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F. Larbret · SciRah

Researcher profile · Semantic Scholar

F. Larbret

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F. Larbret — researcher profile on SciRah

h-index: 21
Works: 41
Citations: 2,568

Most-cited papers

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.
I. Ben-Sahra, K. Laurent, Sandy Giuliano, F. Larbret +10 more
2010Cancer Research524 citations Open access
Semantic Scholar
The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera.
S. Dupont, A. Massé, C. James, I. Teyssandier +9 more
2007Blood208 citations
Semantic Scholar
Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling.
L. Lordier, Abdelali Jalil, F. Aurade, F. Larbret +4 more
2008Blood199 citations Open access
Semantic Scholar
Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera.
V. Ugo, C. Marzac, I. Teyssandier, F. Larbret +4 more
2004Experimental Hematology189 citations Open access
Semantic Scholar
Proplatelet formation is regulated by the Rho/ROCK pathway.
Yun-Hua Chang, F. Aurade, F. Larbret, Yanyan Zhang +8 more
2005Blood181 citations
Semantic Scholar
FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia.
H. Raslova, E. Komura, J. Le Couédic, F. Larbret +6 more
2004Journal of Clinical Investigation167 citations Open access
Semantic Scholar
A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis.
Olena Klimchenko, M. Mori, A. Distefano, T. Langlois +6 more
2009Blood160 citations
Semantic Scholar
Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens.
M. Martínez, F. Larbret, F. Zobairi, J. Coulombe +4 more
2006Blood144 citations Open access
Semantic Scholar
Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach.
H. Raslova, A. Kauffmann, Dalila Sekkaï, H. Ripoche +8 more
2007Blood114 citations
Semantic Scholar
Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis.
R. Chaligné, C. James, C. Tonetti, R. Besancenot +9 more
2007Blood108 citations
Semantic Scholar
Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors.
S. Giraudier, H. Chagraoui, E. Komura, S. Barnache +11 more
2002Blood81 citations
Semantic Scholar
Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression.
E. Komura, H. Chagraoui, Véronique Mansat de Mas, B. Blanchet +7 more
2003Experimental Hematology60 citations Open access
Semantic Scholar
P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1.
Laure Gilles, R. Guièze, D. Bluteau, Véronique Cordette-Lagarde +6 more
2008Blood56 citations Open access
Semantic Scholar
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix‐mediated tumor cell adaptation and tolerance to BRAF‐targeted therapy in melanoma
I. Berestjuk, M. Lecacheur, Alexandrine Carminati, S. Diazzi +13 more
2021EMBO Molecular Medicine54 citations Open access
Semantic Scholar
A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma
C. Girard, M. Lecacheur, Rania Ben Jouira, I. Berestjuk +14 more
2020Cancer Research53 citations Open access
Semantic Scholar
CXCR7 receptors facilitate the progression of colon carcinoma within lung not within liver
E. Guillemot, B. Karimdjee-Soilihi, E. Pradelli, M. Benchetrit +8 more
2012British Journal of Cancer48 citations Open access
Semantic Scholar
Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process.
L. Lordier, Yun-Hua Chang, Abdelali Jalil, F. Aurade +8 more
2010Blood47 citations
Semantic Scholar
Inhibition of the GTPase Rac1 Mediates the Antimigratory Effects of Metformin in Prostate Cancer Cells
B. Dirat, I. Ader, M. Golzio, Fabienne Massa +9 more
2014Molecular Cancer Therapeutics43 citations Open access
Semantic Scholar
Nanoblades allow high-level genome editing in murine and human organoids
V. Tiroille, Adrien Krug, E. Bokobza, Michel Kahi +18 more
2023Molecular Therapy: Nucleic Acids24 citations Open access
Semantic Scholar
Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma
S. Diazzi, A. Baeri, J. Fassy, M. Lecacheur +18 more
2022EMBO Molecular Medicine24 citations Open access
Semantic Scholar
A role for Peroxisome Proliferator-Activated Receptor Beta in T cell development
I. Mothe‐Satney, J. Murdaca, B. Sibille, A. Rousseau +8 more
2016Scientific Reports24 citations Open access
Semantic Scholar
SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis
C. Luci, Élodie Vieira, Manon Bourinet, D. Rousseau +11 more
