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H. Mazdiyasni · SciRah

Researcher profile · Semantic Scholar

H. Mazdiyasni

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H. Mazdiyasni — researcher profile on SciRah

h-index: 19
Works: 42
Citations: 1,923

Most-cited papers

Oral, ultra–long-lasting drug delivery: Application toward malaria elimination goals
Andrew M. Bellinger, M. Jafari, Tyler M. Grant, Shiyi Zhang +19 more
2016Science Translational Medicine235 citations Open access
Semantic Scholar
Novel IKK inhibitors: β-carbolines
Alfredo C Castro, L. C. Dang, F. Soucy, L. Grenier +6 more
2003223 citations Open access
Semantic Scholar
Inhibition of Btk with CC-292 Provides Early Pharmacodynamic Assessment of Activity in Mice and Humans
E. Evans, R. Tester, S. Aslanian, R. Karp +13 more
2013Journal of Pharmacology and Experimental Therapeutics220 citations
Semantic Scholar
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
A. Kirtane, Omar Abouzid, Daniel J. Minahan, Taylor Bensel +21 more
2018Nature Communications182 citations Open access
Semantic Scholar
Triggerable tough hydrogels for gastric resident dosage forms
Jin-Yao Liu, Yan Pang, Shiyi Zhang, Cody Cleveland +11 more
2017Nature Communications145 citations Open access
Semantic Scholar
Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kα.
M. Nacht, Li-Xin Qiao, M. Sheets, T. S. St Martin +11 more
2013Journal of Medicinal Chemistry88 citations Open access
Semantic Scholar
Temperature-responsive biometamaterials for gastrointestinal applications
Sahab Babaee, S. Pajovic, A. Kirtane, Jiu-Yun Shi +9 more
2019Science Translational Medicine75 citations Open access
Semantic Scholar
Adenosine kinase inhibition protects brain against transient focal ischemia in rats.
N. Jiang, E. Kowaluk, Chih-Hung Lee, H. Mazdiyasni +1 more
1997European Journal of Pharmacology75 citations
Semantic Scholar
Asymmetric microbial reduction of prochiral 2,2,-disubstituted cycloalkanediones
D. W. Brooks, H. Mazdiyasni, P. Grothaus
198772 citations
Semantic Scholar
In vivo characterization of hydroxamic acid inhibitors of 5-lipoxygenase.
J. Summers, B. Gunn, H. Mazdiyasni, A. Goetze +5 more
1987Journal of Medicinal Chemistry66 citations Open access
Semantic Scholar
Novel IKK inhibitors: beta-carbolines.
Alfredo C Castro, L. C. Dang, F. Soucy, L. Grenier +6 more
2003Bioorganic & Medicinal Chemistry Letters59 citations
Semantic Scholar
Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
J. Summers, K. H. Kim, H. Mazdiyasni, J. Holms +4 more
1990Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
Orally active hydroxamic acid inhibitors of leukotriene biosynthesis.
J. Summers, B. Gunn, Jonathan G. Martin, H. Mazdiyasni +6 more
1988Journal of Medicinal Chemistry51 citations Open access
Semantic Scholar
Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis.
J. Summers, B. Gunn, J. G. Martín, M. B. Martin +6 more
1988Journal of Medicinal Chemistry51 citations Open access
Semantic Scholar
A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment
Malvika Verma, Karan Vishwanath, Feyisope R. Eweje, N. Roxhed +45 more
2019Science Translational Medicine50 citations Open access
Semantic Scholar
Genotype-targeted local therapy of glioma
Ganesh M. Shankar, A. Kirtane, Julie J. Miller, H. Mazdiyasni +29 more
2018Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Total synthesis of the trichothecene mycotoxin anguidine
D. W. Brooks, P. Grothaus, H. Mazdiyasni
198346 citations
Semantic Scholar
Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase.
T. Jones, S. Webber, M. Varney, M. R. Reddy +19 more
1997Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.
A. Stewart, P. Bhatia, Jonathan G. Martin, James B. Summers +17 more
1997Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
Clinical Development of AVL-292; A Potent, Selective Covalent Btk Inhibitor for the Treatment of B Cell Malignancies,
E. Evans, R. Tester, S. Aslanian, P. Chaturvedi +13 more
201119 citations
