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J. Jean · SciRah

Researcher profile · Semantic Scholar

J. Jean

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J. Jean — researcher profile on SciRah

h-index: 24
Works: 41
Citations: 3,392

Most-cited papers

Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells
Anjali Jacob, M. Morley, F. Hawkins, Katherine B. McCauley +23 more
2017Cell Stem Cell505 citations Open access
Semantic Scholar
Generation of transgene-free lung disease-specific human iPS cells using a single excisable lentiviral stem cell cassette
A. Somers, J. Jean, C. Sommer, A. Omari +14 more
2010Stem Cells448 citations Open access
Semantic Scholar
Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells
Tyler A. Longmire, L. Ikonomou, F. Hawkins, C. Christodoulou +13 more
2012Cell Stem Cell380 citations Open access
Semantic Scholar
Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
C. Terrenoire, Kai Wang, Kelvin W. Chan Tung, W. Chung +8 more
2013The Journal of General Physiology205 citations Open access
Semantic Scholar
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
F. Hawkins, Shingo Suzuki, M. Beermann, Cristina Barillà +23 more
2020bioRxiv187 citations Open access
Semantic Scholar
Regeneration of thyroid function by transplantation of differentiated pluripotent stem cells
A. Kurmann, Maria Serra, F. Hawkins, S. Rankin +13 more
2015Cell Stem Cell187 citations Open access
Semantic Scholar
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
Konstantinos-Dionysios Alysandratos, S. Russo, A. Petcherski, E. Taddeo +23 more
2020bioRxiv94 citations Open access
Semantic Scholar
Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells
A. Wilson, L. Ying, M. Liesa, Charis-Patricia Segeritz +20 more
2015Stem Cell Reports91 citations Open access
Semantic Scholar
Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines.
J. Mills, Kai Wang, Prasuna C. Paluru, L. Ying +17 more
2013Blood88 citations Open access
Semantic Scholar
Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.
A. Wilson, Letty W. Kwok, Emily Porter, Julia G. Payne +8 more
2013Molecular Therapy77 citations Open access
Semantic Scholar
Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.
J. Jean, Yue J. Liu, L. Brown, R. Marc +2 more
2002American Journal of Physiology - Lung cellular and Molecular Physiology76 citations
Semantic Scholar
Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.
J. West, Eric D. Austin, Christa F. Gaskill, S. Marriott +21 more
2014American Journal of Physiology - Cell Physiology67 citations Open access
Semantic Scholar
Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair.
Ping-Ping Kuang, R. Goldstein, Yue J. Liu, D. Rishikof +2 more
2003American Journal of Physiology - Lung cellular and Molecular Physiology55 citations
Semantic Scholar
Fibulin-5 gene expression in human lung fibroblasts is regulated by TGF-beta and phosphatidylinositol 3-kinase activity.
Ping-Ping Kuang, M. Joyce-Brady, Xiao-Hui Zhang, J. Jean +1 more
2006American Journal of Physiology - Cell Physiology52 citations
Semantic Scholar
Lung lining fluid glutathione attenuates IL-13-induced asthma.
Matthew H. Lowry, B. McAllister, J. Jean, L. Brown +8 more
2008American Journal of Respiratory Cell and Molecular Biology49 citations Open access
Semantic Scholar
Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene t1alpha.
Yu-Xia Cao, J. Jean, Mary C. Williams
2000Biochemical Journal46 citations Open access
Semantic Scholar
Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma
M. Tuzova, J. Jean, R. Hughey, L. Brown +3 more
2014Frontiers in Pharmacology41 citations Open access
Semantic Scholar
The Bax inhibitor-1 gene is differentially regulated in adult testis and developing lung by two alternative TATA-less promoters.
J. Jean, Sean M. Oakes, M. Joyce-Brady
1999Genomics41 citations Open access
Semantic Scholar
Hypoxia results in an HIF-1-dependent induction of brain-specific aldolase C in lung epithelial cells.
J. Jean, C. Rich, M. Joyce-Brady
2006American Journal of Physiology - Lung cellular and Molecular Physiology36 citations
