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W. Vainchenker · SciRah

Researcher profile · Semantic Scholar

W. Vainchenker

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W. Vainchenker — researcher profile on SciRah

h-index: 109
Works: 698
Citations: 42K

Most-cited papers

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
Ya-Hsuan Ho, R. del Toro, José Rivera-Torres, Justyna Rak +16 more
2019Cell Stem Cell282 citations Open access
Semantic Scholar
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
A. Rodriguez-Meira, Ruggiero Norfo, S. Wen, Agathe L. Chédeville +30 more
2023Nature Genetics143 citations Open access
Semantic Scholar
Immunosuppression by Mutated Calreticulin Released from Malignant Cells.
Peng Liu, Li-Wei Zhao, Friedemann Loos, C. Marty +14 more
2019Molecules and Cells106 citations Open access
Semantic Scholar
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome.
C. Bellanné-Chantelot, B. Schmaltz-Panneau, C. Marty, O. Fenneteau +34 more
2018Blood106 citations Open access
Semantic Scholar
Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.
C. Pecquet, I. Chachoua, Anita Roy, Thomas Balligand +17 more
2019Blood94 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
W. Vainchenker
2019Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature76 citations
Semantic Scholar
Biological drivers of clinical phenotype in myelofibrosis
J. Mascarenhas, Hélène F. E. Gleitz, H. Chifotides, C. Harrison +8 more
2022Leukemia55 citations Open access
Semantic Scholar
Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases
E. Josefsson, W. Vainchenker, C. James
2020International Journal of Molecular Sciences55 citations Open access
Semantic Scholar
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene-driven myeloid leukemia.
Cécile K. Lopez, Esteve Noguera, V. Stavropoulou, E. Robert +32 more
2019Cancer Discovery49 citations Open access
Semantic Scholar
Inferring the dynamic of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms.
M. Mosca, Gurvan Hermange, A. Tisserand, Robert Noble +24 more
2021Blood43 citations Open access
Semantic Scholar
Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development
Thomas Balligand, Y. Achouri, C. Pecquet, G. Gaudray +10 more
2019Leukemia43 citations Open access
Semantic Scholar
Megakaryocyte polyploidization: role in platelet production
W. Vainchenker, H. Raslova
2020Platelets41 citations
Semantic Scholar
Functional Consequences of Mutations in Myeloproliferative Neoplasms
S. Constantinescu, W. Vainchenker, G. Levy, Nicolas Papadopoulos
2021HemaSphere40 citations Open access
Semantic Scholar
Calreticulin del52 and ins5 knock-in mice recapitulate different myeloproliferative phenotypes observed in patients with MPN
Camélia Benlabiod, Maira da Costa Cacemiro, A. Nédélec, V. Edmond +10 more
2020Nature Communications39 citations Open access
Semantic Scholar
Interferon-Alpha (IFN) Therapy Discontinuation Is Feasible in Myeloproliferative Neoplasm (MPN) Patients with Complete Hematological Remission
Rafael Daltro de Oliveira, J. Soret-Dulphy, Lin-Pierre Zhao, C. Marcault +10 more
202037 citations Open access
Semantic Scholar
Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms
C. Pecquet, Nicolas Papadopoulos, Thomas Balligand, I. Chachoua +38 more
2022Blood34 citations Open access
Semantic Scholar
Impact of NFE2 mutations on AML transformation and overall survival in patients with myeloproliferative neoplasms (MPN).
C. Marcault, Lin-Pierre Zhao, Nabih Maslah, E. Verger +15 more
2021Blood34 citations Open access
Semantic Scholar
JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML
Tracy Dagher, Nabih Maslah, V. Edmond, B. Cassinat +10 more
2020Journal of Experimental Medicine32 citations Open access
Semantic Scholar
MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors.
M. Lutzmann, F. Bernex, de Jesus Cindy da Costa, Dana Hodroj +10 more
2019Cell Reports32 citations Open access
Semantic Scholar
Germline genetic factors in the pathogenesis of myeloproliferative neoplasms.
C. Bellanné-Chantelot, Graciela Rabadán Moraes, B. Schmaltz-Panneau, C. Marty +2 more
2020Blood reviews30 citations Open access
Semantic Scholar
Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity.
A. Donada, Nathalie Balayn, Dominika Sliwa, L. Lordier +13 more
2019Blood30 citations Open access
Semantic Scholar
Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)
Edimara Reis, Rebecca A Buonpane, H. Çelik, C. Marty +12 more
2022Blood27 citations Open access
Semantic Scholar
The role of the thrombopoietin receptor MPL in myeloproliferative neoplasms: recent findings and potential therapeutic applications
W. Vainchenker, I. Plo, C. Marty, Leila Varghese +1 more
2019Expert Review of Hematology27 citations Open access
Semantic Scholar
Inferring the initiation and development of myeloproliferative neoplasms
Gurvan Hermange, Alicia Rakotonirainy, Mahmoud Bentriou, A. Tisserand +6 more
2022Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Macrophage migration inhibitory factor is overproduced through EGR1 in TET2low resting monocytes
E. Pronier, Aygun Imanci, D. Selimoglu-Buet, Bouchra Badaoui +16 more
