Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Da-Xin Chen · SciRah

Researcher profile · Semantic Scholar

Da-Xin Chen

Share profile

Da-Xin Chen — researcher profile on SciRah

h-index: 25
Works: 81
Citations: 1,995

Most-cited papers

Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice.
J. Tsang, Y. Tanriver, Shui-Ping Jiang, S. Xue +6 more
2008Journal of Clinical Investigation277 citations Open access
Semantic Scholar
Regulation of Phosphatidylinositol 3′-Kinase by Tyrosyl Phosphoproteins
T. Rordorf-Nikolic, D. J. van Horn, Da-Xin Chen, M. White +1 more
1995Journal of Biological Chemistry237 citations Open access
Semantic Scholar
Critical roles for thrombin in acute and chronic inflammation
Da-Xin Chen, A. Dorling
2009Journal of Thrombosis and Haemostasis122 citations Open access
Semantic Scholar
Sickle erythrocyte-endothelial interactions in microcirculation: the role of von Willebrand factor and implications for vasoocclusion.
D. Kaul, Ronald L. Nagel, Da-Xin Chen, Han-Mou Tsai
1993Blood102 citations Open access
Semantic Scholar
Complete Inhibition of Acute Humoral Rejection Using Regulated Expression of Membrane‐tethered Anticoagulants on Xenograft Endothelium
Da-Xin Chen, Michèle Weber, John H. McVey, G. Kemball-Cook +3 more
2004American Journal of Transplantation99 citations Open access
Semantic Scholar
Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1–dependent leukocyte recruitment in vivo
Da-Xin Chen, A. Carpenter, J. Abrahams, R. Chambers +3 more
2008Journal of Experimental Medicine91 citations Open access
Semantic Scholar
Adhesion of sickle cells to vascular endothelium is critically dependent on changes in density and shape of the cells.
D. Kaul, Da-Xin Chen, Jie Zhan
1994Blood88 citations
Semantic Scholar
Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways
James McIlroy, Da-Xin Chen, C. Wjasow, Tamar Michaeli +1 more
1997Molecular and Cellular Biology77 citations Open access
Semantic Scholar
In Vitro Expansion Improves In Vivo Regulation by CD4+CD25+ Regulatory T Cells1
Jian-Guo Chai, D. Coe, Da-Xin Chen, E. Simpson +2 more
2008Journal of Immunology72 citations Open access
Semantic Scholar
EXPRESSION OF TISSUE FACTOR AND INITIATION OF CLOTTING BY HUMAN PLATELETS AND MONOCYTES AFTER INCUBATION WITH PORCINE ENDOTHELIAL CELLS
Chih-Che Lin, Da-Xin Chen, J. McVey, D. Cooper +1 more
2008Transplantation70 citations Open access
Semantic Scholar
Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium.
Da-Xin Chen, Konstantinos Giannopoulos, P. Shiels, Zoe Webster +6 more
2004Blood56 citations
Semantic Scholar
TRANSFERRIN RECEPTOR-MEDIATED GENE TRANSFER TO THE CORNEAL ENDOTHELIUM1
P. Tan, W. J. King, Da-Xin Chen, H. Awad +5 more
2001Transplantation52 citations Open access
Semantic Scholar
Regulated inhibition of coagulation by porcine endothelial cells expressing P-selectin-tagged hirudin and tissue factor pathway inhibitor fusion proteins.
Da-Xin Chen, Kristian Riesbeck, John H. McVey, G. Kemball-Cook +3 more
1999Transplantation50 citations Open access
Semantic Scholar
Immunization with a combination of ApoB and HSP60 epitopes significantly reduces early atherosclerotic lesion in Apobtm2SgyLdlrtm1Her/J mice.
