M. Voorhorst

Most-cited papers

1. Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

   C. A. Diebolder, F. Beurskens, R. D. de Jong, R. Koning +15 more

   2014Science761 citations Open access

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2. Direct in Vitro Comparison of Daratumumab with Surrogate Analogs of CD38 Antibodies MOR03087, SAR650984 and Ab79

   J. L. V. van Bueren, D. Jakobs, N. Kaldenhoven, Marcel Roza +12 more

   2014206 citations

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3. A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface

   R. D. de Jong, F. Beurskens, S. Verploegen, K. Strumane +9 more

   2016PLoS Biology204 citations Open access

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4. Antibodies to the mycobacterial 65-kd heat-shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis.

   E. D. de Graeff-Meeder, M. Voorhorst, W. van Eden, H. Schuurman +6 more

   1990American Journal of Pathology97 citations

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5. Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation

   Ewald T. J. van den Bremer, F. Beurskens, M. Voorhorst, P. Engelberts +7 more

   2015mAbs67 citations Open access

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6. Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells

   P. Engelberts, M. Voorhorst, J. Schuurman, T. van Meerten +9 more

   2016Journal of Immunology38 citations Open access

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7. Enhanced IgG Hexamerization Mediates Efficient C1q Docking and Complement-Dependent Cytotoxicity; Preclinical Proof Of Concept On Primary CLL and Burkitt Lymphoma

   R. D. de Jong, S. Verploegen, M. Voorhorst, K. Strumane +6 more

   20132 citations

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8. IgG hexamerization mediates efficient C1q docking and complement-dependent cytotoxicity (CDC)

   F. Beurskens, R. D. de Jong, M. Voorhorst, K. Strumane +6 more

   20131 citations

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9. Impact of IgG oligomerization state on the potency of complement-dependent cytotoxicity

   F. Beurskens, R. D. de Jong, Guan-Bo Wang, M. Voorhorst +5 more

   20160 citations

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10. Enhanced IgG hexamerization mediates efficient C1q docking and more rapid and substantial complement-dependent cytotoxicity; preclinical proof of concept

    F. Beurskens, C. A. Diebolder, R. D. de Jong, M. Voorhorst +10 more

    20140 citations

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11. 252Type I CD20 antibodies take over the B-cell receptor for complement-dependent cytotoxicity (CDC) of malignant B cells

    P. Engelberts, M. Voorhorst, J. Schuurman, T. van Meerten +6 more

    20120 citations

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12. Rapid Communication Antibodies to the Mycobacterial 65-kd Heat-shock Protein Are Reactive with Synovial Tissue of Adjuvant Arthritic Rats and Patients with Rheumatoid Arthritis and Osteoarthritis

    E. D. de Graeff-Meeder, M. Voorhorst, W. van Eden, H. Jin +9 more

    20070 citations

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