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J. Posey · SciRah

Researcher profile · Semantic Scholar

J. Posey

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J. Posey — researcher profile on SciRah

h-index: 34
Works: 73
Citations: 5,347

Most-cited papers

Lack of a role for iron in the Lyme disease pathogen.
J. Posey, F. Gherardini
2000Science550 citations
Semantic Scholar
Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis
M. Farhat, B. Shapiro, K. Kieser, R. Sultana +26 more
2013Nature Genetics446 citations Open access
Semantic Scholar
Molecular Detection of Mutations Associated with First- and Second-Line Drug Resistance Compared with Conventional Drug Susceptibility Testing of Mycobacterium tuberculosis
P. Campbell, G. Morlock, R. D. Sikes, Tracy L. Dalton +6 more
2011Antimicrobial Agents and Chemotherapy383 citations Open access
Semantic Scholar
A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis
P. Miotto, B. Tessema, E. Tagliani, L. Chindelevitch +31 more
2017European Respiratory Journal347 citations Open access
Semantic Scholar
Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis
M. Zaunbrecher, R. D. Sikes, B. Metchock, T. Shinnick +1 more
2009Proceedings of the National Academy of Sciences of the United States of America331 citations Open access
Semantic Scholar
DNA Sequencing Predicts 1st-Line Tuberculosis Drug Susceptibility Profiles
C. Allix-Béguec, Irena Arandjelović, L. Bi, P. Beckert +87 more
2018New England Journal of Medicine326 citations Open access
Semantic Scholar
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: A genotypic analysis
T. Walker, P. Miotto, C. Köser, P. Fowler +20 more
2022The Lancet Microbe234 citations Open access
Semantic Scholar
Pathogen Genomics in Public Health
G. Armstrong, D. MacCannell, H. Carleton, Elizabeth B. Neuhaus +4 more
2019New England Journal of Medicine227 citations Open access
Semantic Scholar
New Insights into Fluoroquinolone Resistance in Mycobacterium tuberculosis: Functional Genetic Analysis of gyrA and gyrB Mutations
S. Malik, M. Willby, D. Sikes, O. Tsodikov +1 more
2012PLoS ONE174 citations Open access
Semantic Scholar
Bacterioferritin A Modulates Catalase A (KatA) Activity and Resistance to Hydrogen Peroxide in Pseudomonas aeruginosa
J. F. Ma, U. Ochsner, M. Klotz, V. Nanayakkara +6 more
1999Journal of Bacteriology160 citations Open access
Semantic Scholar
Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.
M. Farhat, R. Sultana, O. Iartchouk, Sam Bozeman +16 more
2016American Journal of Respiratory and Critical Care Medicine145 citations Open access
Semantic Scholar
Aminoglycoside Cross-Resistance in Mycobacterium tuberculosis Due to Mutations in the 5′ Untranslated Region of whiB7
A. Reeves, P. Campbell, R. Sultana, S. Malik +4 more
2013Antimicrobial Agents and Chemotherapy136 citations Open access
Semantic Scholar
Borrelia oxidative stress response regulator, BosR: A distinctive Zn-dependent transcriptional activator
Julie A. Boylan, J. Posey, F. Gherardini
2003Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
Characterization of a manganese-dependent regulatory protein, TroR, from Treponema pallidum.
J. Posey, J. Hardham, S. Norris, F. Gherardini
1999Proceedings of the National Academy of Sciences of the United States of America118 citations Open access
Semantic Scholar
Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase
M. Ezewudo, A. Borens, Á. Chiner-Oms, P. Miotto +25 more
2018Scientific Reports110 citations Open access
Semantic Scholar
Tuberculosis Vaccine Development: Progress in Clinical Evaluation
S. B. Sable, J. Posey, T. Scriba
2019Clinical Microbiology Reviews98 citations Open access
Semantic Scholar
Bacillus Calmette-Guérin Vaccination Using a Microneedle Patch
