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J. Muindi · SciRah

Researcher profile · Semantic Scholar

J. Muindi

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J. Muindi — researcher profile on SciRah

h-index: 30
Works: 59
Citations: 2,610

Most-cited papers

Anti-tumor activity of calcitriol: pre-clinical and clinical studies.
D. Trump, P. Hershberger, Ronald J. Bernardi, Sharmilla Ahmed +4 more
2004Journal of Steroid Biochemistry and Molecular Biology190 citations
Semantic Scholar
A Phase I trial of calcitriol (1,25-dihydroxycholecalciferol) in patients with advanced malignancy.
David A. Smith, Candace S. Johnson, Catherine Freeman, J. Muindi +2 more
1999Clinical Cancer Research190 citations
Semantic Scholar
Feasibility of retinoids for the treatment of emphysema study.
M. Roth, J. Connett, J. D'Armiento, R. Foronjy +15 more
2006Chest163 citations
Semantic Scholar
Hydroxyl radical production and DNA damage induced by anthracycline‐iron complex
J. Muindi, B. K. Sinha, L. Gianni, Charles E. Myers
1984FEBS Letters146 citations Open access
Semantic Scholar
Pharmacokinetics of high‐dose oral calcitriol: Results from a phase 1 trial of calcitriol and paclitaxel
J. Muindi, Yibing Peng, D. Potter, P. Hershberger +5 more
2002Clinical pharmacology and therapy132 citations
Semantic Scholar
Phase II trial of high‐dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) and dexamethasone in androgen‐independent prostate cancer
D. Trump, D. Potter, J. Muindi, A. Brufsky +1 more
2006Cancer111 citations Open access
Semantic Scholar
Chemotherapy is linked to severe vitamin D deficiency in patients with colorectal cancer
M. Fakih, D. Trump, Candace S. Johnson, L. Tian +2 more
2008International Journal of Colorectal Disease101 citations Open access
Semantic Scholar
Epigenetic Regulation of Vitamin D 24-Hydroxylase/CYP24A1 in Human Prostate Cancer
W. Luo, A. Karpf, Kristin K. Deeb, J. Muindi +3 more
2010Cancer Research98 citations Open access
Semantic Scholar
A Phase I Pharmacokinetic and Pharmacodynamic Study of Intravenous Calcitriol in Combination with Oral Gefitinib in Patients with Advanced Solid Tumors
M. Fakih, D. Trump, J. Muindi, J. Black +7 more
2007Clinical Cancer Research96 citations Open access
Semantic Scholar
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
J. Muindi, Wei-dong Yu, Ying-Yu Ma, Kristie L. Engler +3 more
2010Endocrinology93 citations Open access
Semantic Scholar
Epigenetic Silencing of CYP24 in Tumor-derived Endothelial Cells Contributes to Selective Growth Inhibition by Calcitriol*
Ivy Chung, A. Karpf, J. Muindi, J. Conroy +3 more
2007Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Novel retinoic acid receptor-alpha transcripts in acute promyelocytic leukemia responsive to all-trans-retinoic acid.
W. Miller, R. Warrell, S. Frankel, A. Jakubowski +3 more
1990Journal of the National Cancer Institute77 citations
Semantic Scholar
Vitamin D compounds: clinical development as cancer therapy and prevention agents.
D. Trump, J. Muindi, M. Fakih, Wei-dong Yu +1 more
2006Anticancer Research76 citations
Semantic Scholar
Clinical pharmacology of all-trans retinoic acid.
J. Muindi, C. Young, R. Warrell
1994Leukemia70 citations
Semantic Scholar
Pharmacokinetics of 1α,25-Dihydroxyvitamin D3 in Normal Mice after Systemic Exposure to Effective and Safe Antitumor Doses
J. Muindi, R. Modzelewski, Yibing Peng, D. Trump +1 more
2004Oncology67 citations
Semantic Scholar
Calcitriol enhances gemcitabine antitumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system
Wei-dong Yu, Ying-Yu Ma, Geraldine Flynn, J. Muindi +3 more
2010Cell Cycle66 citations Open access
Semantic Scholar
Low 25(OH) Vitamin D3 Levels Are Associated with Adverse Outcome in Newly-Diagnosed Intensively-Treated Adult Acute Myeloid Leukemia Patients
Hun-Ju Lee, J. Muindi, W. Tan, Qiang Hu +14 more
2013Cancer65 citations Open access
Semantic Scholar
