Researcher profile · Semantic Scholar

P. Grothaus

h-index: 18
Works: 43
Citations: 3,258

Most-cited papers

Impact of natural products on developing new anti-cancer agents.
G. Cragg, P. Grothaus, D. Newman
2009Chemical Reviews1,237 citations
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Discovery of Selective Irreversible Inhibitors for Bruton’s Tyrosine Kinase
Z. Pan, H. Scheerens, Shyr-Jiann Li, B. Schultz +12 more
2007ChemMedChem670 citations
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The search for a taxol-producing microorganism among the endophytic fungi of the Pacific yew, Taxus brevifolia.
A. Stierle, G. Strobel, D. Stierle, P. Grothaus +1 more
1995Journal of Natural Products255 citations
Semantic Scholar
New horizons for old drugs and drug leads.
G. Cragg, P. Grothaus, D. Newman
2014Journal of Natural Products229 citations
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NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening
C. Thornburg, J. R. Britt, Jason R. Evans, R. Akee +11 more
2018ACS Chemical Biology149 citations Open access
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An enzyme immunoassay for the determination of taxol and taxanes in Taxus sp. tissues and human plasma.
P. Grothaus, T. J. Raybould, G. Bignami, Carolyn B. Lazo +1 more
1993JIM - Journal of Immunological Methods77 citations
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Asymmetric microbial reduction of prochiral 2,2,-disubstituted cycloalkanediones
D. W. Brooks, H. Mazdiyasni, P. Grothaus
198772 citations
Semantic Scholar
Plant Natural Products in Anticancer Drug Discovery
P. Grothaus, G. Cragg, D. Newman
201068 citations
Semantic Scholar
Development of activity-based probes for trypsin-family serine proteases.
Z. Pan, D. Jeffery, K. Chehade, J. Beltman +4 more
2006Bioorganic & Medicinal Chemistry Letters68 citations Open access
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Impact of Natural Products on Developing New Anticancer Agents
G. Cragg, P. Grothaus, D. Newman
200958 citations
Semantic Scholar
Monoclonal antibody-based enzyme-linked immunoassays for the measurement of palytoxin in biological samples.
G. Bignami, T. J. Raybould, N. Sachinvala, P. Grothaus +5 more
1992Toxicon58 citations
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A monoclonal antibody‐based immunoassay for detecting tetrodotoxin in biological samples
T. J. Raybould, G. Bignami, L. Inouye, Samantha B. Simpson +3 more
1992Journal of clinical laboratory analysis (Print)50 citations
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Total synthesis of the trichothecene mycotoxin anguidine
D. W. Brooks, P. Grothaus, H. Mazdiyasni
198346 citations
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N-(4'-hydroxyphenylacetyl)palytoxin: a palytoxin prodrug that can be activated by a monoclonal antibody-penicillin G amidase conjugate.
G. Bignami, P. Senter, P. Grothaus, K. Fischer +2 more
1992Cancer Research45 citations
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CHIRAL CYCLOPENTANOID SYNTHETIC INTERMEDIATES VIA ASYMMETRIC MICROBIAL REDUCTION OF PROCHIRAL 2,2-DISUBSTITUTED CYCLOPENTANEDIONES
D. W. Brooks, P. Grothaus, William L. Irwin
198239 citations
Semantic Scholar
Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and "total taxanes" in Taxus brevifolia extracts by enzyme immunoassay.
P. Grothaus, G. Bignami, S. O'Malley, Kent E. Harada +5 more
1995Journal of Natural Products36 citations
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Synthetic studies of trichothecenes, an enantioselective synthesis of a C-ring precursor of anguidine
D. W. Brooks, P. Grothaus, J. T. Palmer
198224 citations
Semantic Scholar
Bioactive metabolites of the endophytic fungi of Pacific yew, Taxus brevifolia: paclitaxel, taxanes, and other bioactive compounds
A. Stierle, D. Stierle, G. Strobel, G. Bignami +1 more
199519 citations
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Biological activity of 26-succinylbryostatin 1.
G. Bignami, F. Wagner, P. Grothaus, P. Rustagi +2 more
1996Biochimica et Biophysica Acta12 citations Open access
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Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens
Tanja Grkovic, Jason R. Evans, R. Akee, Liang-Hui Guo +8 more
