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V. Magdolen · SciRah

Researcher profile · Semantic Scholar

V. Magdolen

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V. Magdolen — researcher profile on SciRah

h-index: 51
Works: 266
Citations: 8,086

Most-cited papers

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10
T. Jefferson, U. auf dem Keller, C. Bellac, Verena V. Metz +15 more
2012Cellular and Molecular Life Sciences132 citations Open access
Semantic Scholar
Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach.
I. Begčević, D. Brinc, Marshall D. Brown, E. Martínez-Morillo +5 more
2018Journal of Proteomics74 citations
Semantic Scholar
Surface loops of trypsin-like serine proteases as determinants of function
P. Goettig, H. Brandstetter, V. Magdolen
2019Biochimie69 citations Open access
Semantic Scholar
CXCL9 inhibits tumour growth and drives anti-PD-L1 therapy in ovarian cancer
S. Seitz, T. Dreyer, Christoph Stange, K. Steiger +7 more
2022British Journal of Cancer62 citations Open access
Semantic Scholar
A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread.
D. Loessner, S. Rizzi, K. Stok, Tobias Führmann +4 more
2013Biomaterials59 citations Open access
Semantic Scholar
Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells
Bettina Grismayer, Susanne Sölch, Bastian Seubert, T. Kirchner +7 more
2012Molecular Cancer59 citations Open access
Semantic Scholar
Secretome and degradome profiling shows that Kallikrein‐related peptidases 4, 5, 6, and 7 induce TGFβ‐1 signaling in ovarian cancer cells
Hasmik Shahinian, D. Loessner, M. Biniossek, J. Kizhakkedathu +3 more
2013Molecular Oncology58 citations Open access
Semantic Scholar
tRNAGlyGCC-Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression
Konstantina Panoutsopoulou, T. Dreyer, J. Dorn, E. Obermayr +7 more
2021Cancers52 citations Open access
Semantic Scholar
Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer
Tommaso de Marchi, M. Timmermans, A. Sieuwerts, M. Smid +9 more
2017Scientific Reports50 citations Open access
Semantic Scholar
STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization*
M. Didiasova, Dariusz Zakrzewicz, V. Magdolen, C. Nagaraj +4 more
2015Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Emerging clinical importance of the cancer biomarkers kallikrein-related peptidases (KLK) in female and male reproductive organ malignancies
M. Schmitt, V. Magdolen, Feng Yang, M. Kiechle +5 more
2013Radiology and Oncology45 citations Open access
Semantic Scholar
Downregulation of Serine Protease HTRA1 Is Associated with Poor Survival in Breast Cancer
Anna Lehner, V. Magdolen, T. Schuster, M. Kotzsch +5 more
2013PLoS ONE43 citations Open access
Semantic Scholar
Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer
F. Walker, Pascal Nicole, Abdelhak Jallane, A. Soosaipillai +5 more
2014Biological chemistry42 citations
Semantic Scholar
Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors
H. Bronger, V. Magdolen, P. Goettig, T. Dreyer
2019Cancer Metastasis Review39 citations Open access
Semantic Scholar
Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer
Ping Wang, V. Magdolen, C. Seidl, J. Dorn +8 more
2018British Journal of Cancer37 citations Open access
Semantic Scholar
Clinical relevance of kallikrein-related peptidase 6 (KLK6) and 8 (KLK8) mRNA expression in advanced serous ovarian cancer
Nancy C. Ahmed, J. Dorn, R. Napieralski, E. Drecoll +8 more
2016Biological chemistry33 citations Open access
Semantic Scholar
Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity
Wolfgang Skala, Daniel T. Utzschneider, V. Magdolen, M. Debela +4 more
2014Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer
D. Loessner, P. Goettig, S. Preis, J. Felber +4 more
2018Expert opinion on therapeutic targets32 citations
Semantic Scholar
Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET
O. Goldhardt, Inanna Warnhoff, I. Yakushev, I. Begčević +6 more
2019Translational Neurodegeneration31 citations Open access
Semantic Scholar
Function and clinical relevance of kallikrein-related peptidases and other serine proteases in gynecological cancers
J. Dorn, Nathalie Beaufort, M. Schmitt, E. Diamandis +2 more
2014Critical reviews in clinical laboratory sciences28 citations
Semantic Scholar
Sweetened kallikrein-related peptidases (KLKs): glycan trees as potential regulators of activation and activity
Shi-Hui Guo, Wolfgang Skala, V. Magdolen, H. Brandstetter +1 more
2014Biological chemistry28 citations Open access
Semantic Scholar
Clinical utility of kallikrein-related peptidases (KLK) in urogenital malignancies
J. Dorn, J. Bayani, G. Yousef, Feng Yang +4 more
2013Thrombosis and Haemostasis28 citations
Semantic Scholar
Tissue kallikrein-related peptidase 4 (KLK4), a novel biomarker in triple-negative breast cancer
Feng Yang, M. Aubele, A. Walch, E. Gross +9 more
2017Biological chemistry26 citations
Semantic Scholar
PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients
M. Absmaier, R. Napieralski, T. Schuster, M. Aubele +8 more
2018International Journal of Oncology25 citations Open access
Semantic Scholar
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer
Xiaocong Geng, Yue-Yang Liu, S. Diersch, M. Kotzsch +5 more
2017PLoS ONE25 citations Open access
Semantic Scholar