Differences in O2 reduction by the iron complexes of adriamycin and daunomycin: the importance of the sidechain hydroxyl group.
Jay L. Zweier, L. Gianni, J. Muindi, Charles E. Myers
1986Biochimica et Biophysica Acta63 citations
Semantic Scholar
Effect of 25-Hydroxyvitamin D Status on Serological Response to Influenza Vaccine in Prostate Cancer Patients
M. Chadha, M. Fakih, J. Muindi, L. Tian +3 more
2010The Prostate56 citations Open access
Semantic Scholar
Role of iron in adriamycin biochemistry.
Charles E. Myers, L. Gianni, Jay L. Zweier, J. Muindi +2 more
1986Federation proceedings54 citations
Semantic Scholar
Thiol-dependent DNA damage produced by anthracycline-iron complexes. The structure-activity relationships and molecular mechanisms.
J. Muindi, B. K. Sinha, L. Gianni, C. Myers
1985Molecular Pharmacology54 citations
Semantic Scholar
A randomized phase II study of two doses of vorinostat in combination with 5-FU/LV in patients with refractory colorectal cancer
M. Fakih, A. Groman, J. McMahon, G. Wilding +1 more
2012Cancer Chemotherapy and Pharmacology49 citations
Semantic Scholar
The antitumor efficacy of calcitriol: preclinical studies.
Candace S. Johnson, J. Muindi, P. Hershberger, D. Trump
2006Anticancer Research49 citations
Semantic Scholar
A phase I and pharmacokinetics study of intravenous calcitriol in combination with oral dexamethasone and gefitinib in patients with advanced solid tumors
J. Muindi, Candace S. Johnson, D. Trump, Renee Christy +2 more
2009Cancer Chemotherapy and Pharmacology48 citations Open access
Semantic Scholar
A Phase I, Pharmacokinetic, and Pharmacodynamic Study of Two Schedules of Vorinostat in Combination with 5-Fluorouracil and Leucovorin in Patients with Refractory Solid Tumors
M. Fakih, Gerald J. Fetterly, M. Egorin, J. Muindi +6 more
2010Clinical Cancer Research42 citations Open access
Semantic Scholar
In vitro and in vivo evaluation of combined calcitriol and cisplatin in dogs with spontaneously occurring tumors
K. Rassnick, J. Muindi, Candace S. Johnson, C. Balkman +5 more
2008Cancer Chemotherapy and Pharmacology42 citations Open access
Semantic Scholar
Serum Vitamin D Metabolites in Colorectal Cancer Patients Receiving Cholecalciferol Supplementation: Correlation with Polymorphisms in the Vitamin D Genes
J. Muindi, A. Adjei, Zengrui Wu, Isabel Olson +8 more
2013Hormones & cancer38 citations Open access
Semantic Scholar
5-Iminodaunomycin. An anthracycline with unique properties.
Charles E. Myers, J. Muindi, Jay L. Zweier, B. K. Sinha
1987Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Modulation of all-trans retinoic acid pharmacokinetics by liarozole
V. Miller, J. Rigas, J. Muindi, W. Tong +3 more
2004Cancer Chemotherapy and Pharmacology36 citations
Semantic Scholar
CYP24 splicing variants are associated with different patterns of constitutive and calcitriol-inducible CYP24 activity in human prostate cancer cell lines.
J. Muindi, A. Nganga, Kristie L. Engler, L. Coignet +2 more
2007Journal of Steroid Biochemistry and Molecular Biology33 citations
Semantic Scholar
Pharmacokinetics of liquid calcitriol formulation in advanced solid tumor patients: comparison with caplet formulation
J. Muindi, D. Potter, Yibing Peng, Candace S. Johnson +1 more
2005Cancer Chemotherapy and Pharmacology28 citations
Semantic Scholar
A phase I/II pharmacokinetic and pharmacogenomic study of calcitriol in combination with cisplatin and docetaxel in advanced non-small-cell lung cancer
N. Ramnath, S. Daignault-Newton, G. Dy, J. Muindi +9 more
2013Cancer Chemotherapy and Pharmacology27 citations Open access
Semantic Scholar
Comparison of quantiles for several normal populations
Xin-Min Li, Lili Tian, Juan Wang, J. Muindi
2012Computational Statistics & Data Analysis22 citations
Semantic Scholar
Pentamethylmelamine (PMM): Phase I clinical and pharmacokinetic studies.
J. Muindi, D. R. Newell, I. Smith, K. Harrap
