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M. Biniossek · SciRah

Researcher profile · Semantic Scholar

M. Biniossek

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M. Biniossek — researcher profile on SciRah

h-index: 30
Works: 99
Citations: 2,901

Most-cited papers

The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.
U. Schulte, J. Thumfart, N. Klöcker, C. Sailer +9 more
2006Neuron317 citations Open access
Semantic Scholar
Proteomic identification of protease cleavage sites characterizes prime and non-prime specificity of cysteine cathepsins B, L, and S.
M. Biniossek, D. K. Nägler, Christoph Becker-Pauly, O. Schilling
2011Journal of Proteome Research175 citations
Semantic Scholar
Fibroblast activation protein‐α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations
M. Koczorowska, S. Tholen, F. Bucher, L. Lutz +7 more
2016Molecular Oncology111 citations Open access
Semantic Scholar
Structural characterization of fish egg vitelline envelope proteins by mass spectrometry.
Costel C. Darie, M. Biniossek, L. Jovine, E. Litscher +1 more
2004Biochemistry96 citations
Semantic Scholar
Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling.
Tristan Rupp, Benoît Langlois, M. Koczorowska, A. Radwanska +13 more
2016Cell Reports90 citations Open access
Semantic Scholar
Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice
I. Petermann, C. Mayer, J. Stypmann, M. Biniossek +7 more
2006The FASEB Journal76 citations
Semantic Scholar
Isolation and structural characterization of the Ndh complex from mesophyll and bundle sheath chloroplasts of Zea mays
Costel C. Darie, M. Biniossek, Veronika Winter, B. Mutschler +1 more
2005The FEBS Journal70 citations Open access
Semantic Scholar
TIP47 plays a crucial role in the life cycle of hepatitis C virus.
Daniela Ploen, M. Hafirassou, Kiyoshi Himmelsbach, D. Sauter +5 more
2013Journal of Hepatology69 citations
Semantic Scholar
Extending the Dynamic Range of Label-free Mass Spectrometric Quantification of Affinity Purifications*
W. Bildl, Alexander Haupt, C. Müller, M. Biniossek +4 more
2011Molecular & Cellular Proteomics66 citations Open access
Semantic Scholar
In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.
Claudia Ryppa, Hagit Mann-Steinberg, I. Fichtner, H. Weber +3 more
2008Bioconjugate chemistry66 citations
Semantic Scholar
Mass Spectrometric Evidence That Proteolytic Processing of Rainbow Trout Egg Vitelline Envelope Proteins Takes Place on the Egg*
Costel C. Darie, M. Biniossek, M. Gawinowicz, Y. Milgrom +4 more
2005Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Secretome and degradome profiling shows that Kallikrein‐related peptidases 4, 5, 6, and 7 induce TGFβ‐1 signaling in ovarian cancer cells
Hasmik Shahinian, D. Loessner, M. Biniossek, J. Kizhakkedathu +3 more
2013Molecular Oncology58 citations Open access
Semantic Scholar
Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics*
H. Zhang, Elizabeth J. Hamson, M. Koczorowska, S. Tholen +12 more
2018Molecular & Cellular Proteomics56 citations Open access
Semantic Scholar
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
F. Dong, Michael Eibach, J. Bartsch, A. Dolga +10 more
2015Neuro-Oncology56 citations Open access
Semantic Scholar
The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance.
Dönem Avci, Shai Fuchs, Bianca Schrul, Akio Fukumori +9 more
2014Molecules and Cells56 citations Open access
Semantic Scholar
Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin
F. Haun, Simon Neumann, L. Peintner, K. Wieland +13 more
2018Nature Communications54 citations Open access
Semantic Scholar
Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization
M. Föll, M. Fahrner, V. Oria, Markus Kühs +4 more
2018Clinical Proteomics51 citations Open access
