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E. Vanotti · SciRah

Researcher profile · Semantic Scholar

E. Vanotti

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E. Vanotti — researcher profile on SciRah

h-index: 13
Works: 49
Citations: 1,127

Most-cited papers

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
M. Menichincheri, E. Ardini, P. Magnaghi, N. Avanzi +25 more
2016Journal of Medicinal Chemistry262 citations Open access
Semantic Scholar
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
A. Montagnoli, B. Valsasina, V. Croci, M. Menichincheri +23 more
2008Nature Chemical Biology210 citations Open access
Semantic Scholar
Synthesis and immunosuppressive activity of novel prodigiosin derivatives.
R. D'Alessio, A. Bargiotti, O. Carlini, F. Colotta +9 more
2000Journal of Medicinal Chemistry146 citations
Semantic Scholar
Cdc7 kinase inhibitors: pyrrolopyridinones as potential antitumor agents. 1. Synthesis and structure-activity relationships.
E. Vanotti, R. Amici, A. Bargiotti, J. Berthelsen +20 more
2008Journal of Medicinal Chemistry86 citations Open access
Semantic Scholar
First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery.
M. Menichincheri, A. Bargiotti, J. Berthelsen, J. Bertrand +28 more
2009Journal of Medicinal Chemistry67 citations Open access
Semantic Scholar
Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding.
M. Menichincheri, C. Albanese, C. Alli, D. Ballinari +33 more
2010Journal of Medicinal Chemistry64 citations Open access
Semantic Scholar
Catecholic flavonoids acting as telomerase inhibitors.
M. Menichincheri, D. Ballinari, A. Bargiotti, L. Bonomini +9 more
2004Journal of Medicinal Chemistry59 citations Open access
Semantic Scholar
Cell division cycle 7 kinase inhibitors: 1H-pyrrolo[2,3-b]pyridines, synthesis and structure-activity relationships.
A. Ermoli, A. Bargiotti, M. Brasca, A. Ciavolella +16 more
2009Journal of Medicinal Chemistry48 citations Open access
Semantic Scholar
Synthesis of Mono- and Disubstituted 1H-Imidazo [1,2-B] Pyrazoles
P. Seneci, M. Nicola, M. Inglesi, E. Vanotti +1 more
199931 citations
Semantic Scholar
Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C-13 Using Thioesters
C. Gennari, M. Carcano, M. Donghi, N. Mongelli +2 more
199731 citations
Semantic Scholar
Anthracyclines and related substances. 2. An efficient and regiospecific synthesis of dl-7,9-dideoxydaunomycinone
K. S. Kim, E. Vanotti, A. Suarato, F. Johnson
197918 citations
Semantic Scholar
Semisynthesis of Taxol: A Highly Enantio‐ and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C13 Using Thioesters
C. Gennari, A. Vulpetti, M. Donghi, N. Mongelli +1 more
199615 citations
Semantic Scholar
REGIOSPECIFIC TOTAL SYNTHESIS OF 6-DEOXYANTHRACYCLINES: 4-DEMETHOXY-6-DEOXYDAUNORUBICIN
S. Penco, F. Angelucci, F. Arcamone, M. Ballabio +5 more
198315 citations
Semantic Scholar
Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.
S. Kimball, K. S. Kim, D. Mohanty, E. Vanotti +1 more
198213 citations
Semantic Scholar
Highly efficient synthesis of 5-benzyl-3-aminoindazoles
P. Orsini, M. Menichincheri, E. Vanotti, A. Panzeri
200910 citations
Semantic Scholar
Novel aryloxyalkylthioimidazoles as inhibitors of acyl-CoA: cholesterol-O-acyltransferase
M. Bani, R. Bormetti, W. Ceccarelli, R. Fiocchi +7 more
19957 citations
Semantic Scholar
8-Substituted purine derivatives: a new class of lipid-lowering agents
E. Vanotti, M. Bani, D. Favara, M. Gobetti +5 more
19947 citations
Semantic Scholar
Regiospecific total synthesis of 6-deoxyanthracyclines: 6-deoxycarminomycin
F. Angelucci, F. Arcamone, G. Barchielli, A. Suarato +2 more
19847 citations
Semantic Scholar
Correction to Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
M. Menichincheri, E. Ardini, P. Magnaghi, N. Avanzi +25 more
2019Journal of Medicinal Chemistry5 citations
Semantic Scholar
New rearranged products from the methylation of 13-oxobaccatin III
V. Pinciroli, W. Ceccarelli, Domeico Fusar-Bassini, M. Menichincheri +2 more
19965 citations
Semantic Scholar
Mixed 5-HT1A/D-2 Activity of a New Model of Arylpiperazines: 1-Aryl-4-( 3-(1,2-dihydronaphthalen-4-yl)-n-propyl)piperazines. Part 1. Synthesis and Structure-Activity Relationships.
R. Perrone, F. Berardi, N. Colabufo, V. Tortorella +4 more
19945 citations
Semantic Scholar
Flexible synthetic route to 6-deoxy and 11-deoxyanthracyclinones
F. Angelucci, G. Barchielli, G. Brussani, M. Gigli +5 more
19854 citations
Semantic Scholar
Regioselective halogenation of aminopyrimidinyl-pyrrole carboxylic acid derivatives
E. Vanotti, M. Caldarelli, T. Disingrini, M. Nesi +3 more
20093 citations