Semantic Scholar
Enzyme-catalyzed synthesis of optically pure β-sulfonamidopropionic acids. Useful starting materials for P-3 site modified renin inhibitors
H. Mazdiyasni, D. Konopacki, D. Dickman, T. Zydowsky
199318 citations
Semantic Scholar
Chiral cyclohexanoid synthetic precursors via asymmetricmicrobial reduction of prochiral cyclohexanediones
D. W. Brooks, H. Mazdiyasni, S. Chakrabarti
198418 citations
Semantic Scholar
Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening
Jana R. Jenquin, Alana O’Brien, Kiril K. Poukalov, Yi-Dan Lu +11 more
2022iScience17 citations Open access
Semantic Scholar
Scalable Gastric Resident Systems for Veterinary Application
A. Hayward, Taylor Bensel, H. Mazdiyasni, Jaimie Rogner +11 more
2018Scientific Reports13 citations Open access
Semantic Scholar
Microbial reduction of prochiral 2,2-disubstituted-1,3-cycloheptanediones
D. W. Brooks, H. Mazdiyasni, P. Sallay
198513 citations
Semantic Scholar
Novel IKK Inhibitors: β‐Carbolines.
Alfredo C Castro, L. C. Dang, F. Soucy, L. Grenier +6 more
20035 citations
Semantic Scholar
Practical Synthesis of 2-Pyridone Core: Ethyl 8-Chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizinone-3-carboxylate
Qun Li, T. Sowin, A. Claiborne, Linda Lijewski +10 more
19995 citations Open access
Semantic Scholar
Prolonged Inhibition of BCR Signaling and Suppression of B Cell Lymphoma through Irreversible Inhibition of Bruton’s Tyrosine Kinase
E. Evans, M. Sheets, Hugues Bernard, T. S. St Martin +7 more
20084 citations
Semantic Scholar
CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs
Hannah K. Shorrock, Asmer Aliyeva, Jesus A. Frias, Victoria A. DeMeo +10 more
2024bioRxiv2 citations Open access
Semantic Scholar
Modified Polycyclic Compounds Rescue Mis-splicing in Myotonic Dystrophy Type 1 Disease Models
Jesus A. Frias, S. M. Hicks, H. Mazdiyasni, Subodh K Mishra +19 more
2026ACS Chemical Biology1 citations Open access
Semantic Scholar
A CONVENIENT PREPARATION OF 4-CYCLOPROPYLPHENOL
B. Horrom, H. Mazdiyasni
19921 citations
Semantic Scholar
An ingestible origami-inspired metamaterial for prolonged oral delivery of therapeutics
Farhad Javid, Sahab Babaee, Jasmine Quigley, A. Kirtane +11 more
2026Nature Communications0 citations Open access
Semantic Scholar
Abstract 4482: Discovery of an irreversible PI3Kα-specific Inhibitor
Li-Xin Qiao, M. Nacht, M. Sheets, T. S. St Martin +9 more
20110 citations
Semantic Scholar
A Novel Covalent Inhibitor of Btk Inhibits B Cell Receptor Signaling and Demonstrates Efficacy in Rheumatoid Arthritis Models
E. Evans, R. Karp, R. Tester, M. Sheets +8 more
20100 citations
Semantic Scholar
Enzyme-Catalyzed Synthesis of Optically Pure β- Sulfonamidopropionic Acids. Useful Starting Materials for P-3 Site Modified Renin Inhibitors.
H. Mazdiyasni, D. Konopacki, D. Dickman, T. Zydowsky
20100 citations
Semantic Scholar
Substituted beta-carboline with ikb kinase inhibitory effect
O. Ritzeler, Alfredo C Castro, L. Grenier, F. Soucy +4 more
20010 citations
Semantic Scholar
4-aminopirrolopirimidinas as quinasa inhibitors.
L. Arnold, D. Calderwood, Bo Deng, G. Hirst +6 more
19990 citations
Semantic Scholar
Structure‐Activity Relationships of N‐Hydroxyurea 5‐Lipoxygenase Inhibitors.
A. Stewart, P. Bhatia, Jonathan G. Martin, J. Summers +17 more
19970 citations
Semantic Scholar
A Convenient Preparation of 4‐Cyclopropylphenol.
B. Horrom, H. Mazdiyasni
19930 citations
Semantic Scholar
Asymmetric Microbial Reduction of Prochiral 2,2-Disubstituted Cycloalkanediones.
D. W. Brooks, H. Mazdiyasni, P. Grothaus
19880 citations
Semantic Scholar
CHIRAL CYCLOHEXANOID SYNTHETIC PRECURSORS VIA ASYMMETRIC MICROBIAL REDUCTION OF PROCHIRAL CYCLOHEXANEDIONES
D. W. Brooks, H. Mazdiyasni, S. Chakrabarti
19840 citations
Semantic Scholar
MIT Open Access Articles Triggerable tough hydrogels for gastric resident dosage forms
Jin-Yao Liu, Yan Pang, Shiyi Zhang, Cody Cleveland +11 more
0 citations
Semantic Scholar

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