Xin-Jie Lu, Da-Xin Chen, V. Endrész, Min Xia +7 more
2010Atherosclerosis42 citations
Semantic Scholar
Inhibition of tissue factor-dependent and -independent coagulation by cell surface expression of novel anticoagulant fusion proteins.
Da-Xin Chen, Kristian Riesbeck, G. Kemball-Cook, John H. McVey +3 more
1999Transplantation36 citations Open access
Semantic Scholar
Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE−/− Mice
Da-Xin Chen, Min Xia, C. Hayford, E. Tham +13 more
2015Circulation35 citations Open access
Semantic Scholar
Mucosal Tolerance to a Combination of ApoB and HSP60 Peptides Controls Plaque Progression and Stabilizes Vulnerable Plaque in Apobtm2SgyLdlrtm1Her/J Mice
Lakshmi A Mundkur, R. Mukhopadhyay, Sonia K. Samson, M. Varma +7 more
2013PLoS ONE35 citations Open access
Semantic Scholar
Expression of hirudin fusion proteins in mammalian cells: a strategy for prevention of intravascular thrombosis.
K. Riesbeck, Da-Xin Chen, G. Kemball-Cook, John H. McVey +4 more
1998Circulation35 citations Open access
Semantic Scholar
NK‐cell‐dependent acute xenograft rejection in the mouse heart‐to‐rat model
Da-Xin Chen, Michèle Weber, R. Lechler, A. Dorling
2006Xenotransplantation32 citations
Semantic Scholar
Helicobacter pylori induces in‐vivo expansion of human regulatory T cells through stimulating interleukin‐1β production by dendritic cells
P. Mitchell, Ben Afzali, H. Fazekasova, Da-Xin Chen +5 more
2012Clinical and Experimental Immunology31 citations Open access
Semantic Scholar
Protective Role of C3aR (C3a Anaphylatoxin Receptor) Against Atherosclerosis in Atherosclerosis-Prone Mice
Lin-Lin Wei, Ning Ma, Kun-Yi Wu, Jia-Xing Wang +8 more
2020Arteriosclerosis, Thrombosis and Vascular Biology29 citations Open access
Semantic Scholar
Impact of multiple antigenic epitopes from ApoB100, hHSP60 and Chlamydophila pneumoniae on atherosclerotic lesion development in Apob(tm2Sgy)Ldlr(tm1Her)J mice.
Xin-Jie Lu, Min Xia, V. Endrész, Ildikó Faludi +5 more
2012Atherosclerosis29 citations Open access
Semantic Scholar
Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif
Da-Xin Chen, D. J. van Horn, M. White, J. Backer
1995Molecular and Cellular Biology28 citations Open access
Semantic Scholar
Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34+ vascular progenitors.
Da-Xin Chen, J. Abrahams, Leanne M. Smith, J. McVey +2 more
2008Blood25 citations Open access
Semantic Scholar
Human thrombin and FXa mediate porcine endothelial cell activation; modulation by expression of TFPI‐CD4 and hirudin‐CD4 fusion proteins
Da-Xin Chen, K. Riesbeck, John H. McVey, G. Kemball-Cook +3 more
2001Xenotransplantation25 citations
Semantic Scholar
Donor HO-1 Expression Inhibits Intimal Hyperplasia in Unmanipulated Graft Recipients: A Potential Role for CD8+ T-Cell Modulation by Carbon Monoxide
H. Clarke, S. Shrivastava, R. Motterlini, Philip Sawle +2 more
2009Transplantation22 citations Open access
Semantic Scholar
Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
Jian Lou, Yue Hu, Min-Dan Wu, Luan-qing Che +15 more
2018Acta Pharmacologica Sinica21 citations Open access
Semantic Scholar
Postinjury vascular intimal hyperplasia in mice is completely inhibited by CD34+ bone marrow‐derived progenitor cells expressing membrane‐tethered anticoagulant fusion proteins