Yasuhiro Hiraishi, Subhadra Nandakumar, Seong-O Choi, J. W. Lee +4 more
2011Vaccine96 citations Open access
Semantic Scholar
Mutations at embB Codon 306 Are an Important Molecular Indicator of Ethambutol Resistance in Mycobacterium tuberculosis
A. Starks, A. Gumusboga, B. Plikaytis, T. Shinnick +1 more
2008Antimicrobial Agents and Chemotherapy92 citations Open access
Semantic Scholar
Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis by Use of Real-Time PCR and High-Resolution Melt Analysis
M. V. Ramirez, Kelley C Cowart, P. Campbell, G. Morlock +3 more
2010Journal of Clinical Microbiology74 citations Open access
Semantic Scholar
Characterization of the Twin-Arginine Translocase Secretion System of Mycobacterium smegmatis
J. Posey, T. Shinnick, F. Quinn
2006Journal of Bacteriology65 citations Open access
Semantic Scholar
Correlation between GyrA Substitutions and Ofloxacin, Levofloxacin, and Moxifloxacin Cross-Resistance in Mycobacterium tuberculosis
M. Willby, R. D. Sikes, S. Malik, B. Metchock +1 more
2015Antimicrobial Agents and Chemotherapy58 citations Open access
Semantic Scholar
Bedaquiline micro-heteroresistance after tuberculosis treatment cessation.
M. de Vos, Serej D. Ley, Kristin B. Wiggins, B. Derendinger +13 more
2019New England Journal of Medicine49 citations Open access
Semantic Scholar
Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors
A. Garzan, M. Willby, H. Ngo, C. Gajadeera +6 more
2017ACS Infectious Diseases41 citations Open access
Semantic Scholar
Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region
B. Weiner, James Gomez, T. Victor, R. Warren +14 more
2012PLoS ONE40 citations Open access
Semantic Scholar
Integration of published information into a resistance-associated mutation database for Mycobacterium tuberculosis.
H. Salamon, K. Yamaguchi, D. Cirillo, P. Miotto +9 more
2015Journal of Infectious Diseases39 citations Open access
Semantic Scholar
Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG
C. Gajadeera, M. Willby, K. Green, P. Shaul +4 more
2014Journal of antibiotics (Tokyo. 1968)39 citations Open access
Semantic Scholar
O-mannosylation of the Mycobacterium tuberculosis Adhesin Apa Is Crucial for T Cell Antigenicity during Infection but Is Expendable for Protection
Subhadra Nandakumar, S. Kannanganat, K. Dobos, Megan Lucas +11 more
2013PLoS Pathogens39 citations Open access
Semantic Scholar
Cellular Immune Responses to Nine Mycobacterium tuberculosis Vaccine Candidates following Intranasal Vaccination
S. B. Sable, Mani Cheruvu, Subhadra Nandakumar, Sunita Sharma +6 more
2011PLoS ONE38 citations Open access
Semantic Scholar
Attrition of T-Cell Functions and Simultaneous Upregulation of Inhibitory Markers Correspond with the Waning of BCG-Induced Protection against Tuberculosis in Mice
Subhadra Nandakumar, S. Kannanganat, J. Posey, R. Amara +1 more
2014PLoS ONE37 citations Open access
Semantic Scholar
Clinical research and development of tuberculosis diagnostics: moving from silos to synergy.
Payam Nahid, P. Kim, C. Evans, D. Alland +20 more
2012Journal of Infectious Diseases37 citations Open access
Semantic Scholar
Validation of Novel Mycobacterium tuberculosis Isoniazid Resistance Mutations Not Detectable by Common Molecular Tests
Justin L Kandler, A. Mercante, Tracy L. Dalton, M. Ezewudo +5 more
2018Antimicrobial Agents and Chemotherapy36 citations Open access
Semantic Scholar
Genomic epidemiology of multidrug-resistant Mycobacterium tuberculosis during transcontinental spread.
Mireia Coscollá, P. Barry, J. Oeltmann, H. Koshinsky +9 more
2015Journal of Infectious Diseases36 citations Open access
Semantic Scholar
Optimizing pyrazinamide for the treatment of tuberculosis
Nan Zhang, R. Savic, M. Boeree, C. Peloquin +12 more