Semantic Scholar
TIP47 is associated with the hepatitis C virus and its interaction with Rab9 is required for release of viral particles.
Daniela Ploen, M. Hafirassou, Kiyoshi Himmelsbach, Stefan A Schille +4 more
2013European Journal of Cell Biology49 citations
Semantic Scholar
Identification of tissue damage, extracellular matrix remodeling and bacterial challenge as common mechanisms associated with high-risk cutaneous squamous cell carcinomas.
M. Föll, M. Fahrner, C. Gretzmeier, K. Thoma +6 more
2017Matrix Biology47 citations
Semantic Scholar
Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics*
M. Biniossek, M. Niemer, Kenneth R. Maksimchuk, Bettina Mayer +9 more
2016Molecular & Cellular Proteomics46 citations Open access
Semantic Scholar
Septins Arrange F-Actin-Containing Fibers on the Chlamydia trachomatis Inclusion and Are Required for Normal Release of the Inclusion by Extrusion
Larisa Volceanov, Katharina Herbst, M. Biniossek, O. Schilling +6 more
2014mBio46 citations Open access
Semantic Scholar
Deletion of Cysteine Cathepsins B or L Yields Differential Impacts on Murine Skin Proteome and Degradome*
S. Tholen, M. Biniossek, Martina Gansz, Alejandro Gomez-Auli +7 more
2012Molecular & Cellular Proteomics46 citations Open access
Semantic Scholar
In vitro and in vivo evaluation of a paclitaxel conjugate with the divalent peptide E-[c(RGDfK)2] that targets integrin alpha v beta 3.
Claudia Ryppa, Hagit Mann-Steinberg, M. Biniossek, R. Satchi-Fainaro +1 more
2009International journal of pharmaceutics45 citations
Semantic Scholar
Development of protein-binding bifunctional linkers for a new generation of dual-acting prodrugs.
Khalid Abu Ajaj, M. Biniossek, F. Kratz
2009Bioconjugate chemistry44 citations
Semantic Scholar
Impact of routinely employed procedures for tissue processing on the proteomic analysis of formalin‐fixed paraffin‐embedded tissue
P. Bronsert, J. Weißer, M. Biniossek, M. Kuehs +9 more
2014PROTEOMICS - Clinical Applications39 citations
Semantic Scholar
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis
S. Tholen, M. Biniossek, Martina Gansz, Theresa D. Ahrens +4 more
2014Cellular and Molecular Life Sciences37 citations Open access
Semantic Scholar
Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells
U. Kern, Vladimir Wischnewski, M. Biniossek, O. Schilling +1 more
2015Molecular Cancer36 citations Open access
Semantic Scholar
Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications.
Adrian Sprenger, Victoria Küttner, M. Biniossek, C. Gretzmeier +5 more
2010Molecular Biosystems36 citations
Semantic Scholar
Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts
S. Tholen, M. Biniossek, Anna-Lena Geßler, Sebastian Müller +4 more
2011Biological chemistry32 citations Open access
Semantic Scholar
The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia.
J. D. Knopf, S. Tholen, M. Koczorowska, O. De Wever +2 more
2015Biochimica et Biophysica Acta30 citations Open access
Semantic Scholar
miR-200c dampens cancer cell migration via regulation of protein kinase a subunits
F. Sigloch, U. Burk, M. Biniossek, T. Brabletz +1 more
2015OncoTarget29 citations Open access
Semantic Scholar
Enrichment of protein N‐termini by charge reversal of internal peptides
Z. W. Lai, Alejandro Gomez-Auli, Eva J. Keller, Bettina Mayer +2 more
2015Proteomics29 citations
Semantic Scholar
SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.
M. Rogg, Jasmin I. Maier, R. Dotzauer, Nadine Artelt +16 more
2021Journal of the American Society of Nephrology28 citations Open access
Semantic Scholar
Proteome Profiling of Primary Pancreatic Ductal Adenocarcinomas Undergoing Additive Chemoradiation Link ALDH1A1 to Early Local Recurrence and Chemoradiation Resistance