Da-Xin Chen, Michele Weber, P. Shiels, Rong Dong +6 more
2006Journal of Thrombosis and Haemostasis19 citations Open access
Semantic Scholar
Microcoagulation processes after xenotransplantation
Da-Xin Chen, A. Dorling
200519 citations
Semantic Scholar
Immunization With a Combination of 2 Peptides Derived From the C5a Receptor Significantly Reduces Early Atherosclerotic Lesion in Ldlrtm1Her Apobtm2Sgy J Mice
Xin-Jie Lu, Min Xia, V. Endrész, Ildikó Faludi +4 more
2012Arteriosclerosis, Thrombosis and Vascular Biology16 citations Open access
Semantic Scholar
PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses
H. Wilkinson, Hugh Leonard, Da-Xin Chen, T. Lawrence +4 more
2021iScience14 citations Open access
Semantic Scholar
Pancreatic-Derived Pathfinder Cells Enable Regeneration of Critically Damaged Adult Pancreatic Tissue and Completely Reverse Streptozotocin-Induced Diabetes
K. Stevenson, Da-Xin Chen, A. Macintyre, L. Mcglynn +8 more
2011Rejuvenation Research14 citations
Semantic Scholar
Protease‐activated receptor‐2 signalling by tissue factor on dendritic cells suppresses antigen‐specific CD4+ T‐cell priming
S. Shrivastava, Liang Ma, E. Tham, John H. McVey +2 more
2013Immunology12 citations Open access
Semantic Scholar
Fibrocytes mediate intimal hyperplasia post‐vascular injury and are regulated by two tissue factor‐dependent mechanisms
Da-Xin Chen, Liang Ma, E. Tham, S. Maresh +3 more
2013Journal of Thrombosis and Haemostasis12 citations Open access
Semantic Scholar
Research progress on the regulatory effects of Chinese food and medicine homology on type 1 diabetes mellitus
Pingduo Chen, Jingjing Li, Shan Zhang, Da-Xin Chen +7 more
2025Food & Medicine Homology11 citations Open access
Semantic Scholar
Inhibition of Thrombin Receptor Signaling on &agr;-Smooth Muscle Actin+ CD34+ Progenitors Leads to Repair After Murine Immune Vascular Injury
Da-Xin Chen, S. Shrivastava, Liang Ma, E. Tham +6 more
2012Arteriosclerosis, Thrombosis and Vascular Biology11 citations Open access
Semantic Scholar
Inhibition of Angiopoietin-2 Production by Myofibrocytes Inhibits Neointimal Hyperplasia After Endoluminal Injury in Mice
Da-Xin Chen, Ke Li, E. Tham, Lin-Lin Wei +6 more
2018Frontiers in Immunology8 citations Open access
Semantic Scholar
Regression of Atherosclerosis in ApoE−/− Mice Via Modulation of Monocyte Recruitment and Phenotype, Induced by Weekly Dosing of a Novel “Cytotopic” Anti‐Thrombin Without Prolonged Anticoagulation
Da-Xin Chen, Ke Li, Sam Festenstein, J. Karegli +11 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease7 citations Open access
Semantic Scholar
Generation of a polyclonal rabbit anti-mouse tissue factor antibody by nucleic acid immunisation
A. Mumford, Da-Xin Chen, A. Dorling, G. Kemball-Cook +1 more
2004Thrombosis and Haemostasis6 citations Open access
Semantic Scholar
Manipulation of tissue factor-mediated basal PAR-2 signalling on macrophages determines sensitivity for IFNγ responsiveness and significantly modifies the phenotype of murine DTH
H. Wilkinson, Hugh Leonard, M. Robson, Richard Smith +5 more
2022Frontiers in Immunology5 citations Open access
Semantic Scholar