2018Bioorganic & Medicinal Chemistry Letters10 citations Open access
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Natural Products in Drug Discovery: Recent Advances
G. Cragg, P. Grothaus, D. Newman
201210 citations
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Microbial Coculture and OSMAC Approach as Strategies to Induce Cryptic Fungal Biogenetic Gene Clusters
D. Newman, G. Cragg, P. Grothaus
20175 citations
Semantic Scholar
Microbial Genome Mining for Natural Product Drug Discovery
D. Newman, G. Cragg, P. Grothaus
20175 citations
Semantic Scholar
Identification of metabolites of the tryptase inhibitor CRA-9249: observation of a metabolite derived from an unexpected hydroxylation pathway.
Walter Yu, J. Dener, D. Dickman, P. Grothaus +11 more
2006Bioorganic & Medicinal Chemistry Letters5 citations Open access
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An enzyme immunoassay for determining plasma concentrations of didemnin B
T. J. Raybould, P. Grothaus, Samantha B. Simpson, G. Bignami +2 more
1992Journal of clinical laboratory analysis (Print)5 citations
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A New Bispyrroloiminoquinone Alkaloid From a Thai Collection of Clavelina sp.
Tanja Grkovic, S. Ruchirawat, P. Kittakoop, P. Grothaus +5 more
2021Asian Journal of Organic Chemistry3 citations
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The Role of Combinatorial Biosynthesis in Natural Products Discovery
D. Newman, G. Cragg, P. Grothaus
20172 citations
Semantic Scholar
Chemical Biology of Natural Products
D. Newman, G. Cragg, P. Grothaus
20191 citations
Semantic Scholar
Chemical Biology of Marine Cyanobacteria
D. Newman, G. Cragg, P. Grothaus
20171 citations
Semantic Scholar
Novel Insights in Plant-Endophyte Interactions
D. Newman, G. Cragg, P. Grothaus
20171 citations
Semantic Scholar
Novel Metabolites from Extremophilic Microbes Isolated from Toxic Waste Sites
D. Newman, G. Cragg, P. Grothaus
20171 citations
Semantic Scholar
SYNTHETIC STUDIES OF TRICHOTHECENES
P. Grothaus
19831 citations
Semantic Scholar
Abstract 2025: Phosphoproteomic profiling following MAP3K1 kinase inhibition identifies NPM1 as a novel substrate
L. Boghean, Sarbjit Singh, K. Mangalaparthi, S. Shukla +9 more
2023Cancer Research0 citations
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ANTI-PROLIFERATIVE EFFECTS OF STREPTOCOCCUS SP. JB24 AND CLADOSPORIUM SP. JF9 METABOLITES ON HELA AND HEPG2 CELLS
Nadumane Vk, V. Nadumane, F. John, C. Kerr +57 more
2022International Journal of Biology Pharmacy and Allied Sciences0 citations Open access
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Front Cover: A New Bispyrroloiminoquinone Alkaloid From a Thai Collection of Clavelina sp. (Asian J. Org. Chem. 7/2021)
Tanja Grkovic, S. Ruchirawat, P. Kittakoop, P. Grothaus +5 more
2021Asian Journal of Organic Chemistry0 citations Open access
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Naturally occurring disulfide-rich cyclic peptides from plants and animals: Synthesis and biosynthesis
D. Newman, G. Cragg, P. Grothaus
20170 citations
Semantic Scholar
On the Chemistry and Biology of the Marine Macrolides Zampanolide and Dactylolide
D. Newman, G. Cragg, P. Grothaus
20170 citations
Semantic Scholar
Cone Snail Venom Peptides and Future Biomedical Applications of Natural Products
D. Newman, G. Cragg, P. Grothaus
20170 citations
Semantic Scholar
Deep-Sea Hydrothermal Vent Organisms as Sources of Natural Products
D. Newman, G. Cragg, P. Grothaus
20170 citations
Semantic Scholar
Naturally Occurring Disulfide-Rich Cyclic Peptides from Plants and Animals : Synthesis and Biosynthesis
D. Newman, G. Cragg, P. Grothaus
20170 citations
Semantic Scholar
jY-(4'-Hydroxyphenylacetyl)palytoxin: A Palytoxin Prodrug That Can Be Activated by a Monoclonal Antibody-Penicillin G Amidase Conjugate1
G. Bignami, P. Senter, P. Grothaus, K. Fischer +2 more
20060 citations
Semantic Scholar
Tetrodoxtoxin Immunoassays. Phase 2
P. Grothaus
19910 citations
Semantic Scholar
Asymmetric Microbial Reduction of Prochiral 2,2-Disubstituted Cycloalkanediones.
D. W. Brooks, H. Mazdiyasni, P. Grothaus
19880 citations
Semantic Scholar

D. W. Brooks

×5

Jason R. Evans×4

Tanja Grkovic×4

J. R. Britt×3

B. O'Keefe×3

Carolyn B. Lazo×3

H. Mazdiyasni×3

Samantha B. Simpson×3