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Jenny A. Greig · SciRah

Researcher profile · Semantic Scholar

Jenny A. Greig

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Jenny A. Greig — researcher profile on SciRah

h-index: 22
Works: 51
Citations: 2,148

Most-cited papers

Adenovirus serotype 5 hexon mediates liver gene transfer.
S. Waddington, J. McVey, D. Bhella, A. Parker +16 more
2008Cell672 citations Open access
Semantic Scholar
Dynamic Changes in Lung MicroRNA Profiles During the Development of Pulmonary Hypertension due to Chronic Hypoxia and Monocrotaline
P. Caruso, M. MacLean, R. Khanin, J. McClure +11 more
2010Arteriosclerosis, Thrombosis and Vascular Biology345 citations Open access
Semantic Scholar
Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration
Jenny A. Greig, Kelly M. Martins, Camilo Breton, R. J. Lamontagne +10 more
2023Nature Biotechnology116 citations Open access
Semantic Scholar
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.
R. Alba, A. Bradshaw, L. Coughlan, L. Denby +12 more
2010Blood110 citations Open access
Semantic Scholar
High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury.
J. Hordeaux, R. J. Lamontagne, Chun-Juan Song, G. Buchlis +8 more
2024Molecular Therapy56 citations Open access
Semantic Scholar
Intramuscular Injection of AAV8 in Mice and Macaques Is Associated with Substantial Hepatic Targeting and Transgene Expression
Jenny A. Greig, Hui Peng, J. Ohlstein, C. A. Medina-Jaszek +8 more
2014PLoS ONE56 citations Open access
Semantic Scholar
Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR+/− Rhesus Macaques
Jenny A. Greig, M. Limberis, Peter Bell, Shu-Jen Chen +3 more
2017Human Gene Therapy Clinical Development54 citations Open access
Semantic Scholar
Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications
L. Amini, Jenny A. Greig, M. Schmueck-Henneresse, H. Volk +5 more
2021Frontiers in Immunology53 citations Open access
Semantic Scholar
ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing
Camilo Breton, Peter M. Clark, Lili Wang, Jenny A. Greig +1 more
2020BMC Genomics51 citations Open access
Semantic Scholar
Intramuscular administration of AAV overcomes pre-existing neutralizing antibodies in rhesus macaques.
Jenny A. Greig, R. Calcedo, R. Grant, Hui Peng +6 more
2016Vaccine49 citations Open access
Semantic Scholar
Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors.
N. Kane, A. Nowrouzi, S. Mukherjee, M. Blundell +9 more
2010Molecular Therapy46 citations Open access
Semantic Scholar
Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors.
Jenny A. Greig, S. Buckley, S. Waddington, A. Parker +7 more
2009Molecular Therapy45 citations Open access
Semantic Scholar
Intranasal gene therapy to prevent infection by SARS-CoV-2 variants
J. Sims, Jenny A. Greig, K. T. Michalson, Sharon Lian +11 more
2021bioRxiv41 citations Open access
Semantic Scholar
Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia
Jenny A. Greig, M. Limberis, Peter Bell, Shu-Jen Chen +3 more
2017Human Gene Therapy Clinical Development38 citations Open access
Semantic Scholar
Development of therapeutic anti-JAGGED1 antibodies for cancer therapy
M. Masiero, De-Min Li, P. Whiteman, C. Bentley +16 more
2019Molecular Cancer Therapeutics37 citations Open access
Semantic Scholar
Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy.
De-Min Li, C. Bentley, Amanda P. Anderson, S. Wiblin +12 more
2017Cancer Research36 citations Open access
Semantic Scholar
Characterization of Adeno-Associated Viral Vector-Mediated Human Factor VIII Gene Therapy in Hemophilia A Mice