2021Cellular and Molecular Gastroenterology and Hepatology11 citations Open access
Semantic Scholar
Saccharomyces boulardii Strain CNCM I-745 Modifies the Mononuclear Phagocytes Response in the Small Intestine of Mice Following Salmonella Typhimurium Infection
Lidia Ibáñez, Rodolphe Pontier-Bres, F. Larbret, A. Rekima +3 more
2019Frontiers in Immunology10 citations Open access
Semantic Scholar
Thrombopoietin responsiveness reflects the number of doublings undergone by megakaryocyte progenitors.
J. Paulus, N. Debili, F. Larbret, J. Levin +1 more
2004Blood10 citations
Semantic Scholar
CD99 isoforms regulate CD1a expression in human monocyte‐derived DCs through ATF‐2/CREB‐1 phosphorylation
Karim Mahiddine, Aude Mallavialle, H. Bziouech, F. Larbret +2 more
2016European Journal of Immunology9 citations Open access
Semantic Scholar
Technical Advance: Actin CytoFRET, a novel FRET flow cytometry method for detection of actin dynamics in resting and activated T cell
F. Larbret, Nicholas Dubois, F. Brau, E. Guillemot +4 more
2013Journal of Leukocyte Biology7 citations
Semantic Scholar
Metformin targets the GTPase Rac1 to inhibit prostate cancer cell migration
B. Dirat, I. Ader, M. Golzio, A. Mettouchi +7 more
2014Cancer & Metabolism5 citations Open access
Semantic Scholar
Deubiquitinase Inhibitors Impair Leukemic Cell Migration Through Cofilin Oxidation and Alteration of Actin Reorganization
F. Larbret, Pierric Biber, Nicholas Dubois, Stoyan Ivanov +3 more
2022Frontiers in Pharmacology3 citations Open access
Semantic Scholar
Apoptosis in Prostate Cancer Cells Metformin and 2-Deoxyglucose Induces p 53-Dependent Targeting Cancer Cell Metabolism : The Combination of
I. Ben-Sahra, K. Laurent, Sandy Giuliano, F. Larbret +10 more
20103 citations
Semantic Scholar
Targeting DDR1 and DDR2 overcomes matrix-mediated melanoma cell adaptation to BRAF-targeted therapy
I. Berestjuk, M. Lecacheur, S. Diazzi, Christopher Rovera +10 more
2019bioRxiv2 citations Open access
Semantic Scholar
Blockade of pro-fibrotic response mediated by the miR-143/-145 cluster prevents targeted therapy-induced phenotypic plasticity and resistance in melanoma
S. Diazzi, A. Baeri, J. Fassy, M. Lecacheur +16 more
2021bioRxiv1 citations Open access
Semantic Scholar
Myeloid cells glutaminolysis controls monocyte numbers and macrophage efferocytosis during atherosclerosis
Johanna Merlin, Stoyan Ivanov, A. Sergushichev, Marion I. Stunault +6 more
2018Atherosclerosis1 citations
Semantic Scholar
Metformin targets the GTPase Rac1 to inhibit prostate cancer cell migration
B. Dirat, I. Ader, M. Golzio, A. Mettouchi +7 more
2014Cancer & Metabolism1 citations Open access
Semantic Scholar
Nanoblades allow high-level genome editing in organoids
Victor Tirolle, Adrien Krug, E. Bokobza, M. Bulcaen +13 more
2022bioRxiv0 citations Open access
Semantic Scholar
undergone by megakaryocyte progenitors Thrombopoietin responsiveness reflects the number of doublings
J. Paulus, N. Debili, F. Larbret, J. Levin +1 more
20130 citations
Semantic Scholar
primitive myelofibrosis Evidence for MPL W515L/K mutations in hematopoietic stem cells in
S. Giraudier, F. Mazurier, I. Godin, K. Maloum +5 more
20130 citations
Semantic Scholar
CD99 differentially modulate transcriptional regulation of classical MHC class I and CD1a molecules (130.23)
Karim Mahiddine, G. Bernard, F. Larbret, Aude Mallavialle +2 more
2010Journal of Immunology0 citations
Semantic Scholar
William defects in the contractile ring and Rho / Rock signaling Megakaryocyte endomitosis is a failure of late cytokinesis related to
L. Lordier, Abdelali Jalil, F. Aurade, F. Larbret +4 more
20080 citations
Semantic Scholar
MAP Kinase Signaling Pathway Induced by TPO Is a Negative Regulator of Proplatelet Formation in Human Megakaryocytes.
S. de Botton, F. Aurade, Yun-Hua Chang, Rivat Christine +6 more
20060 citations
Semantic Scholar
Thrombopoietin dose-response curves reflect the number of doublings undergone by human megakaryocyte progenitors
J. Paulus, N. Debili, F. Larbret, J. Levin +1 more
20040 citations
Semantic Scholar
Thrombopoietin (TPO) responsiveness reflects the number of doublings (NbD) undergone by human megakaryocyte (MK) progenitors
J. Paulus, N. Debili, F. Larbret, J. Levin +1 more
20030 citations
Semantic Scholar

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