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S. Sadekova · SciRah

Researcher profile · Semantic Scholar

S. Sadekova

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S. Sadekova — researcher profile on SciRah

h-index: 19
Works: 44
Citations: 4,302

Most-cited papers

Stromal gene expression predicts clinical outcome in breast cancer
G. Finak, N. Bertos, F. Pépin, S. Sadekova +8 more
2008Nature Medicine1,654 citations
Semantic Scholar
Multiplexed quantification of proteins and transcripts in single cells
Vanessa M. Peterson, K. Zhang, Namit Kumar, Jerelyn Wong +6 more
2017Nature Biotechnology785 citations
Semantic Scholar
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
M. Kleinschek, K. Boniface, S. Sadekova, J. Grein +9 more
2009Journal of Experimental Medicine466 citations Open access
Semantic Scholar
Human Th17 Cells Comprise Heterogeneous Subsets Including IFN-γ–Producing Cells with Distinct Properties from the Th1 Lineage
K. Boniface, W. Blumenschein, Katherine Brovont-Porth, M. McGeachy +6 more
2010Journal of Immunology209 citations Open access
Semantic Scholar
Interleukin-23-induced transcription factor Blimp-1 promotes pathogenicity of T helper 17 cells
Renu Jain, Yi Chen, Y. Kanno, B. Joyce-Shaikh +10 more
2015Immunity161 citations Open access
Semantic Scholar
Gene expression signatures of morphologically normal breast tissue identify basal-like tumors
G. Finak, S. Sadekova, F. Pépin, M. Hallett +7 more
2006Breast Cancer Research145 citations Open access
Semantic Scholar
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy
D. Zamarin, J. Ricca, S. Sadekova, A. Oseledchyk +6 more
2018Journal of Clinical Investigation128 citations Open access
Semantic Scholar
Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: a possible role in induced radioresistance.
S. Sadekova, S. Lehnert, Y.-K. T. Chow
1997International Journal of Radiation Biology93 citations
Semantic Scholar
Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23.
C. Haines, Yi Chen, W. Blumenschein, Renu Jain +11 more
2013Cell Reports84 citations Open access
Semantic Scholar
The CEACAM1-L glycoprotein associates with the actin cytoskeleton and localizes to cell-cell contact through activation of Rho-like GTPases.
S. Sadekova, Nathalie Lamarche-Vane, Xiao-Dong Li, N. Beauchemin
2000Molecular Biology of the Cell78 citations Open access
Semantic Scholar
Distinct tyrosine autophosphorylation sites mediate induction of epithelial mesenchymal like transition by an activated ErbB-2/Neu receptor
Hanane Khoury, D. Dankort, S. Sadekova, M. Naujokas +2 more
2001Oncogene69 citations Open access
Semantic Scholar
EN2 is a candidate oncogene in human breast cancer
Nicole L Martin, Marc K. Saba-El-Leil, S. Sadekova, S. Meloche +1 more
2005Oncogene65 citations Open access
Semantic Scholar
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity
B. Fournès, S. Sadekova, C. Turbide, Stephanie Letourneau +1 more
2001Oncogene49 citations
Semantic Scholar
Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells.
S. Sukumar, Douglas C. Wilson, Yingxin Yu, Jerelyn Wong +18 more
2017Cancer Research47 citations Open access
Semantic Scholar
Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells
Yun Wang, Long Cui, Peter Georgiev, L. Singh +24 more
2021Oncoimmunology41 citations Open access
Semantic Scholar
Gene-expression profiling of microdissected breast cancer microvasculature identifies distinct tumor vascular subtypes
F. Pépin, N. Bertos, Julie Laferrière, S. Sadekova +6 more
2012Breast Cancer Research31 citations Open access
Semantic Scholar
A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease.
Vivian W. Zhou, K. Agle, Xiao Chen, A. Beres +17 more
2016Journal of Clinical Investigation29 citations Open access
Semantic Scholar
TSLP is differentially regulated by vitamin D3 and cytokines in human skin
J. Landheer, B. Giovannone, S. Sadekova, S. Tjabringa +8 more
2015Immunity, Inflammation and Disease29 citations Open access
Semantic Scholar
#2202: Mucosal Autoimmunity Saturday, June 13 10:45 am–11:00 amCirculating and Gut-resident Human Th17 Cells Express CD161 and Promote Intestinal Inflammation
M. Kleinschek, K. Boniface, S. Sadekova, W. Faubion +4 more
200924 citations
Semantic Scholar
Reverse Translating Molecular Determinants of Anti–Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models
Peter Georgiev, E. Muise, Douglas E. Linn, Marlene C. Hinton +25 more
2021Molecular Cancer Therapeutics18 citations Open access
Semantic Scholar
Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab
B. Hutchins, G. Starling, M. Mccoy, D. Herzyk +23 more
2020Molecular Cancer Therapeutics18 citations
Semantic Scholar
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.
D. Zamarin, J. Ricca, S. Sadekova, A. Oseledchyk +6 more
