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Y. Lécluse · SciRah

Researcher profile · Semantic Scholar

Y. Lécluse

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Y. Lécluse — researcher profile on SciRah

h-index: 40
Works: 104
Citations: 6,203

Most-cited papers

Mutation in TET2 in myeloid cancers.
F. Delhommeau, S. Dupont, V. Della Valle, C. James +19 more
2009New England Journal of Medicine1,729 citations Open access
Semantic Scholar
A novel dendritic cell subset involved in tumor immunosurveillance
J. Taieb, N. Chaput, C. Ménard, L. Apetoh +21 more
2006Nature Medicine462 citations
Semantic Scholar
The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera.
S. Dupont, A. Massé, C. James, I. Teyssandier +9 more
2007Blood208 citations
Semantic Scholar
The Cooperative Induction of Hypoxia-Inducible Factor-1α and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis12
M. Noman, Stéphanie Buart, J. van Pelt, C. Richon +13 more
2009Journal of Immunology190 citations Open access
Semantic Scholar
Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera.
V. Ugo, C. Marzac, I. Teyssandier, F. Larbret +4 more
2004Experimental Hematology190 citations Open access
Semantic Scholar
Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells.
M. Mitjavila-Garcia, Michel Cailleret, I. Godin, M. Nogueira +6 more
2002Development173 citations
Semantic Scholar
A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis.
Olena Klimchenko, M. Mori, A. Distefano, T. Langlois +6 more
2009Blood160 citations
Semantic Scholar
Determinants of urinary deoxynivalenol and de-epoxy deoxynivalenol in male farmers from Normandy, France.
P. Turner, R. Hopton, Y. Lécluse, K. White +2 more
2010Journal of Agricultural and Food Chemistry130 citations
Semantic Scholar
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models
C. Thiollier, Cécile K. Lopez, B. Gerby, C. Ignacimouttou +26 more
2012Journal of Experimental Medicine119 citations Open access
Semantic Scholar
Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice.
A. Foudi, P. Jarrier, Yan-Yan Zhang, M. Wittner +5 more
2006Blood118 citations
Semantic Scholar
Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells.
L. Garçon, C. Rivat, C. James, C. Lacout +5 more
2005Blood110 citations Open access
Semantic Scholar
Acquired Resistance Mutations to ALK Inhibitors Identified by Single Circulating Tumor Cell Sequencing in ALK-Rearranged Non–Small-Cell Lung Cancer
Emma Pailler, V. Faugeroux, M. Oulhen, L. Mezquita +12 more
2019Clinical Cancer Research109 citations
Semantic Scholar
Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis.
R. Chaligné, C. James, C. Tonetti, R. Besancenot +9 more
2007Blood108 citations
Semantic Scholar
A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation
R. Besancenot, R. Chaligné, C. Tonetti, F. Pasquier +5 more
2010PLoS Biology107 citations Open access
Semantic Scholar
The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation.
C. Capron, Y. Lécluse, Anna-Lila Kaushik, A. Foudi +11 more
2006Blood100 citations Open access
Semantic Scholar
Potentiation of radiation therapy by the oncolytic adenovirus dl1520 (ONYX-015) in human malignant glioma xenografts
B. Geoerger, J. Grill, P. Opolon, J. Morizet +6 more
2003British Journal of Cancer94 citations Open access
Semantic Scholar
NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Receptors1
Béatrice le Maux Chansac, A. Moretta, I. Vergnon, P. Opolon +6 more
2005Journal of Immunology92 citations Open access
Semantic Scholar
Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenotype in vitro
H. Moniz, M. Gastou, T. Leblanc, C. Hurtaud +12 more
2012Cell Death and Disease85 citations Open access
Semantic Scholar
Characterization of the t(14;18) BCL2-IGH Translocation in Farmers Occupationally Exposed to Pesticides
S. Roulland, P. Lebailly, Y. Lécluse, M. Briand +2 more
2004Cancer Research85 citations
Semantic Scholar
Agricultural exposures to carbamate herbicides and fungicides and central nervous system tumour incidence in the cohort AGRICAN.
C. Piel, C. Pouchieu, C. Carles, Béatrix Béziat +38 more
2019Environment International84 citations Open access
Semantic Scholar
ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway.
A. Hamai, F. Meslin, Houssem Benlalam, Abdelali Jalil +7 more
2008Cancer Research82 citations Open access
Semantic Scholar
Two Distinct Gb3/CD77 Signaling Pathways Leading to Apoptosis Are Triggered by Anti-Gb3/CD77 mAb and Verotoxin-1*
C. Tétaud, Thomas Falguières, K. Carlier, Y. Lécluse +7 more
2003Journal of Biological Chemistry80 citations Open access
Semantic Scholar
Exposure to pesticides in open-field farming in France.
P. Lebailly, V. Bouchart, I. Baldi, Y. Lécluse +3 more
2009Annals of Occupational Hygiene78 citations
Semantic Scholar
Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy
N. Vigneron, M. Meryet-Figuiere, Audrey Guttin, J. Issartel +14 more
2016Molecular Oncology76 citations Open access
Semantic Scholar
The formin DIAPH1 (mDia1) regulates megakaryocyte proplatelet formation by remodeling the actin and microtubule cytoskeletons.
Jia-Jia Pan, L. Lordier, D. Meyran, P. Rameau +8 more
2014Blood76 citations
Semantic Scholar
Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells
Yun-Gan Tao, Ping Zhang, V. Frascogna, Y. Lécluse +3 more
