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Gerald J. Fetterly · SciRah

Researcher profile · Semantic Scholar

Gerald J. Fetterly

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Gerald J. Fetterly — researcher profile on SciRah

h-index: 26
Works: 125
Citations: 2,274

Most-cited papers

Sorafenib: a clinical and pharmacologic review
R. Iyer, Gerald J. Fetterly, A. Lugade, Y. Thanavala
2010Expert Opinion on Pharmacotherapy163 citations
Semantic Scholar
Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study
R. Ramanathan, R. Korn, N. Raghunand, J. Sachdev +11 more
2017Clinical Cancer Research148 citations Open access
Semantic Scholar
Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361).
M. Smolinski, Yahao Bu, James L. Clements, I. Gelman +8 more
2018Journal of Medicinal Chemistry83 citations Open access
Semantic Scholar
A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer
E. Antonarakis, E. Heath, E. Posadas, Evan Y. Yu +9 more
2013Cancer Chemotherapy and Pharmacology66 citations Open access
Semantic Scholar
Sunitinib dose-escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modifications
Remi Adelaiye, E. Ciamporcero, K. M. Miles, P. Sotomayor +13 more
2014Molecular Cancer Therapeutics65 citations Open access
Semantic Scholar
A Phase I/II Study of Erlotinib in Combination with the Anti-Insulin-Like Growth Factor-1 Receptor Monoclonal Antibody IMC-A12 (Cixutumumab) in Patients with Advanced Non-small Cell Lung Cancer
Andrew Weickhardt, R. Doebele, A. Oton, Janice Lettieri +15 more
2012Journal of Thoracic Oncology57 citations Open access
Semantic Scholar
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas
Elizabeth A. Brem, K. Thudium, Sapna Khubchandani, P. Tsai +14 more
2011British Journal of Haematology52 citations Open access
Semantic Scholar
Influence of Sex and Race on Mycophenolic Acid Pharmacokinetics in Stable African American and Caucasian Renal Transplant Recipients
K. Tornatore, C. Meaney, G. Wilding, Shirley Chang +8 more
2015Clinical Pharmacokinetics44 citations Open access
Semantic Scholar
A phase I study of the histone deacetylase (HDAC) inhibitor entinostat, in combination with sorafenib in patients with advanced solid tumors
N. Ngamphaiboon, G. Dy, Wen W. Ma, Yujie Zhao +6 more
2014Investigational new drugs43 citations
Semantic Scholar
A Phase I, Pharmacokinetic, and Pharmacodynamic Study of Two Schedules of Vorinostat in Combination with 5-Fluorouracil and Leucovorin in Patients with Refractory Solid Tumors
M. Fakih, Gerald J. Fetterly, M. Egorin, J. Muindi +6 more
2010Clinical Cancer Research42 citations Open access
Semantic Scholar
Dose-Dependent Sorafenib-Induced Immunosuppression Is Associated with Aberrant NFAT Activation and Expression of PD-1 in T Cells
R. Iyer, O. Maguire, Minhyung Kim, L. Curtin +6 more
2019Cancers38 citations Open access
Semantic Scholar
A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies
A. Naing, R. Cohen, G. Dy, David S. Hong +6 more
2013Investigational new drugs38 citations
Semantic Scholar
Physiologically based pharmacokinetic models for everolimus and sorafenib in mice
Dipti K. Pawaskar, R. Straubinger, Gerald J. Fetterly, Bonnie H. Hylander +3 more
2013Cancer Chemotherapy and Pharmacology36 citations Open access
Semantic Scholar
Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data
Gerald J. Fetterly, Urvi Aras, Patricia D. Meholick, C. Takimoto +8 more
2013Journal of clinical pharmacology36 citations
Semantic Scholar
Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens
W. Kim, Li Zhang, J. Wilton, Gerald J. Fetterly +11 more
2014Clinical Cancer Research33 citations Open access
Semantic Scholar
Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice
Dipti K. Pawaskar, R. Straubinger, Gerald J. Fetterly, Bonnie H. Hylander +3 more
2013Cancer Chemotherapy and Pharmacology30 citations Open access
Semantic Scholar
Methyl Selenocysteine: single-dose pharmacokinetics in men
J. Marshall, C. Ip, K. Romano, Gerald J. Fetterly +9 more
2011Cancer Prevention Research29 citations Open access
Semantic Scholar
