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A. Chow · SciRah

Researcher profile · Semantic Scholar

A. Chow

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A. Chow — researcher profile on SciRah

h-index: 25
Works: 59
Citations: 4,105

Most-cited papers

Clinical implications of T cell exhaustion for cancer immunotherapy
A. Chow, Karlo Perica, C. Klebanoff, J. Wolchok
2022Nature Reviews Clinical Oncology926 citations Open access
Semantic Scholar
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer
J. Chan, Á. Quintanal-Villalonga, Vianne R. Gao, Yu-Bin Xie +30 more
2021Cancer Cell384 citations Open access
Semantic Scholar
T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
Daniel Hirschhorn, S. Budhu, L. Kraehenbuehl, M. Gigoux +30 more
2023Cell272 citations Open access
Semantic Scholar
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
Sydney X. Lu, Emma J. De Neef, James D. Thomas, Erich Sabio +31 more
2021Cell244 citations Open access
Semantic Scholar
Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation.
W. Cho, A. Chow, Joseph S. Au
2009European Journal of Cancer243 citations
Semantic Scholar
Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
Danish Memon, A. Schoenfeld, D. Ye, G. Fromm +29 more
2021bioRxiv203 citations Open access
Semantic Scholar
Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer
Arvind Ravi, M. Hellmann, Monica B. Arniella, Mark Holton +38 more
2023Nature Genetics171 citations Open access
Semantic Scholar
Tim-4+ Cavity-Resident Macrophages Impair Anti-Tumor CD8+ T cell Immunity
A. Chow, S. Schad, Michael D. Green, M. Hellmann +37 more
2021Cancer Cell169 citations Open access
Semantic Scholar
Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation
Á. Quintanal-Villalonga, H. Taniguchi, Ying-Qian A. Zhan, Maysun M. Hasan +32 more
2020bioRxiv158 citations Open access
Semantic Scholar
Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade
Joy A. Pai, M. Hellmann, J. Sauter, Marissa S. Mattar +29 more
2023Cancer Cell154 citations Open access
Semantic Scholar
MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1
W. Cho, A. Chow, Joseph S. Au
2011RNA Biology143 citations Open access
Semantic Scholar
The Ectonucleotidase CD39 Identifies Tumor-Reactive CD8+ T cells Predictive of Immune Checkpoint Blockade Efficacy in Human Lung Cancer
A. Chow, F. Uddin, Michael Liu, A. Dobrin +37 more
2022Immunity115 citations Open access
Semantic Scholar
WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
H. Taniguchi, Rebecca Caeser, S. Chavan, Ying-Qian A. Zhan +16 more
2022Cell Reports112 citations Open access
Semantic Scholar
Targeting LSD1 rescues MHC class I antigen presentation and overcomes PD-L1 blockade resistance in small cell lung cancer
E. Nguyen, H. Taniguchi, J. Chan, Ying-Qian A. Zhan +14 more
2022Journal of Thoracic Oncology103 citations Open access
Semantic Scholar
Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models
Sai Kiran Sharma, A. Chow, S. Monette, D. Vivier +7 more
2018Cancer Research88 citations Open access
Semantic Scholar
Abstract 1189: MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1
W. Cho, A. Chow, Joseph S. Au
201179 citations
Semantic Scholar
Clinical benefit from immunotherapy in patients with small cell lung cancer is associated with tumor capacity for antigen presentation
C. Rudin, D. Balli, W. Lai, A. Richards +9 more
2023Journal of Thoracic Oncology77 citations Open access
Semantic Scholar
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation
Á. Quintanal-Villalonga, H. Taniguchi, Ying-Qian A. Zhan, Maysun M. Hasan +26 more
2021Journal of Hematology & Oncology75 citations Open access
Semantic Scholar
ATR inhibition activates cancer cell cGAS/STING-interferon signaling and promotes antitumor immunity in small-cell lung cancer
H. Taniguchi, Subhamoy Chakraborty, N. Takahashi, Avisek Banerjee +17 more
2024Science Advances63 citations Open access
Semantic Scholar
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions
S. Schad, A. Chow, Levi M. B. Mangarin, H. Pan +22 more
2022Journal of Experimental Medicine49 citations Open access
Semantic Scholar
Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers
Á. Quintanal-Villalonga, V. Durani, A. Sabet, E. Redin +21 more
2023Science Translational Medicine48 citations Open access
Semantic Scholar
MET exon 14-altered lung cancers and MET inhibitor resistance
R. Guo, M. Offin, A. Brannon, Jason C. Chang +22 more
2020Clinical Cancer Research46 citations Open access
Semantic Scholar
Inhibition of XPO1 sensitizes small cell lung cancer to first- and second-line chemotherapy
Á. Quintanal-Villalonga, H. Taniguchi, Yuan Hao, A. Chow +22 more
2021Cancer Research44 citations Open access
Semantic Scholar
Identification of a novel protein complex containing annexin VI, Fyn, Pyk2, and the p120GAP C2 domain
A. Chow, Alison J. Davis, Debra J. Gawler
2000FEBS Letters42 citations Open access
Semantic Scholar
MET inhibitor resistance in patients with MET exon 14-altered lung cancers.
R. Guo, M. Offin, A. Brannon, A. Chow +16 more
2019Journal of Clinical Oncology32 citations
Semantic Scholar
