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R. Giadone · SciRah

Researcher profile · Semantic Scholar

R. Giadone

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R. Giadone — researcher profile on SciRah

h-index: 8
Works: 38
Citations: 313

Most-cited papers

Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
Dylan V. Neel, Himanish Basu, Georgia Gunner, Matthew Bergstresser +19 more
2022bioRxiv122 citations Open access
Semantic Scholar
Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types
Methodios Ximerakis, K. Holton, R. Giadone, Ceren Ozek +16 more
2022bioRxiv71 citations Open access
Semantic Scholar
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modeling and in vitro testing of novel therapeutics
R. Giadone, Jessica D. Rosarda, P. Akepati, A. C. Thomas +8 more
2018Amyloid: Journal of Protein Folding Disorders24 citations Open access
Semantic Scholar
Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
2020Stem Cell Reports22 citations Open access
Semantic Scholar
Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy
D. Leow, Yang-Kai Ng, Loo Chien Wang, Hiromi W L Koh +13 more
2024Journal of Clinical Investigation19 citations Open access
Semantic Scholar
Rapid Implementation of a SARS-CoV-2 Diagnostic Quantitative Real-Time PCR Test with Emergency Use Authorization at a Large Academic Safety Net Hospital
K. Vanuytsel, A. Mithal, R. Giadone, Anthony K. Yeung +7 more
2020i Medicina11 citations Open access
Semantic Scholar
Expression Levels of Lamin A or C Are Critical to Nuclear Maturation, Functional Responses, and Gene Expression Profiles in Differentiating Mouse Neutrophils
Klaudia Szymczak, M. Pelletier, Krishnakumar Malu, Anna M. Barbeau +3 more
2022ImmunoHorizons9 citations Open access
Semantic Scholar
A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring
Todd W. Dowrey, Samuel F. Cranston, Nicholas J. Skvir, Yvonne Lok +13 more
2024Aging Cell8 citations Open access
Semantic Scholar
Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets
Michelle E. Watts, R. Giadone, A. Ordureau, K. M. Holton +2 more
2024Frontiers in Cellular Neuroscience6 citations Open access
Semantic Scholar
Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures
Sabrina Ghosh, C. Villacorta-Martin, J. Lindstrom-Vautrin, D. Kenney +6 more
2023Amyloid: Journal of Protein Folding Disorders6 citations Open access
Semantic Scholar
Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition
Camille V. Edwards, Grace M. Ferri, Josue Villegas-Galaviz, Sabrina Ghosh +11 more
2024bioRxiv3 citations Open access
Semantic Scholar
A Workflow Guide to RNA-Seq Analysis of Chaperone Function and Beyond.
K. Holton, R. Giadone, Benjamin J. Lang, S. Calderwood
2023Methods in molecular biology3 citations
Semantic Scholar
Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition
Camille V. Edwards, Grace M. Ferri, Josue Villegas-Galaviz, Sabrina Ghosh +11 more
2025Amyloid: Journal of Protein Folding Disorders2 citations Open access
Semantic Scholar
qRT-PCR Platforms for Diagnosing and Reporting SARS-CoV-2 Infection in Human Samples
R. Giadone, A. Mithal, G. Miller, T. Matte +7 more
2020STAR Protocols2 citations Open access
Semantic Scholar
Rapid Implementation of a SARS-CoV-2 Diagnostic qRT-PCR Test with Emergency Use Authorization at a Large Academic Safety-Net Hospital
K. Vanuytsel, A. Mithal, R. Giadone, Anthony K. Yeung +7 more
2020Social Science Research Network2 citations Open access
Semantic Scholar
An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy
R. Giadone, K. M. Holton, Xiaoyu Hu, T. Natoli +5 more
2026Frontiers in Neuroscience1 citations Open access
Semantic Scholar
A human iPSC-derived motor neuron-myogenic cell coculture platform to evaluate neuromuscular junction innervation after axon injury and in Spinal Muscular Atrophy
Keunjung Heo, Xiangsunze Zeng, Kathleen Zhang, Kuchuan Chen +7 more
2025bioRxiv1 citations
Semantic Scholar
Patient-specific induced pluripotent stem cells for understanding and assessing novel therapeutics for multisystem transthyretin amyloid disease
R. Giadone, Sabrina Ghosh, G. Murphy
2022Novel Concepts in iPSC Disease Modeling1 citations
Semantic Scholar