A Pilot Study Comparing the Effect of Flaxseed, Aromatase Inhibitor, and the Combination on Breast Tumor Biomarkers
S. McCann, S. Edge, D. Hicks, L. Thompson +6 more
2014Nutrition and Cancer28 citations Open access
Semantic Scholar
Efficacy and safety of topical brepocitinib cream for mild-to-moderate chronic plaque psoriasis: a phase IIb, randomised, double-blind, vehicle-controlled, parallel-group study.
M. Landis, Stacy Smith, G. Berstein, Gerald J. Fetterly +9 more
2023British Journal of Dermatology26 citations Open access
Semantic Scholar
Tumor Priming by Apo2L/TRAIL Reduces Interstitial Fluid Pressure and Enhances Efficacy of Liposomal Gemcitabine in a Patient Derived Xenograft Tumor Model
B. Hylander, Arindam Sen, S. Beachy, R. Pitoniak +6 more
2015Journal of Controlled Release25 citations Open access
Semantic Scholar
A phase Ib study of the FGFR/VEGFR inhibitor dovitinib with gemcitabine and capecitabine in advanced solid tumor and pancreatic cancer patients
Wen W. Ma, Hao Xie, Gerald J. Fetterly, L. Pitzonka +12 more
2019American Journal of Clinical Oncology24 citations Open access
Semantic Scholar
Aflibercept Exerts Antivascular Effects and Enhances Levels of Anthracycline Chemotherapy In vivo in Human Acute Myeloid Leukemia Models
D. Lal, Jennifer A. Park, K. Demock, Joseph Marinaro +9 more
2010Molecular Cancer Therapeutics23 citations Open access
Semantic Scholar
Androgenic Biomarker Profiling in Human Matrices and Cell Culture Samples Using High Through put, Electrospray Tandem Mass Spectrometry
J. Wilton, Mark Titus, E. Efstathiou, Gerald J. Fetterly +1 more
2014The Prostate21 citations Open access
Semantic Scholar
Abstract LB-406: Phase 1 study of the Smac mimetic TL32711 in adult subjects with advanced solid tumors and lymphoma to evaluate safety, pharmacokinetics, pharmacodynamics, and antitumor activity
R. Amaravadi, R. Schilder, G. Dy, Wen W. Ma +8 more
201120 citations
Semantic Scholar
Development and verification of a pharmacokinetic model to optimize physiologic replacement of rhIGF-1/rhIGFBP-3 in preterm infants
Jou-Ku Chung, B. Hallberg, I. Hansen-Pupp, M. Graham +7 more
2017Pediatric Research19 citations Open access
Semantic Scholar
Abstract CT224: Pilot study in patients with advanced solid tumors to evaluate feasibility of ferumoxytol (FMX) as tumor imaging agent prior to MM-398, a nanoliposomal irinotecan (nal-IRI)
R. Ramanathan, R. Korn, J. Sachdev, Gerald J. Fetterly +9 more
201419 citations
Semantic Scholar
Efficacy, Safety, and Potential Biomarkers of Sunitinib and Transarterial Chemoembolization (TACE) Combination in Advanced Hepatocellular Carcinoma (HCC): Phase II Trial
V. Pokuri, G. Tomaszewski, S. Ait-Oudhia, A. Groman +7 more
2016American Journal of Clinical Oncology18 citations
Semantic Scholar
Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants
R. Tummala, P. Diegelman, S. Hector, D. Kramer +5 more
2010Cancer Chemotherapy and Pharmacology18 citations Open access
Semantic Scholar
Safety and efficacy of MET inhibitor tivantinib (ARQ 197) combined with sorafenib in patients (pts) with hepatocellular carcinoma (HCC) from a phase I study.
I. Puzanov, J. Sosman, A. Santoro, R. Martell +14 more
201217 citations
Semantic Scholar
Phase 1b study of the oral gemcitabine ‘Pro-drug’ LY2334737 in combination with capecitabine in patients with advanced solid tumors
J. Infante, K. Benhadji, G. Dy, Gerald J. Fetterly +4 more
2015Investigational new drugs16 citations
Semantic Scholar
Interactions of Everolimus and Sorafenib in Pancreatic Cancer Cells
Dipti K. Pawaskar, R. Straubinger, Gerald J. Fetterly, Wen W. Ma +1 more
2012AAPS Journal16 citations Open access
Semantic Scholar
Efficacy and Safety of PF-07038124 in Patients With Atopic Dermatitis and Plaque Psoriasis
L. Eichenfield, S. Tarabar, S. Forman, Alfonso García-Bello +6 more
2023JAMA dermatology15 citations Open access
Semantic Scholar
A phase I study of the toll-like receptor 5 (TLR5) agonist, entolimod in patients (pts) with advanced cancers.
Hatoon Bakhribah, G. Dy, Wen W. Ma, Yujie Zhao +16 more
201515 citations
