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N. Hoppe · SciRah

Researcher profile · Semantic Scholar

N. Hoppe

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N. Hoppe — researcher profile on SciRah

h-index: 21
Works: 61
Citations: 1,617

Most-cited papers

Atlas of the immune cell repertoire in mouse atherosclerosis defined by single-cell RNA-sequencing and mass cytometry
H. Winkels, E. Ehinger, Melanie Vassallo, Konrad Buscher +16 more
2018Circulation Research497 citations Open access
Semantic Scholar
Binding of CD40L to Mac-1’s I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis – but does not affect immunity and thrombosis in mice
D. Wolf, J. Hohmann, Ansgar Wiedemann, K. Bledzka +20 more
2011Circulation Research117 citations Open access
Semantic Scholar
P2X7 Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice
P. Stachon, A. Heidenreich, J. Merz, I. Hilgendorf +12 more
2017Circulation92 citations Open access
Semantic Scholar
Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
J. Pennig, P. Scherrer, M. Gissler, N. Anto-Michel +11 more
2019Scientific Reports70 citations Open access
Semantic Scholar
Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice
P. Stachon, Serjosha Geis, A. Peikert, A. Heidenreich +17 more
2016Arteriosclerosis, Thrombosis and Vascular Biology69 citations Open access
Semantic Scholar
P2Y6 Deficiency Limits Vascular Inflammation and Atherosclerosis in Mice
P. Stachon, A. Peikert, N. Michel, S. Hergeth +13 more
2014Arteriosclerosis, Thrombosis and Vascular Biology65 citations Open access
Semantic Scholar
The Oral Spleen Tyrosine Kinase Inhibitor Fostamatinib Attenuates Inflammation and Atherogenesis in Low-Density Lipoprotein Receptor–Deficient Mice
I. Hilgendorf, S. Eisele, I. Remer, J. Schmitz +14 more
2011Arteriosclerosis, Thrombosis and Vascular Biology63 citations Open access
Semantic Scholar
Coinhibitory Suppression of T Cell Activation by CD40 Protects Against Obesity and Adipose Tissue Inflammation in Mice
D. Wolf, Felix Jehle, N. Michel, É. N. Bukosza +27 more
2014Circulation59 citations Open access
Semantic Scholar
TRAF5 Deficiency Accelerates Atherogenesis in Mice by Increasing Inflammatory Cell Recruitment and Foam Cell Formation
A. Missiou, Philipp Rudolf, P. Stachon, D. Wolf +12 more
2010Circulation Research58 citations Open access
Semantic Scholar
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering
C. Härdtner, J. Kornemann, K. Krebs, C. Ehlert +25 more
2020Basic Research in Cardiology52 citations Open access
Semantic Scholar
Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome
J. Merz, P. Albrecht, S. von Garlen, I. Ahmed +15 more
2018Basic Research in Cardiology46 citations
Semantic Scholar
Gene Expression Analysis to Identify Mechanisms Underlying Heart Failure Susceptibility in Mice and Humans
C. Koentges, Mark E. Pepin, Carolyn Müsse, K. Pfeil +10 more
2017Basic Research in Cardiology44 citations Open access
Semantic Scholar
CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies
D. Wolf, Felix Jehle, Alexandra Ortiz Rodriguez, B. Dufner +14 more
2012PLoS ONE44 citations Open access
Semantic Scholar
Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression
A. Lindau, C. Härdtner, S. P. Hergeth, K. D. Blanz +23 more
2016Basic Research in Cardiology38 citations Open access
Semantic Scholar
Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile
J. Merz, A. Nettesheim, S. von Garlen, P. Albrecht +17 more
2021Purinergic Signalling Purinergic Signalling31 citations Open access
Semantic Scholar
Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice
