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C. Hou · SciRah

Researcher profile · Semantic Scholar

C. Hou

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C. Hou — researcher profile on SciRah

h-index: 18
Works: 80
Citations: 961

Most-cited papers

Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches
R. M. Pinto, E. Dragileva, Andrew W. Kirby, Alejandro Lloret +12 more
2013PLoS Genetics244 citations Open access
Semantic Scholar
Multiple effects of antibiotics on chloroplast and nuclear gene expression.
P. Mulo, Saijaliisa Pursiheimo, C. Hou, T. Tyystjärvi +1 more
2003Functional Plant Biology69 citations
Semantic Scholar
Incision-Dependent and Error-Free Repair of (CAG)n/(CTG)n Hairpins in Human Cell Extracts
C. Hou, N. Chan, L. Gu, Guo-Min Li
2009Nature Structural &Molecular Biology56 citations Open access
Semantic Scholar
Mismatch Recognition Protein MutSβ Does Not Hijack (CAG)n Hairpin Repair in Vitro*
L. Tian, C. Hou, Ke-li Tian, Nathaniel Holcomb +2 more
2009Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors
A. Garzan, M. Willby, H. Ngo, C. Gajadeera +6 more
2017ACS Infectious Diseases41 citations Open access
Semantic Scholar
Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis
A. Garzan, M. Willby, K. Green, C. Gajadeera +4 more
2016Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis
M. Willby, K. Green, C. Gajadeera, C. Hou +3 more
2016ACS Chemical Biology32 citations Open access
Semantic Scholar
Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1
C. Hou, S. Weidenbach, Kristin E. Cano, Zhong-Hua Wang +4 more
2016Nucleic Acids Research30 citations Open access
Semantic Scholar
Improved hybrid optimization algorithm for 3D protein structure prediction
Chang-Jun Zhou, C. Hou, Xiaopeng Wei, Qiang Zhang
2014Journal of Molecular Modeling29 citations
Semantic Scholar
Ascorbate-mediated LHCII protein phosphorylation--LHCII kinase regulation in light and in darkness.
C. Hou, E. Rintamäki, E. Aro
2003Biochemistry29 citations
Semantic Scholar
Plant peptide deformylase: a novel selectable marker and herbicide target based on essential cotranslational chloroplast protein processing.
C. Hou, L. Dirk, S. Pattanaik, N. C. Das +3 more
2007Plant Biotechnology Journal28 citations
Semantic Scholar
The Werner Syndrome Protein Promotes CAG/CTG Repeat Stability by Resolving Large (CAG)n/(CTG)n Hairpins*
N. Chan, C. Hou, Tian-Yi Zhang, F. Yuan +5 more
2012Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Environmental and metabolic control of LHCII protein phosphorylation: revealing the mechanisms for dual regulation of the LHCII kinase
C. Hou, Saijaliisa Pursiheimo, E. Rintamäki, E. Aro
200226 citations Open access
Semantic Scholar
Potent 1,2,4-Triazino[5,6b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis
H. Ngo, K. Green, C. Gajadeera, M. Willby +7 more
2018ACS Infectious Diseases23 citations Open access
Semantic Scholar
The Role of XPG in Processing (CAG)n/(CTG)n DNA Hairpins
C. Hou, Tian-Yi Zhang, L. Tian, Jian Huang +2 more
2011Cell & Bioscience23 citations Open access
Semantic Scholar
Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1.
C. Hou, O. Tsodikov
2015Biochemistry22 citations Open access
Semantic Scholar
Coordinated Processing of 3′ Slipped (CAG)n/(CTG)n Hairpins by DNA Polymerases β and δ Preferentially Induces Repeat Expansions*
N. Chan, Jin-Zhen Guo, Tian-Yi Zhang, Guo-Gen Mao +7 more
2013Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins
C. Hou, Abhisek Mandal, J. Rohr, O. Tsodikov
2020Structure18 citations Open access
Semantic Scholar
Dimerization and DNA recognition rules of mithramycin and its analogues
S. Weidenbach, C. Hou, Jhong-Min Chen, O. Tsodikov +1 more
2015Journal of Inorganic Biochemistry18 citations Open access
Semantic Scholar
Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis
Ryan Wheeler, Xia Yu, C. Hou, Prithiba Mitra +5 more
2019Angewandte Chemie16 citations Open access
Semantic Scholar
Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
C. Hou, T. Biswas, O. Tsodikov
2018Biochemistry15 citations Open access
Semantic Scholar
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis to overcome kanamycin resistance.
A. Punetha, K. Green, A. Garzan, Nishad Thamban Chandrika +9 more
