Researcher profile · Semantic Scholar

G. Bignami

h-index: 14
Works: 23
Citations: 1,222

Most-cited papers

The search for a taxol-producing microorganism among the endophytic fungi of the Pacific yew, Taxus brevifolia.
A. Stierle, G. Strobel, D. Stierle, P. Grothaus +1 more
1995Journal of Natural Products255 citations
Semantic Scholar
Development of a Recombinant Tetravalent Dengue Virus Vaccine: Immunogenicity and Efficacy Studies in Mice and Monkeys
D. Clements, B. Coller, M. M. Lieberman, S. Ogata +11 more
2010Vaccine205 citations Open access
Semantic Scholar
An evaluation of dengue type-2 inactivated, recombinant subunit, and live-attenuated vaccine candidates in the rhesus macaque model.
J. Putnak, B. Coller, G. Voss, D. Vaughn +16 more
2005Vaccine170 citations
Semantic Scholar
A rapid and sensitive hemolysis neutralization assay for palytoxin.
G. Bignami
1993Toxicon158 citations
Semantic Scholar
Stereostructure and biological activity of 42-hydroxy-palytoxin: a new palytoxin analogue from Hawaiian Palythoa subspecies.
P. Ciminiello, C. Dell’Aversano, Emma Dello Iacovo, E. Fattorusso +9 more
2009Chemical Research in Toxicology85 citations
Semantic Scholar
Monoclonal antibody-based enzyme-linked immunoassays for the measurement of palytoxin in biological samples.
G. Bignami, T. J. Raybould, N. Sachinvala, P. Grothaus +5 more
1992Toxicon58 citations
Semantic Scholar
A monoclonal antibody‐based immunoassay for detecting tetrodotoxin in biological samples
T. J. Raybould, G. Bignami, L. Inouye, Samantha B. Simpson +3 more
1992Journal of clinical laboratory analysis (Print)50 citations
Semantic Scholar
Acute oral toxicity in mice of a new palytoxin analog: 42-hydroxy-palytoxin.
A. Tubaro, G. del Favero, D. Beltramo, M. Ardizzone +7 more
2011Toxicon41 citations
Semantic Scholar
Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and "total taxanes" in Taxus brevifolia extracts by enzyme immunoassay.
P. Grothaus, G. Bignami, S. O'Malley, Kent E. Harada +5 more
1995Journal of Natural Products36 citations
Semantic Scholar
Lophozozymus pictor toxin: a fluorescent structural isomer of palytoxin.
C.-W.-Z. Lau, C. H. Tan, H. Khoo, R. Yuen +3 more
1995Toxicon28 citations
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Stereoisomers of 42-hydroxy palytoxin from Hawaiian Palythoa toxica and P. tuberculosa: stereostructure elucidation, detection, and biological activities.
P. Ciminiello, C. Dell’Aversano, Emma Dello Iacovo, M. Forino +7 more
2014Journal of Natural Products27 citations
Semantic Scholar
Phase II clinical and pharmacological study of didemnin B in patients with metastatic breast cancer
J. Benvenuto, Robert A. Newman, G. Bignami, T. J. Raybould +3 more
1992Investigational new drugs27 citations
Semantic Scholar
Bioactive metabolites of the endophytic fungi of Pacific yew, Taxus brevifolia: paclitaxel, taxanes, and other bioactive compounds
A. Stierle, D. Stierle, G. Strobel, G. Bignami +1 more
199519 citations
Semantic Scholar
Comparative in vitro cytotoxicity of cyclophosphamide, its major active metabolites and the new oxazaphosphorine ASTA Z 7557 (INN mafosfamide)
D. Alberts, J. Einspahr, R. Struck, G. Bignami +3 more
2004Investigational new drugs18 citations
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Biological activity of 26-succinylbryostatin 1.
G. Bignami, F. Wagner, P. Grothaus, P. Rustagi +2 more
1996Biochimica et Biophysica Acta12 citations Open access
Semantic Scholar
Analysis of spatial variability in hyperspectral imagery of the uterine cervix in vivo
M. DeWeert, J. Oyama, E. McLaughlin, E. Jacobson +14 more
2003SPIE BiOS9 citations Open access
Semantic Scholar
Evidence for palytoxin as one of the sheep erythrocyte lytic in lytic factors in crude extracts of ciguateric and non-ciguateric reef fish tissue.
K. Wachi, Y. Hokama, L. Haga, A. Shiraki +3 more
2000Journal of natural toxins8 citations
Semantic Scholar
Antibodies to maitotoxin elicited by immunization with toxin-fragment conjugates.
G. Bignami, David F. Waller, T. Yasumoto
1996Toxicon6 citations
Semantic Scholar
Endophytic Fungi of Pacific Yew (Taxus brevifolia) as a Source of Taxol, Taxanes, and Other Pharmacophores
A. Stierle, D. Stierle, G. Stobel, G. Bignami +1 more
19945 citations
Semantic Scholar
An enzyme immunoassay for determining plasma concentrations of didemnin B
T. J. Raybould, P. Grothaus, Samantha B. Simpson, G. Bignami +2 more
1992Journal of clinical laboratory analysis (Print)5 citations
Semantic Scholar
Toxicity of palytoxin and 42-hydroxy-palytoxin on cultured mouse skeletal muscle cells
G. del Favero, P. Lorenzon, C. Florio, S. Sosa +5 more
20100 citations
Semantic Scholar
jY-(4'-Hydroxyphenylacetyl)palytoxin: A Palytoxin Prodrug That Can Be Activated by a Monoclonal Antibody-Penicillin G Amidase Conjugate1
G. Bignami, P. Senter, P. Grothaus, K. Fischer +2 more
20060 citations
Semantic Scholar
BIOACTIVATION OF CYCLOPHOSPHAMIDE FOR USE IN THE HUMAN TUMOR STEM CELL ASSAY.
G. Bignami
19820 citations
Semantic Scholar

M. Poli

×4

D. Stierle×3

T. Humphreys×3

M. Forino×3

Samantha B. Simpson×3

Jilanne B. Byrnes×3

S. Sosa×3

G. Strobel×2