Jenny A. Greig, Qiang Wang, Amanda L. Reicherter, Shu-Jen Chen +6 more
2017Human Gene Therapy34 citations
Semantic Scholar
Prevalent and Disseminated Recombinant and Wild-Type Adeno-Associated Virus Integration in Macaques and Humans
Kelly M. Martins, Camilo Breton, Qi Zheng, Zhe Zhang +3 more
2023Human Gene Therapy28 citations Open access
Semantic Scholar
A Gene Therapy Approach to Improve Copper Metabolism and Prevent Liver Damage in a Mouse Model of Wilson Disease
Jenny A. Greig, J. Nordin, Melanie K. Smith, Scott N. Ashley +5 more
2019Human Gene Therapy Clinical Development25 citations
Semantic Scholar
Muscle-directed Gene Therapy for Hemophilia B with More Efficient and Less Immunogenic AAV Vectors
Lili Wang, J. Louboutin, Peter Bell, Jenny A. Greig +3 more
2011Journal of Thrombosis and Haemostasis24 citations Open access
Semantic Scholar
Increasing the specificity of AAV-based gene editing through self-targeting and short promoter strategies.
Camilo Breton, T. Furmanak, Alexa N. Avitto, Melanie K. Smith +4 more
2020Molecular Therapy23 citations Open access
Semantic Scholar
AAV8 Gene Therapy Rescues the Newborn Phenotype of a Mouse Model of Crigler–Najjar
Jenny A. Greig, J. Nordin, C. Draper, Peter Bell +1 more
2018Human Gene Therapy22 citations
Semantic Scholar
Optimized Adeno-Associated Viral-Mediated Human Factor VIII Gene Therapy in Cynomolgus Macaques
Jenny A. Greig, J. Nordin, John White, Qiang Wang +6 more
2018Human Gene Therapy21 citations
Semantic Scholar
Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria.
Scott N. Ashley, J. Nordin, E. Buza, Jenny A. Greig +1 more
2018Molecular Genetics and Metabolism21 citations
Semantic Scholar
Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques
Jenny A. Greig, J. Nordin, Erin Bote, L. Makaron +5 more
2016Molecular Therapy: Methods & Clinical Development18 citations Open access
Semantic Scholar
Muscle-directed AAV gene therapy rescues the maple syrup urine disease phenotype in a mouse model.
Jenny A. Greig, Matthew Jennis, Aditya Dandekar, Joanna K Chorazeczewski +4 more
2021Molecular Genetics and Metabolism16 citations
Semantic Scholar
AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver
Jenny A. Greig, R. Calcedo, L. Kuri-Cervantes, J. Nordin +8 more
2018Molecular Therapy: Methods & Clinical Development16 citations Open access
Semantic Scholar
Vascular-Targeting Antioxidant Therapy in a Model of Hypertension and Stroke
Jenny A. Greig, R. Shirley, D. Graham, L. Denby +3 more
2010Journal of Cardiovascular Pharmacology15 citations
Semantic Scholar
Lipid nanoparticle-encapsulated mRNA therapy corrects serum total bilirubin level in Crigler-Najjar syndrome mouse model
Jenny A. Greig, Joanna K Chorazeczewski, Vivek K. Chowdhary, Melanie K. Smith +6 more
2023Molecular Therapy: Methods & Clinical Development12 citations Open access
Semantic Scholar
Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques
Alexander Kistner, Jessica A. Chichester, Lili Wang, R. Calcedo +11 more
2023Gene Therapy12 citations Open access
Semantic Scholar
Engineering chimeric human and mouse major histocompatibility complex (MHC) class I tetramers for the production of T-cell receptor (TCR) mimic antibodies
De-Min Li, C. Bentley, J. Yates, M. Salimi +4 more
2017PLoS ONE12 citations Open access
Semantic Scholar
Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors
M. Horiuchi, Christian J. Hinderer, Jenny A. Greig, Cecilia Dyer +7 more
2022Molecular Therapy: Methods & Clinical Development9 citations Open access
Semantic Scholar
Determining the Minimally Effective Dose of a Clinical Candidate AAV Vector in a Mouse Model of Crigler-Najjar Syndrome
