Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

A. Montagnoli · SciRah

Researcher profile · Semantic Scholar

A. Montagnoli

Share profile

A. Montagnoli — researcher profile on SciRah

h-index: 23
Works: 67
Citations: 2,983

Most-cited papers

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation.
A. Montagnoli, Francesca Fiore, E. Eytan, Andrea C. Carrano +3 more
1999Genes & Development678 citations Open access
Semantic Scholar
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis
G. Rodier, A. Montagnoli, L. Di Marcotullio, P. Coulombe +3 more
2001EMBO Journal325 citations Open access
Semantic Scholar
Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma.
R. Chiarle, L. Budel, J. Skolnik, G. Frizzera +9 more
2000Blood240 citations
Semantic Scholar
Identification of Mcm2 Phosphorylation Sites by S-phase-regulating Kinases*
A. Montagnoli, B. Valsasina, D. Brotherton, S. Troiani +4 more
2006Journal of Biological Chemistry215 citations Open access
Semantic Scholar
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
A. Montagnoli, B. Valsasina, V. Croci, M. Menichincheri +23 more
2008Nature Chemical Biology210 citations Open access
Semantic Scholar
Cdc7 Inhibition Reveals a p53-Dependent Replication Checkpoint That Is Defective in Cancer Cells
A. Montagnoli, P. Tenca, F. Sola, D. Carpani +3 more
2004Cancer Research137 citations
Semantic Scholar
Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.
G. Papeo, Helena Posteri, D. Borghi, A. A. Busel +25 more
2015Journal of Medicinal Chemistry121 citations Open access
Semantic Scholar
Targeting Cell Division Cycle 7 Kinase: A New Approach for Cancer Therapy
A. Montagnoli, J. Moll, F. Colotta
2010Clinical Cancer Research114 citations Open access
Semantic Scholar
Cdc7 Is an Active Kinase in Human Cancer Cells Undergoing Replication Stress*
P. Tenca, D. Brotherton, A. Montagnoli, Sonia Rainoldi +2 more
2007Journal of Biological Chemistry92 citations Open access
Semantic Scholar
Overexpression of the nerve growth factor-inducible PC3 immediate early gene is associated with growth inhibition.
A. Montagnoli, Daniele Guardavaccaro, Giuseppe Starace, F. Tirone
1996Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research90 citations
Semantic Scholar
Cdc7 kinase inhibitors: pyrrolopyridinones as potential antitumor agents. 1. Synthesis and structure-activity relationships.
E. Vanotti, R. Amici, A. Bargiotti, J. Berthelsen +20 more
2008Journal of Medicinal Chemistry86 citations Open access
Semantic Scholar
Drf1, a novel regulatory subunit for human Cdc7 kinase
A. Montagnoli, R. Bosotti, Fabrizio Villa, M. Rialland +4 more
2002EMBO Journal84 citations Open access
Semantic Scholar
Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury
P. Magnaghi, B. Salom, L. Cozzi, N. Amboldi +14 more
2017Molecular Cancer Therapeutics67 citations
Semantic Scholar
First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery.
M. Menichincheri, A. Bargiotti, J. Berthelsen, J. Bertrand +28 more
2009Journal of Medicinal Chemistry67 citations Open access
Semantic Scholar
Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding.
M. Menichincheri, C. Albanese, C. Alli, D. Ballinari +33 more
2010Journal of Medicinal Chemistry64 citations Open access
Semantic Scholar
Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
A. Natoni, L. Murillo, Anna E. Kliszczak, M. Catherwood +4 more
2011Molecular Cancer Therapeutics49 citations Open access
Semantic Scholar
Cell division cycle 7 kinase inhibitors: 1H-pyrrolo[2,3-b]pyridines, synthesis and structure-activity relationships.
A. Ermoli, A. Bargiotti, M. Brasca, A. Ciavolella +16 more
2009Journal of Medicinal Chemistry48 citations Open access
Semantic Scholar
PARP inhibitors in cancer therapy: an update
G. Papeo, E. Casale, A. Montagnoli, A. Cirla
2013Expert Opinion on Therapeutic Patents44 citations
Semantic Scholar