2021RSC Medicinal Chemistry13 citations Open access
Semantic Scholar
Enhanced hybrid search algorithm for protein structure prediction using the 3D-HP lattice model
Chang-Jun Zhou, C. Hou, Qiang Zhang, Xiaopeng Wei
2013Journal of Molecular Modeling13 citations
Semantic Scholar
Inhibition of peptide deformylase in Nicotiana tabacum leads to decreased D1 protein accumulation, ultimately resulting in a reduction of photosystem II complexes.
C. Hou, L. Dirk, M. Williams
2004American-Eurasian journal of botany13 citations
Semantic Scholar
Metabolism of the peptide deformylase inhibitor actinonin in tobacco
C. Hou, L. Dirk, J. Goodman, M. Williams
2006Weed science12 citations
Semantic Scholar
Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis
K. Green, A. Punetha, C. Hou, S. Garneau-Tsodikova +1 more
2019ACS Infectious Diseases9 citations Open access
Semantic Scholar
Certification and uncertainty evaluation of flavonoids certified reference materials
Can Quan, Huanfang Yao, C. Hou
20139 citations Open access
Semantic Scholar
Structural insight into MtmC, a bifunctional ketoreductase-methyltransferase involved in the assembly of the mithramycin trisaccharide chain
Jhong-Min Chen, C. Hou, Guo-Jun Wang, O. Tsodikov +1 more
2015Biochemistry8 citations Open access
Semantic Scholar
How mithramycin stereochemistry dictates its structure and DNA binding function.
C. Hou, J. Rohr, S. Parkin, O. Tsodikov
2019MedChemComm7 citations Open access
Semantic Scholar
Utilizing guanine-coordinated Zn2+ ions to determine DNA crystal structures by single-wavelength anomalous diffraction.
C. Hou, O. Tsodikov
2019Acta Crystallographica Section D: Structural Biology7 citations
Semantic Scholar
Structural insight into the DNA binding function of transcription factor ERF
C. Hou, Claudia McCown, D. Ivanov, O. Tsodikov
2020Biochemistry6 citations Open access
Semantic Scholar
Molecular cloning and sequence analysis of sglt1 and tertiary structure prediction of deduced protein in Cyprinus carpio L.
Guo-Xing Nie, C. Hou, Jun-Li Wang, Jian-Xin Zhang +4 more
20116 citations
Semantic Scholar
Expression of sglt1 gene in Cyprinus carpio and preparation of its polyclonal antibody
Guo-Xing Nie, Bei Wang, Xiao Yan, C. Hou +4 more
20122 citations
Semantic Scholar
Mithplatins: Mithramycin SA-Pt(II) Complex Conjugates for the Treatment of Platinum Resistant Ovarian Cancers
Suhas S. Bhosale, Abhisek Mandal, C. Hou, J. McCorkle +6 more
2022ChemMedChem1 citations Open access
Semantic Scholar
Development of Single‐Stranded DNA Bisintercalating Inhibitors of Primase DnaG as Antibiotics
K. Green, A. Punetha, Nishad Thamban Chandrika, C. Hou +2 more
2021ChemMedChem1 citations
Semantic Scholar
Solubility of alpha-benzene hexachloride in supercritical carbon dioxide
Yong-Yue Sun, Can Quan, Shu-Fen Li, C. Hou +1 more
20091 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT368
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC
C. Hou, J. Rohr, O. Tsodikov
20200 citations
Semantic Scholar
Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with 16-mer DNA CAGAGGATGTGGCTTC
C. Hou, O. Tsodikov
20200 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT358
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT353
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT384
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC
C. Hou, O. Tsodikov
20200 citations
Semantic Scholar
Crystal structure of the DNA binding domain of human transcription factor ERF in the reduced form, in complex with double-stranded DNA ACCGGAAGTG
C. Hou, O. Tsodikov
20200 citations
Semantic Scholar
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with 16-mer DNA CAGAGGATGTGGCTTC
C. Hou, O. Tsodikov
20200 citations
Semantic Scholar
Mithramycin analogues with unique mechanism of action in Ewing sarcoma
Reiya Hayden, A. Mandal, Yang Liu, C. Hou +4 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT1347
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT1358
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT388
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT392
A. Punetha, C. Hou, H. Ngo, S. Garneau-Tsodikova +1 more
20200 citations
Semantic Scholar

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