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade
Arnab Ghosh, J. Michels, Riccardo Mezzadra, D. Venkatesh +23 more
2022Journal of Clinical Investigation24 citations Open access
Semantic Scholar
Synthetic dual costimulation increases the potency of HIT and TCR targeted cell therapies
A. Dobrin, P. Lindenbergh, Yuzhe Shi, Karlo Perica +7 more
2024Nature Cancer20 citations Open access
Semantic Scholar
Protocol to dissociate, process, and analyze the human lung tissue using single-cell RNA-seq
Á. Quintanal-Villalonga, J. Chan, I. Masilionis, Vianne R. Gao +7 more
2022STAR Protocols12 citations Open access
Semantic Scholar
GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information
N. Ceglia, Z. Sethna, Samuel S. Freeman, F. Uhlitz +10 more
2023bioRxiv7 citations Open access
Semantic Scholar
Role of CD38 in anti-tumor immunity of small cell lung cancer
H. Taniguchi, S. Chavan, A. Chow, J. Chan +3 more
2024Frontiers in Immunology6 citations Open access
Semantic Scholar
Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade
Joy A. Pai, A. Chow, J. Sauter, Marissa S. Mattar +22 more
2021bioRxiv6 citations Open access
Semantic Scholar
Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector
N. Ceglia, Z. Sethna, Samuel S. Freeman, F. Uhlitz +10 more
2023Nature Communications5 citations Open access
Semantic Scholar
Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness
Daniel Hirschhorn, Allison Betof Warner, R. Maniyar, A. Chow +10 more
2021JCI Insight4 citations Open access
Semantic Scholar
CD39 Identifies Tumor-Reactive CD8 T cells in Patients With Lung Cancer
A. Chow, F. Uddin, Levi M. B. Mangarin, H. Rizvi +32 more
2022bioRxiv2 citations Open access
Semantic Scholar
Abstract 250: Activating canonical p53 functions in tumor-associated macrophages improves immune checkpoint blockade efficacy
Arnab Ghosh, J. Michel, D. Venkatesh, Riccardo Mezzadra +18 more
2022Cancer Research2 citations
Semantic Scholar
1800O Multi-omic characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation
Á. Quintanal-Villalonga, H. Taniguchi, Y. Zhan, M. Hasan +16 more
2021Annals of Oncology2 citations Open access
Semantic Scholar
Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer
J. Chan, Á. Quintanal-Villalonga, Vianne R. Gao, Yu-Bin Xie +24 more
2020bioRxiv2 citations Open access
Semantic Scholar
Abstract 5742: Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
James D. Thomas, Sydney X. Lu, Emma De Neef, Erich Sabio +31 more
2023Cancer Research1 citations
Semantic Scholar
Abstract 1370: Targeting LSD1 rescues MHC-I antigen presentation in small cell lung cancer
M. Nguyen, H. Taniguchi, A. Chow, Ying-Qian A. Zhan +2 more
2022Cancer Research1 citations
Semantic Scholar
Integrative Analysis of Checkpoint Blockade Response in Advanced Non-Small Cell Lung Cancer
Arvind Ravi, J. Gainor, Monica B. Arniella, Mark Holton +37 more
2022bioRxiv1 citations Open access
Semantic Scholar
TCRi: Information theoretic metrics for single cell RNA and TCR sequencing in cancer
N. Ceglia, Z. Sethna, Y. Elhanati, Bharat Burman +10 more
2022bioRxiv1 citations Open access
Semantic Scholar
Targeting LSD1 rescues MHC class I antigen presentation and promotes immune checkpoint blockade response in small cell lung cancer
E. Nguyen, H. Taniguchi, A. Chow, T. Sen +1 more
2022Journal of Immunology1 citations
Semantic Scholar
Signatures of plasticity and immunosuppression in a single-cell atlas of human small cell lung cancer.
J. Chan, Á. Quintanal-Villalonga, Vianne R. Gao, V. Allaj +15 more
20211 citations
Semantic Scholar
Abstract 3468: Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer
V. Naranbhai, Arvind Ravi, M. Hellmann, Monica B. Arniella +38 more
2023Cancer Research0 citations
Semantic Scholar
34P Targeting LSD1 rescues MHC-I antigen presentation and overcomes resistance to PD-L1 checkpoint blockade in small cell lung cancer
E. Nguyen, H. Taniguchi, J. Chan, T. Sen +2 more
2023ESMO Open0 citations Open access
Semantic Scholar
Leveraging CD39 To Identify Tumor-Reactive CD8 T cells In Human Lung Cancer
A. Chow, F. Uddin, Levi M. B. Mangarin, H. Rizvi +31 more
20220 citations Open access
Semantic Scholar
Abstract 3594: Exportin 1 inhibition as a therapeutic strategy for small cell lung cancer
Á. Quintanal-Villalonga, H. Taniguchi, Yuan Hao, A. Chow +12 more
2022Cancer Research0 citations
Semantic Scholar
915 Targeting LSD1 rescues MHC-I antigen presentation and overcomes resistance to PD-L1 blockade therapy in small cell lung cancer
E. Nguyen, A. Chow, C. Rudin, T. Sen +1 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Clinical characteristics and molecular features of non-small cell lung cancers (NSCLCs) following disease progression on immune checkpoint inhibitors (ICIs).
J. Gainor, Arvind Ravi, M. Awad, Mark Holton +15 more
2022Journal of Clinical Oncology0 citations
Semantic Scholar
997 T cell immunotherapies trigger neutrophils to eliminates heterogenous tumors
S. Budhu, D. Redmond, J. Ricca, Billel Gasmi +26 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar

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