Researcher profile · Semantic Scholar

Yahao Bu

h-index: 11
Works: 26
Citations: 581

Most-cited papers

Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361).
M. Smolinski, Yahao Bu, James L. Clements, I. Gelman +8 more
2018Journal of Medicinal Chemistry83 citations Open access
Semantic Scholar
SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway*
B. Su, Yahao Bu, D. Engelberg, I. Gelman
2009Journal of Biological Chemistry83 citations Open access
Semantic Scholar
SSeCKS metastasis-suppressing activity in MatLyLu prostate cancer cells correlates with vascular endothelial growth factor inhibition.
B. Su, Qiao Zheng, M. Vaughan, Yahao Bu +1 more
2006Cancer Research72 citations Open access
Semantic Scholar
Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities.
Asal Fallah-Tafti, A. Foroumadi, R. Tiwari, A. Shirazi +5 more
2011European journal of medicinal chemistry67 citations Open access
Semantic Scholar
Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion
S. Sachdev, Yahao Bu, I. Gelman
2009BMC Cancer64 citations Open access
Semantic Scholar
Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations.
S. Urgaonkar, K. Nosol, A. Said, Nader N. Nasief +4 more
2021Journal of Medicinal Chemistry60 citations Open access
Semantic Scholar
Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts
M. Anbalagan, Alaa M Ali, Ryan K. Jones, C. Marsden +5 more
2012Molecular Cancer Therapeutics42 citations Open access
Semantic Scholar
v-Src-mediated Down-regulation of SSeCKS Metastasis Suppressor Gene Promoter by the Recruitment of HDAC1 into a USF1-Sp1-Sp3 Complex*
Yahao Bu, I. Gelman
2007Journal of Biological Chemistry35 citations Open access
Semantic Scholar
An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model
Cheng-Jian Tu, Jun Li, Yahao Bu, D. Hangauer +1 more
2012Journal of Proteomics28 citations Open access
Semantic Scholar
Role for Transcription Factor TFII-I in the Suppression Of SSeCKS/Gravin/Akap12 Transcription by Src
Yahao Bu, Ling-Qiu Gao, Irwin H. Gelman
2011International Journal of Cancer19 citations Open access
Semantic Scholar
KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
M. Ciesielski, Yahao Bu, S. Munich, Paola Teegarden +5 more
2018Journal of Neuro-Oncology13 citations
Semantic Scholar
Ion Current-Based Proteomic Profiling for Understanding the Inhibitory Effect of Tumor Necrosis Factor Alpha on Myogenic Differentiation.
Cheng-Jian Tu, Yahao Bu, M. Vujčić, S. Shen +5 more
2016Journal of Proteome Research5 citations Open access
Semantic Scholar
Parameter inversion of the concrete hydration heat source based on physics-informed neural network
Yahao Bu, Bing-Han Xue, Zhen-Hua Huang, Musong Yang +2 more
2026International Journal of Heat and Mass Transfer4 citations
Semantic Scholar
Growth Factor Inhibition Prostate Cancer Cells Correlates with Vascular Endothelial SSeCKS Metastasis-Suppressing Activity in MatLyLu
B. Su, Qiao Zheng, M. Vaughan, Yahao Bu +1 more
20064 citations
Semantic Scholar
Abstract 2487: Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials
Yahao Bu, M. Smolinski, J. Qu, L. Kazim +3 more
20102 citations
Semantic Scholar
[Role of P13K/Akt pathway in chronic myeloid leukemia].
L. He, Jing Tang, Yahao Bu
2013Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi1 citations
Semantic Scholar
Preclinical Development Peptidomimetic Src / Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth , Metastasis in Human ER / PR / HER 2-Negative Tumor Xenografts
M. Anbalagan, Alaa M Ali, Ryan K. Jones, C. Marsden +5 more
20121 citations
Semantic Scholar
Highly efficient thermal analysis of zoned RCC gravity dams based on a multi-region tagged PIELM (MRT-PIELM)
Bing-Han Xue, Zhen-Hua Huang, Yahao Bu, Man-Jun Li +2 more
2026International Journal of Heat and Mass Transfer0 citations
Semantic Scholar
Flow field fitting analysis of earth-rock dam leakage based on an image-based hybrid Quadtree-SBFEM
Bing-Han Xue, Yahao Bu, Shuai-Hao Su, Si-Ye Zhang +3 more
2026Journal of Applied Geophysics0 citations
Semantic Scholar
Abstract 4717: Effective preclinical management of angiosarcoma with oral paclitaxel
M. Cutler, Krista E. Belko, Yahao Bu, Alissa R. Verone-Boyle +5 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Clinical study on treatment of adult T lymphoblastic lymphoma with Hyper-CVAD regime
L. He, L. Meng, Jing Tang, Yahao Bu +1 more
20120 citations
Semantic Scholar
Erratum
Yahao Bu, Ling-Qiu Gao, A. Kazim, Kyoung‐Soo Choi
20110 citations Open access
Semantic Scholar
Abstract 2534: Suppression of prostate cancer growth by the Src signaling inhibitor, KXO1 (KX2-391)
Yahao Bu, Ling-Qiu Gao, D. Hangauer, I. Gelman
20100 citations
Semantic Scholar
A role for the general transcriptional factor II -I (TFII-I) in Src-mediated transcriptional suppression of SSeCKS/Gravin/AKAP12
Yahao Bu, I. Gelman
20080 citations
Semantic Scholar
Dissection of the SSeCKS metastasis suppressor gene promoters: Identification of v -Src responsive elements
Yahao Bu
20070 citations
Semantic Scholar
Simulation and inversion of temperature fields in concrete gravity dams based on region-indicating material discontinuity capturing physics-informed neural network
Zhen-Hua Huang, Bing-Han Xue, Yahao Bu, Man-Jun Li +1 more
International journal of thermal sciences0 citations
Semantic Scholar

James L. Clements

×3

J. Lau×3

B. Su×3

J. Qu×3

Ling-Qiu Gao×3

Zhen-Hua Huang×3

D. Cutler×2

R. Kwan×2