Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

C. Overk · SciRah

Researcher profile · Semantic Scholar

C. Overk

Share profile

C. Overk — researcher profile on SciRah

h-index: 31
Works: 75
Citations: 4,395

Most-cited papers

The many faces of α-synuclein: from structure and toxicity to therapeutic target
H. Lashuel, C. Overk, A. Oueslati, E. Masliah
2012Nature Reviews Neuroscience1,564 citations Open access
Semantic Scholar
Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability
Martijn C. de Wilde, C. Overk, J. Sijben, E. Masliah
2016Alzheimer's & Dementia250 citations Open access
Semantic Scholar
PATHOGENESIS OF SYNAPTIC DEGENERATION IN ALZHEIMER’S DISEASE AND LEWY BODY DISEASE
C. Overk, E. Masliah
2014Biochemical Pharmacology228 citations Open access
Semantic Scholar
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.
E. Rockenstein, S. Nuber, C. Overk, K. Ubhi +13 more
2014Brain : a journal of neurology228 citations Open access
Semantic Scholar
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
W. Wrasidlo, I. Tsigelny, D. Price, Garima Dutta +20 more
2016Brain : a journal of neurology144 citations Open access
Semantic Scholar
Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense).
C. Overk, P. Yao, Lucas R. Chadwick, D. Nikolić +8 more
2005Journal of Agricultural and Food Chemistry128 citations
Semantic Scholar
Seasonal variation of red clover (Trifolium pratense L., Fabaceae) isoflavones and estrogenic activity.
N. Booth, C. Overk, P. Yao, S. Totura +5 more
2006Journal of Agricultural and Food Chemistry122 citations Open access
Semantic Scholar
Estrogens and congeners from spent hops (Humulus lupulus).
Lucas R. Chadwick, D. Nikolić, Joanna E. Burdette, C. Overk +6 more
2004Journal of Natural Products121 citations Open access
Semantic Scholar
The Chemical and Biologic Profile of a Red Clover (Trifolium pratense L.) Phase II Clinical Extract
N. Booth, C. Overk, P. Yao, Joanna E. Burdette +6 more
2006Journal of Alternative and Complementary Medicine98 citations Open access
Semantic Scholar
Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
M. Iba, Changyoun Kim, Michelle A. Sallin, Somin Kwon +6 more
2020Journal of Neuroinflammation91 citations Open access
Semantic Scholar
In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin.
C. Overk, Jian Guo, Lucas R. Chadwick, D. Lantvit +8 more
2008Chemico-Biological Interactions90 citations Open access
Semantic Scholar
Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy
B. Spencer, Elvira Valera, E. Rockenstein, C. Overk +9 more
2017Acta Neuropathologica Communications84 citations Open access
Semantic Scholar
Pathogenesis of Age-Related HIV Neurodegeneration
M. Mackiewicz, C. Overk, C. Achim, E. Masliah
2019Journal of Neurovirology77 citations Open access
Semantic Scholar
Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy
O. El-Agnaf, C. Overk, E. Rockenstein, M. Mante +8 more
2017Neurobiology of Disease68 citations Open access
Semantic Scholar
Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies
C. Overk, Anna E. Cartier, G. Shaked, E. Rockenstein +6 more
2014Molecular Neurodegeneration68 citations Open access
Semantic Scholar
Pyrrolizidine alkaloids from Heliotropium indicum
J. R. B. Souza, L. Machado, O. Pessoa, R. Braz-Filho +4 more
200548 citations Open access
Semantic Scholar
Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice
C. Overk, P. Lu, Yue-Ting Wang, Jaewoo Choi +3 more
2011Neurobiology of Disease47 citations Open access
Semantic Scholar
Brainstem Alzheimer’s-Like Pathology in the Triple Transgenic Mouse Model of Alzheimer’s Disease
C. Overk, Christy M Kelley, E. Mufson
2009Neurobiology of Disease47 citations Open access
Semantic Scholar
Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies
E. Rockenstein, Gary R. Ostroff, Fusun Dikengil, Florentina Rus +8 more
2017Journal of Neuroscience45 citations Open access
Semantic Scholar
Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model
B. Spencer, P. Desplats, C. Overk, Elvira Valera-Martin +7 more
2016Journal of Neuroscience45 citations Open access
Semantic Scholar
Impact of Increased APP Gene Dose in Down Syndrome and the Dp16 Mouse Model
Mariko Sawa, C. Overk, A. Becker, Dominique Derse +8 more
2021Alzheimer's & Dementia44 citations Open access
Semantic Scholar
Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson’s Disease/Dementia with Lewy Bodies
D. Price, E. Rockenstein, M. Mante, A. Adame +6 more
2016Scientific Reports44 citations Open access
Semantic Scholar
Targeting increased levels of APP in Down syndrome: Posiphen‐mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model
Xu-Qiao Chen, A. Salehi, Matthew L. Pearn, C. Overk +4 more
2020Alzheimer's & Dementia43 citations Open access
Semantic Scholar
Molecular determinants of α–synuclein mutants’ oligomerization and membrane interactions
I. Tsigelny, Y. Sharikov, V. Kouznetsova, J. Greenberg +7 more
2015ACS Chemical Neuroscience43 citations Open access
Semantic Scholar
Cortical M1 Receptor Concentration Increases Without a Concomitant Change in Function in Alzheimer's Disease
C. Overk, C. Felder, Yuan Tu, D. Schober +3 more
2010Journal of Chemical Neuroanatomy38 citations Open access
Semantic Scholar
Structure–Activity Relationships for a Family of Benzothiophene Selective Estrogen Receptor Modulators Including Raloxifene and Arzoxifene
C. Overk, K. Peng, Rezene T. Asghodom, I. Kastrati +5 more
2007ChemMedChem38 citations
Semantic Scholar
Sex steroid levels and AD-like pathology in 3xTgAD mice
C. Overk, Sylvia E. Perez, Chunqi Ma, Matthew D. Taves +2 more
2013Journal of neuroendocrinology37 citations Open access
Semantic Scholar
Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD
M. Iba, Changyoun Kim, Somin Kwon, Marcell P. Szabo +11 more
2023Science Translational Medicine36 citations Open access
Semantic Scholar
Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity
J. Fields, C. Overk, A. Adame, J. Florio +6 more
2016Journal of Neuroinflammation36 citations Open access
Semantic Scholar
Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD
S. Nuber, Danielle Tadros, J. Fields, C. Overk +6 more
2014Acta Neuropathologica34 citations Open access
Semantic Scholar
A Novel Triple Repeat Mutant Tau Transgenic Model That Mimics Aspects of Pick’s Disease and Fronto-Temporal Tauopathies
E. Rockenstein, C. Overk, K. Ubhi, M. Mante +6 more
2015PLoS ONE32 citations Open access
Semantic Scholar
RETRACTED ARTICLE: Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
G. Hassen, L. Kesner, A. Stracher, A. Shulman +6 more
2018Scientific Reports28 citations Open access
Semantic Scholar
Structural diversity of Alzheimer’s disease Aβ dimers and their role in oligomerization and fibril formation
I. Tsigelny, Y. Sharikov, V. Kouznetsova, J. Greenberg +7 more
2014Journal of Alzheimer's Disease28 citations Open access
Semantic Scholar
Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies–like model
M. Mandler, E. Rockenstein, C. Overk, M. Mante +11 more
2019Alzheimer's & Dementia26 citations Open access
Semantic Scholar
Differential calcium alterations in animal models of neurodegenerative disease: reversal by FK506
C. Overk, E. Rockenstein, J. Florio, Qun Cheng +1 more
2015Neuroscience26 citations Open access
Semantic Scholar
Neuroprotective effects of the anti‐cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders
W. Wrasidlo, L. Crews, I. Tsigelny, E. Stocking +8 more
2014British Journal of Pharmacology26 citations Open access