Jenny A. Greig, J. Nordin, C. Draper, Deirdre McMenamin +5 more
2018Molecular Therapy: Methods & Clinical Development9 citations Open access
Semantic Scholar
Lipid Nanoparticle mRNA Therapy Improves Survival and Reduces Serum Branched-Chain Amino Acids in Mouse Models of Maple Syrup Urine Disease
Jenny A. Greig, Matthew Jennis, Aditya Dandekar, Joanna K Chorazeczewski +9 more
2024Human Gene Therapy8 citations
Semantic Scholar
Loss of transgene expression limits liver gene therapy in primates
Jenny A. Greig, Camilo Breton, Kelly M. Martins, Yanqing Zhu +5 more
2022bioRxiv7 citations Open access
Semantic Scholar
Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases
Jenny A. Greig, Camilo Breton, Scott N. Ashley, Kelly M. Martins +16 more
2022Human Gene Therapy6 citations
Semantic Scholar
Adeno-associated virus-mediated trastuzumab delivery to the central nervous system for human epidermal growth factor receptor 2+ brain metastasis
M. Werner, S. Aras, Ashleigh R. Morgan, Jillian Roamer +5 more
2024Cancer Gene Therapy2 citations
Semantic Scholar
Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A
Jenny A. Greig, Melanie K. Smith, J. Nordin, Tamara Goode +6 more
2021Human Gene Therapy2 citations Open access
Semantic Scholar
Correction to: ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing
Camilo Breton, Peter M. Clark, Lili Wang, Jenny A. Greig +1 more
2020BMC Genomics2 citations Open access
Semantic Scholar
Abstract LB201: Optimizing adeno-associated viral vector-mediated delivery of trastuzumab to the central nervous system for the treatment of Her2 positive brain metastasis
M. Werner, S. Aras, Ashleigh R. Morgan, N. Param +2 more
2022Cancer Research1 citations
Semantic Scholar
Biodistribution and retargeting of FX-binding ablated Ad5 vectors
R. Alba, A. Bradshaw, L. Coughlan, L. Denby +11 more
20101 citations
Semantic Scholar
In Vivo Genome Editing Approach to Disrupt Hydroxyacid Oxidase 1 for the Treatment of Primary Hyperoxaluria Type 1
Jenny A. Greig, Camilo Breton, Melanie K. Smith, T. Furmanak +3 more
2026Human Gene Therapy0 citations
Semantic Scholar
TBG . mLDLR and AAV 8 . TBG . hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia
Jenny A. Greig, M. Limberis, Peter Bell, Shu-Jen Chen +3 more
20170 citations
Semantic Scholar
760. Optimized AAV-Mediated Human Factor VIII Gene Therapy in Hemophilia A Mice and Cynomolgus Macaques
Jenny A. Greig, Qiang Wang, Amanda L. Reicherter, Erin Bote +9 more
20160 citations Open access
Semantic Scholar
Abstract C128: Development of therapeutic anti-Jagged1 monoclonal antibodies
M. Masiero, De-Min Li, P. Whiteman, C. Bentley +10 more
20150 citations
Semantic Scholar
Transgenic ablation system mediated inducible adeno-associated virus
James M. Wilson, A. Tretiakova, Jenny A. Greig
20120 citations
Semantic Scholar
Induction of iPS cells from Dermal Fibroblasts by High Dose HIV-Based LV Vectors in the Absence of Reprogramming Factors: Analysis of Integration Sites and Genomic Stability
N. Kane, A. Nowrouzi, Jenny A. Greig, Houslay +6 more
20100 citations
Semantic Scholar
Erratum: "Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors" (Molecular Theraphy (2009) 10.1038/mt.2009.152)
Jenny A. Greig, S. Buckley, S. Waddington, A. Parker +7 more
20090 citations
Semantic Scholar
Targeted delivery of biological agents.
Jenny A. Greig
20090 citations
Semantic Scholar
Influence of factor X on in vitro and in vivo gene delivery by Ad5 and Ad35 vectors
Jenny A. Greig, S. Buckley, S. Waddington, A. Parker +8 more
20090 citations Open access
Semantic Scholar

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