Inhibition of differentiation in myoblasts deprived of the interferon-related protein PC4.
D. Guardavaccaro, Maria Teresa Ciotti, B. Schäfer, A. Montagnoli +1 more
1995Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research38 citations
Semantic Scholar
Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.
G. Papeo, P. Orsini, N. Avanzi, D. Borghi +14 more
2019ACS Medicinal Chemistry Letters36 citations Open access
Semantic Scholar
Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?
G. Papeo, B. Forte, P. Orsini, C. Perrera +3 more
2009Expert Opinion on Therapeutic Patents36 citations
Semantic Scholar
The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein
Lauren M DeSalle, E. Latres, D. Lin, E. Graner +4 more
2001Oncogene34 citations Open access
Semantic Scholar
Nerve growth factor regulates the subcellular localization of the nerve growth factor‐inducible protein PC4 in PC12 cells
D. Guardavaccaro, A. Montagnoli, Maria Teresa Ciotti, A. Gatti +4 more
1994Journal of Neuroscience Research28 citations
Semantic Scholar
Characterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular Models
A. Natoni, M. Coyne, A. Jacobsen, M. Rainey +6 more
2013Cancers22 citations Open access
Semantic Scholar
Insights into PARP Inhibitors’ Selectivity Using Fluorescence Polarization and Surface Plasmon Resonance Binding Assays
G. Papeo, N. Avanzi, S. Bettoni, A. Leone +7 more
2014Journal of biomolecular screening20 citations Open access
Semantic Scholar
Abstract 4843: NMS-P293, a PARP-1 selective inhibitor with no trapping activity and high CNS penetration, possesses potentin vivoefficacy and represents a novel therapeutic option for brain localized metastases and glioblastoma
A. Montagnoli, G. Papeo, Sonia Rainoldi, F. Caprera +5 more
2018Experimental and Molecular Therapeutics8 citations
Semantic Scholar
Abstract 1223: NMS-P293, a novel potent and selective PARP-1 inhibitor with high antitumor efficacy and tolerability
A. Montagnoli, Sonia Rainoldi, A. Ciavolella, D. Ballinari +9 more
20165 citations
Semantic Scholar
Abstract LB_A12: Initial results from 2 Phase I studies of NMS-03305293, a selective PARP1 inhibitor
M. Geurts, D. Gramatzki, S. Merler, M. Duca +18 more
2023Molecular Cancer Therapeutics4 citations
Semantic Scholar
Abstract 1638: Preclinical characterization of the novel TTK kinase inhibitor S81694 for the treatment of triple negative breast cancer
R. Colombo, M. Burbridge, Marianne Rodriguez, F. Cantero +10 more
20154 citations
Semantic Scholar
Abstract 1615: NMS-812, a novel potent PERK inhibitor that also inhibits GCN2, exhibits strong anti-tumor activity as single agent and in combination in preclinical models
Claudia Perrera, M. Pulici, P. Banfi, Nilla Avanzi +11 more
2023Cancer Research3 citations
Semantic Scholar
Abstract 2097: Targeting aneuploidy with NMS-P153, a tight binder inhibitor of the spindle assembly checkpoint MPS1 (TTK) kinase.
R. Colombo, M. Caldarelli, M. Giorgini, A. Degrassi +7 more
20133 citations
Semantic Scholar
NMS-173, a potent, covalent second generation IDH1/IDH2 inhibitor
P. Magnaghi, F. Casuscelli, E. Ardini, A. Parazzoli +16 more
2022European Journal of Cancer2 citations Open access
Semantic Scholar
Abstract DD01-01: NMS-1116354: More than an inhibitor of Cdc 7 kinase in S-phase
F. Colotta, J. Moll, B. Valsasina, E. Vanotti +16 more
20102 citations
Semantic Scholar
Erratum: First Cdc7 kinase inhibitors: Pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery (Journal of Medicinal Chemistry (2009:52(4)) (1230:1230) DOI: 10.1021/jm9000506)
K. Martina, M. Menichincheri, A. Bargiotti, J. Berthelsen +28 more
20092 citations Open access
Semantic Scholar
Cdc7 kinase inhibitors: 7-Substituted pyrrolopyridinones as potent and orally active antitumor agents
M. Menichincheri, A. Bargiotti, J. Berthelsen, R. Bossi +21 more
20072 citations
Semantic Scholar