Semantic Scholar
Development of a Preclinical PK/PD Model to Assess Antitumor Response of a Sequential Aflibercept and Doxorubicin-Dosing Strategy in Acute Myeloid Leukemia
Gerald J. Fetterly, Urvi Aras, D. Lal, M. Murphy +2 more
2013AAPS Journal14 citations Open access
Semantic Scholar
Safety and efficacy of MET inhibitor tivantinib (ARQ 197) combined with sorafenib in patients (pts) with NRAS wild-type or mutant melanoma from a phase I study.
J. Means-Powell, A. Adjei, I. Puzanov, G. Dy +8 more
201213 citations
Semantic Scholar
Carboplatin Pharmacokinetics in a Patient Receiving Hemodialysis
M. Fong, Gerald J. Fetterly, Lori J. McDougald, R. Iyer
2013Pharmacotherapy12 citations Open access
Semantic Scholar
Bridging Sunitinib Exposure to Time‐to‐Tumor Progression in Hepatocellular Carcinoma Patients With Mathematical Modeling of an Angiogenic Biomarker
S. Ait-Oudhia, D. Mager, V. Pokuri, G. Tomaszewski +4 more
2016CPT: Pharmacometrics & Systems Pharmacology11 citations Open access
Semantic Scholar
Clinical pharmacokinetics of the Smac-mimetic birinapant (TL32711) as a single agent and in combination with multiple chemotherapy regimens.
Gerald J. Fetterly, Biao Liu, N. Senzer, R. Amaravadi +9 more
20128 citations
Semantic Scholar
Efficacy in selected tumor types in a phase I study of the c-MET inhibitor ARQ 197 in combination with sorafenib.
A. Adjei, J. Sosman, R. Martell, G. Dy +13 more
2011Journal of Clinical Oncology8 citations
Semantic Scholar
261 Lesion characterization with ferumoxytol MRI in patients with advanced solid tumors and correlation with treatment response to MM-398, nanoliposomal irinotecan (nal-IRI)
R. Ramanathan, R. Korn, J. Sachdev, Gerald J. Fetterly +9 more
20147 citations
Semantic Scholar
A phase Ib dose escalation study of oral monotherapy with KX2-391 in elderly patients with acute myeloid leukemia
M. Kasner, Molly Halloran, Jonathan Pan, E. Ritchie +4 more
2022Investigational new drugs6 citations Open access
Semantic Scholar
Phase 1 study of the angiopoietin 1/2 neutralizing peptibody, trebananib, in acute myeloid leukemia.
Eunice S. Wang, Gerald J. Fetterly, L. Pitzonka, W. Brady +9 more
20146 citations
Semantic Scholar
Clinical and Biologic Effects Of The Angiopoietin 1/2 Neutralizing Peptibody, Trebananib (AMG 386), In Acute Myeloid Leukemia Patients
Gerald J. Fetterly, W. Brady, W. Tan, J. Greene +7 more
20136 citations
Semantic Scholar
Pharmacokinetic analysis of the FAK scaffold inhibitor C4 in dogs
J. Wilton, E. Kurenova, L. Pitzonka, A. Gaudy +4 more
2014European journal of drug metabolism and pharmacokinetics5 citations Open access
Semantic Scholar
Abstract 1939: TL32711, a novel Smac mimetic, exerts significant antitumor efficacy in primary pancreatic adenocarcinoma model
Wen W. Ma, Hao Zhang, B. Hylander, C. LeVea +8 more
20125 citations
Semantic Scholar
A phase I dose-escalation trial evaluating ARQ 197 administered in combination with sorafenib in adult patients (pts) with advanced solid tumors.
A. Adjei, J. Sosman, G. Dy, Wen W. Ma +6 more
20105 citations
Semantic Scholar
A phase 1 open label, dose escalation study of intravenous paricalcitol in combination with gemcitabine in patients with advanced malignancies
C. Fountzilas, M. Javle, W. Tan, Yi-gong Ma +3 more
2018Cancer4 citations Open access
Semantic Scholar
Abstract 3912: MM-310, a novel EphA2-targeted docetaxel nanoliposome
D. Kirpotin, Suresh K. Tipparaju, Z. Huang, W. Kamoun +12 more
20164 citations
Semantic Scholar
A pharmacokinetic and dose-escalating study of paclitaxel injection concentrate for nano-dispersion (PICN) alone and with carboplatin in patients with advanced solid tumors.
Wen W. Ma, E. Lam, G. Dy, J. Diamond +12 more
20134 citations
Semantic Scholar
Synergism between clofarabine and decitabine through p53R2: A pharmacodynamic drug-drug interaction modeling
K. Thudium, Sampa Ghoshal, Gerald J. Fetterly, Jason P. Den Haese +2 more
2012Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis4 citations Open access
Semantic Scholar

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