J. Leipner, T. Dederichs, A. von Ehr, S. Rauterberg +14 more
2021Molecular Metabolism26 citations Open access
Semantic Scholar
Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice
F. Willecke, Shilpa Tiwari, Benjamin Rupprecht, D. Wolf +17 more
2014Thrombosis and Haemostasis24 citations Open access
Semantic Scholar
Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice
M. Gissler, P. Scherrer, N. Anto-Michel, J. Pennig +18 more
2021Thrombosis and Haemostasis23 citations Open access
Semantic Scholar
Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO)
D. Wolf, N. Bukosza, D. Engel, M. Poggi +19 more
2016Thrombosis and Haemostasis22 citations Open access
Semantic Scholar
Inflammatory Pathways Regulated by Tumor-Necrosis Receptor Associated Factor 1 Protect from Metabolic Consequences in Diet-Induced Obesity
Nathaly Anto Michel, C. Colberg, Konrad Buscher, Björn Sommer +20 more
2018Circulation Research21 citations Open access
Semantic Scholar
P2X4 deficiency reduces atherosclerosis and plaque inflammation in mice
A. Peikert, S. König, D. Suchanek, K. Rofa +19 more
2022Scientific Reports13 citations Open access
Semantic Scholar
A comparative gene expression matrix in Apoe-deficient mice identifies unique and atherosclerotic disease stage-specific gene regulation patterns in monocytes and macrophages.
C. Härdtner, Anup Kumar, C. Ehlert, T. Vico +15 more
2023Atherosclerosis10 citations Open access
Semantic Scholar
Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice
M. Gissler, N. Anto-Michel, J. Pennig, P. Scherrer +28 more
2021Arteriosclerosis, Thrombosis and Vascular Biology10 citations Open access
Semantic Scholar
Elevated platelet–leukocyte complexes are associated with, but dispensable for myocardial ischemia–reperfusion injury
C. Starz, C. Härdtner, Maximilian Mauler, B. Dufner +16 more
2022Basic Research in Cardiology9 citations Open access
Semantic Scholar
Tourmaline-quartz-cassiterite mineralization of the Land's End Granite at Nanjizal, west Cornwall
N. LeBoutillier, G. Camm, R. Shail, A. V. Bromley +2 more
20027 citations
Semantic Scholar
Endothelial CD40L serves as a pro-atherogenic adhesion receptor in the inflamed vasculature.
P. Scherrer, T. Marchini, Xiao-Wei Li, Abed Al Hadi El Rabih +22 more
2025Atherosclerosis5 citations Open access
Semantic Scholar
Abstract 19003: Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via P2Y2 in Mice
P. Stachon, Serjosha Geis, A. Heidenreich, N. Hoppe +3 more
2015Circulation5 citations
Semantic Scholar
530Extracellular ATP induces atherosclerosis and vascular inflammation via purinergic receptor 2 (P2Y2) in mice
P. Stachon, A. Peikert, A. Michel, D. Wolf +5 more
20145 citations Open access
Semantic Scholar
Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation
F. Willecke, Benjamin Rupprecht, M. Gissler, K. Pfeiffer +7 more
2019Journal of Vascular Research4 citations
Semantic Scholar
Extracellular atp contributes to atherogenesis via purinergic receptors by inducing leukocyte recruitment in mice
P. Stachon, S. Hergeth, N. Michel, B. Dufner +6 more
20134 citations Open access
Semantic Scholar
Correction: CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies
D. Wolf, Felix Jehle, Alexandra Ortiz Rodriguez, B. Dufner +14 more
2012PLoS ONE3 citations Open access
Semantic Scholar
Macrophage-specific IRF5 deficiency stabilizes atherosclerotic plaques in ApoE−/− mice
I. Hilgendorf, C. Haerdtner, J. Leipner, B. Dufner +5 more
20201 citations
Semantic Scholar
5221Knockout of purinergic receptor Y13 (P2Y13) results in an improved outcome in metabolic syndrome in mice