2021European Respiratory Journal34 citations Open access
Semantic Scholar
Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight
K. Green, T. Biswas, A. Pang, M. Willby +6 more
2018Biochemistry34 citations Open access
Semantic Scholar
Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis
A. Garzan, M. Willby, K. Green, C. Gajadeera +4 more
2016Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
Statistical Method to Detect Tuberculosis Outbreaks among Endemic Clusters in a Low-Incidence Setting
S. Althomsons, A. Hill, Alexia V. Harrist, A. France +4 more
2018Emerging Infectious Diseases33 citations Open access
Semantic Scholar
Mycobacterium tuberculosis pncA Polymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT
M. G. Whitfield, R. Warren, E. Streicher, S. Sampson +9 more
2015Journal of Clinical Microbiology33 citations Open access
Semantic Scholar
Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis
M. Willby, K. Green, C. Gajadeera, C. Hou +3 more
2016ACS Chemical Biology32 citations Open access
Semantic Scholar
Disparities in Capreomycin Resistance Levels Associated with the rrs A1401G Mutation in Clinical Isolates of Mycobacterium tuberculosis
A. Reeves, P. Campbell, M. Willby, J. Posey
2014Antimicrobial Agents and Chemotherapy31 citations Open access
Semantic Scholar
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic
M. Klopper, T. Heupink, G. Hill-Cawthorne, E. Streicher +11 more
2020BMC Medicine30 citations Open access
Semantic Scholar
Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment
Sophia B. Timothy C. Alexei Said H. Kanchan Jan-Willem Da Georghiou Rodwell Korobitsyn Abbadi Ajbani Alffena, Sophia B. Georghiou, T. Rodwell, A. Korobitsyn +124 more
2022European Respiratory Journal29 citations Open access
Semantic Scholar
Detection of Apparent Cell-free M. tuberculosis DNA from Plasma
E. Click, W. Murithi, G. Ouma, K. McCarthy +6 more
2018Scientific Reports29 citations Open access
Semantic Scholar
Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis.
A. Garzan, M. Willby, K. Green, O. Tsodikov +2 more
2016ACS Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from Mycobacterium tuberculosis
A. Punetha, H. Ngo, Selina Y. L. Holbrook, K. Green +8 more
2020ACS Chemical Biology24 citations Open access
Semantic Scholar
Potent 1,2,4-Triazino[5,6b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis
H. Ngo, K. Green, C. Gajadeera, M. Willby +7 more
2018ACS Infectious Diseases23 citations Open access
Semantic Scholar
Detection of Mycobacterium tuberculosis pncA Mutations by the Nipro Genoscholar PZA-TB II Assay Compared to Conventional Sequencing
M. Willby, Maria Wijkander, Joshua Havumaki, Kartee Johnson +4 more
2017Antimicrobial Agents and Chemotherapy22 citations Open access
Semantic Scholar
Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission
K. Nelson, Sarah Talarico, Shameer Poonja, Clinton J McDaniel +8 more
2022Frontiers in Public Health20 citations Open access
Semantic Scholar
Ultralong C100 Mycolic Acids Support the Assignment of Segniliparus as a New Bacterial Genus
Sunhee Hong, T. Cheng, É. Layre, L. Sweet +4 more
2012PLoS ONE20 citations Open access
Semantic Scholar
Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis
Subhadra Nandakumar, S. Kannanganat, K. Dobos, Megan Lucas +5 more
2016Scientific Reports19 citations Open access
Semantic Scholar
Using Reduced Inoculum Densities of Mycobacterium tuberculosis in MGIT Pyrazinamide Susceptibility Testing to Prevent False-Resistant Results and Improve Accuracy: A Multicenter Evaluation
G. Morlock, Frances C Tyrrell, D. Baynham, V. Escuyer +8 more
2017Tuberculosis Research and Treatment17 citations Open access
Semantic Scholar

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