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S. Budhu · SciRah

Researcher profile · Semantic Scholar

S. Budhu

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S. Budhu — researcher profile on SciRah

h-index: 29
Works: 132
Citations: 6,392

Most-cited papers

Overcoming Resistance to Checkpoint Blockade Therapy by Targeting PI3K-γ in Myeloid Cells
O. de Henau, M. Rausch, D. Winkler, L. Campesato +20 more
2016Nature816 citations Open access
Semantic Scholar
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine
L. Campesato, S. Budhu, J. Tchaicha, Chien-Huan Weng +14 more
2020Nature Communications472 citations Open access
Semantic Scholar
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Katherine B. Chiappinelli, P. Strissel, A. Desrichard, Hui-Li Li +17 more
2017Cell461 citations Open access
Semantic Scholar
T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
Daniel Hirschhorn, S. Budhu, L. Kraehenbuehl, M. Gigoux +30 more
2023Cell272 citations Open access
Semantic Scholar
Rational design of anti-GITR-based combination immunotherapy
R. Zappasodi, C. Sirard, Yan-Yun Li, S. Budhu +15 more
2019Nature Medicine204 citations Open access
Semantic Scholar
Tim-4+ Cavity-Resident Macrophages Impair Anti-Tumor CD8+ T cell Immunity
A. Chow, S. Schad, Michael D. Green, M. Hellmann +37 more
2021Cancer Cell169 citations Open access
Semantic Scholar
Non-conventional inhibitory CD4+Foxp3−PD-1hi T cells as a biomarker of immune checkpoint blockade activity
R. Zappasodi, S. Budhu, M. Hellmann, M. Postow +12 more
2018Cancer Cell144 citations Open access
Semantic Scholar
Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment
S. Budhu, David A. Schaer, Yongbiao Li, R. Toledo-Crow +7 more
2017Science Signaling129 citations Open access
Semantic Scholar
AN ANTI-TUMOR IMMUNE RESPONSE IS EVOKED BY PARTIAL-VOLUME SINGLE DOSE RADIATION IN TWO MURINE MODELS
Ela Markovsky, S. Budhu, R. Samstein, Hongyan Li +11 more
2018International Journal of Radiation Oncology, Biology, Physics89 citations Open access
Semantic Scholar
Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models
Svena Verma, S. Budhu, Inna Serganova, Lauren Dong +9 more
2024Journal of Clinical Investigation85 citations Open access
Semantic Scholar
Systemic antitumor immunity by PD-1/PD-L1 inhibition is potentiated by vascular-targeted photodynamic therapy of primary tumors
M. O'Shaughnessy, K. Murray, Stephen P. La Rosa, S. Budhu +7 more
2017Clinical Cancer Research77 citations Open access
Semantic Scholar
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions
S. Schad, A. Chow, Levi M. B. Mangarin, H. Pan +22 more
2022Journal of Experimental Medicine49 citations Open access
Semantic Scholar
Cytokine release syndrome after radiation therapy: case report and review of the literature
C. Barker, Samuel K. Kim, S. Budhu, K. Matsoukas +2 more
2018Journal of Immunotherapy for Cancer46 citations Open access
Semantic Scholar
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma
S. Budhu, Rachel A Giese, Aditi Gupta, K. Fitzgerald +12 more
2019Cell Reports45 citations Open access
Semantic Scholar
In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors.
D. Khalil, N. Suek, L. Campesato, S. Budhu +17 more
2019Journal of Clinical Investigation38 citations Open access
Semantic Scholar
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade
Arnab Ghosh, J. Michels, Riccardo Mezzadra, D. Venkatesh +23 more
2022Journal of Clinical Investigation24 citations Open access
Semantic Scholar
Apoptotic contraction drives target cell release by cytotoxic T cells
Elisa E. Sanchez, María Tello-Lafoz, Aixuan J. Guo, Miguel M. de Jesus +11 more
2022bioRxiv22 citations Open access
Semantic Scholar
Thrombospondin-1:CD47 signaling contributes to the development of T cell exhaustion in cancer
Chien-Huan Weng, Anais Assouvie, Lauren Dong, Jean-Christophe Beltra +20 more
2025Nature Immunology20 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
ACTIVATION OF STING IN RESPONSE TO PARTIAL-TUMOR RADIATION EXPOSURE
M. Mathieu, S. Budhu, P. R. Nepali, James Russell +4 more
2023International Journal of Radiation Oncology, Biology, Physics17 citations
Semantic Scholar
Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
R. Zappasodi, S. Budhu, M. Hellmann, M. Postow +12 more
2018Cancer Cell17 citations Open access
Semantic Scholar
In vitro assays for effector T cell functions and activity of immunomodulatory antibodies
R. Zappasodi, S. Budhu, Mohsen Abu-Akeel, T. Merghoub
2019Methods in Enzymology16 citations Open access
Semantic Scholar
Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer
Aditi Gupta, S. Budhu, K. Fitzgerald, Rachel A Giese +8 more
2019Communications Biology14 citations Open access
Semantic Scholar
Molecular Heterogeneity and Immune Infiltration Drive Clinical Outcomes in Upper Tract Urothelial Carcinoma
Kwanghee Kim, S. Alam, F. Kuo, Zi-Yu Chen +35 more
2024European Urology13 citations Open access
Semantic Scholar
Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib
Paul B. Chapman, M. Klang, M. Postow, A. Shoushtari +8 more
2023Cancer Research Communications10 citations Open access
Semantic Scholar
Preoperative checkpoint inhibition (CPI) and cryoablation (Cryo) in women with early-stage breast cancer (ESBC).
E. Comen, Yolanda Bryce, D. Page, S. Solomon +16 more
