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J. McVey · SciRah

Researcher profile · Semantic Scholar

J. McVey

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J. McVey — researcher profile on SciRah

h-index: 41
Works: 171
Citations: 6,053

Most-cited papers

Adenovirus serotype 5 hexon mediates liver gene transfer.
S. Waddington, J. McVey, D. Bhella, A. Parker +16 more
2008Cell672 citations Open access
Semantic Scholar
Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes.
A. Parker, S. Waddington, Campbell G. Nicol, D. Shayakhmetov +8 more
2006Blood319 citations Open access
Semantic Scholar
Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.
J. McIntosh, P. Lenting, Cecilia Rosales, Doyoung Lee +19 more
2013Blood279 citations Open access
Semantic Scholar
Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer.
R. Alba, A. Bradshaw, A. Parker, D. Bhella +8 more
2009Blood209 citations Open access
Semantic Scholar
Codon optimization of human factor VIII cDNAs leads to high-level expression.
N. Ward, S. Buckley, S. Waddington, T. VandenDriessche +7 more
2011Blood186 citations Open access
Semantic Scholar
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.
R. Alba, A. Bradshaw, L. Coughlan, L. Denby +12 more
2010Blood110 citations Open access
Semantic Scholar
A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome.
C. Albrecht, J. McVey, J. Elliott, A. Sardini +6 more
2005Blood103 citations Open access
Semantic Scholar
Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1–dependent leukocyte recruitment in vivo
Da-Xin Chen, A. Carpenter, J. Abrahams, R. Chambers +3 more
2008Journal of Experimental Medicine91 citations Open access
Semantic Scholar
Targeting of Adenovirus Serotype 5 (Ad5) and 5/47 Pseudotyped Vectors In Vivo: Fundamental Involvement of Coagulation Factors and Redundancy of CAR Binding by Ad5
S. Waddington, A. Parker, M. Havenga, S. Nicklin +3 more
2007Journal of Virology84 citations Open access
Semantic Scholar
Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer
A. Parker, S. Waddington, S. Buckley, Jerome Custers +6 more
2008Journal of Virology83 citations Open access
Semantic Scholar
Heme oxygenase (HO)‐1 induction prevents Endoplasmic Reticulum stress‐mediated endothelial cell death and impaired angiogenic capacity
H. Maamoun, Matshediso Zachariah, J. McVey, F. Green +1 more
2017Biochemical Pharmacology78 citations Open access
Semantic Scholar
The influence of blood on in vivo adenovirus bio-distribution and transduction.
A. Baker, J. McVey, S. Waddington, N. D. Di Paolo +1 more
2007Molecular Therapy78 citations Open access
Semantic Scholar
EXPRESSION OF TISSUE FACTOR AND INITIATION OF CLOTTING BY HUMAN PLATELETS AND MONOCYTES AFTER INCUBATION WITH PORCINE ENDOTHELIAL CELLS
Chih-Che Lin, Da-Xin Chen, J. McVey, D. Cooper +1 more
2008Transplantation70 citations Open access
Semantic Scholar
Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop.
A. Kritz, Campbell G. Nicol, Kate L. Dishart, R. Nelson +6 more
2007Molecular Therapy70 citations Open access
Semantic Scholar
In Vitro and In Vivo Properties of Adenovirus Vectors with Increased Affinity to CD46
Hong-Jie Wang, Ying Liu, Zong-Yi Li, S. Tuve +10 more
2008Journal of Virology69 citations Open access
Semantic Scholar
Influence of Coagulation Factor Zymogens on the Infectivity of Adenoviruses Pseudotyped with Fibers from Subgroup D
A. Parker, J. McVey, Jessica Doctor, Ó. López-Franco +4 more
2007Journal of Virology69 citations Open access
Semantic Scholar
The European Association for Haemophilia and Allied Disorders (EAHAD) Coagulation Factor Variant Databases: Important resources for haemostasis clinicians and researchers
