G. Mittapalli

Most-cited papers

1. Mapping the landscape of potentially primordial informational oligomers: oligodipeptides and oligodipeptoids tagged with triazines as recognition elements.

   G. Mittapalli, K. R. Reddy, Hui Xiong, Omar Munoz +4 more

   2007Angewandte Chemie95 citations

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2. Mapping the landscape of potentially primordial informational oligomers: oligodipeptides tagged with 2,4-disubstituted 5-aminopyrimidines as recognition elements.

   G. Mittapalli, Y. M. Osornio, Miguel Guerrero, K. R. Reddy +2 more

   2007Angewandte Chemie83 citations

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3. Tau pathology reduction with SM07883, a novel, potent, and selective oral DYRK1A inhibitor: A potential therapeutic for Alzheimer's disease

   B. Melchior, G. Mittapalli, Carolyn Lai, Karen X. Duong-Polk +10 more

   2019Aging Cell33 citations Open access

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4. Ligands of the Neuropeptide Y Y2 receptor

   G. Mittapalli, E. Roberts

   2013Bioorganic & Medicinal Chemistry Letters27 citations Open access

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5. O4‐05‐03: TAU PATHOLOGY REDUCTION WITH SM07883, A NOVEL, POTENT, AND SELECTIVE ORAL DYRK1A INHIBITOR: A POTENTIAL THERAPEUTIC FOR ALZHEIMER'S DISEASE

   B. Melchior, Carolyn Lai, Karen X. Duong-Polk, A. Tjitro +7 more

   201826 citations

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6. Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor.

   G. Mittapalli, Fang Zhao, Andrew Jackson, Hongfeng Gao +8 more

   2012Bioorganic & Medicinal Chemistry Letters22 citations Open access

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7. Discovery of highly potent small molecule Hepatitis C Virus entry inhibitors.

   G. Mittapalli, Andrew Jackson, Fang Zhao, Haekyung Lee +4 more

   2011Bioorganic & Medicinal Chemistry Letters21 citations Open access

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8. Synthesis and SAR of selective small molecule Neuropeptide Y Y2 receptor antagonists

   G. Mittapalli, Danielle Vellucci, Jun Yang, M. Toussaint +3 more

   2012Bioorganic & Medicinal Chemistry Letters16 citations Open access

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9. Structure activity relationships of novel antiepileptic drugs.

   G. Mittapalli, E. Roberts

   2014Current Medicinal Chemistry14 citations

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10. A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y2R Antagonists

    Kerstin Burkert, Tristan Zellmann, R. Meier, A. Kaiser +5 more

    2017ChemMedChem4 citations

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11. Discovery and Preclinical Development of SM15685, a Novel Highly Selective Oral DYRK1A/B Inhibitor as a Potential Therapeutic for Alzheimer’s Disease

    Chi-Ching Mak, G. Mittapalli, Chelsea L. Nora, Emily Creger +8 more

    2024Alzheimer's & Dementia2 citations

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12. Optimization and characterization of an antagonist for vasopressin 1a (V1a) receptor

    G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more

    20142 citations

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13. Abstract 5019: Next-generation DYRK1A inhibitors as a new therapeutic approach for the treatment of hematological malignancies

    Matthew C. Jarvis, G. Mittapalli, Emily Creger, Chelsea L. Nora +10 more

    2023Cancer Research1 citations

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14. DYRK1A controls CD47 endocytic degradation and leukemia immune surveillance

    Won Jun Kim, Alexander Arnuk, Jeetayu Biswas, Cui-Juan Han +23 more

    2025Blood0 citations

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15. Different Y2 receptor antagonists share the same deep, hydrophobic binding pocket

    Kerstin Burkert, Tristan Zellmann, G. Mittapalli, E. Roberts +1 more

    20160 citations

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16. Figure 3, LC-MS of ML389

    G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more

    20140 citations

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17. Table 3, Physicochemical properties of ML389

    G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more

    20140 citations

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18. Figure 4, Stability of ML389 in PBS buffer (pH 7.4)

    G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more

    20140 citations

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19. Figure 2, 13C NMR of ML389

    G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more

    20140 citations

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20. Figure 1, 1H NMR of ML389

    G. Mittapalli, Lusine Argaryan, Steven J. Brown, S. Saldanha +5 more

    20140 citations

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21. Titelbild: Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements (Angew. Chem. 14/2007)

    G. Mittapalli, K. R. Reddy, Hui Xiong, Omar Munoz +6 more

    20070 citations

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