J. Merz, K. Rofa, D. Dimanski, I. Ahmed +4 more
2019European Heart Journal1 citations
Semantic Scholar
Cannabinoid Receptor 2 Signaling Does Not Modulate Atherogenesis in Mice
F. Willecke, Katharina Zeschky, Alexandra Ortiz Rodriguez, C. Colberg +11 more
2011PLoS ONE1 citations Open access
Semantic Scholar
Correction: P2X4 deficiency reduces atherosclerosis and plaque inflammation in mice
A. Peikert, S. König, D. Suchanek, K. Rofa +19 more
2026Scientific Reports0 citations Open access
Semantic Scholar
Knockout of purinergic receptor Y13 (P2Y13) results in an improved outcome of metabolic syndrome in mice
J. Merz, K. Rofa, L. Karnbrock, S. von Garlen +10 more
2020European Heart Journal0 citations
Semantic Scholar
Deficiency of the purinergic receptor P2X4 limits atherosclerosis in mice
S. Koenig, A. Peikert, J. Merz, K. Rofa +10 more
20200 citations
Semantic Scholar
P6291Post-myocardial infarction activation of P2X7 dependent inflammasome is crucial to develop an appropriate scar integrity
J. Merz, S. Van Garlen, I. Ahmed, D. Dimanski +5 more
2019European Heart Journal0 citations
Semantic Scholar
Platelet-leukocyte Complex Formation is Associated with, but Dispensable for Myocardial Ischemia Reperfusion Injury
C. Starz, C. Härdtner, D. Wolf, P. Stachon +13 more
2019Hämostaseologie0 citations
Semantic Scholar
P1939Tumor necrosis factor receptor-associated factor 5 (TRAF-5) deficiency exacerbates diet-induced adipose tissue inflammation and aggravates metabolic syndrome in mice
M. Gissler, N. Michel, J. Pennig, P. Scherrer +11 more
2019European Heart Journal0 citations
Semantic Scholar
P733Cholesterol uptake triggers macrophage proliferation in the plaque
I. Hilgendorf, C. Haerdtner, J. Kornemann, K. Krebs +7 more
2019European Heart Journal0 citations
Semantic Scholar
Oral Atorvastatin Induces Plaque Regression By Inhibiting Macrophage Proliferation
C. Härdtner, J. Kornemann, K. Krebs, D. Sharipova +9 more
2019Atherosclerosis0 citations
Semantic Scholar
P6346Purinergic receptor Y6 (P2Y6) deficiency impairs left ventricular function
I. Ahmed, J. Merz, D. Dimanski, K. Rofa +10 more
2019European Heart Journal0 citations
Semantic Scholar
P2843Knockout of purinergic receptor Y6 (P2Y6) leads to cardiomyopathy in mice
I. Ahmed, J. Merz, K. Rofa, B. Dufner +6 more
2018European Heart Journal0 citations
Semantic Scholar
Atherosclerosis progression and regression induced by LDLR antisense and LDLR sense oligonucleotides in mice
F. Willecke, K. Pfeiffer, N. Anto-Michel, M. Gissler +3 more
2018Atherosclerosis0 citations
Semantic Scholar
Abstract 004: Comprehensive Assessment of Immune Cells in Mouse and Human Atherosclerosis by Single-cell RNA-sequencing and Mass Cytometry
H. Winkels, E. Ehinger, M. Vassalo, Konrad Buscher +16 more
20180 citations
Semantic Scholar
Lipids trigger local macrophage proliferation in mice.
I. Hilgendorf, C. Härdtner, J. Zou, A. Jander +5 more
2017Atherosclerosis0 citations
Semantic Scholar
Abstract 19831: Lipid Im- and Export Affects Macrophage Turnover in the Plaque
I. Hilgendorf, C. Haerdtner, A. Jander, J. Zou +11 more
20170 citations
Semantic Scholar
P5584Oral atorvastatin treatment inhibits macrophage proliferation in atherosclerotic lesions
C. Haerdtner, J. Kornemann, A. Jander, J. Zou +9 more
20170 citations
Semantic Scholar
Differential effects of novel anticoagulants : FXa versus FIIa inhibition on coagulation and inflammation
P. Stachon, P. Albrecht, F. Ünal, S. von Garlen +5 more
20170 citations
Semantic Scholar

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