V. Oria, P. Bronsert, A. Thomsen, M. Föll +12 more
2018Translational Oncology27 citations Open access
Semantic Scholar
Neuronal-specific microexon splicing of TAF1 mRNA is directly regulated by SRRM4/nSR100
Simona Capponi, Nadja Stöffler, M. Irimia, F. M. V. Van Schaik +12 more
2019RNA Biology25 citations Open access
Semantic Scholar
Comprehensive Proteomic Analysis of Nitrogen-Starved Mycobacterium smegmatis Δpup Reveals the Impact of Pupylation on Nitrogen Stress Response.
Giuseppina Fascellaro, Agnese Petrera, Z. W. Lai, Paolo Nanni +6 more
2016Journal of Proteome Research25 citations Open access
Semantic Scholar
The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton
M. Rogg, M. Yasuda-Yamahara, A. Abed, P. Dinse +10 more
2017Scientific Reports24 citations Open access
Semantic Scholar
Proteomic Characterization of Prostate Cancer to Distinguish Nonmetastasizing and Metastasizing Primary Tumors and Lymph Node Metastases
Ann-Kathrin Müller, M. Föll, B. Heckelmann, S. Kiefer +5 more
2017Neoplasia24 citations Open access
Semantic Scholar
The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B.
Melanie Paireder, S. Tholen, Andreas Porodko, M. Biniossek +4 more
2017Biochimica et Biophysica Acta - Proteins and Proteomics24 citations Open access
Semantic Scholar
The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity.
Melanie Paireder, Ulrich Mehofer, S. Tholen, Andreas Porodko +8 more
2016Archives of Biochemistry and Biophysics23 citations Open access
Semantic Scholar
Acetylation of Human TCF4 (TCF7L2) Proteins Attenuates Inhibition by the HBP1 Repressor and Induces a Conformational Change in the TCF4::DNA Complex
Susanne Elfert, A. Weise, Katja Bruser, M. Biniossek +3 more
2013PLoS ONE23 citations Open access
Semantic Scholar
Specificity profiling of human trypsin-isoenzymes
O. Schilling, M. Biniossek, Bettina Mayer, Brigitta Elsässer +4 more
2018Biological chemistry22 citations
Semantic Scholar
Impact of cathepsin B on the interstitial fluid proteome of murine breast cancers.
Alejandro Gomez-Auli, L. E. Hillebrand, M. Biniossek, C. Peters +2 more
2016Biochimie22 citations
Semantic Scholar
Quantitative proteomic analysis of formalin–fixed, paraffin–embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines
J. Weißer, Z. W. Lai, P. Bronsert, M. Kuehs +9 more
2015BMC Genomics22 citations Open access
Semantic Scholar
Structural basis for safe and efficient energy conversion in a respiratory supercomplex
Wei-Chun Kao, Claire Ortmann de Percin Northumberland, Tat-Cheung Cheng, J. Ortiz +6 more
2022Nature Communications21 citations Open access
Semantic Scholar
A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity
Shi-Hui Guo, Wolfgang Skala, V. Magdolen, P. Briza +5 more
2015Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Enhanced identification of peptides lacking basic residues by LC‐ESI‐MS/MS analysis of singly charged peptides
M. Biniossek, O. Schilling
2012Proteomics21 citations
Semantic Scholar
Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers.
M. Biniossek, A. Lechel, K. Rudolph, U. Martens +1 more
2013Journal of Proteomics20 citations
Semantic Scholar
Integrating quantitative proteomics with accurate genome profiling of transcription factors by greenCUT&RUN
Sheikh Nizamuddin, Stefanie Koidl, Tanja Bhuiyan, T. Werner +4 more
2021Nucleic Acids Research19 citations Open access
Semantic Scholar
The two cathepsin B-like proteases of Arabidopsis thaliana are closely related enzymes with discrete endopeptidase and carboxydipeptidase activities
Andreas Porodko, Ana Cirnski, Dražen Petrov, T. Raab +10 more
2018Biological chemistry19 citations Open access
Semantic Scholar

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