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David K. Lau · SciRah

Researcher profile · Semantic Scholar

David K. Lau

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David K. Lau — researcher profile on SciRah

h-index: 14
Works: 32
Citations: 504

Most-cited papers

Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2
L. Au, A. Fendler, S. Shepherd, K. Rzeniewicz +29 more
2021Nature Medicine90 citations Open access
Semantic Scholar
Oral versus intravenous fluoropyrimidines for colorectal cancer.
F. Chionh, David K. Lau, Yvonne H. Yeung, T. Price +1 more
2017Cochrane Database of Systematic Reviews51 citations Open access
Semantic Scholar
Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study
David K. Lau, R. Tay, Yvonne H. Yeung, F. Chionh +6 more
2018British Journal of Cancer42 citations Open access
Semantic Scholar
HER2 targeted therapy in colorectal cancer: New horizons.
Ali Abdulnabi Mohamed, David K. Lau, I. Chau
2022Cancer Treatment Reviews36 citations
Semantic Scholar
Targeting FGFR2 Positive Gastroesophageal Cancer: Current and Clinical Developments
A. Gordon, Edwina Johnston, David K. Lau, N. Starling
2022OncoTargets and Therapy32 citations Open access
Semantic Scholar
Broadening the therapeutic horizon of advanced biliary tract cancer through molecular characterisation
A. Athauda, C. Fong, David K. Lau, M. Javle +4 more
2020Cancer Treatment Reviews28 citations Open access
Semantic Scholar
Impact of pharmacogenomic DPYD variant guided dosing on toxicity in patients receiving fluoropyrimidines for gastrointestinal cancers in a high-volume tertiary centre
David K. Lau, C. Fong, F. Arouri, Lillian Cortez +13 more
2023BMC Cancer25 citations Open access
Semantic Scholar
Mechanisms of acquired resistance to fibroblast growth factor receptor targeted therapy
David K. Lau, Laura M. Jenkins, A. Weickhardt
2019Cancer Drug Resistance24 citations Open access
Semantic Scholar
K‐Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines
Yvonne H. Yeung, David K. Lau, F. Chionh, Hoanh Tran +6 more
2017Molecular Oncology22 citations Open access
Semantic Scholar
Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer
David K. Lau, Jack P. Collin, J. Mariadason
2024Biomedicines21 citations Open access
Semantic Scholar
Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets
David K. Lau, D. Mouradov, Wiphawan Wasenang, Ian Y Luk +17 more
2019iScience20 citations Open access
Semantic Scholar
Dual targeting of FGFR3 and ERBB3 enhances the efficacy of FGFR inhibitors in FGFR3 fusion-driven bladder cancer
A. Weickhardt, David K. Lau, M. Hodgson-Garms, Austen Lavis +5 more
2021BMC Cancer18 citations Open access
Semantic Scholar
Rapid Resistance of FGFR-driven Gastric Cancers to Regorafenib and Targeted FGFR Inhibitors can be Overcome by Parallel Inhibition of MEK
David K. Lau, Ian Y Luk, Laura J Jenkins, A. Martin +12 more
2021Molecular Cancer Therapeutics17 citations
Semantic Scholar
Response to MAPK pathway inhibitors in BRAF V600M‐mutated metastatic melanoma
S. Parakh, C. Murphy, David K. Lau, J. Cebon +1 more
2015Journal of Clinical Pharmacy and Therapeutics16 citations Open access
Semantic Scholar
POLEM: Avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III dMMR or POLE exonuclease domain mutant colon cancer—A phase III randomized study.
David K. Lau, D. Cunningham, A. Gillbanks, R. Crux +11 more
2019Journal of Clinical Oncology11 citations
Semantic Scholar
Sex-related disparities in outcomes of cholangiocarcinoma patients in treatment trials
M. Ledenko, S. Antwi, S. Arima, Julia Driscoll +16 more
2022Frontiers in Oncology10 citations Open access
Semantic Scholar
Safety and efficacy review of aflibercept for the treatment of metastatic colorectal cancer