Semantic Scholar
ChemInform Abstract: Preparation of Novel 3,7-, 7,9- and 1,7-Disubstituted Guanines.
E. Vanotti, A. Bargiotti, R. Biancardi, V. Pinciroli +3 more
20023 citations
Semantic Scholar
Abstract DD01-01: NMS-1116354: More than an inhibitor of Cdc 7 kinase in S-phase
F. Colotta, J. Moll, B. Valsasina, E. Vanotti +16 more
20102 citations
Semantic Scholar
Erratum: First Cdc7 kinase inhibitors: Pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery (Journal of Medicinal Chemistry (2009:52(4)) (1230:1230) DOI: 10.1021/jm9000506)
K. Martina, M. Menichincheri, A. Bargiotti, J. Berthelsen +28 more
20092 citations Open access
Semantic Scholar
Cdc7 kinase inhibitors: 7-Substituted pyrrolopyridinones as potent and orally active antitumor agents
M. Menichincheri, A. Bargiotti, J. Berthelsen, R. Bossi +21 more
20072 citations
Semantic Scholar
Highly Efficient Synthesis of 5-Benzyl-3-aminoindazoles.
P. Orsini, M. Menichincheri, E. Vanotti, A. Panzeri
20091 citations
Semantic Scholar
New 13-aza baccatins
M. Menichincheri, Emanuele Arlandini, W. Ceccarelli, M. Colombo +5 more
19971 citations
Semantic Scholar
Synthesis of Novel Derivatives of 1H‐Imidazo(1,2‐b)pyrazole as Potential CNS‐Agents.
E. Vanotti, F. Fiorentini, M. Villa
19951 citations
Semantic Scholar
Crystal structure of the ALK kinase domain in complex with Cmpd 17
R. Bossi, G. Canevari, M. Fasolini, M. Menichincheri +25 more
20160 citations
Semantic Scholar
Crystal structure of the ALK kinase domain in complex with Entrectinib
R. Bossi, G. Canevari, M. Fasolini, M. Menichincheri +25 more
20160 citations
Semantic Scholar
CDC7 inhibitory crystalline salts
Massimo Zampieri, E. Vanotti, Paola Civaroli, M. G. Fornaretto
20100 citations
Semantic Scholar
368 POSTER Discovery and characterization of a new potent orally available Cdc7 inhibitor with anti-tumor activity
A. Montagnoli, E. Vanotti, Sonia Rainoldi, Vanessa Marchesi +6 more
20080 citations
Semantic Scholar
Pyrrole derivatives, thiophene and furan substituted pyridyl and pyrimidinyl, as kinase inhibitors
E. Vanotti, M. Caldarelli, A. Cirla, B. Forte +4 more
20070 citations
Semantic Scholar
398 POSTER Discovery and characterization of a small molecule inhibitor of human Cdc7 kinase
Corrado Santocanale, A. Montagnoli, P. Tenca, M. Menichincheri +6 more
20060 citations
Semantic Scholar
Pyridylpyrrol derivatives as an effective kinase inhibitors
E. Vanotti, D. AlessioRoberto, M. Tibolla, M. Varasi +4 more
20040 citations
Semantic Scholar
Pyrimidylpyrrolderivate which act as kinase inhibitors
E. Vanotti, D. AlessioRoberto, M. Tibolla, M. Varasi +4 more
20040 citations
Semantic Scholar
Halogenides 7,9-disubstituted as inhibitors guaninium tolemerasa.
A. Bargiotti, L. Bonomini, A. Ermoli, Antonella Fretta +2 more
20010 citations
Semantic Scholar
Synthesis of Mono- and Disubstituted 1H-Imidazo[1,2-b]pyrazoles.
P. Seneci, M. Nicola, M. Inglesi, E. Vanotti +1 more
19990 citations
Semantic Scholar
Prodigiosins — A New Family of Immunosuppressants Novel and Efficient Synthesis
N. Mongelli, R. D'Alessio, E. Vanotti
19990 citations
Semantic Scholar
Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C- 13 Using Thioesters.
C. Gennari, M. Carcano, M. Donghi, N. Mongelli +2 more
19970 citations
Semantic Scholar
Novel Aryloxyalkylthioimidazoles as Inhibitors of Acyl-CoA: Cholesterol-O-acyltransferase.
M. Bani, R. Bormetti, W. Ceccarelli, R. Fiocchi +7 more
19950 citations
Semantic Scholar
Inhibitors of acyl-enzyme A: cholesterol O-acyl transferase with therapeutic efficacy, their use and pharmaceutical compositions containing them
M. Palladino, E. Vanotti, M. Villa, M. Bani +2 more
19940 citations
Semantic Scholar
8-Substituted Purine Derivatives: A New Class of Lipid-Lowering Agents.
E. Vanotti, M. Bani, D. Favara, M. Gobetti +5 more
19940 citations
Semantic Scholar
Hypocholesterolemic activity of P-0654, an 8-substituted adenosine, in different experimental models
M. Bani, E. Vanotti, E. Bosisio, M. Cancellieri +2 more
19900 citations
Semantic Scholar
Flexible Synthetic Route to 6-Deoxy and 11-Deoxyanthracyclinones.
F. Angelucci, G. Barchielli, G. Brussani, M. Gigli +5 more
19860 citations
Semantic Scholar
Regiospecific Total Synthesis of ö‐Deoxyanthracyclines: 6‐Deoxycarminomycin.
F. Angelucci, F. Arcamone, G. Barachielli, A. Suarato +2 more
19840 citations
Semantic Scholar
ANTHRACYCLINES AND RELATED SUBSTANCES. 4. A NOVEL REGIO- AND STEREOSELECTIVE TOTAL SYNTHESIS OF 7-EPIDAUNOMYCINONE AND DAUNOMYCINONE
S. Kimball, K. S. Kim, D. Mohanty, E. Vanotti +1 more
19830 citations
Semantic Scholar

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