1983British Journal of Cancer21 citations Open access
Semantic Scholar
Pharmacokinetics and Metabolism of All‐trans‐and 13‐cis‐Retinoic Acid in Pulmonary Emphysema Patients
J. Muindi, Michael D. Roth, R. Wise, J. Connett +6 more
2008Journal of clinical pharmacology20 citations
Semantic Scholar
Long-term stability of a patient-convenient 1 mg/ml suspension of tacrolimus for accurate maintenance of stable therapeutic levels
A. Elefante, J. Muindi, Kathleen West, Lauren M. Dunford +7 more
2006Bone Marrow Transplantation17 citations
Semantic Scholar
A prospective clinical trial of cholecalciferol 2000 IU/day in colorectal cancer patients: evidence of a chemotherapy-response interaction.
M. Fakih, C. Andrews, J. McMahon, J. Muindi
2012Anticancer Research13 citations
Semantic Scholar
Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients
J. Muindi, Yibing Peng, John W. Wilson, Candace S. Johnson +2 more
2006Cancer Chemotherapy and Pharmacology10 citations
Semantic Scholar
Abstract 82: A comprehensive characterization of cholecalciferol supplementation induced changes in the vitamin D3metabolic pathway in metastatic colorectal cancer patients
J. Muindi, A. Adjei, Zengrui Wu, L. Tian +4 more
20107 citations
Semantic Scholar
Oral bioavailability of DN101, a concentrated formulation of calcitriol, in tumor-bearing dogs
K. Rassnick, J. Muindi, Candace S. Johnson, D. Bailey +1 more
2010Cancer Chemotherapy and Pharmacology6 citations Open access
Semantic Scholar
A Limited Sampling Method for the Estimation of Serum Calcitriol Area under the Curve in Cancer Patients
J. Muindi, John W. Wilson, Ying Peng, Mary Jo Capozolli +2 more
2003Journal of clinical pharmacology6 citations
Semantic Scholar
Vitamin D and Colorectal Cancer
M. Fakih, Annette Y. Sunga, J. Muindi
20114 citations
Semantic Scholar
Subnormal Vitamin D Levels Are Associated with Adverse Outcome In Newly-Diagnosed Similarly-Treated Adult Acute Myeloid Leukemia (AML) Patients.
Hun Lee, J. Muindi, Tan Wei, G. Wilding +11 more
20104 citations
Semantic Scholar
Some observations on congestive cardiac failure in African patients in Dar es Salaam.
W. Makene, J. Muindi
1976East African Medical Journal4 citations
Semantic Scholar
Enhanced gemcitabine (G) exposure in combination with escalating doses of paricalcitol [19-nor-1 alpha, 25-(OH)2 D2] (P) in patients with advanced malignancies.
R. Iyer, Gerald J. Fetterly, M. Javle, W. Tan +6 more
20101 citations
Semantic Scholar
A phase I and pharmacokinetic (PK) study of intravenous (IV) calcitriol and gefitinib assessing EGFR pharmacodynamic (PD) interactions through serial skin biopsies
M. Fakih, Candace S. Johnson, J. Muindi, J. Black +5 more
20051 citations
Semantic Scholar
Serum and Bile 25(OH)D3 and 1,25(OH)2D3 Levels in Patients with Cancers Affecting the Gall Bladder and Biliary Duct: 232
Jeena Yoo, Isabel Olson, J. Muindi, R. Iyer +3 more
20120 citations
Semantic Scholar
A phase I/II clinical trial of intravenous (I.V.) calcitriol with fixed doses of cisplatin and docetaxel in advanced non-small cell lung cancer.
N. Ramnath, S. Daignault-Newton, G. Dy, J. Muindi +7 more
20120 citations
Semantic Scholar
Serum 25(OH) vitamin D3 response to vitamin D3 supplementation in men with prostate cancer: Results of a randomized phase II trial.
M. al-Hussaini, Candace S. Johnson, J. Muindi, M. Chadha +9 more
2011Journal of Clinical Oncology0 citations
Semantic Scholar
6104 POSTER A Phase II Randomized Study of Two Doses of Vorinostat in Combination With 5-FU/LV in Patients With Refractory Colorectal Cancer (CRC)
M. Fakih, A. Groman, J. McMahon, K. Romano +4 more
20110 citations
Semantic Scholar

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Candace S. Johnson×30
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M. Fakih×11
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Wei-dong Yu×5
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