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M. Donghi · SciRah

Researcher profile · Semantic Scholar

M. Donghi

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M. Donghi — researcher profile on SciRah

h-index: 13
Works: 24
Citations: 984

Most-cited papers

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.
V. Summa, A. Petrocchi, F. Bonelli, B. Crescenzi +19 more
2008Journal of Medicinal Chemistry635 citations Open access
Semantic Scholar
Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.
Cristina Gardelli, Barbara Attenni, M. Donghi, Malte Meppen +14 more
2009Journal of Medicinal Chemistry52 citations
Semantic Scholar
A Combinatorial Approach to Polyketide-Type Libraries by Iterative Asymmetric Aldol Reactions Performed on Solid Support We thank the European Commission (TMR Network ERB-FMR XCT 96-0011 and IHP Network HPRN-CT-2000-00014), EPSRC, Pfizer, and Merck for support.
Ian Paterson, M. Donghi, Kai Gerlach
2000Angewandte Chemie51 citations
Semantic Scholar
Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors.
E. Muraglia, O. Kinzel, Cristina Gardelli, B. Crescenzi +14 more
2008Journal of Medicinal Chemistry44 citations Open access
Semantic Scholar
Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C-13 Using Thioesters
C. Gennari, M. Carcano, M. Donghi, N. Mongelli +2 more
199731 citations
Semantic Scholar
Synthesis and evaluation of novel phosphoramidate prodrugs of 2'-methyl cytidine as inhibitors of hepatitis C virus NS5B polymerase.
M. Donghi, Barbara Attenni, Cristina Gardelli, A. DiMarco +7 more
2009Bioorganic & Medicinal Chemistry Letters27 citations
Semantic Scholar
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: structure-based design and synthesis of new templates.
Savina Malancona, M. Donghi, M. Ferrara, J. I. Martín Hernando +6 more
2010Bioorganic & Medicinal Chemistry26 citations
Semantic Scholar
3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates--a new class of HIV-1 integrase inhibitors.
M. Donghi, O. Kinzel, V. Summa
2009Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
Stereocontrolled synthesis of polyketide libraries: Boron-mediated aldol reactions with aldehydes on solid support
C. Gennari, S. Ceccarelli, U. Piarulli, K. Aboutayab +2 more
199819 citations Open access
Semantic Scholar
Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition.
O. Klingler, H. Matter, M. Schudok, M. Donghi +5 more
2004Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Semisynthesis of Taxol: A Highly Enantio‐ and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C13 Using Thioesters
C. Gennari, A. Vulpetti, M. Donghi, N. Mongelli +1 more
199615 citations
Semantic Scholar
Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: discovery and optimization of a new series of P2-P4 macrocycles.
S. Harper, M. Ferrara, B. Crescenzi, Marco Pompei +11 more
2009Journal of Medicinal Chemistry13 citations
Semantic Scholar
3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates—fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors
O. Kinzel, R. Ball, M. Donghi, C. K. Maguire +4 more
200813 citations
Semantic Scholar
Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor
M. Ferrara, B. Crescenzi, M. Donghi, E. Muraglia +4 more
200712 citations
Semantic Scholar
3‐Hydroxy‐4‐oxo‐4H‐pyrido[1,2‐a]pyrimidine‐2‐carboxylates — Fast Access to a Heterocyclic Scaffold for HIV‐1 Integrase Inhibitors.
O. Kinzel, R. Ball, M. Donghi, C. K. Maguire +4 more
20092 citations
Semantic Scholar
Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part II: Sulfonamides
Simona Ponzi, C. Giuliano, M. Donghi, M. Poma +2 more
20052 citations
Semantic Scholar
Benzotriazoles in Solid‐Phase Organic Chemistry
M. Donghi, J. Habermann, S. Ley
20032 citations
Semantic Scholar
Semisynthese von Taxol: eine hochenantio- und -diastereoselektive Synthese der Seitenkette und eine neue Methode zur Esterbildung an C13 unter Verwendung von Thioestern†
Cesare Gennari, Anna Vulpetti, M. Donghi, Nicola Mongelli +1 more
19962 citations
Semantic Scholar
Regioselective Synthesis of7,8-Dihydropyrrolo[1,2-a]pyrimidin-4(6H)-ones and 7,8-Dihydropyrrolo[1,2-a]pyrimidin-2(6H)-ones
M. Donghi, S. Pesci, V. Summa, U. Koch +2 more
20101 citations
Semantic Scholar
Synthesis of a Hexahydropyrimido[1,2-a]azepine-2-carboxamide Derivative (I) Useful as an HIV Integrase Inhibitor.
M. Ferrara, B. Crescenzi, M. Donghi, E. Muraglia +4 more
20081 citations
Semantic Scholar
Patent Strategy in Pharmaceutical Industry: Are additional patents valuable?
M. Donghi
20140 citations Open access
Semantic Scholar
Regioselective Synthesis of 7,8‐Dihydropyrrolo[1,2‐a]pyrimidin‐4(6H)‐ones and 7,8‐Dihydropyrrolo[1,2‐a]pyrimidin‐2(6H)‐ones.
M. Donghi, S. Pesci, V. Summa, U. Koch +2 more
20100 citations
Semantic Scholar
Phosphoramidates d'aryle nucléosidiques destinés au traitement de l'infection virale d'arn arn dépendante
Frank Narjes, Cristina Gardelli, M. Donghi, Barbara Attenni +1 more
20070 citations
Semantic Scholar
Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C- 13 Using Thioesters.
C. Gennari, M. Carcano, M. Donghi, N. Mongelli +2 more
19970 citations
Semantic Scholar

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