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Mark E. Pepin · SciRah

Researcher profile · Semantic Scholar

Mark E. Pepin

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Mark E. Pepin — researcher profile on SciRah

h-index: 18
Works: 43
Citations: 1,045

Most-cited papers

Resident macrophages reprogram toward a developmental state after acute kidney injury.
Jeremie M. P. Lever, T. Hull, Ravindra Boddu, Mark E. Pepin +17 more
2019JCI Insight106 citations Open access
Semantic Scholar
Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure
Mark E. Pepin, Chae-Myeong Ha, D. Crossman, S. Litovsky +7 more
2018Laboratory Investigation101 citations Open access
Semantic Scholar
Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21
Teayoun Kim, Shelly R. Nason, C. Holleman, Mark E. Pepin +12 more
2018Diabetes91 citations Open access
Semantic Scholar
DNA Methylation Reprograms Cardiac Metabolic Gene Expression in End-Stage Human Heart Failure.
Mark E. Pepin, S. Drakos, Chae-Myeong Ha, M. Tristani-Firouzi +4 more
2019American Journal of Physiology. Heart and Circulatory Physiology80 citations Open access
Semantic Scholar
Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction
Ada Admin, A. Wende, John C. Schell, Chae-Myeong Ha +15 more
2020Diabetes72 citations Open access
Semantic Scholar
The Role of Endothelial Cells in Atherosclerosis: Insights from Genetic Association Studies.
Mark E. Pepin, Rajat M. Gupta
2023American Journal of Pathology71 citations Open access
Semantic Scholar
Inhibition of Myostatin Signaling through Notch Activation following Acute Resistance Exercise
M. G. Mackenzie, D. Hamilton, Mark E. Pepin, Amy Patton +1 more
2013PLoS ONE71 citations Open access
Semantic Scholar
Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization
Manoja K. Brahma, Chae-Myeong Ha, Mark E. Pepin, S. Mia +7 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease58 citations Open access
Semantic Scholar
Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.
A. Wende, Jaetaek Kim, W. Holland, Benjamin Wayment +9 more
2017American Journal of Physiology. Heart and Circulatory Physiology57 citations Open access
Semantic Scholar
My Sweetheart Is Broken: Role of Glucose in Diabetic Cardiomyopathy
Manoja K. Brahma, Mark E. Pepin, A. Wende
2016Diabetes & Metabolism Journal49 citations Open access
Semantic Scholar
Gene Expression Analysis to Identify Mechanisms Underlying Heart Failure Susceptibility in Mice and Humans
C. Koentges, Mark E. Pepin, Carolyn Müsse, K. Pfeil +10 more
2017Basic Research in Cardiology44 citations Open access
Semantic Scholar
The human aortic endothelium undergoes dose-dependent DNA methylation in response to transient hyperglycemia.
Mark E. Pepin, C. Schiano, M. Miceli, G. Benincasa +5 more
2021Experimental Cell Research38 citations Open access
Semantic Scholar
Class-Wide Access to a Commercial Step 1 Question Bank During Preclinical Organ-Based Modules: A Pilot Project
James H. Baños, Mark E. Pepin, N. Van Wagoner
2017Academic medicine : journal of the Association of American Medical Colleges35 citations Open access
Semantic Scholar
Racial and socioeconomic disparity associates with differences in cardiac DNA methylation among men with end-stage heart failure
Mark E. Pepin, Chae-Myeong Ha, L. Potter, Sayan Bakshi +7 more
2021American Journal of Physiology. Heart and Circulatory Physiology25 citations Open access
Semantic Scholar
Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets.
Mark E. Pepin, Hayden H Bickerton, M. Bethea, Chad S. Hunter +2 more
2019Endocrinology24 citations Open access
Semantic Scholar
Identification of Nrf2-responsive microRNA networks as putative mediators of myocardial reductive stress
Justin M. Quiles, Mark E. Pepin, Sini Sunny, S. B. Shelar +6 more
2021Scientific Reports23 citations Open access
Semantic Scholar
Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance
Mark E. Pepin, Lindsey E. Padgett, R. Mcdowell, Ashley R. Burg +8 more
2018Molecular Metabolism20 citations Open access
Semantic Scholar
Differential DNA Methylation Encodes Proliferation and Senescence Programs in Human Adipose-Derived Mesenchymal Stem Cells
Mark E. Pepin, T. Infante, G. Benincasa, C. Schiano +12 more
2020Frontiers in Genetics18 citations Open access
Semantic Scholar
Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure
Christian U. Oeing, Mark E. Pepin, K. B. Saul, A. S. Agircan +10 more
2023Basic Research in Cardiology10 citations Open access
Semantic Scholar
Epigenetics in the development of diabetic cardiomyopathy
Mark E. Pepin, A. Wende
2019Epigenomics10 citations Open access
Semantic Scholar
Deep phenotyping of two pre-clinical mouse models and a cohort of RBM20 mutation carriers reveals no sex-dependent disease severity in RBM20 cardiomyopathy.
D. Lennermann, Mark E. Pepin, Markus Grosch, Laura Konrad +15 more