2019Journal of Clinical Oncology9 citations
Semantic Scholar
Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer
E. Comen, S. Budhu, Y. Elhanati, D. Page +12 more
2024iScience8 citations Open access
Semantic Scholar
Cytotoxic T Lymphocytes Control Growth of B16 Tumor Cells in Collagen–Fibrin Gels by Cytolytic and Non-Lytic Mechanisms
B. Majumder, S. Budhu, V. Ganusov
2023Viruses7 citations Open access
Semantic Scholar
Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer
B. Rosenzweig, R. Corradi, S. Budhu, Ricardo G. Alvim +7 more
2021Scientific Reports7 citations Open access
Semantic Scholar
One checkpoint may hide another: inhibiting the TGFβ signaling pathway enhances immune checkpoint blockade.
Aditi Gupta, S. Budhu, T. Merghoub
2019Hepatobiliary surgery and nutrition7 citations Open access
Semantic Scholar
Abstract 4716: Targeting specific TGF-β isoforms in combination with radiation therapy leads to differential antitumor effects in mouse models of cancer
Aditi Gupta, S. Budhu, Rachel A Giese, J. Van Snick +4 more
2018Immunology7 citations
Semantic Scholar
Intermittent MEK inhibition with GITR co-stimulation rescues T-cell function for increased efficacy with CTLA-4 blockade in solid tumor models
Lauren Dong, Hyejin Choi, S. Budhu, Isabell Schulze +10 more
2024Cancer immunology research6 citations Open access
Semantic Scholar
APR-246 increases tumor antigenicity independent of p53
Judith Michels, D. Venkatesh, Cai-Lian Liu, S. Budhu +12 more
2023Life Science Alliance6 citations Open access
Semantic Scholar
A delicate interplay between adaptive and innate immunity caused by immunotherapy triggers tumor immunity and aseptic inflammation
Daniel Hirschhorn, J. Ricca, Billel Gasmi, O. DeHanau +14 more
2018Journal of Immunology5 citations
Semantic Scholar
Activation of Sting in Response to Partial-Tumor Radiation Exposure.
M. Mathieu, P. R. Nepali, S. Budhu, S. Powell +3 more
2021International Journal of Radiation Oncology, Biology, Physics4 citations
Semantic Scholar
Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness
Daniel Hirschhorn, Allison Betof Warner, R. Maniyar, A. Chow +10 more
2021JCI Insight4 citations Open access
Semantic Scholar
Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical models
Arnab Ghosh, J. Michel, Lauren Dong, N. Suek +5 more
2019Experimental and Molecular Therapeutics4 citations
Semantic Scholar
Abstract 250: Activating canonical p53 functions in tumor-associated macrophages improves immune checkpoint blockade efficacy
Arnab Ghosh, J. Michel, D. Venkatesh, Riccardo Mezzadra +18 more
2022Cancer Research2 citations
Semantic Scholar
T Cell Immunotherapies Trigger Neutrophil Activation to Eliminate Tumor Antigen Escape Variants
D. Hirschhorn-Cymerman, J. Ricca, Billel Gasmi, O. de Henau +18 more
20202 citations
Semantic Scholar
Interaction between Kynurenine and the AhR is an effector mechanism of tumor immunosuppression and represents a potential immunotherapy target
L. Campesato, S. Budhu, J. Tchaicha, Stephane Pourpe +5 more
2018Journal of Immunology2 citations
Semantic Scholar
Abstract 574: Phosphatidylserine targeting antibody in combination with tumor radiation and immune checkpoint blockade promotes anti-tumor activity in mouse B16 melanoma
S. Budhu, O. de Henau, R. Zappasodi, Rachel A Giese +6 more
20172 citations
Semantic Scholar
Abstract B056: Thrombospondin-1:CD47 signaling contributes to the development of T cell exhaustion in cancer
Chien-Huan Weng, Anais Assouvie, Lauren Dong, Jean-Christophe Beltra +20 more
2025Cancer immunology research1 citations
Semantic Scholar
Abstract 4053: Targeting oxygen consumption with metformin and phenformin have differential effects on immune cells in the tumor microenvironment
S. Budhu, Anais Assouvie, M. Bah, Svena Verma +7 more
2024Cancer Research1 citations
Semantic Scholar
Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model
S. Budhu, Kwanghee Kim, W. Yip, Stephen P. La Rosa +12 more
2024Frontiers in Oncology1 citations Open access
Semantic Scholar
1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade
Svena Verma, R. Zappasodi, S. Budhu, Inna Serganova +6 more
2023Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
Abstract 2421: WST-11 vascular-targeted photodynamic therapy induced immune modulation in upper tract urothelial cancer
Kwanghee Kim, S. Budhu, W. Yip, A. Tracey +11 more
2023Cancer Research1 citations
Semantic Scholar
Abstract 2890: Investigating dynamic IDO-Kyn-Ahr pathway induced tumor immunosuppression using imaging modality to optimize therapeutic Intervention
M. Bah, I. Serganova, S. Budhu, Tanya Schild +4 more
2023Cancer Research1 citations
Semantic Scholar
Mathematical modeling suggests cytotoxic T lymphocytes control growth of B16 tumor cells in collagin-fibrin gels by cytolytic and non-lytic mechanisms
B. Majumder, S. Budhu, V. Ganusov
2023bioRxiv1 citations Open access
Semantic Scholar
Abstract 1291: APR-246 enhances tumor immunogenicity even in the absence of p53
D. Venkatesh, J. Michels, Cai-Lian Liu, S. Budhu +5 more
2022Cancer Research1 citations
Semantic Scholar
619 Pharmacologic modulation of tumor glycolysis to improve responses to immune checkpoint blockade therapy
Svena Verma, R. Maniyar, M. Ko, S. Budhu +6 more
2021Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar

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