DEVELOPING A PORCINE TRANSPLANTATION MODEL: EFFICIENT GENE TRANSFER INTO PORCINE VASCULAR CELLS
Da-Xin Chen, F. Morgan, I. Berton, P. Herbert +4 more
2004Transplantation5 citations Open access
Semantic Scholar
Modulation of Recombinant Antigenic Constructs Containing Multi-Epitopes towards Effective Reduction of Atherosclerotic Lesion in B6;129S-Ldlrtm1HerApobtm2Sgy/J Mice
Min Xia, Da-Xin Chen, V. Endrész, I. Lantos +3 more
2015PLoS ONE4 citations Open access
Semantic Scholar
Immunization of Chlamydia pneumoniae (Cpn)-Infected Apobtm2SgyLdlrtm1Her/J Mice with a Combined Peptide of Cpn Significantly Reduces Atherosclerotic Lesion Development
Min Xia, Da-Xin Chen, V. Endrész, Ildikó Faludi +4 more
2013PLoS ONE4 citations Open access
Semantic Scholar
THE RECEPTOR FOR COMPLEMENT COMPONENT C3A MEDIATES PROTECTION FROM THE DEVELOPMENT OF ATHEROSCLEROSIS IN APOLIPOPROTEIN E DEFICIENT (APOE-/-) MICE
Lin-Lin Wei, Ning Ma, Yafeng Gao, Jia-Xing Wang +3 more
20183 citations Open access
Semantic Scholar
Enhanced effect of inhibition of thrombin on endothelium in murine endotoxaemia: specific inhibition of thrombocytopenia.
Da-Xin Chen, J. McVey, A. Dorling
2013Thrombosis Research3 citations Open access
Semantic Scholar
Correction: Immunization of Chlamydia pneumoniae (Cpn)-Infected Apobtm2SgyLdlrtm1Her/J Mice with a Combined Peptide of Cpn Significantly Reduces Atherosclerotic Lesion Development
Min Xia, Da-Xin Chen, V. Endrész, Ildikó Faludi +1 more
2014PLoS ONE2 citations Open access
Semantic Scholar
EXPRESSION OF NOVEL ANTICOAGULANT FUSION PROTEINS INHIBITS FACTOR XA‐ AND THROMBIN‐INDUCED ACTIVATION OF PORCINE VASCULAR ENDOTHELIAL CELLS.: Abstract# 1042
Da-Xin Chen, K. Riesbeck, J. McVey, G. Kemball-Cook +3 more
20002 citations Open access
Semantic Scholar
Successful in vivo transfection of non-dividing endothelium by DAPI-supplemented liposome-packaged DNA
Da-Xin Chen, I. Berton, P. Herbert, M. F. Morgan +4 more
20031 citations
Semantic Scholar
Regulated endothelial cell expression of novel anticoagulants: a strategy for the prevention and therapy of intravascular thrombosis.
Anthony Dorling, Da-Xin Chen, Kristian Riesbeck, John H. McVey +3 more
2000Transplantation Proceedings1 citations
Semantic Scholar
S21.3. Platelet-activating factor increases adhesion of sickle erythrocytes to vascular endothelium by a vascular integrinαβ and von Willebrand factor-dependent mechanism
D. Kaul, H. Tsai, R. Nagel, Da-Xin Chen
19951 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

A. Dorling×24
Invite
A. Dorling — researcher profile on SciRah
J. McVey×13
Invite
J. McVey — researcher profile on SciRah
R. Lechler×11
Invite
R. Lechler — researcher profile on SciRah
G. Kemball-Cook×10
Invite
G. Kemball-Cook — researcher profile on SciRah

×9

Invite

E. Tuddenham — researcher profile on SciRah

John H. McVey×8

Invite

John H. McVey — researcher profile on SciRah

Invite

Min Xia — researcher profile on SciRah

Invite

R. Lechler — researcher profile on SciRah

Invite

V. Kakkar — researcher profile on SciRah

Invite

Xin-Jie Lu — researcher profile on SciRah

Invite

V. Endrész — researcher profile on SciRah

Ildikó Faludi×5

Invite

Ildikó Faludi — researcher profile on SciRah