2022American Journal of Physiology. Heart and Circulatory Physiology9 citations Open access
Semantic Scholar
The SETD6 Methyltransferase Plays an Essential Role in Hippocampus-Dependent Memory Formation
William M. Webb, Ashleigh B. Irwin, Mark E. Pepin, Benjamin W. Henderson +6 more
2019Biological Psychiatry9 citations Open access
Semantic Scholar
Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1
Mark E. Pepin, C. Koentges, K. Pfeil, J. Gollmer +12 more
2019Frontiers in Endocrinology8 citations Open access
Semantic Scholar
Fostering a Diverse Regional Community of Physician-Scientist Trainees
Mark E. Pepin, J. Souder, A. Weaver, R. Lorenz +2 more
2022Journal of the National Medical Association6 citations Open access
Semantic Scholar
Genetic Loss of Nicotinamide Nucleotide Transhydrogenase Prevents from Cardiometabolic Heart Failure with Preserved Ejection Fraction
Mark E. Pepin, Sumra Nazir, P. Konrad, F. Schreiter +2 more
2023bioRxiv3 citations Open access
Semantic Scholar
A novel curricular framework to develop grant writing skills among MD–PhD students
J. Souder, Mark E. Pepin, Randy L. Seay, R. Lorenz +2 more
2022Journal of Clinical and Translational Science3 citations Open access
Semantic Scholar
Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets
Mark E. Pepin, A. Wende, Ronadip R. Banerjee
2018bioRxiv2 citations Open access
Semantic Scholar
A case of “smoldering” immune‐mediated thrombotic thrombocytopenic purpura manifesting as recurrent cardioembolic stroke
Mark E. Pepin, E. Saca, Soo Y. Kwon, J. May
2021Clinical Case Reports1 citations Open access
Semantic Scholar
Regulation of Myocardial Ketone Oxidative Proteins by Increased O‐GlcNAcylation
Manoja K. Brahma, M. McCrory, A. Paterson, Mark E. Pepin +2 more
2016The FASEB Journal1 citations
Semantic Scholar
CaMKII regulates cardiac metabolic substrate switching during heart failure
A. Saadatmand, Mark E. Pepin, U. Haberkorn, J. Okun +3 more
2022Journal of Molecular and Cellular Cardiology0 citations
Semantic Scholar
Abstract P3099: Identification Of Hub Genes And Construction Of Protein-protein Interaction (PPI) Network Clusters Define Racially Distinct Signatures Of Ischemic Heart Failure
Sayan Bakshi, L. Potter, Mark E. Pepin, Chae-Myeong Ha +1 more
2022Circulation Research0 citations
Semantic Scholar
Abstract 10692: Combined Methylomics and Transcriptomics Identifies a Race-Specific Signature of Ischemic Heart Failure in Atrial Natriuretic Peptide Gene Regulation
Sayan Bakshi, Mark E. Pepin, Chae-Myeong Ha, L. Potter +1 more
2021Circulation0 citations
Semantic Scholar
Abstract 11062: The δC Isoform of Ca 2+ /Calmodulin-Dependent Protein Kinase II (camk2) Regulates Cardiac Metabolic Substrate Switching in Mice
A. Saadatmand, Mark E. Pepin, M. Dewenter, U. Haberkorn +1 more
2021Circulation0 citations
Semantic Scholar
Abstract 511: Transcriptomic Analysis of End-stage Human Heart Failure Highlights Strong Interaction Effect Between Race and Diabetes
L. Potter, Mark E. Pepin, Chae-Myeong Ha, Sayan Bakshi +1 more
2020Circulation Research0 citations
Semantic Scholar
SAT-163 Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets
Mark E. Pepin, A. Wende, Ronadip R. Banerjee
2019Journal of the Endocrine Society0 citations Open access
Semantic Scholar
P3480Tissue-specific regulation of the mitochondrial proteome by adiponectin receptor 1
Johannes Gollmer, Christoph Koentges, Mark E. Pepin, K. Pfeil +4 more
2019European Heart Journal0 citations
Semantic Scholar
Abstract 945: A Novel Role of Cardiac DNA Methylation as a Regulator of Fibrosis in Human Diabetic Heart Failure
L. Potter, Mark E. Pepin, A. Wende
2019Circulation Research0 citations
Semantic Scholar
Glucagon-Receptor Signaling Regulates Mitochondrial Bioenergetics via Hepatic Farnesol X Receptor
Teayoun Kim, Shelly R. Nason, Jessica P. Antipenko, Catherina S. Vestri +8 more
2018Diabetes0 citations
Semantic Scholar
Abstract 234: Nrf2-Dependent Transcriptional and Post-Transcriptional Regulatory Responses in Reductive Stress Myocardium
Justin M. Quiles, Mark E. Pepin, S. Cinghu, A. Challa +3 more
2018Circulation Research0 citations
Semantic Scholar
Abstract 15: Glucose-Mediated Remodeling of Cardiac DNA Methylation
Mark E. Pepin, D. Crossman, Joseph P Barchue, S. Pamboukian +2 more
20170 citations
Semantic Scholar
Diabetes and Glucose Alone Regulate Cardiac ABAT Levels
Mark E. Pepin, A. Wende
2016The FASEB Journal0 citations
Semantic Scholar
Effects of Notch Signaling on Mighty Gene Expression in Skeletal Muscle: a Gene Transfection Study
Mark E. Pepin
20130 citations
Semantic Scholar
Journal Pre-proof The Role of Endothelial Cells in Atherosclerosis: Insights from Genetic Association Studies
Mark E. Pepin, Rajat M. Gupta
0 citations
Semantic Scholar

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