Peer Review #2 of "Identification of potential biomarkers and pivotal biological pathways for prostate cancer using bioinformatics analysis methods (v0.2)"
Zi-Hao He, Xiao-Lu Duan, Guo-Hua Zeng, Along Gou +404 more
201924 citations Open access
Semantic Scholar
Clinical value of protein expression of kallikrein-related peptidase 7 (KLK7) in ovarian cancer.
J. Dorn, Apostolos Gkazepis, M. Kotzsch, M. Kremer +7 more
2014Biological chemistry24 citations Open access
Semantic Scholar
tRNA-derived small RNA 3'U-tRFValCAC promotes tumour migration and early progression in ovarian cancer.
Konstantina Panoutsopoulou, Paraskevi Magkou, T. Dreyer, J. Dorn +8 more
2022European Journal of Cancer23 citations
Semantic Scholar
Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome*
L. M. Silva, T. Kryza, T. Stoll, C. Hoogland +7 more
2019Molecular & Cellular Proteomics23 citations Open access
Semantic Scholar
The Predictive Value of PITX2 DNA Methylation for High-Risk Breast Cancer Therapy: Current Guidelines, Medical Needs, and Challenges
M. Aubele, M. Schmitt, R. Napieralski, S. Paepke +7 more
2017Disease Markers22 citations Open access
Semantic Scholar
The Chemokine CX3CL1 Improves Trastuzumab Efficacy in HER2 Low–Expressing Cancer In Vitro and In Vivo
T. Dreyer, Sabine Kuhn, Christoph Stange, N. Heithorst +17 more
2021Cancer immunology research21 citations Open access
Semantic Scholar
Aberrant expression of kallikrein‐related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion
Tiphaine Delaunay, L. Deschamps, M. Haddada, F. Walker +7 more
2017Molecular Oncology21 citations Open access
Semantic Scholar
A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity
Shi-Hui Guo, Wolfgang Skala, V. Magdolen, P. Briza +5 more
2015Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1
T. Kryza, T. Khan, S. Lovell, Brittney S. Harrington +11 more
2021Nature Chemical Biology20 citations Open access
Semantic Scholar
Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
J. C. Reid, Admire Matsika, Claire M. Davies, Yao-Wu He +6 more
2017American Journal of Cancer Research20 citations
Semantic Scholar
Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma
J. Candido, O. Maiques, M. Boxberg, V. Kast +8 more
2021Cancers18 citations Open access
Semantic Scholar
Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients
W. Gong, Yue-Yang Liu, C. Seidl, T. Dreyer +5 more
2019PLoS ONE18 citations Open access
Semantic Scholar
Herpes simplex virus alters Alzheimer's disease biomarkers ‐ A hypothesis paper
O. Goldhardt, R. Freiberger, T. Dreyer, Luisa Wilner +10 more
2022Alzheimer's & Dementia17 citations Open access
Semantic Scholar
Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors.
O. Pilgram, A. Keils, Gerrit E. Benary, Janis Müller +9 more
2022European journal of medicinal chemistry16 citations Open access
Semantic Scholar
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
Xiaocong Geng, Yue-Yang Liu, T. Dreyer, H. Bronger +3 more
2018American Journal of Cancer Research16 citations
Semantic Scholar
Clinical performance of an analytically validated assay in comparison to microarray technology to assess PITX2 DNA-methylation in breast cancer
Gabriele Schricker, R. Napieralski, A. Noske, E. Piednoir +11 more
2018Scientific Reports16 citations Open access
Semantic Scholar
Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221
N. Falkenberg, Nataša Anastasov, A. Schaub, Vanja Radulovic +3 more
2015OncoTarget16 citations Open access
Semantic Scholar
Association of Tissue mRNA and Serum Antigen Levels of Members of the Urokinase-Type Plasminogen Activator System with Clinical and Prognostic Parameters in Prostate Cancer
O. Al-Janabi, H. Taubert, A. Lohse-Fischer, M. Fröhner +12 more
2014BioMed Research International16 citations Open access
Semantic Scholar
Prognostic value of kallikrein-related peptidase 7 (KLK7) mRNA expression in advanced high-grade serous ovarian cancer
W. Gong, Yue-Yang Liu, E. Diamandis, M. Kiechle +4 more
2020Journal of Ovarian Research15 citations Open access
Semantic Scholar
The prognostic and diagnostic potential of kallikrein-related peptidases in ovarian cancer
M. Riedel, H. Bronger, V. Magdolen, T. Dreyer
2021Expert Review of Molecular Diagnostics14 citations
Semantic Scholar
Kallikrein-related peptidase 7 overexpression in melanoma cells modulates cell adhesion leading to a malignant phenotype
M. Haddada, Hend Draoui, L. Deschamps, F. Walker +4 more
2018Biological chemistry14 citations
Semantic Scholar
Plasmin(ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer
Shuo Zhao, J. Dorn, R. Napieralski, A. Walch +7 more
2017Biological chemistry14 citations
Semantic Scholar
Inverse association of rab31 and mucin-1 (CA15-3) antigen levels in estrogen receptor-positive (ER+) breast cancer tissues with clinicopathological parameters and patients' prognosis.
M. Kotzsch, T. Kirchner, Susanne Soelch, Sonja Schäfer +4 more
2017American Journal of Cancer Research14 citations
Semantic Scholar
Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin
M. Debela, V. Magdolen, Wolfgang Skala, Brigitta Elsässer +7 more
2018Scientific Reports13 citations Open access
Semantic Scholar
Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10
M. Debela, V. Magdolen, W. Bode, H. Brandstetter +1 more
2016Biological chemistry13 citations Open access
Semantic Scholar

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