Semantic Scholar
High-content screening and mechanism-based evaluation of estrogenic botanical extracts.
C. Overk, P. Yao, Shao-Nong Chen, Shi-Xin Deng +6 more
2008Combinatorial chemistry & high throughput screening25 citations Open access
Semantic Scholar
Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms
Bolan Yu, Birgit M. Dietz, Tareisha L. Dunlap, I. Kastrati +6 more
2007Molecular Cancer Therapeutics23 citations
Semantic Scholar
“Multiple system atrophy: experimental models and reality”.
C. Overk, E. Rockenstein, Elvira Valera, N. Stefanova +2 more
2017Acta Neuropathologica22 citations Open access
Semantic Scholar
Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.
Xuemei Liu, Fa-Gen Zhang, Hong Liu, Joanna E. Burdette +7 more
2003Chemical Research in Toxicology19 citations
Semantic Scholar
Toward a unified therapeutics approach targeting putative amyloid-β oligomer receptors
C. Overk, E. Masliah
2014Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
Structural Modulation of Oxidative Metabolism in Design of Improved Benzothiophene Selective Estrogen Receptor Modulators
Zhi-Hui Qin, I. Kastrati, Rezene T Ashgodom, D. Lantvit +5 more
2009Drug Metabolism And Disposition17 citations Open access
Semantic Scholar
The anti-cancer drug Sunitinib promotes autophagy and protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration
J. Fields, Jeff Metcalf, C. Overk, A. Adame +6 more
2017Journal of Neurovirology16 citations Open access
Semantic Scholar
Effect of Neocortical and Hippocampal Amyloid Deposition upon Galaninergic and Cholinergic Neurites in AβPPswe/PS1ΔE9 Mice
Christy M Kelley, Sylvia E. Perez, C. Overk, D. Wynick +1 more
2011Journal of Alzheimer's Disease15 citations Open access
Semantic Scholar
Activation of estrogen receptor-mediated gene transcription by the equine estrogen metabolite, 4-methoxyequilenin, in human breast cancer cells.
Min-Sun Chang, K. Peng, I. Kastrati, C. Overk +4 more
2007Endocrinology15 citations Open access
Semantic Scholar
Perspective on the calcium dyshomeostasis hypothesis in the pathogenesis of selective neuronal degeneration in animal models of Alzheimer's disease
C. Overk, E. Masliah
2017Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Nicotine-mediated effects in neuronal and mouse models of synucleinopathy
Mohamed-Bilal Fares, Omar Alijevic, Stéphanie Johne, C. Overk +17 more
2023Frontiers in Neuroscience12 citations Open access
Semantic Scholar
A novel approach for long-term oral drug administration in animal research
C. Overk, J. Borgia, E. Mufson
2010Journal of Neuroscience Methods12 citations Open access
Semantic Scholar
Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau
Andrew Arner, E. Rockenstein, M. Mante, J. Florio +6 more
2018Journal of Alzheimer's Disease8 citations Open access
Semantic Scholar
Purification, structure determination, and antimicrobial activity of neutramycins B-G.
Edmund I. Graziani, C. Overk, G. Carter
2003Journal of Natural Products6 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

E. Masliah×27
Invite
E. Masliah — researcher profile on SciRah
E. Rockenstein×19
Invite
E. Rockenstein — researcher profile on SciRah
A. Adame×13
Invite
A. Adame — researcher profile on SciRah
M. Mante×11
Invite
M. Mante — researcher profile on SciRah

×11

Invite

J. Bolton — researcher profile on SciRah

Invite

B. Spencer — researcher profile on SciRah

Invite

R. Rissman — researcher profile on SciRah

Invite

J. Florio — researcher profile on SciRah

Invite

P. Yao — researcher profile on SciRah

Invite

W. Wrasidlo — researcher profile on SciRah

Invite

G. Pauli — researcher profile on SciRah

N. Farnsworth×6

Invite

N. Farnsworth — researcher profile on SciRah