Franke, Raphaela Rieke +19 more
2018European Heart Journal41 citations
Semantic Scholar
Postpartum hormones oxytocin and prolactin cause pro-arrhythmic prolongation of cardiac repolarization in long QT syndrome type 2.
I. Bódi, John Sorge, A. Castiglione, Sylva M Glatz +10 more
2019Europace33 citations
Semantic Scholar
Myocardial mitochondrial dysfunction in mice lacking adiponectin receptor 1
C. Koentges, Alexandra König, K. Pfeil, Maximilian E. Hölscher +14 more
2015Basic Research in Cardiology33 citations
Semantic Scholar
Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome
Olesya Ilkun, N. Wilde, Joseph Tunei, K. Pires +7 more
2015Journal of Molecular and Cellular Cardiology32 citations Open access
Semantic Scholar
Mechanisms of acquired long QT syndrome in patients with propionic academia.
I. Bódi, S. Grünert, Nadine Becker, S. Stoelzle-Feix +5 more
2016Heart Rhythm31 citations
Semantic Scholar
Animal Models of Dysregulated Cardiac Metabolism
H. Bugger, Nikole J. Byrne, E. Abel
2022Circulation Research30 citations Open access
Semantic Scholar
Electro-mechanical dysfunction in long QT syndrome: Role for arrhythmogenic risk prediction and modulation by sex and sex hormones.
C. Lang, M. Menza, S. Jochem, G. Franke +9 more
2016Progress in Biophysics and Molecular Biology30 citations
Semantic Scholar
Anti-inflammatory Strategies in Atherosclerosis.
H. Bugger, A. Zirlik
2021Hämostaseologie29 citations
Semantic Scholar
NAD+ and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities
M. Abdellatif, H. Bugger, G. Kroemer, S. Sedej
2022Journal of Lipid and Atherosclerosis27 citations Open access
Semantic Scholar
Cellular Heterogeneity of the Heart
N. Anto Michel, Senka (Ljubojevic) Holzer, H. Bugger, A. Zirlik
2022Frontiers in Cardiovascular Medicine27 citations Open access
Semantic Scholar
Complications and mortality of cardiovascular emergency admissions during COVID-19 associated restrictive measures
H. Bugger, J. Gollmer, G. Pregartner, Gerit Wünsch +3 more
2020PLoS ONE27 citations Open access
Semantic Scholar
Phase-contrast magnet resonance imaging reveals regional, transmural, and base-to-apex dispersion of mechanical dysfunction in patients with long QT syndrome.
J. Brado, M. Dechant, M. Menza, Adriana Komancsek +7 more
2017Heart Rhythm26 citations
Semantic Scholar
Visualization of Sirtuin 4 Distribution between Mitochondria and the Nucleus, Based on Bimolecular Fluorescence Self-Complementation
Jeta Ramadani-Muja, B. Gottschalk, K. Pfeil, Sandra Burgstaller +6 more
2019Cells25 citations Open access
Semantic Scholar
Established and Emerging Mechanisms of Diabetic Cardiomyopathy
J. Gollmer, A. Zirlik, H. Bugger
2019Journal of Lipid and Atherosclerosis25 citations Open access
Semantic Scholar
Mitochondrial-Targeted Therapies Require Mitophagy to Prevent Oxidative Stress Induced by SOD2 Inactivation in Hypertrophied Cardiomyocytes
V. Peugnet, M. Chwastyniak, P. Mulder, S. Lancel +12 more
2022Antioxidants23 citations Open access
Semantic Scholar
Diabetes mellitus and myocardial mitochondrial dysfunction: bench to bedside.
Alexandra König, C. Bode, H. Bugger
2012Heart Failure Clinics21 citations
Semantic Scholar
Functional remodelling of perinuclear mitochondria alters nucleoplasmic Ca2+ signalling in heart failure
J. Voglhuber, M. Holzer, S. Radulović, Phung N. Thai +9 more
2022Philosophical Transactions of the Royal Society of London. Biological Sciences18 citations Open access
Semantic Scholar
Mass Spectrometry-Based Redox and Protein Profiling of Failing Human Hearts
Tamara Tomin, M. Schittmayer, S. Sedej, H. Bugger +7 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar

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