NMS-01940153E, an MPS1 inhibitor with anti-tumor activity in relapsed or refractory unresectable Hepatocellular carcinoma
María E. Reig, S. Damian, D. Roberti, S. Maruzzelli +15 more
2022European Journal of Cancer1 citations Open access
Semantic Scholar
NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies
E. Ardini, A. Borgia, G. Texidó, R. Alzani +12 more
20161 citations
Semantic Scholar
Structure of human PARP1 catalytic domain bound to an isoindolinone inhibitor
E. Casale, M. Fasolini, G. Papeo, Helena Posteri +25 more
20151 citations
Semantic Scholar
136 Activity of the Cdc7 inhibitor NMS-1116354 as single agent and in combination in breast cancer models
A. Montagnoli, D. Ballinari, A. Ciavolella, Sonia Rainoldi +5 more
20101 citations
Semantic Scholar
Targeting Cdc7 Kinase in Multiple Myeloma.
M. Coyne, S. Naughton, P. Hayden, A. Montagnoli +2 more
20091 citations
Semantic Scholar
PHA767491, a Dual Cdc7/CDK9 Inhibitor, with Potential to Target Both Proliferation and Survival in CLL.
A. Natoni, A. Hayat, A. Montagnoli, G. Callagy +3 more
20091 citations
Semantic Scholar
Inhibition Reveals a p 53-Dependent Replication Checkpoint That Is Defective in Cancer Cells
A. Montagnoli, P. Tenca, F. Sola, D. Carpani +3 more
20041 citations
Semantic Scholar
Abstract 2933: Itareparib: A potent, selective and non-trapper PARP1 inhibitor for combination therapy with DNA damaging agents in solid tumors.
A. Galbiati, G. Papeo, N. Avanzi, F. Gasparri +8 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 4574: Highly potent inhibitors of RAD51, with first-in-class potential, targeting HR-proficient cancers
A. Galbiati, D. Asa, Pietro Picconi, Annamaria Marra +7 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 3049: Atamparib: First-in-class PARP7 inhibitor for treatment of NSCLC adenocarcinoma in monotherapy and in combination with standards of care
Genny Degani, F. Carbone, P. Banfi, L. Gianellini +10 more
2026Cancer Research0 citations
Semantic Scholar
Phase II study on safety and efficacy of NMS-01940153E, an MPS1 inhibitor with first-in-class potential, in adult patients with unresectable hepatocellular carcinoma (HCC) previously treated with systemic therapy.
L. Rimassa, M. Reig, S. Damian, D. Roberti +14 more
2023Journal of Clinical Oncology0 citations
Semantic Scholar
THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH ISOINDOLINONE INHIBITOR
E. Casale, G. Papeo, A. Montagnoli
20190 citations
Semantic Scholar
Abstract 3795: Novel and selective MELK kinase inhibitors active in breast cancer cell lines
P. Carpinelli, M. Montemartini, N. Amboldi, D. Ballinari +14 more
20160 citations
Semantic Scholar
Abstract 2851: Preclinical characterization of NMS-P648, a novel and potent PARP-1/-3 inhibitor
A. Montagnoli, G. Papeo, Sonia Rainoldi, A. Cirla +13 more
20150 citations
Semantic Scholar
Abstract 4539: NMS-P862, a novel orally available selective small molecule Cdc7 inhibitor with antitumor efficacy in breast cancer
A. Montagnoli, M. Menichincheri, N. Amboldi, D. Ballinari +9 more
20140 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

A. Isacchi×22
Invite
A. Isacchi — researcher profile on SciRah
A. Galvani×19
Invite
A. Galvani — researcher profile on SciRah
Corrado Santocanale×16
Invite
Corrado Santocanale — researcher profile on SciRah
Sonia Rainoldi×13
Invite
Sonia Rainoldi — researcher profile on SciRah

×12

Invite

G. Papeo — researcher profile on SciRah

A. Ciavolella×11

Invite

A. Ciavolella — researcher profile on SciRah

D. Ballinari×11

Invite

D. Ballinari — researcher profile on SciRah

Invite

E. Pesenti — researcher profile on SciRah

Invite

M. Ciomei — researcher profile on SciRah

B. Valsasina×10

Invite

B. Valsasina — researcher profile on SciRah

M. Menichincheri×10

Invite

M. Menichincheri — researcher profile on SciRah

Invite

A. Cirla — researcher profile on SciRah