2007British Journal of Cancer75 citations Open access
Semantic Scholar
JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation.
R. Besancenot, Damien Roos-Weil, C. Tonetti, H. Abdelouahab +10 more
2014Blood63 citations Open access
Semantic Scholar
In Situ Sensory Adaptation of Tumor-Infiltrating T Lymphocytes to Peptide-MHC Levels Elicits Strong Antitumor Reactivity1
G. Dorothée, I. Vergnon, Faten El Hage, Béatrice le Maux Chansac +6 more
2005Journal of Immunology62 citations Open access
Semantic Scholar
Quantification of circulating mature endothelial cells using a whole blood four-color flow cytometric assay.
N. Jacques, N. Vimond, R. Conforti, F. Griscelli +5 more
2008JIM - Journal of Immunological Methods52 citations
Semantic Scholar
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene-driven myeloid leukemia.
Cécile K. Lopez, Esteve Noguera, V. Stavropoulou, E. Robert +32 more
2019Cancer Discovery49 citations Open access
Semantic Scholar
Rescue of Tumor-Infiltrating Lymphocytes from Activation-Induced Cell Death Enhances the Antitumor CTL Response in CD5-Deficient Mice
Mouna Tabbekh, K. Franciszkiewicz, H. Haouas, Y. Lécluse +3 more
2011Journal of Immunology49 citations
Semantic Scholar
Human CD5 Protects Circulating Tumor Antigen-Specific CTL from Tumor-Mediated Activation-Induced Cell Death1
G. Friedlein, Faten El Hage, I. Vergnon, C. Richon +7 more
2007Journal of Immunology48 citations
Semantic Scholar
Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process.
L. Lordier, Yun-Hua Chang, Abdelali Jalil, F. Aurade +8 more
2010Blood47 citations
Semantic Scholar
CD158 receptor controls cytotoxic T-lymphocyte susceptibility to tumor-mediated activation-induced cell death by interfering with Fas signaling.
A. Gati, N. Guerra, C. Gaudin, S. da Rocha +5 more
2003Cancer Research47 citations
Semantic Scholar
EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts
B. Geoerger, N. Gaspar, P. Opolon, J. Morizet +6 more
2008International Journal of Cancer46 citations Open access
Semantic Scholar
Bloom's syndrome protein response to ultraviolet-C radiation and hydroxyurea-mediated DNA synthesis inhibition
Mouna Ababou, Virginie Dumaire, Y. Lécluse, M. Amor-Guéret
2002Oncogene46 citations
Semantic Scholar
Mutant MyoD Lacking Cdc2 Phosphorylation Sites Delays M-Phase Entry
Lionel A. Tintignac, V. Sirri, M. Leibovitch, Y. Lécluse +4 more
2004Molecular and Cellular Biology43 citations Open access
Semantic Scholar
A major role of TGF-beta1 in the homing capacities of murine hematopoietic stem cell/progenitors.
C. Capron, C. Lacout, Y. Lécluse, V. Jalbert +6 more
2010Blood40 citations
Semantic Scholar
Expression of p53, or targeting towards EGFR, enhances the oncolytic potency of conditionally replicative adenovirus against neuroblastoma
B. Geoerger, V. V. van Beusechem, P. Opolon, J. Morizet +7 more
2005Journal of Gene Medicine36 citations
Semantic Scholar
Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms
A. Ali, O. Bluteau, K. Messaoudi, A. Palazzo +14 more
2013Cell Death and Disease35 citations Open access
Semantic Scholar
DNA damage in B and T lymphocytes of farmers during one pesticide spraying season
P. Lebailly, G. Mirey, F. Hérin, Y. Lécluse +2 more
2015International Archives of Occupational and Environmental Health29 citations Open access
Semantic Scholar
Increased risk of central nervous system tumours with carbamate insecticide use in the prospective cohort AGRICAN.
C. Piel, C. Pouchieu, Lucile Migault, Béatrix Béziat +36 more
2018International Journal of Epidemiology28 citations Open access
Semantic Scholar
Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: relationship to Bcl-2 family and caspase activation
A. Hamai, C. Richon, F. Meslin, F. Faure +7 more
2007Oncogene28 citations Open access
Semantic Scholar
Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: relationship to Bcl-2 family and caspase activation
A. Hamai, C. Richon, F. Meslin, F. Faure +7 more
2006Oncogene28 citations
Semantic Scholar
Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors
M. Oulhen, P. Pawlikowska, Tala Tayoun, Marianna Garonzi +11 more
2021npj Precision Oncology27 citations Open access
Semantic Scholar
Red cells exchanges in sickle cells disease lead to a selective reduction of erythrocytes‐derived blood microparticles
Emna Mahfoudhi, Y. Lécluse, F. Driss, S. Abbes +2 more
2012British Journal of Haematology24 citations Open access
Semantic Scholar
Expression of erythropoietin and its receptor in neuroblastomas
H. Sartelet, M. Fabre, M. Castaing, J. Bosq +7 more
2007Cancer23 citations Open access
Semantic Scholar
Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell Leukemia
Anouchka P. Laurent, Aurélie Siret, C. Ignacimouttou, Kunjal Panchal +26 more
2020Clinical Cancer Research22 citations Open access
Semantic Scholar
An innovative chemometric method for processing direct introduction high resolution mass spectrometry metabolomic data: independent component–discriminant analysis (IC–DA)
Baninia Habchi, S. Alves, Delphine Jouan-Rimbaud Bouveresse, Bilel Moslah +6 more
2017Metabolomics22 citations
Semantic Scholar
LYL-1 deficiency induces a stress erythropoiesis.
C. Capron, C. Lacout, Y. Lécluse, O. Wagner-Ballon +5 more
2011Experimental Hematology22 citations Open access
Semantic Scholar

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