2018Journal of Clinical Investigation17 citations Open access
Semantic Scholar
Identification of the aromatase in the breast carcinoma cell lines T47D and MCF-7.
S. Sadekova, Liat Tan, Y.-K. Chow
1994Anticancer Research16 citations
Semantic Scholar
Oncolytic virus V937 in combination with PD-1 blockade therapy to target immunologically quiescent liver and colorectal cancer
T. Tran, Jeff Grein, M. Selman, L. Annamalai +6 more
2024Molecular therapy. Oncology13 citations Open access
Semantic Scholar
Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy
L. Guelen, T. Fischmann, Jerelyn Wong, S. Mauze +32 more
2022Journal for ImmunoTherapy of Cancer13 citations Open access
Semantic Scholar
Over-expression of the NUD1-coded endo-exonuclease in Saccharomyces cerevisiae enhances DNA recombination and repair
S. Sadekova, T. Chow
1996Current Genetics12 citations
Semantic Scholar
Characterization of murine CEACAM1 in vivo reveals low expression on CD8+ T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1
R. Mcleod, M. Angagaw, T. Baral, Li-Ming Liu +12 more
2018OncoTarget7 citations Open access
Semantic Scholar
SPATA2 and CYLD inhibit T cell infiltration into colorectal cancer via regulation of IFN-γ/STAT1 axis
Tze-Guan Tan, Yulia Zybina, C. McKenna, Aleksandra Olow +5 more
2022Frontiers in Oncology2 citations Open access
Semantic Scholar
Characterization of MK-4166, a clinical agonistic mAb that targets human GITR and inhibits the generation and activity of Tregs
S. Sukumar, D. Wison, Yingxin Yu, Jerelyn Wong +13 more
20162 citations
Semantic Scholar
Histone H3 Phosphorylation in Human Skin Histoculture as a Tool to Evaluate Patient’s Response to Antiproliferative Drugs
Fernando Ugarte, Katherine Porth, S. Sadekova
2015Biomarker Insights2 citations Open access
Semantic Scholar
A colitogenic memory CD 4 + T cell population mediates gastrointestinal graft-versus-host disease
Vivian W. Zhou, K. Agle, Xiao Chen, A. Beres +17 more
20191 citations
Semantic Scholar
Abstract 562: Dinaciclib induces immunogenic cell death and enhances anti-PD-1 mediated tumor suppression
Dewan Hossain, Fernando Ugarte, A. Sawant, Mingmei Cai +4 more
20161 citations
Semantic Scholar
Development of the anti-IL-10 mAb MK-1966 in combination with in situ vaccination of a TLR9 agonist SD-101 for cancer immunotherapy
U. Phan, Roanna M. Ueda, R. Mangadu, Manjiri Sathe +11 more
20161 citations
Semantic Scholar
[The effect of hypoxia and of subsequent baro-oxygenation on the function of the microsomal oxidation system in the rat liver].
V. S. Shchugalei, A. A. Ananian, N. P. Miliutina, S. Sadekova
1992Nauchnye doklady vysshei shkoly. Biologicheskie nauki1 citations
Semantic Scholar
[Cytochrome P-450 activity and lipid peroxidation in rat liver and lung microsomes during hypoxia and followed by pressure oxygenation].
V. S. Shugaleĭ, A. A. Ananian, S. Sadekova, N. P. Miliutina
1991Voprosy medicinskoj himii1 citations
Semantic Scholar
YAP/TEAD4-regulated placental alkaline phosphatases ALPP and ALPPL2 are immunosuppressive ectonucleotidases modulated by MAPK inhibitors
J. Martin, Bruce Huang, T. Ehrenberger, A. R. Hasan +18 more
2025bioRxiv0 citations Open access
Semantic Scholar
Immunotherapy Response in Mouse Syngeneic Tumor Models
Peter Georgiev, E. Muise, Douglas E. Linn, Marlene C. Hinton +27 more
20210 citations
Semantic Scholar
Amendment history : Corrigendum ( October 2018 ) PD-L 1 in tumor microenvironment mediates resistance to oncolytic immunotherapy
D. Zamarin, J. Ricca, S. Sadekova, A. Oseledchyk +6 more
20180 citations
Semantic Scholar
Association d'un antagoniste du pd-1 et d'un oligonucléotide cpg du type c pour le traitement du cancer
Yu Ying, A. Denker, S. Sadekova, U. Phan +5 more
20160 citations
Semantic Scholar
Combination of antagonist pd-1 and oligonucleotide type cpg-c for cancer treatment
Ин Юй, Эндрю Эван Денкер, S. Sadekova, Юэн Труонг Пхан +5 more
20160 citations
Semantic Scholar
Combinaison d'un anticorps anti-il-10 et d'un oligonucléotide de type cpg-c pour le traitement du cancer
Yu Ying, E. Chartash, S. Sadekova, U. Phan +4 more
20160 citations
Semantic Scholar
Coordinate Expression of Beta 2 Integrins and the Interleukin 23 Receptor Define a Pathogenic CD4+ T Cell Population That Induces Colonic Inflammation during Graft Versus Host Disease
K. Agle, Vivian W. Zhou, Xiao Chen, A. Beres +11 more
20140 citations Open access
Semantic Scholar
The regulation of thymic stromal lymphopoietin in skin by vitamin D3 is distinct between mouse and human
J. Landheer, B. Giovannone, G. Tjabringa, C. Hofstra +6 more
20110 citations
Semantic Scholar
185 Genetic analysis of radioresistance in a human ovarian tumor cell line
S. Lehnert, S. Sadekova, M. Park, T. Hudson +1 more
20060 citations
Semantic Scholar

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