Semantic Scholar
γ-Glutamyltransferase and Its Isoform Mediate an Endoplasmic Reticulum Stress Response*
M. Joyce-Brady, J. Jean, R. Hughey
2001Journal of Biological Chemistry31 citations Open access
Semantic Scholar
gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.
J. Jean, C. Harding, Sean M. Oakes, Qiang Yu +2 more
1999Mutagenesis31 citations
Semantic Scholar
A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells
J. Kaserman, K. Hurley, Mark Dodge, C. Villacorta-Martin +11 more
2020Stem Cell Reports26 citations Open access
Semantic Scholar
Transcription Factor Klf4, Induced in the Lung by Oxygen at Birth, Regulates Perinatal Fibroblast and Myofibroblast Differentiation
J. Jean, E. George, K. Kaestner, L. Brown +2 more
2013PLoS ONE24 citations Open access
Semantic Scholar
Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
2020Stem Cell Reports22 citations Open access
Semantic Scholar
The importance of gamma‐glutamyl transferase in lung glutathione homeostasis and antioxidant defense
J. Jean, Yue J. Liu, M. Joyce-Brady
2003Biofactors21 citations
Semantic Scholar
DANCE in developing and injured lung.
J. Jean, Ifeanyi Eruchalu, Yu-Xia Cao, M. Joyce-Brady
2002American Journal of Physiology - Lung cellular and Molecular Physiology19 citations
Semantic Scholar
Functional expression of the bradykinin-B2 receptor cDNA in Chinese hamster lung CCL39 fibroblasts.
Linda Taylor, Dennis A. Ricupero, J. Jean, B. A. Jackson +2 more
1992Biochemical and Biophysical Research Communications - BBRC17 citations Open access
Semantic Scholar
Regulation of Fgf10 gene expression in murine mesenchymal cells
J. Jean, Ji-Ning Lu, M. Joyce-Brady, W. Cardoso
2008Journal of Cellular Biochemistry14 citations
Semantic Scholar
Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.
E. Klings, Matthew H. Lowry, Gui-Hua Li, J. Jean +4 more
2009American Journal of Pathology12 citations Open access
Semantic Scholar
DEFINING HEPATIC MODIFIERS OF ATTR AMYLOIDOSIS THROUGH THERAPEUTIC GENE EDITING IN PATIENT IPSCS
R. Giadone, Derek C. Liberti, T. Matte, Nicholas J. Skvir +7 more
20181 citations
Semantic Scholar
Stem Cell Physiology and Pathophysiology Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension
J. West, E. Austin, Christa F. Gaskill, S. Marriott +21 more
20141 citations
Semantic Scholar
Pluripotent Stem Cells to Unravel the Role of Alveolar Type 2 Epithelial Cells in the Pathogenesis of Pulmonary Fibrosis
K. Alysandratos, J. Jean, Scott J. Russo, S. Mulugeta +5 more
2019B96. COMPLEX CELL BEHAVIORS IN PULMONARY FIBROSIS0 citations
Semantic Scholar
PROTEINS DRIVE HEPATIC PROTEOSTASIS REMODELING INDUCED PLURIPOTENT STEM CELL MODEL OF SYSTEMIC AMYLOID DISEASE 2
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
20190 citations
Semantic Scholar
Amyloidogenic Proteins Drive Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
2018bioRxiv0 citations Open access
Semantic Scholar
Perinatal Lung Development: The Lung at Birth
J. Jean, L. Brown, M. Joyce-Brady
20160 citations Open access
Semantic Scholar
Patient-Specific Treatment Of Long QT Syndrome Based On Pluripotent Stem Cell-Based Disease Modeling
Amulya Iyer, J. Jean, A. Omari, Kelvin W. Chan Tung +4 more
2012Asian Test Symposium0 citations
Semantic Scholar
Generation And Characterization Of An Nkx2-1-GFP Reporter Mouse
L. Ikonomou, J. Jean, Letty W. Kwok, Tyler A. Longmire +1 more
2012Asian Test Symposium0 citations
Semantic Scholar
The Generation Of Lung - Disease Specific Cystic Fibrosis IPS Cells Free Of Any Exogenous Reprogramming Transgenes
A. Somers, J. Jean, L. Oikonomou, C. Sommer +3 more
2010Asian Test Symposium0 citations
Semantic Scholar
3-kinase activity regulated by TGF-beta and phosphatidylinositol Fibulin-5 gene expression in human lung fibroblasts is
R. Goldstein, Ping-Ping Kuang, M. Joyce-Brady, Xiao-Hui Zhang +1 more
20070 citations
Semantic Scholar
DRIVE HEPATIC PROTEOSTASIS
R. Giadone, Derek C. Liberti, T. Matte, Jessica D. Rosarda +12 more
0 citations
Semantic Scholar

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