DEFINING HEPATIC MODIFIERS OF ATTR AMYLOIDOSIS THROUGH THERAPEUTIC GENE EDITING IN PATIENT IPSCS
R. Giadone, Derek C. Liberti, T. Matte, Nicholas J. Skvir +7 more
20181 citations
Semantic Scholar
Disease-associated mutations directionally modulate epigenetic age in iPSC-derived tissues
Nicholas J. Skvir, Todd W. Dowrey, Samuel F. Cranston, Elise MacDonald +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
Microbiome depletion rejuvenates the aging brain
C. Gasperini, K. M. Holton, F. Limone, M. Juttu +13 more
2026bioRxiv0 citations
Semantic Scholar
Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy
Lingyu Sun, D. Leow, Loo Chien Wang, M. Eio +12 more
2026Muscle and Nerve0 citations Open access
Semantic Scholar
Emerging therapies and translational tools for drug development in systemic amyloidosis: insights from the International Society of Amyloidosis Scientific Workshop.
Gareth J. Morgan, A. Dispenzieri, Jing Fu, R. Giadone +6 more
2026Amyloid: Journal of Protein Folding Disorders0 citations
Semantic Scholar
Author Correction: Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types
Methodios Ximerakis, K. M. Holton, R. Giadone, Ceren Ozek +16 more
2025Nature Aging0 citations Open access
Semantic Scholar
An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy
R. Giadone, K. M. Holton, Xiaoyu Hu, T. Natoli +4 more
2025bioRxiv0 citations
Semantic Scholar
Additional Cover
Todd W. Dowrey, Samuel F. Cranston, Nicholas J. Skvir, Yvonne Lok +13 more
2025Aging Cell0 citations Open access
Semantic Scholar
A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring
Todd W. Dowrey, Samuel F. Cranston, Nicholas J. Skvir, Yvonne Lok +12 more
2024bioRxiv0 citations Open access
Semantic Scholar
Analyzing ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets
Michelle E. Watts, R. Giadone, A. Ordureau, K. Holton +2 more
2023bioRxiv0 citations Open access
Semantic Scholar
Abnormal Global Longitudinal Strain Correlates with Amyloidogenic Light Chain-Induced Cardiac Dysfunction via Direct Myocardial Toxicity in Patients without Significant Amyloid Fibril Deposition
Grace M. Ferri, Josue Villegas Galaviz, Tinuola B. Ajayi, R. Giadone +5 more
2023Blood0 citations Open access
Semantic Scholar
Mapping and Modelling the Molecular Mechanisms That Drive Clonal Plasma Cell-Derived Amyloidogenic Light Chain Induced Cardiotoxicity
C. Edwards, R. Giadone, Sabrina Ghosh, Gareth Morgan +2 more
2022Blood0 citations Open access
Semantic Scholar
List of contributors
C. Barragán-Álvarez, Laura Bernardini, Kristen L. Boeshore, Shana N. Busch +44 more
2022Novel Concepts in iPSC Disease Modeling0 citations
Semantic Scholar
Mapping Cellular Response to Destabilized Transthyretin Reveals Cell- and Amyloidogenic Protein-Specific Signatures
Sabrina Ghosh, C. Villacorta-Martin, J. Lindstrom-Vautrin, D. Kenney +6 more
2022bioRxiv0 citations Open access
Semantic Scholar
PROTEINS DRIVE HEPATIC PROTEOSTASIS REMODELING INDUCED PLURIPOTENT STEM CELL MODEL OF SYSTEMIC AMYLOID DISEASE 2
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
20190 citations
Semantic Scholar
Amyloidogenic Proteins Drive Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
2018bioRxiv0 citations Open access
Semantic Scholar
Studies of Murine Neutrophil and Macrophage Progenitors with Ectopic A-Type Lamins or Sun2 Expression Implicate the Importance of Nuclear Envelope Proteins in Myelopoiesis
M. Pelletier, Krishnakumar Malu, Seda C. Babroudi, R. Giadone +1 more
20140 citations
Semantic Scholar
An SCF-FBXW7 Ubiquitin Ligase Mediated Feedback Loop Facilitates GATA Factor Switching and Reinforces Commitment to Terminal Erythroid Maturation
Alireza Ghamari, Elizabeth S. Jaensch, R. Giadone, Thomas E. Akie +4 more
20140 citations
Semantic Scholar
Identifying Critical Roles for the Lamin B Receptor and Additional Nuclear Envelope Proteins in Regulating the Proliferation and Differentiation of Myeloid Progenitors
Krishnakumar Malu, Hetavi Parag Shah, M. Pelletier, R. Giadone +4 more
20130 citations
Semantic Scholar
DRIVE HEPATIC PROTEOSTASIS
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
0 citations
Semantic Scholar

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