J. McVey, Pavithra M. Rallapalli, G. Kemball-Cook, D. Hampshire +4 more
2020Haemophilia65 citations Open access
Semantic Scholar
Manipulating Adenovirus Hexon Hypervariable Loops Dictates Immune Neutralisation and Coagulation Factor X-dependent Cell Interaction In Vitro and In Vivo
Jiang-Tao Ma, M. Duffy, L. Deng, R. Dakin +6 more
2015PLoS Pathogens52 citations Open access
Semantic Scholar
AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage
C. Binny, J. McIntosh, M. della Peruta, H. Kymalainen +12 more
2011Blood50 citations Open access
Semantic Scholar
Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p.
L. Denby, Lorraine M. Work, D. V. Von Seggern, E. Wu +3 more
2007Molecular Therapy48 citations Open access
Semantic Scholar
Temporal expression of alternatively spliced forms of tissue factor pathway inhibitor in mice
S. Maroney, J. P. Ferrel, S. Pan, T. White +3 more
2009Journal of Thrombosis and Haemostasis47 citations Open access
Semantic Scholar
Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors.
Jenny A. Greig, S. Buckley, S. Waddington, A. Parker +7 more
2009Molecular Therapy45 citations Open access
Semantic Scholar
Nomenclature of genetic variants in hemostasis
A. Goodeve, P. Reitsma, J. McVey
2011Journal of Thrombosis and Haemostasis43 citations Open access
Semantic Scholar
Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy.
M. Di Matteo, E. Samara-Kuko, N. Ward, Simon N Waddingon +3 more
2014Molecular Therapy42 citations Open access
Semantic Scholar
The EAHAD blood coagulation factor VII variant database
M. Giansily-Blaizot, Pavithra M. Rallapalli, S. Perkins, G. Kemball-Cook +4 more
2020Human Mutation41 citations Open access
Semantic Scholar
In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression
A. Rahim, Andrew M. S. Wong, S. Ahmadi, K. Hoefer +7 more
2011Gene Therapy41 citations Open access
Semantic Scholar
Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions
Katie M. White, H. Büning, A. Kritz, H. Janicki +8 more
2008Gene Therapy41 citations
Semantic Scholar
Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE−/− Mice
Da-Xin Chen, Min Xia, C. Hayford, E. Tham +13 more
2015Circulation35 citations Open access
Semantic Scholar
A Cluster of Basic Amino Acids in the Factor X Serine Protease Mediates Surface Attachment of Adenovirus/FX Complexes
M. Duffy, A. Bradshaw, A. Parker, J. McVey +1 more
2011Journal of Virology35 citations Open access
Semantic Scholar
Clustered F8 missense mutations cause hemophilia A by combined alteration of splicing and protein biosynthesis and activity
Irving Donadon, J. McVey, I. Garagiola, A. Branchini +4 more
2017Haematologica30 citations Open access
Semantic Scholar
Pericytes’ Circadian Clock Affects Endothelial Cells’ Synchronization and Angiogenesis in a 3D Tissue Engineered Scaffold
V. Mastrullo, D. R. van der Veen, P. Gupta, R. Matos +5 more
2022Frontiers in Pharmacology28 citations Open access
Semantic Scholar
The role of the tissue factor pathway in haemostasis and beyond
J. McVey
2016Current opinion in hematology27 citations Open access
Semantic Scholar
Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34+ vascular progenitors.
Da-Xin Chen, J. Abrahams, Leanne M. Smith, J. McVey +2 more
2008Blood25 citations Open access
Semantic Scholar
Tissue factor initiated blood coagulation.
K. Gomez, J. McVey
2006Frontiers in Bioscience24 citations Open access
Semantic Scholar
Postinjury vascular intimal hyperplasia in mice is completely inhibited by CD34+ bone marrow‐derived progenitor cells expressing membrane‐tethered anticoagulant fusion proteins