2022Communications Biology22 citations Open access
Semantic Scholar
Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model
B. Arkoun, E. Robert, Fabien Boudia, Stefania Mazzi +23 more
2022Journal of Clinical Investigation22 citations Open access
Semantic Scholar
A p53-JAK-STAT connection involved in myeloproliferative neoplasm pathogenesis and progression to secondary acute myeloid leukemia.
H. Goyal, I. Chachoua, C. Pecquet, W. Vainchenker +1 more
2020Blood reviews22 citations Open access
Semantic Scholar
Germline ATG2B/GSKIP-containing 14q32 duplication predisposes to early clonal hematopoiesis leading to myeloid neoplasms
Jean Pegliasco, P. Hirsch, C. Marzac, F. Isnard +27 more
2021Leukemia20 citations
Semantic Scholar
Role of Rho-GTPases in megakaryopoiesis
W. Vainchenker, B. Arkoun, F. Basso-Valentina, L. Lordier +2 more
2021Small GTPases19 citations Open access
Semantic Scholar
Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms
Mira El-Khoury, Xénia Cabagnols, M. Mosca, Gaëlle Vertenoeil +20 more
2020Oncogene19 citations Open access
Semantic Scholar
Description of a Knock-In Mouse Model of JAK2V617F MPN Emerging from a Minority of Mutated Hematopoietic Stem Cells.
Olivier Mansier, B. Kilani, Amélie V. Guitart, Alexandre Guy +6 more
2019Blood19 citations Open access
Semantic Scholar
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice
C. Willekens, L. Laplane, Tracy Dagher, Camélia Benlabiod +22 more
2023Leukemia17 citations Open access
Semantic Scholar
The Pediatric Acute Leukemia Fusion Oncogene ETO2-GLIS2 Increases Self-Renewal and Alters Differentiation in a Human Induced Pluripotent Stem Cells-Derived Model
S. Bertuccio, Fabien Boudia, M. Cambot, Cécile K. Lopez +14 more
2019HemaSphere16 citations Open access
Semantic Scholar
Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia
Allan Beke, L. Laplane, J. Rivière, Qin Yang +11 more
2019Haematologica16 citations Open access
Semantic Scholar
Lyl-1 regulates primitive macrophages and microglia development
Shoutang Wang, De-lian Ren, B. Arkoun, Anna-Lila Kaushik +7 more
2021Communications Biology12 citations Open access
Semantic Scholar
Dual role of EZH2 on megakaryocyte differentiation.
Stefania Mazzi, P. Dessen, Mathieu Vieira, Virginie Dufour +15 more
2021Blood12 citations Open access
Semantic Scholar
Recent advances in therapies for primary myelofibrosis
W. Vainchenker, N. Yahmi, V. Havelange, C. Marty +2 more
2023Faculty Reviews10 citations Open access
Semantic Scholar
A new efficient tool for non‐invasive diagnosis of fetomaternal platelet antigen incompatibility
Yasmine Ouzegdouh Mammasse, C. Chenet, D. Drubay, C. Martageix +3 more
2020British Journal of Haematology10 citations
Semantic Scholar
SF3B1 mutations in the Driver Clone Increase the Risk of Evolution to Myelofibrosis in Patients with Myeloproliferative Neoplasms (MPN)
Lin-Pierre Zhao, Rafael Daltro de Oliveira, C. Marcault, J. Soret +14 more
202010 citations
Semantic Scholar
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis
F. Basso-Valentina, A. Donada, V. Manchev, Manuel Lisetto +19 more
2022bioRxiv8 citations Open access
Semantic Scholar
CCND2 mutations are infrequent events in BCR-ABL1 negative myeloproliferative neoplasm patients
B. Cassinat, E. Verger, N. Maslah, N. Gauthier +3 more
2020Haematologica8 citations Open access
Semantic Scholar
An inherited gain‐of‐function risk allele in EPOR predisposes to familial JAK2V617F myeloproliferative neoplasms
Graciela Rabadan Moraes, Florence Pasquier, C. Marzac, E. Deconinck +11 more
2022British Journal of Haematology7 citations Open access
Semantic Scholar
PPAR-y agonists promote the resolution of myelofibrosis in preclinical models.
J. Lambert, Joseph Saliba, C. Calderón, K. Sii-Felice +12 more
2021Journal of Clinical Investigation7 citations Open access
Semantic Scholar
Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms
Lise Secardin, Cintia E. Gomez Limia, Suzana da Silva-Benedito, L. Lordier +10 more
2021HemaSphere6 citations Open access
Semantic Scholar
Megakaryocytes tame erythropoiesis with TGFβ1.
J. Villeval, W. Vainchenker
2020Blood6 citations
Semantic Scholar
TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells.
Lise Secardin, Cintia G. Limia, A. Di Stefano, M. Bonamino +9 more
2020Stem Cell Research6 citations Open access
Semantic Scholar
JAK Inhibition Mediates Clonal Selection of RAS Pathway Mutations in Myeloproliferative Neoplasms
N. Maslah, Blandine Roux, N. Kaci, E. Verger +17 more
2022Blood5 citations Open access
Semantic Scholar
CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag.
F. Basso-Valentina, G. Levy, Leila Varghese, M. Oufadem +10 more
2021Blood5 citations Open access
Semantic Scholar
The megakaryocyte: a cell with 3 faces as a mythic god?
W. Vainchenker, H. Raslova
2021Blood5 citations
Semantic Scholar
ATG2B/GSKIP in de novo acute myeloid leukemia (AML): high prevalence of germline predisposition in French West Indies
Jean Pegliasco, B. Schmaltz-Panneau, J. Martin, Samy Chraibi +23 more
2021Leukemia and Lymphoma5 citations
Semantic Scholar

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