David K. Lau, Justin Mencel, I. Chau
2022Expert Opinion on Drug Safety10 citations
Semantic Scholar
SARS-CoV-2 Vaccine Immunogenicity in Patients with Gastrointestinal Cancer Receiving Systemic Anti-Cancer Therapy
David K. Lau, M. Aresu, T. Planche, A. Tran +22 more
2022The Oncologist7 citations Open access
Semantic Scholar
Update on optimal treatment for metastatic colorectal cancer from the AGITG expert meeting: ESMO congress 2019
David K. Lau, M. Burge, A. Roy, I. Chau +8 more
2020Expert Review of Anticancer Therapy6 citations Open access
Semantic Scholar
A single-centre experience of patients with metastatic melanoma enrolled in a dabrafenib named patient programme
David K. Lau, M. Andrews, N. Turner, A. Azad +2 more
2014Melanoma research6 citations
Semantic Scholar
Neoadjuvant and adjuvant multimodality therapies in resectable esophagogastric adenocarcinoma
David K. Lau, A. Athauda, I. Chau
2021Expert Opinion on Pharmacotherapy5 citations
Semantic Scholar
Dual Targeting of FGFR3 and ERBB3 Enhances The E�cacy of FGFR Inhibitors in FGFR3 Fusion-Driven Bladder Cancer
A. Weickhardt, Olivia Newton-John, David K. Lau, Austen Lavis +2 more
20214 citations
Semantic Scholar
Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer
Benjamin R. Challoner, A. Woolston, David K. Lau, M. Buzzetti +35 more
2022bioRxiv2 citations Open access
Semantic Scholar
Real-world experience of regorafenib in patients with hepatocellular carcinoma: A multicenter United Kingdom study.
P. Ross, Yuk-Ting Ma, D. Palmer, M. Lythgoe +16 more
20202 citations
Semantic Scholar
POD1UM-303/INTERAACT2 subgroup analyses and impact of delayed retifanlimab treatment on outcomes in patients with squamous cell carcinoma of the anal canal (SCAC).
M. Fakih, Rebecca Muirhead, A. Scott, M. Narang +16 more
2025Journal of Clinical Oncology1 citations
Semantic Scholar
Abstract CT304: Narmafotinib (AMP945) in combination with gemcitabine and nab-paclitaxel in first-line patients with advanced pancreatic cancer (ACCENT trial) a Phase 1b 2a study-Interim analysis
T. Cock, Sumitra Ananda, Choong-Kun Lee, N. Pavlakis +14 more
2026Cancer Research0 citations
Semantic Scholar
Abstract PR012: Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer
Benjamin R. Challoner, A. Woolston, David K. Lau, M. Buzzetti +13 more
2022Cancer Research0 citations
Semantic Scholar
Abstract A002: Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer
Benjamin R. Challoner, A. Woolston, David K. Lau, M. Buzzetti +13 more
2022Cancer Research0 citations
Semantic Scholar
Dual targeting of FGFR3 and the ERBB receptor family or AXL enhances the efficacy of FGFR inhibitors in FGFR3 fusion-driven bladder cancer
David K. Lau, M. Hodgson-Garms, Austen Lavis, Ian Y Luk +5 more
20210 citations Open access
Semantic Scholar
Cytokine release syndrome in a patient with colorectal cancer following vaccination with BNT162b2 (tozinameran)
S. Turajlic, L. Au, A. Fendler, S. Shepherd +28 more
20210 citations Open access
Semantic Scholar
453P Routine DPYD mutation testing for patients receiving fluoropyrimidines for gastrointestinal (GI) cancers: Real world experience in a tertiary UK oncology centre
David K. Lau, C. Fong, F. Arouri, L. Cortez +11 more
2021Annals of Oncology0 citations Open access
Semantic Scholar
Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study
David K. Lau, R. Tay, Yvonne H. Yeung, F. Chionh +6 more
2018British Journal of Cancer0 citations Open access
Semantic Scholar

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I. Chau — researcher profile on SciRah
N. Starling×10
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A. Weickhardt×6

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Ian Y Luk — researcher profile on SciRah