Da-Xin Chen, Michele Weber, P. Shiels, Rong Dong +6 more
2006Journal of Thrombosis and Haemostasis19 citations Open access
Semantic Scholar
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function.
Silvia Lombardi, Gabriele Leo, S. Merlin, A. Follenzi +5 more
2021American Journal of Human Genetics15 citations Open access
Semantic Scholar
PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses
H. Wilkinson, Hugh Leonard, Da-Xin Chen, T. Lawrence +4 more
2021iScience14 citations Open access
Semantic Scholar
Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting
L. Lenaerts, J. McVey, Andrew H. Baker, L. Denby +3 more
2009Journal of Gene Medicine14 citations
Semantic Scholar
3D Printed Bioreactor Enabling the Pulsatile Culture of Native and Angioplastied Large Arteries
R. Matos, D. Maselli, J. McVey, C. Heiss +1 more
2022Frontiers in Cardiovascular Medicine12 citations Open access
Semantic Scholar
Age-Dependent Decline in Common Femoral Artery Flow-Mediated Dilation and Wall Shear Stress in Healthy Subjects
Mariam Bapir, Gavrielle R. Untracht, J. Hunt, J. McVey +8 more
2022Life12 citations Open access
Semantic Scholar
Cocoa flavanol consumption improves lower extremity endothelial function in healthy individuals and people with type 2 diabetes.
Mariam Bapir, Gavrielle R. Untracht, D. Cooke, J. McVey +8 more
2022Food & Function10 citations Open access
Semantic Scholar
Tissue Factor in the Myocardium: Evidence of Roles in Haemostasis and Inflammation
A. Mumford, J. McVey
2005Disease Markers10 citations Open access
Semantic Scholar
Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy
M. Di Matteo, E. Samara-Kuko, N. Ward, Simon N Waddingon +3 more
2014Molecular Therapy9 citations Open access
Semantic Scholar
The secretion efficiency of factor VIII can be regulated by the size and oligosaccharide content of the B domain.
S. Pipe, H. Miao, P. Kucab, J. McVey +1 more
20059 citations
Semantic Scholar
Inhibition of Angiopoietin-2 Production by Myofibrocytes Inhibits Neointimal Hyperplasia After Endoluminal Injury in Mice
Da-Xin Chen, Ke Li, E. Tham, Lin-Lin Wei +6 more
2018Frontiers in Immunology8 citations Open access
Semantic Scholar
Regression of Atherosclerosis in ApoE−/− Mice Via Modulation of Monocyte Recruitment and Phenotype, Induced by Weekly Dosing of a Novel “Cytotopic” Anti‐Thrombin Without Prolonged Anticoagulation
Da-Xin Chen, Ke Li, Sam Festenstein, J. Karegli +11 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease7 citations Open access
Semantic Scholar
The importance of tissue factor source in the management of Factor VII deficiency
P. Bolton-Maggs, Charles R. M. Hay, D. Shanks, M. Mitchell +1 more
2006Thrombosis and Haemostasis6 citations
Semantic Scholar
Manipulation of tissue factor-mediated basal PAR-2 signalling on macrophages determines sensitivity for IFNγ responsiveness and significantly modifies the phenotype of murine DTH
H. Wilkinson, Hugh Leonard, M. Robson, Richard Smith +5 more
2022Frontiers in Immunology5 citations Open access
Semantic Scholar
Impaired platelet‐dependent thrombin generation associated with thrombocytopenia is improved by prothrombin complex concentrates in vitro
P. Chowdary, C. Hamid, D. Slatter, Richard Morris +6 more
2020Research and Practice in Thrombosis and Haemostasis5 citations Open access
Semantic Scholar
In Vitro and In Vivo Properties of Adenovirus Vectors with Increased Affinity to CD 46
Hong-Jie Wang, Ying Liu, Zong-Yi Li, S. Tuve +10 more
20085 citations
Semantic Scholar

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