Researcher profile · Semantic Scholar

D. Bluteau

h-index: 18
Works: 27
Citations: 1,554

Most-cited papers

Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation.
D. Bluteau, A. Balduini, Nathalie Balayn, M. Currao +10 more
2014Journal of Clinical Investigation176 citations Open access
Semantic Scholar
RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization
L. Lordier, D. Bluteau, Abdelali Jalil, C. Legrand +11 more
2012Nature Communications154 citations Open access
Semantic Scholar
From hematopoietic stem cells to platelets
Yun-Hua Chang, D. Bluteau, N. Debili, W. Vainchenker
2007Journal of Thrombosis and Haemostasis141 citations Open access
Semantic Scholar
Regulation of megakaryocyte maturation and platelet formation
D. Bluteau, L. Lordier, A. D. Di Stefano, Y. Chang +3 more
2009Journal of Thrombosis and Haemostasis124 citations Open access
Semantic Scholar
Biallelic inactivation of REV7 is associated with Fanconi anemia.
D. Bluteau, Julien Masliah-Planchon, Connor S. Clairmont, Alix Rousseau +12 more
2016Journal of Clinical Investigation120 citations Open access
Semantic Scholar
Dysmegakaryopoiesis of FPD/AML pedigrees with constitutional RUNX1 mutations is linked to myosin II deregulated expression.
D. Bluteau, A. C. Glembotsky, A. Raimbault, Nathalie Balayn +9 more
2012Blood103 citations Open access
Semantic Scholar
Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia.
I. Antony-Debré, V. Manchev, Nathalie Balayn, D. Bluteau +16 more
2015Blood94 citations Open access
Semantic Scholar
Biallelic truncating FANCM mutations cause early-onset cancer but not Fanconi anemia
M. Bogliolo, D. Bluteau, J. Lespinasse, R. Pujol +6 more
2017Genetics in Medicine80 citations Open access
Semantic Scholar
MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.
I. Antony-Debré, D. Bluteau, R. Itzykson, V. Baccini +11 more
2012Blood80 citations Open access
Semantic Scholar
MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9.
Laure Gilles, D. Bluteau, S. Boukour, Yun-Hua Chang +7 more
2009Blood79 citations Open access
Semantic Scholar
Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia.
M. Sébert, S. Gachet, T. Leblanc, Alix Rousseau +62 more
2023Cell Stem Cell62 citations Open access
Semantic Scholar
LymphocytesInduce CD103 Expression in Human CD8 T Smad and NFAT Pathways Cooperate To
M. Mokrani, Jihène Klibi, D. Bluteau, G. Bismuth +1 more
201461 citations
Semantic Scholar
Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia.
D. Bluteau, Laure Gilles, Morgane Hilpert, I. Antony-Debré +13 more
2011Blood58 citations Open access
Semantic Scholar
P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1.
Laure Gilles, R. Guièze, D. Bluteau, Véronique Cordette-Lagarde +6 more
2008Blood56 citations Open access
Semantic Scholar
Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets
A. C. Glembotsky, D. Bluteau, Y. R. Espasandin, N. P. Goette +8 more
2014Journal of Thrombosis and Haemostasis53 citations Open access
Semantic Scholar
OTT-MAL Is a Deregulated Activator of Serum Response Factor-Dependent Gene Expression
A. Descot, M. Rex-Haffner, G. Courtois, D. Bluteau +5 more
2008Molecular and Cellular Biology42 citations Open access
Semantic Scholar
p19INK4d Controls Hematopoietic Stem Cells in a Cell-Autonomous Manner during Genotoxic Stress and through the Microenvironment during Aging
Morgane Hilpert, C. Legrand, D. Bluteau, Nathalie Balayn +10 more
2014Stem Cell Reports32 citations Open access
Semantic Scholar
Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia
A. C. Glembotsky, Dominika Sliwa, D. Bluteau, Nathalie Balayn +11 more
2018Haematologica22 citations Open access
Semantic Scholar
Biallelic inactivation of REV7 is associated with Fanconi anemia.
D. Bluteau, Julien Masliah-Planchon, Connor S. Clairmont, Alix Rousseau +12 more
2017Journal of Clinical Investigation8 citations Open access
Semantic Scholar
Activity of OTX015 (MK-8628), a BET-Bromodomain Inhibitor, in Acute Myeloid Leukemia (AML) Progenitor Cells
Louise Roulin, Ashfaq Ali, A. Massé, M. Coudé +12 more
20153 citations
Semantic Scholar
Phase I/II study of the PARP inhibitor olaparib and irinotecan in children and young adults with recurrent/refractory malignancies: Arm D of the AcSé-ESMART trial.
S. Gatz, P. Berlanga, G. Le Teuff, Ivan Valiev +35 more
2026Clinical Cancer Research2 citations Open access
Semantic Scholar
MDM4 overexpression alleviates developmental and hematopoietic defects in Fancg deficient mice
Maeva Loock, Carèle Fédronie, Carine Torset, L. Hernandez +12 more
2025Leukemia2 citations Open access
Semantic Scholar
Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients
M. Sébert, S. Gachet, T. Leblanc, Alix Rousseau +17 more
2021Blood1 citations Open access
Semantic Scholar
Amendment history : Corrigendum ( March 2017 ) Biallelic inactivation of REV 7 is associated with Fanconi anemia
D. Bluteau, Julien Masliah-Planchon, Connor S. Clairmont, Alix Rousseau +12 more
20191 citations
Semantic Scholar
ZMAT3 alleviates cell death in Fanconi anemia via adaptation of sphingolipid metabolism
Maeva Loock, Blandine Lucchini, E. Latour, Margot Tissandier +10 more
2026Science Advances0 citations Open access
Semantic Scholar
From normal hematopoiesis to malignancies: Highlights from the 2021 Meeting of the Club Hematopoiesis and Oncogenesis.
M. Troadec, F. Porteu, M. Arcangeli, A. Foudi +7 more
2023Bulletin du Cancer0 citations Open access
Semantic Scholar
RUNX1-Induced Silencing of Non-Muscle Myosin Iib (MYH10) Is Required for Megakaryocyte Polyploidization
D. Bluteau, L. Lordier, I. Antony-Debré, Abdelali Jalil +11 more
20110 citations
Semantic Scholar

R. Favier

×7

J. Soulier×7

T. Leblanc×6

Nathalie Balayn×5

Yun-Hua Chang×5

Alix Rousseau×5

S. Gachet×5

G. Socié×5